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Paediatrics and International Child Health Volume 40, 2020 - Issue 1
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Articles

Epidemiology of invasive bacterial infections in pneumococcal conjugate vaccine-vaccinated and -unvaccinated children under 5 years of age in Soweto, South Africa: a cohort study from a high-HIV burden setting

Siobhan L. JohnstoneMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;Department of Science and Technology/National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2033-270XView further author information
ORCID Icon,
David P. MooreDepartment of Paediatrics and Child Health, Chris Hani Baragwanath Academic Hospital and University of the Witwatersrand, Johannesburg, South AfricaORCID Iconhttps://orcid.org/0000-0001-6091-1605View further author information
ORCID Icon,
Keith P. KlugmanMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;Department of Science and Technology/National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South AfricaView further author information
,
Shabir A. MadhiMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;Department of Science and Technology/National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South AfricaORCID Iconhttps://orcid.org/0000-0002-7629-0636View further author information
ORCID Icon &
Michelle J. GroomeMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;Department of Science and Technology/National Research Foundation, Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South AfricaORCID Iconhttps://orcid.org/0000-0001-5893-3725View further author information
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Pages 50-57 | Received 29 Jan 2019, Accepted 21 May 2019, Published online: 03 Jun 2019

References

  • Enwere G, Biney E, Cheung Y, et al. Epidemiologic and clinical characteristics of community-acquired invasive bacterial infections in children aged 2–29 months in The Gambia. Pediatr Infect Dis J. 2006;25:700–705.
  • Dramowski A, Cotton MF, Rabie H, et al. Trends in paediatric bloodstream infections at a South African referral hospital. BMC Pediatr. 2015;15:33–44.
  • Zar HJ, Barnett W, Stadler A, et al. Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: a nested case-control study of the Drakenstein child health study. Lancet. 2016;4:463–472.
  • Nunes MC, von Gottberg A, de Gouveia L, et al. The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis. Aids. 2011;25:453–462.
  • von Gottberg A, de Gouveia L, Tempia S, et al. Effects of vaccination on invasive pneumococcal disease in South Africa. N Engl J Med. 2014;371:1889–1899.
  • Cohen C, von Mollendorf C, de Gouveia L, et al. Effectiveness of 7-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in HIV-infected and -uninfected children in South Africa: a matched case-control study. Clin Infect Dis. 2014;59:808–818.
  • Klugman KP, Madhi SA, Huebner RE, et al. A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. N Engl J Med. 2003;346:1341–1348.
  • Aly H, Herson V, Duncan A, et al. Is bloodstream infection preventable among premature infants? A tale of two cities. Pediatrics. 2005;115:1513–1518.
  • Greenhow TL, Hung Y, Herz A. Bacteremia in children 3 to 36 months old after introduction of conjugated pneumococcal vaccines. Pediatrics. 2017;139:e 20162098.
  • Bourgeois AL, Wierzba TF, Walker RI. Status of vaccine research and development for enterotoxigenic Escherichia coli. Vaccine. 2016;34:2880–2886.
  • Morello W, La Scola C, Alberici I, et al. Acute pyelonephritis in children. Pediatr Nephrol. 2016;31:1253–1265.
  • Cools P. The role of Escherichia coli in reproductive health: state of the art. Res Microbiol. 2017;168:892–901.
  • Poolman JT, Wacker M. Extraintestinal pathogenic Escherichia coli, a common human pathogen: challenges for vaccine development and progress in the field. J Infect Dis. 2016;213:6–13.
  • Madhi SA. Introduction of the pneumococcal conjugate vaccine into the South African public immunisation programme: dawn of a new era? S Afr J Epidemiol Infect. 2008;23:5–9.
  • Actuarial Society of South Africa. AIDS and demographic model; 2008. [cited 2017 Dec 18] Available from: https://www.actuarialsociety.org.za/downloads/committee-activities/aids-models/
  • Jallow S, Madhi SA. Pneumococcal conjugate vaccine in HIV-infected and HIV-exposed, uninfected children. Expert Rev Vaccines. 2017;16:453–465.
  • Buys H, Muloiwa R, Bamford C, et al. Klebsiella pneumoniae bloodstream infections at a South African children’s hospital 2006–2011, a cross-sectional study. BMC Infect Dis. 2016;16:570.
  • Bogaert D, van Belkum A, Sluijter M, et al. Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children. Lancet. 2004;363:1871–1872.
  • Reiss-Mandel A, Regev-Yochay G. Staphylococcus aureus and Streptococcus pneumoniae interaction and response to pneumococcal vaccination: myth or reality? Hum Vaccin Immunother. 2016;12:351–357.

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