COVID-19 vaccine acceptance and hesitancy in Indian context: a systematic review and meta-analysis

References

• Ackah M, Ameyaw L, Gazali Salifu M, et al. COVID-19 vaccine acceptance among health care workers in Africa: a systematic review and meta-analysis. Plos One. 2022; 17(5): e0268711. doi: 10.1371/journal.pone.0268711.
   PubMed Web of Science ®Google Scholar
• Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229): 1054–1062. doi: 10.1016/S0140-6736(20)30566-3.
   PubMed Web of Science ®Google Scholar
• Patwary MM, Alam MA, Bardhan M, et al. COVID-19 vaccine acceptance among low- and lower-middle-income countries: a rapid systematic review and meta-analysis. Vaccines. 2022; 10(3): 427–447. doi: 10.3390/vaccines10030427.
   Web of Science ®Google Scholar
• Lu H, Stratton CW, Tang YW Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020; 92(4): 401–402. doi: 10.1002/jmv.25678.
   PubMed Web of Science ®Google Scholar
• Andrews MA, Areekal B, Rajesh KR, et al. First confirmed case of COVID-19 infection in India: a case report. Indian J Med Res. 2020; 151(5): 490–492. doi: 10.4103/ijmr.IJMR_2131_20.
   PubMed Web of Science ®Google Scholar
• Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Biomed. 2020;91(1):157–160. doi: 10.23750/abm.v91i1.9397
   PubMedGoogle Scholar
• Zirpe KG, Dixit S, Kulkarni AP, et al. The second- vs first-wave COVID-19: more of the same or a lot worse? a comparison of mortality between the two waves in patients admitted to intensive care units in nine hospitals in Western Maharashtra. Indian J Crit Care Med. 2021; 25(12): 1343–1348. doi: 10.5005/jp-journals-10071-24042.
   PubMed Web of Science ®Google Scholar
• Lauring AS, Malani PN Variants of SARS-CoV-2. JAMA. 2021; 326(9): 880.10.1001/jama.2021.14181
   Web of Science ®Google Scholar
• Ranjan R, Sharma A, Verma MK Characterisation of the second wave of COVID-19 in India. MedRxiv. 2021. https://www.medrxiv.org/content/10.1101/2021.04.17.21255665v2.full.pdf
   Google Scholar
• Mohapatra RK, Sarangi AK, Kandi V, et al. Omicron (B.1.1.529 variant of SARS-CoV-2); an emerging threat: current global scenario. J Med Virol. 2022; 94(5): 1780–1783. doi: 10.1002/jmv.27561.
   PubMed Web of Science ®Google Scholar
• Joshi A, Kaur M, Kaur R, et al. Predictors of COVID-19 vaccine acceptance, intention, and hesitancy: a scoping review. Front Public Health. 2021;9:698111. doi: 10.3389/fpubh.2021.698111
   PubMed Web of Science ®Google Scholar
• Li H, Liu SM, Yu XH, et al. Coronavirus disease 2019 (COVID-19): current status and future perspectives. Int J Antimicrob Agents. 2020; 55(5): 105951. doi: 10.1016/j.ijantimicag.2020.105951.
   PubMed Web of Science ®Google Scholar
• Worldometer. India population. [Cited 2023 Jan 3]. Available from: https://www.worldometers.info/world-population/india-population/
   Google Scholar
• Marzo RR, Ahmad A, Islam MS, et al. Perceived COVID-19 vaccine effectiveness, acceptance, and drivers of vaccination decision-making among the general adult population: a global survey of 20 countries. PLoS Negl Trop Dis. 2022 28;16(1):e0010103. doi: 10.1371/journal.pntd.0010103
   PubMed Web of Science ®Google Scholar
• Askarian M, Semenov A, Llopis F, et al. The COVID-19 vaccination acceptance/hesitancy rate and its determinants among healthcare workers of 91 countries: a multicenter cross-sectional study. EXCLI J. 2022;21:93–103. doi: 10.17179/excli2021-4439
   PubMed Web of Science ®Google Scholar
• Government of India. Ministry of Health and family Welfare: covid-19 statistics. [cited 2023 Jan 4]. Available from: https://www.mohfw.gov.in/
   Google Scholar
• Truong J, Bakshi S, Wasim A, et al. What factors promote vaccine hesitancy or acceptance during pandemics? A systematic review and thematic analysis. Health Promot Int. 2022; 37(1):daab105. doi: 10.1093/heapro/daab105.
   PubMed Web of Science ®Google Scholar
• Sachdeva S, Saluja H, Mani A Cognizance, adverse effects and motivation regarding COVID-19 vaccination amongst health care professionals: a cross-sectional study. Dent Med Probl. 2022; 59(1): 13–19. doi: 10.17219/dmp/145757.
   PubMed Web of Science ®Google Scholar
• Kashte S, Gulbake A, El-Amin SF III, et al. COVID-19 vaccines: rapid development, implications, challenges and future prospects. Hum Cell. 2021 May;34(3):711–733. doi: 10.1007/s13577-021-00512-4
   PubMed Web of Science ®Google Scholar
• COVID-19 vaccine tracker and landscape. Geneva: World Health Organization; 2021. [cited 2022 Oct 21]. Available from: https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines.
   Google Scholar
• Bharat Biotech and ICMR Announce interim results from phase 3 trials of COVAXIN®. Hyderabad: Bharat Biotech. 2021 Apr 21. [cited 2022 25 Oct]. Available from: https://www.bharatbiotech.com/images/press/covaxin-phase3-clinical-trials-interim-results.pdf.
   Google Scholar
• Government of India, Ministry of Health and family Welfare. FAQs on COVID-19 vaccines and vaccination program. https://www.mohfw.gov.in/pdf/FAQsCOVID19vaccinesvaccinationprogramWebsiteupload27Sep.pdf
   Google Scholar
• Purohit N, Chugh Y, Bahuguna P, et al. COVID-19 management: the vaccination drive in India. Health Policy Technol. 2022;11(2):100636. doi: 10.1016/j.hlpt.2022.100636.
   PubMed Web of Science ®Google Scholar
• World Health Organization. (2019). Ten Threats to global health in 2019. [cited 2022 May 11]. Ten threats to global health in 2019 (who.int).
   Google Scholar
• MacDonald NE, SAGE Working Group on Vaccine Hesitancy. Vaccine hesitancy: definition, scope and determinants. Vaccine. 2015;33(34):4161–4164. doi: 10.1016/j.vaccine.2015.04.036
   PubMed Web of Science ®Google Scholar
• Government of India. Ministry of Health and family Welfare: cumulative coverage report of COVID-19 vaccination. [cited Jan 4, 2023]. Available from: https://www.mohfw.gov.in/pdf/CummulativeCovidVaccinationReport04Jan2023.pdf
   Google Scholar
• Randolph HE, Barreiro LB. Herd immunity: understanding COVID-19. Immunity. 2020;52(5):737–741. doi: 10.1016/j.immuni.2020.04.012
   PubMed Web of Science ®Google Scholar
• Centre for Reviews and Dissemination. York Publ Services. 2009. (no.4). https://www.york.ac.uk/media/crd/Systematic_Reviews.pdf.
   Google Scholar
• Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151(4): 264–269, W64. doi: 10.7326/0003-4819-151-4-200908180-00135.
   PubMed Web of Science ®Google Scholar
• Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Syst Rev. 2021; 10(1): 89. doi: 10.1186/s13643-021-01626-4.
   PubMed Web of Science ®Google Scholar
• Sharun K, Rahman CF, Haritha CV, et al. COVID-19 vaccine acceptance: beliefs and barriers associated with vaccination among the general population in India. J Exp Biol Agric Sci. 2020; 8(Spl–1–SARS–CoV–2): S210–18. 10.18006/2020.8(Spl-1-SARS-CoV-2).S210.S218
   Google Scholar
• Gautam A, Dhara B, Mukherjee D, et al. A digital survey on the acceptance and affordability of COVID-19 vaccine among the people of West Bengal, India - a survey based study. MedRxiv. 2020. https://www.medrxiv.org/content/medrxiv/early/2020/11/16/2020.11.13.20229534.full.pdf
   Google Scholar
• Leelavathy M, Messaline S, Ramachandran D, et al. Attitude towards COVID-19 vaccination among the public in Kerala: a cross sectional study. J Family Med Prim Care. 2021; 10(11): 4147–4152. doi: 10.4103/jfmpc.jfmpc_583_21.
   PubMedGoogle Scholar
• Ain SN, Ahmad R, Qulsum R, et al. Potential vaccine hesitancy regarding COVID-19 vaccines in Kashmiri population. J Educ Health Promot. 2021;10:436. doi: 10.4103/jehp.jehp_40_21
   PubMedGoogle Scholar
• Kumar R, Bairwa M, Beniwal K, et al. COVID-19 vaccine acceptability, determinants of potential vaccination, and hesitancy in public: a call for effective health communication. J Educ Health Promot. 2021;10:392. doi: 10.4103/jehp.jehp_327_21
   PubMedGoogle Scholar
• Anandraj J, Krishnamoorthy Y, Sivanantham P, et al. Impact of second wave of COVID-19 pandemic on the hesitancy and refusal of COVID-19 vaccination in Puducherry, India: a longitudinal study. Hum Vaccin Immunother. 2021; 17(12): 5024–5029. doi: 10.1080/21645515.2021.2000262.
   PubMed Web of Science ®Google Scholar
• Ekstrand ML, Heylen E, Gandhi M, et al. COVID-19 vaccine hesitancy among PLWH in South India: implications for vaccination campaigns. J Acquir Immune Defic Syndr. 2021; 88(5): 421–425. doi: 10.1097/QAI.0000000000002803.
   PubMed Web of Science ®Google Scholar
• Uvais NA COVID-19 vaccine hesitancy among patients with psychiatric disorders. Prim Care Companion CNS Disord. 2021; 23(6): 21br03028. doi: 10.4088/PCC.21br03028.
   PubMedGoogle Scholar
• Umakanthan S, Patil S, Subramaniam N, et al. COVID-19 vaccine hesitancy and resistance in India explored through a population-based longitudinal survey. Vaccines (Basel). 2021; 9(10): 1064. doi: 10.3390/vaccines9101064.
   PubMed Web of Science ®Google Scholar
• Chandani S, Jani D, Sahu PK, et al. COVID-19 vaccination hesitancy in India: state of the nation and priorities for research. Brain Behav Immun Health. 2021;18:100375. doi: 10.1016/j.bbih.2021.100375
   PubMedGoogle Scholar
• Kishore J, Venkatesh U, Ghai G, et al. Perception and attitude towards COVID-19 vaccination: a preliminary online survey from India. J Family Med Prim Care. 2021;10(8):3116–3121. doi: 10.4103/jfmpc.jfmpc_2530_20
   PubMedGoogle Scholar
• Danabal KGM, Magesh SS, Saravanan S, et al. Attitude towards COVID-19 vaccines and vaccine hesitancy in urban and rural communities in Tamil Nadu, India - a community based survey. BMC Health Serv Res. 2021; 21(1): 994. doi: 10.1186/s12913-021-07037-4.
   PubMed Web of Science ®Google Scholar
• Gaur P, Agrawat H, Shukla A. COVID-19 vaccine hesitancy in patients with systemic autoimmune rheumatic disease: an interview-based survey. Rheumatol Int. 2021;41(9):1601–1605. doi: 10.1007/s00296-021-04938-9
   PubMed Web of Science ®Google Scholar
• Jacob J, Stephen S, Issac A, et al. Determinants of willingness for COVID-19 vaccine: implications for enhancing the proportion of vaccination among Indians. Cureus. 2021; 13(5): e15271. doi: 10.7759/cureus.15271.
   PubMed Web of Science ®Google Scholar
• Kumari A, Ranjan P, Chopra S, et al. Knowledge, barriers and facilitators regarding COVID-19 vaccine and vaccination programme among the general population: a cross-sectional survey from one thousand two hundred and forty-nine participants. Diabetes Metab Syndr. 2021; 15(3): 987–992. doi: 10.1016/j.dsx.2021.04.015.
   PubMed Web of Science ®Google Scholar
• Islam F, Agarwalla R, Panda M, et al. Assessment of the knowledge, preferences and concern regarding the prospective COVID-19 vaccine among adults residing in New Delhi, India - a cross-sectional study. J Family Med Prim Care. 2021; 10(6): 2369–2375. doi: 10.4103/jfmpc.jfmpc_2437_20.
   PubMedGoogle Scholar
• Bharadwaj AH, Ramachandra SC, Devaraju A, et al. Perception of indian citizens toward the available COVID-19 vaccines: need to create increased awareness. Perspect Clin Res. 2021;12(4):236–237. doi: 10.4103/picr.picr_97_21
   PubMedGoogle Scholar
• Shah SN, Shah D, Desai N, et al. Analysis of change in knowledge, attitude, and practices about COVID-19 following and awareness session in rural population of Western India. Ind Psychiatry J. 2021; 30(Suppl 1): S35–S40. doi: 10.4103/0972-6748.328786.
   PubMedGoogle Scholar
• Bhondve AS, Ingawale SM, Rajapurkar ND. COVID19 vaccine hesitancy and its determinants among healthcare workers and nonhealthcare workers: an online survey in India. J Clin Sci Res. 2021;10:212–220. doi: 10.4103/jcsr.jcsr_38_21
   Google Scholar
• Bhangale C, TSES I, Ramanand J, et al. Assessment of vaccine hesitancy for COVID-19 vaccines and evaluation of factors associated with it, among the residents of North Maharashtra Region, India. Natl J Physiol Pharm Pharmacol 2022; 12(4): 462–467. 10.5455/njppp.2022.12.09352202106102021
   Google Scholar
• Goruntla N, Chintamani SH, Bhanu P, et al. Predictors of acceptance and willingness to pay for the COVID-19 vaccine in the general public of India: a health belief model approach. Asian Pac J Trop Med. 2021; 14(4): 165–175. doi: 10.4103/1995-7645.312512.
   Web of Science ®Google Scholar
• Suresh A, Konwarh R, Singh AP, et al. Public awareness and acceptance of COVID-19 vaccine: an online cross-sectional survey, conducted in the first phase of vaccination drive in India. Res Square. 2021. doi: 10.21203/rs.3.rs-324238/v1.
   Google Scholar
• Dabas P, Raj KJ, John J, et al. Covid-19 vaccine acceptance and determinants–an online cross-sectional survey in Kerala, India. Natl J Comm Med. 2021; 12(12): 432–438. doi: 10.5455/njcm.20211021095953
   PubMedGoogle Scholar
• Bansal S, Gangwar AK, Sharma A, et al. Knowledge, attitude, practice, and post-infection effects regarding COVID-19, and vaccine acceptance among general people of North India-a multicentred cross-sectional study. Europe PMC. 2021. doi: 10.22541/au.162289618.82152279/v1.
   Google Scholar
• Lazarus JV, Wyka K, White TM, et al. Revisiting COVID-19 vaccine hesitancy around the world using data from 23 countries in 2021. Nat Commun. 2022;13(1):3801. doi: 10.1038/s41467-022-31441-x.
   PubMed Web of Science ®Google Scholar
• Raja D, Sasithra S .COVID-19 vaccine acceptance and its determinants among adult population of Chengalpattu district: a mixed-method study. J Comm Dis. 2022:68–74. Special Issue - COVID-19 & Other Communicable Disease. doi:10.24321/0019.5138.202211.
   Google Scholar
• Sharma P, Basu S, Mishra S, et al. COVID-19 vaccine acceptance and its determinants in the general population of Delhi, India: a state level cross-sectional survey. Cureus. 2022; 14(7): e26936. doi: 10.7759/cureus.26936.
   PubMed Web of Science ®Google Scholar
• Parthasarathi A, Puvvada RK, Shankar M, et al. Willingness to accept the COVID-19 vaccine and related factors among Indian adults: a cross-sectional study. Vaccines (Basel). 2022;10(7):1095. doi: 10.3390/vaccines10071095.
   PubMed Web of Science ®Google Scholar
• Achrekar GC, Batra K, Urankar Y, et al. Assessing COVID-19 booster hesitancy and its correlates: an early evidence from India. Vaccines (Basel). 2022 Jun;10(7):1048. doi: 10.3390/vaccines10071048
   PubMed Web of Science ®Google Scholar
• Gupta A, Christina S, Umar AY, et al. COVID-19 vaccine hesitancy among pregnant women: a facility-based cross-sectional study in Imphal, Manipur. Indian J Public Health. 2022;66(2):98–103. doi: 10.4103/ijph.ijph_1826_21
   PubMed Web of Science ®Google Scholar
• Kuchi S, Parida SP. COVID-19 vaccination hesitancy and attitude post-initiation of vaccination drive, a cross-sectional study across odisha. J Family Med Prim Care. 2022;11(5):1996–2001. doi: 10.4103/jfmpc.jfmpc_1862_21
   PubMedGoogle Scholar
• Mohanasundaram K, Santhanam S, Natarajan R, et al. Covid-19 vaccination in autoimmune rheumatic diseases: a multi-center survey from Southern India. Int J Of Rheum Dis. 2022; 25(9):1046–1052. doi: 10.1111/1756-185X.14378.
   PubMed Web of Science ®Google Scholar
• Sengupta M, Dutta S, Roy A, et al. Knowledge, attitude and practice survey towards COVID-19 vaccination: a mediation analysis. Int J Health Plann Manage. 2022; 37(4):2063–2080. doi: 10.1002/hpm.3449.
   PubMed Web of Science ®Google Scholar
• Joshi A, Surapaneni KM, Kaur M, et al. A cross sectional study to examine factors influencing COVID-19 vaccine acceptance, hesitancy and refusal in urban and rural settings in Tamil Nadu, India. Plos One. 2022; 17(6):e0269299. doi: 10.1371/journal.pone.0269299.
   PubMed Web of Science ®Google Scholar
• Romate J, Rajkumar E, Greeshma R. Using the integrative model of behavioural prediction to understand COVID-19 vaccine hesitancy behaviour. Sci Rep. 2022;12(1):9344. doi: 10.1038/s41598-022-12466-0
   PubMed Web of Science ®Google Scholar
• Kusuma YS, Kant S. COVID-19 vaccine acceptance and its determinants: a cross-sectional study among the socioeconomically disadvantaged communities living in Delhi, India. Vaccine: X. 2022;11:100171. doi: 10.1016/j.jvacx.2022.100171
   PubMedGoogle Scholar
• Khan IA, Bashar A, Tewari HC Attitude, perceptions and willingness to receive COVID-19 vaccine and its associated factors among general population of Uttar Pradesh, Northern India. Clin Epidemiol Glob Health. 2022:101040. doi: 10.1016/j.cegh.2022.101040.
   PubMedGoogle Scholar
• Khan Z, Khursheed SQ, Dar SA, et al. Vaccine hesitancy and Coronavirus disease-19: where do we stand? J Educ Health Promot. 2022;11:59. doi: 10.4103/jehp.jehp_642_21
   PubMedGoogle Scholar
• Kumari A, Mahey R, Kachhawa G, et al. Knowledge, attitude, perceptions, and concerns of pregnant and lactating women regarding COVID-19 vaccination: a cross-sectional survey of 313 participants from a tertiary care centre of North India. Diabetes Metab Syndr. 2022; 16(3):102449. doi: 10.1016/j.dsx.2022.102449.
   PubMed Web of Science ®Google Scholar
• Jetly S, Bhardwaj P, Arora G, et al. Hesitancy and acceptance of COVID-19 vaccination amidst the second wave of pandemic in India: a general population study. Asia Pac J Public Health. 2022; 34(4):446–449. doi: 10.1177/10105395221077062.
   PubMed Web of Science ®Google Scholar
• Bansal P, Raj A, Sinha RK. Correlates of the COVID-19 vaccine hesitancy among Indians. Asia Pac J Public Health. 2022;34(5):583–585. doi: 10.1177/10105395221077065
   PubMed Web of Science ®Google Scholar
• Samanta S, Banerjee J, Kar SS, et al. Awareness, knowledge and acceptance of COVID-19 vaccine among the people of West Bengal, India: a web-based survey. Vacunas. 2022;23:S46–S55. doi: 10.1016/j.vacun.2022.01.002
   PubMedGoogle Scholar
• Hawlader MDH, Rahman ML, Nazir A, et al. COVID-19 vaccine acceptance in South Asia: a multi-country study. Int J Infect Dis. 2022 [cited 2021 Sep 28];114:1–10.
   PubMed Web of Science ®Google Scholar
• Naqvi S, Saleem S, Naqvi F, et al. Knowledge, attitudes, and practices of pregnant women regarding COVID-19 vaccination in pregnancy in 7 low- and middle-income countries: an observational trial from the global network for women and children’s health research. BJOG. 2022; 129(12):2002–2009. doi: 10.1111/1471-0528.17226.
   PubMed Web of Science ®Google Scholar
• Mathew B, George D, Thomas S, et al. Knowledge, attitude and acceptance of COVID-19 vaccine among general population in South India. J Phar Pract. 2022;15(1):36–39. doi: 10.5530/ijopp.15.1.7
   Google Scholar
• Ganju P, Jayachandran PK, Karunakaran P, et al. P-137: COVID – 19 vaccine uptake in patients with multiple myeloma and AL amyloidosis: a cross-sectional observational study from India. Clin Lymphoma Myeloma Leuk. 2022;22:S110. doi: 10.1016/S2152-2650(22)00467-0
   Web of Science ®Google Scholar
• Higgins JP, Thompson SG Quantifying heterogeneity in a meta-analysis. Stat Med. 2002; 21(11):1539–1558. doi: 10.1002/sim.1186.
   PubMed Web of Science ®Google Scholar
• Sonekar HB, Ponnaiah M Emergence of Coronavirus (COVID-19) outbreak: anthropological and social science perspectives. Disaster Med Public Health Prep. 2020; 14(6):759–761. doi: 10.1017/dmp.2020.203.
   PubMed Web of Science ®Google Scholar
• The economic times: covid vaccination: ‘har ghar dastak’ campaign begins in Delhi. (2021). https://economictimes.indiatimes.com/news/india/covid-vaccination-har-ghar-dastakcampaign-begins-in-delhi/articleshow/87665722.cms
   Google Scholar
• Ministry of Health and family Welfare: Union Health Ministry reviews status and progress under “har ghar dastak” campaign with States/UTs. 2021.https://pib.gov.in/PressReleasePage.aspx?PRID=1777164
   Google Scholar
• Narayan P, Ts SK, Bv MM, et al. Uptake and impact of vaccination against COVID-19 among healthcare workers-evidence from a multicentre study. Am J Infect Control. 2022; 50(3):361–363. doi: 10.1016/j.ajic.2021.10.036.
   PubMed Web of Science ®Google Scholar
• Centre for Disease Control. The importance of COVID-19 vaccination for healthcare personnel. Centers For Disease Control And Prevention; 2021. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/hcp.html.
   Google Scholar
• Government of India. Ministry of Health and family Welfare: covid-19 statistics. COVID-19 Vaccination As On: 19 September 2023, 08: 00 IST (GMT+5: 30). [cited 2023 Sept 19]. Available from: https://www.mohfw.gov.in/
   Google Scholar
• Mathieu E, Ritchie H, Ortiz-Ospina E, et al. A global database of COVID-19 vaccinations. Nat Human Behav. 2021 Jul [cited 2023 19, Sept];5(7):947–953. doi: 10.1038/s41562-021-01122-8
   PubMed Web of Science ®Google Scholar