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Articles

Leptospirosis in the elderly: the role of age as a predictor of poor outcomes in hospitalized patients

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References

  • Bharti AR, Nally JE, Ricaldi JN, et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis. 2003;3:757–771.
  • Pappas G, Papadimitriou P, Siozopoulou Y, et al. The globalization of leptospirosis: worldwide incidence trends. Int J Infect Dis. 2008;12:315–357.
  • Daher EF, Silva GB, Lima RSA, et al. Different patterns in a cohort of patients with severe leptospirosis (weil syndrome): effects of an educational program in an endemic area. Am J Trop Med Hyg. 2011;85:479–484.
  • Daher EF, Carvalho GSG, Soares DS, et al. Changing patterns in leptospirosis: a three-decade study in Brazil. Int J Infect Dis. 2017;60:4–10.
  • Taylor AJ, Paris HD, Newton PN. A systematic review of the mortality from untreated leptospirosis. PLoS Negl Trop Dis. 2015;9(6):e0003866.
  • Traxler RM, Callinan LS, Holman RC, et al. Leptospirosis-associated hospitalizations, United States, 1998–2009. Emerg Infect Dis. 2014;20:1273–1279.
  • Gancheva GI. Leptospirosis in elderly patients. Braz J Infect Dis. 2013;17(5):592–595.
  • Kidney Disease Outcomes Quality Initiative. KDIGO clinical practice guidelines for acute kidney injury – summary of recommendation statements. Kidney Int Suppl. 2012;2:1–138.
  • Adler B, de la Peña Moctezuma A. Leptospira and leptospirosis. Vet Microbiol. 2010;140:287–296.
  • McBride AJ, Athanazio DA, Reis MG, et al. Leptospirosis. Curr Opin Infect Dis. 2005;18:376–386.
  • Levett PN. Leptospirosis. Clin Microbiol Rev. 2001;14:296–326.
  • Nardone A, Capek I, Baranton G, et al. Risk factors for leptospirosis in metropolitan France: results of a national case-control study, 1999–2000. Clin Infect Dis. 2004;39::751–753.
  • Haake DA, Dundoo M, Cader R, et al. Leptospirosis, water sports, and chemoprophylaxis. Clin Infect Dis. 2002;34:e40–e43.
  • Guerra-Silveira F, Abad-Franch F. Sex bias in infectious disease epidemiology: patterns and processes. PLoS One. 2013;8(4):e62390.
  • Seguro AC, Andrade L. Pathophysiology of leptospirosis. Shock. 2013;39:17–23.
  • Meeks WM. Pathophysiology of hypertension in the elderly. Semin Nephrol. 2002 Jan;22(1):65–70.
  • Dolhnikoff M, Mauad T, Bethlem EP, et al. Pathology and pathophysiology of pulmonary manifestations in leptospirosis. Braz J Infect Dis. 2007;11:142–148.
  • Luks AM, Lakshminarayanan S, Hirschmann JV. Leptospirosis presenting as diffuse alveolar hemorrhage: case report and literature review. Chest. 2003;123:639–643.
  • Estavoyer JM, Racadot E, Couetdic G, et al. Tumor necrosis factor in patients with leptospirosis. Rev Infect Dis. 1991;13:1245–1246.
  • Reis EA, Hagan JE, Ribeiro GS, et al. Cytokine response signatures in disease progression and development of severe clinical outcomes for leptospirosis. PLoS Negl Trop Dis. 2013;7:e2457.
  • Papa A, Kotrotsiou T. Cytokines in human leptospirosis. Trans R Soc Trop Med Hyg. 2015;109:749–754.
  • Daher EF, Lima RSA, Silva Júnior GB, et al. Clinical presentation of leptospirosis: a retrospective study of 201 patients in a metropolitan city of Brazil. Braz J Infect Dis. 2010;14:3–10.
  • Andrade L, Daher EF, Seguro AC. Leptospiral nephropathy. Semin Nephrol. 2008;28:383–394.
  • Penna D, de Brito T, Pupo AA, et al. Kidney biopsy in human Leptospirosis. Am J Trop Med Hyg. 1963;12:896–901.
  • Araujo ER, Seguro AC, Spichler A, et al. Acute kidney injury in human leptospirosis: an immunohistochemical study with pathophysiological correlation. Virchows Arch. 2010;456:367–375.
  • Magaldi AJ, Yasuda PN, Kudo LH, et al. Renal involvement in Leptospirosis: a pathophysiology study. Nephron. 1992;62:332–339.
  • Daher EDF, de Abreu KLS, da Silva Junior GB. Leptospirosis-associated acute kidney injury. J Bras Nefrol. 2010;32:400–407.
  • Andrade L, Cleto S, Seguro AC. Door-to-dialysis time and daily hemodialysis in patients with leptospirosis: impacton mortality. Clin J Am Soc Nephrol. 2007;2:739–744.
  • Seabra VF, Balk EM, Liangos O, et al. Timing of renal replacement therapy initiation in acute renal failure: a meta-analysis. Am J Kidney Dis. 2008; 52: 272–284.
  • Cleto SA, Rodrigues CE, Malaque CM, et al. Hemodiafiltration decreases serum levels of inflammatory mediators in severe leptospirosis: a prospective study. PLoS One. 2016;11:e0160010.
  • Navinan MR, Rajapakse S. Cardiac involvement in leptospirosis. Trans R Soc Trop Med Hyg. 2012;106(9):515–520.
  • Dupont H, Dupont-Perdrizet D, Perie JL, et al. Leptospirosis: prognostic factors associated with mortality. Clin Infect Dis. 1997;25:720–724.
  • Soares DS, Galdino GS, Rodrigues BC, et al. Arrhythmias in leptospirosis-associated acute kidney injury: a case series. Braz J Infect Dis. 2017;21:209–210.
  • Daher EF, Vieira AP, Jacinto CN, et al. Differences among children, adolescents and adults with severe leptospirosis: a comparative analysis. Indian J Nephrol. 2014;24:166–170.
  • Spichler A, Athanazio DA, Vilaça P, et al. Comparative analysis of severe pediatric and adult leptospirosis in São Paulo, Brazil. Am J Trop Med Hyg. 2012;86:306–308.

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