Bloodstream infections and antibiotic resistance patterns: a six-year surveillance study from southern Italy

References

• Viscoli C. Bloodstream infections: the peak of the iceberg. Virulence. 2016;7(3):248–251.
   PubMed Web of Science ®Google Scholar
• Kern WV, Rieg S. Burden of bacterial bloodstream infection-a brief update on epidemiology and significance of multidrug-resistant pathogens. Clin Microbiol Infect. 2020 Feb;26(2):151–157. DOI:10.1016/j.cmi.2019.10.031.
   PubMed Web of Science ®Google Scholar
• Cohlen B, Bijkerk A, Van der Poel S, et al. IUI: review and systematic assessment of the evidence that supports global recommendations. Hum Reprod Update. 2018;24(3):300–319.
   PubMed Web of Science ®Google Scholar
• Iacchini S, Sabbatucci M, Gagliotti C, et al. Bloodstream infections due to carbapenemase-producing Enterobacteriaceae in Italy: results from nationwide surveillance, 2014 to 2017. Euro Surveill. 2019;24(5):1800159.
   PubMedGoogle Scholar
• Sorveglianza nazionale delle batteriemie da enterobatteri produttori di carbapenemasi. Rapporto 2013–2016. Rapporti ISTISAN 17/18. [cited 2018 Aug 21]. Available from: http://old.iss.it/binary/publ/cont/17_18_web.pdf
   Google Scholar
• Kunz Coyne AJ, Casapao AM, Isache C, et al. Influence of antimicrobial stewardship and molecular rapid diagnostic tests on antimicrobial prescribing for extended-spectrum beta-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in bloodstream infection. Microbiol Spectr. 2021;9(2):e0046421.
   PubMed Web of Science ®Google Scholar
• Schöneweck F, Schmitz RPH, Rißner F, et al. The epidemiology of bloodstream infections and antimicrobial susceptibility patterns in Thuringia, Germany: a five-year prospective, state-wide surveillance study (AlertsNet). Antimicrob Resist Infect Control. 2021;10(1):132.
   PubMed Web of Science ®Google Scholar
• Timsit JF, Ruppé E, Barbier F, et al. Bloodstream infections in critically ill patients: an expert statement. Intensive Care Med. 2020;46(2):266–284.
   PubMed Web of Science ®Google Scholar
• Opintan JA, Newman MJ. Prevalence of antimicrobial resistant pathogens from blood cultures: results from a laboratory based nationwide surveillance in Ghana. Antimicrob Resist Infect Control. 2017;6:64.
   PubMed Web of Science ®Google Scholar
• Licata F, Quirino A, Pepe D, et al.Antimicrobial resistance in pathogens isolated from blood cultures: a two-year multicenter hospital surveillance study in Italy. Antibiotics (Basel). 2020 Dec 24;10(1):10. DOI: 10.3390/antibiotics10010010.
   PubMed Web of Science ®Google Scholar
• Tängdén T, Giske CG. Global dissemination of extensively drug-resistant carbapenemase-producing Enterobacteriaceae: clinical perspectives on detection, treatment and infection control. J Intern Med. 2015;277(5):501–512.
   PubMed Web of Science ®Google Scholar
• Bellino S, Iacchini S, Monaco M, et al. AR–ISS: sorveglianza Nazionale Dell’antibiotico–resistenza. Roma, Italy: Dati 2019; Istituto Superiore di Sanità; 2020. pp. 4–9.
   Google Scholar
• Birru M, Woldemariam M, Manilal A, et al. Bacterial profile, antimicrobial susceptibility patterns, and associated factors among bloodstream infection suspected patients attending Arba Minch General Hospital, Ethiopia. Sci Rep. 2021 Aug 5;11(1):15882. DOI:10.1038/s41598-021-95314-x. PMID: 34354138; PMCID: PMC8342484.
   PubMed Web of Science ®Google Scholar
• Thomas SR, Jose CS, Damodaran D, et al. A tertiary care hospital based study on antimicrobial sensitivity pattern among septic patients. Int J Cur Res Revi. 2019;11(10):7. DOI:10.31782/IJCRR.2019.11102.
   Google Scholar
• Brannon JR, Dunigan TL, Beebout CJ, et al. Invasion of vaginal epithelial cells by uropathogenic Escherichia coli. Nat Commun. 2020 Jun 4;11(1):2803. DOI:10.1038/s41467-020-16627-5.
   PubMed Web of Science ®Google Scholar
• Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016 Oct;16(10):626–638. DOI:10.1038/nri.2016.90. Epub 2016 Aug 22. PMID: 27546235.
   PubMed Web of Science ®Google Scholar
• Laupland KB, Pasquill K, Steele L, et al. Burden of bloodstream infection in older persons: a population-based study. BMC Geriatr. 2021 Jan 7;21(1):31. DOI:10.1186/s12877-020-01984-z.
   PubMed Web of Science ®Google Scholar
• Di Carlo P, Serra N, Lo Sauro S, et al. Epidemiology and pattern of resistance of gram-negative bacteria isolated from blood samples in hospitalized patients: a single center retrospective analysis from southern Italy. Antibiotics (Basel). 2021 Nov 16;10(11):1402. DOI:10.3390/antibiotics10111402.
   PubMed Web of Science ®Google Scholar
• Deku JG, Dakorah MP, Lokpo SY, et al. The epidemiology of bloodstream infections and antimicrobial susceptibility patterns: a nine-year retrospective study at St. Dominic Hospital, Akwatia, Ghana. J Trop Med. 2019 Sep 19;2019:6750864. DOI:10.1155/2019/6750864.
   PubMed Web of Science ®Google Scholar
• Lavano MA, Foglia F, Della Rocca MT, et al. Epidemiology of multi and extensively drug resistance Pseudomonas aeruginosa infections from university hospital “Luigi Vanvitelli” of Naples. J Community Med Public Health. 4:199. DOI:10.29011/2577-2228.100099.
   Google Scholar
• Pignataro D, Foglia F, Della Rocca MT, et al. Methicillin-Resistant Staphylococcus aureus: epidemiology and antimicrobial susceptibility experiences from the university hospital ‘Luigi Vanvitelli’ of Naples. Pathog Glob Health. 2020 Dec;114(8):451–456. DOI:10.1080/20477724.2020.1827197.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Sun Z, Tian L. Antimicrobial resistance among pathogens causing bloodstream infections: a multicenter surveillance report over 20 years (1998–2017). Infect Drug Resist. 2022;15:249–260.
   PubMed Web of Science ®Google Scholar
• Lupia T, Roberto G, Scaglione L, et al. Clinical and microbiological characteristics of bloodstream infections caused by Enterococcus spp. within internal medicine wards: a two-year single-centre experience. Intern Emerg Med. 2022 Jun;17(4):1129–1137. DOI:10.1007/s11739-022-02926-w.
   PubMed Web of Science ®Google Scholar
• Billington E, Phang S, Gregson D, et al. Incidence, risk factors, and outcomes for Enterococcus spp. blood stream infections: a population-based study. Int J Infect Dis. 2014;26:76–82.
   PubMed Web of Science ®Google Scholar
• Giannella M, Bartoletti M, Gatti M, et al. Advances in the therapy of bacterial bloodstream infections. Clin Microbiol Infect. 2020 Feb;26(2):158–167. DOI:10.1016/j.cmi.2019.11.001.
   PubMed Web of Science ®Google Scholar
• Peirano G, Pitout JDD. Extended-Spectrum β-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options. Drugs. 2019;79:1529–1541. Epub ahead of print: DOI:10.1007/s40265-019-01180-3.
   PubMed Web of Science ®Google Scholar
• Diekema DJ, Hsueh PR, Mendes RE, et al. The microbiology of bloodstream infection: 20-year trends from the SENTRY antimicrobial surveillance program. Antimicrob Agents Chemother. 2019;63:e00355–e00419.
   PubMed Web of Science ®Google Scholar
• Gutiérrez-Gutiérrez B, Rodríguez-Baño J. Current options for the treatment of infections due to extended-spectrum beta-lactamase-producing Enterobacteriaceae in different groups of patients. Clin Microbiol Infect. 2019 Aug;25(8):932–942. DOI:10.1016/j.cmi.2019.03.030.
   PubMed Web of Science ®Google Scholar
• Barchitta M, Quattrocchi A, Maugeri A, et al. Antibiotic consumption and resistance during a 3-year period in Sicily, Southern Italy. Int J Environ Res Public Health. 2019;16(13):2253.
   PubMed Web of Science ®Google Scholar
• Schwarz S, Johnson AP. Transferable resistance to colistin: a new but old threat. J Antimicrob Chemother. 2016;71:2066–2070.
   PubMed Web of Science ®Google Scholar
• Zafer MM, El-Mahallawy HA, Abdulhak A, et al. Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients. Ann Clin Microbiol Antimicrob. 2019 Dec 12;18(1):40. DOI:10.1186/s12941-019-0339-4.
   PubMed Web of Science ®Google Scholar
• Klein EY, Mojica N, Jiang W, et al. Trends in methicillin-resistant Staphylococcus aureus hospitalizations in the United States, 2010-2014. Clin Infect Dis. 2017 Nov 13;65(11):1921–1923. DOI:10.1093/cid/cix640. PMID: 29020322.
   PubMed Web of Science ®Google Scholar
• Lawes T, Lopez-Lozano JM, Nebot CA, et al. Effects of national antibiotic stewardship and infection control strategies on hospital-associated and community-associated methicillin-resistant Staphylococcus aureus infections across a region of Scotland: a non-linear time-series study. Lancet Infect Dis. 2015 Dec;15(12):1438–1449. DOI:10.1016/S1473-3099(15)00315-1.
   PubMed Web of Science ®Google Scholar
• Chen Y, Ji J, Ying C, et al.Blood bacterial resistant investigation collaborative system (BRICS) report: a national surveillance in China from 2014 to 2019. Antimicrob Resist Infect Control. 2022 Jan 24;11(1):17. DOI: 10.1186/s13756-022-01055-5.
   PubMed Web of Science ®Google Scholar
• Meletis G. Carbapenem resistance: overview of the problem and future perspectives. Ther Adv Infect Dis. 2016 Feb;3(1):15–21. DOI:10.1177/2049936115621709.
   PubMed Web of Science ®Google Scholar
• Hu F, Guo Y, Yang Y, et al.Resistance reported from China antimicrobial surveillance network (CHINET) in 2018. Eur J Clin Microbiol Infect Dis. 2019 Dec;38(12):2275–2281. DOI:10.1007/s10096-019-03673-1. Epub 2019 Sep 2. PMID: 31478103.
   PubMed Web of Science ®Google Scholar
• Ambretti S, Bassetti M, Clerici P, et al. Screening for carriage of carbapenem-resistant Enterobacteriaceae in settings of high endemicity: a position paper from an Italian working group on CRE infections. Antimicrob Resist Infect Control. 2019 Aug 13;8:136. DOI:10.1186/s13756-019-0591-6.
   PubMed Web of Science ®Google Scholar
• Iacchini S, Sabbatucci M, Gagliotti C, et al. Bloodstream infections due to carbapenemase-producing Enterobacteriaceae in Italy: results from nationwide surveillance, 2014 to 2017. Euro Surveill. 2019 Jan;24(5):1800159. DOI:10.2807/1560-7917.ES.2019.24.5.1800159.
   PubMedGoogle Scholar
• Durante-Mangoni E, Bertolino L, Mastroianni C, et al. Complicated carbapenem-resistant infections: a treatment pathway analysis in Italian sites. Infez Med. 2021 Sep 10;29(3):434–449. DOI:10.53854/liim-2903-15.
   PubMedGoogle Scholar
• European Centre for Disease Prevention and Control. Antimicrobial resistance in the EU/EEA (EARSNet) - annual epidemiological report 2019. Stockholm: ECDC; 2020.
   Google Scholar
• WHO Regional Office for Europe/European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2022 – 2020 data. Copenhagen: WHO Regional Office for Europe; 2022.
   Google Scholar