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Research Article

Awareness, perspectives and practices of antibiotics deprescribing among physicians in Jordan: a cross-sectional study

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Article: 2378484 | Received 08 Apr 2024, Accepted 04 Jul 2024, Published online: 19 Jul 2024

References

  • Adedeji, W. A. (2016). The treasure called antibiotics. Annals of Ibadan Postgraduate Medicine, 14(2), 56–57.
  • Akande-Sholabi, W., Ajilore, C. O., & Ilori, T. (2023). Evaluation of physicians’ knowledge of deprescribing, deprescribing tools and assessment of factors affecting deprescribing process. BMC Primary Care, 24(1), 31. https://doi.org/10.1186/s12875-023-01990-1
  • Al-Taani, G., Al-Azzam, S., Karasneh, R. A., Ababneh, M., Al-Batayneh, O. B., Khader, Y. S., Conway, B. R., & Aldeyab, M. A. (2022). Antibiotic use and resistance: Information sources and application by dentists in Jordan. The Journal of Infection in Developing Countries, 16(10), 1607–1613. https://doi.org/10.3855/jidc.16540
  • Al-Taani, G. M., Al-Azzam, S., Karasneh, R. A., Sadeq, A. S., Mazrouei, N. A., Bond, S. E., Conway, B. R., & Aldeyab, M. A. (2022). Pharmacists’ knowledge, attitudes, behaviors and information sources on antibiotic use and resistance in Jordan. Antibiotics, 11. https://doi.org/10.3390/antibiotics11020175
  • AlRasheed, M. M., Alhawassi, T. M., Alanazi, A., Aloudah, N., Khurshid, F., & Alsultan, M. (2018). Knowledge and willingness of physicians about deprescribing among older patients: A qualitative study. Clinical Intervention in Aging, 13, 1401–1408. https://doi.org/10.2147/CIA.S165588
  • Alsayed, A. R., Darwish El Hajji, F., Al-Najjar, M. A. A., Abazid, H., & Al-Dulaimi, A. (2022). Patterns of antibiotic use, knowledge, and perceptions among different population categories: A comprehensive study based in Arabic countries. Saudi Pharmaceutical Journal, 30(3), 317–328. https://doi.org/10.1016/j.jsps.2022.01.013
  • Álvarez Artero, E., Campo Nuñez, A., Garcia Bravo, M., Cores Calvo, O., Belhassen Garcia, M., & Pardo Lledias, J. (2019). Urinary infection in the elderly. Revisita Clinica Espanola, 219(4), 189–193. https://doi.org/10.1016/j.rce.2018.10.009
  • Aslam, B., Wang, W., Arshad, M. I., Khurshid, M., Muzammil, S., Rasool, M. H., Nisar, M. A., Alvi, R. F., Aslam, M. A., & Qamar, M. U. (2018). Antibiotic resistance: A rundown of a global crisis. Infection and Drug Resistance, 1645–1658. https://doi.org/10.2147/IDR.S173867
  • Bynum, J. P., Barre, L., Reed, C., & Passow, H. (2014). Participation of very old adults in health care decisions. Medical Decision Making, 34(2), 216–230. https://doi.org/10.1177/0272989X13508008
  • Conlon-Bingham, G. M., Aldeyab, M., Scott, M., Kearney, M. P., Farren, D., Gilmore, F., & McElnay, J. (2019). Effects of antibiotic cycling policy on incidence of healthcare-associated MRSA and Clostridioides difficile Infection in secondary healthcare settings. Emerging Infectious Diseases, 25(1), 52–62. https://doi.org/10.3201/eid2501.180111
  • Cosgrove, S. E. (2006). The relationship between antimicrobial resistance and patient outcomes: Mortality, length of hospital stay, and health care costs. Clinical Infectious Diseases, 42(Suppl 2), S82–S89. https://doi.org/10.1086/499406
  • Costelloe, C., Metcalfe, C., Lovering, A., Mant, D., & Hay, A. D. (2010). Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: Systematic review and meta-analysis. BMJ, 340(may18 2), cc2096. https://doi.org/10.1136/bmj.c2096
  • Crisafulli, S., Poluzzi, E., Lunghi, C., Di Francesco, V., Pellizzari, L., Pasina, L., Elli, C., Trotta, F., Cangini, A., Trevisan, C., Zazzara, M. B., Onder, G., & Trifirò, G. (2022). Deprescribing as a strategy for improving safety of medicines in older people: Clinical and regulatory perspective. Frontiers in Drug Safety and Regulation, 2. https://doi.org/10.3389/fdsfr.2022.1011701
  • Doherty, A. J., Boland, P., Reed, J., Clegg, A. J., Stephani, A. M., Williams, N. H., Shaw, B., Hedgecoe, L., Hill, R., & Walker, L. (2020). Barriers and facilitators to deprescribing in primary care: A systematic review. BJGP Open, 4(3), https://doi.org/10.3399/bjgpopen20X101096
  • Doumat, G., Daher, D., Itani, M., Abdouni, L., El Asmar, K., & Assaf, G. (2023). The effect of polypharmacy on healthcare services utilization in older adults with comorbidities: A retrospective cohort study. BMC Primary Care, 24(1), 120. https://doi.org/10.1186/s12875-023-02070-0
  • El-Dahiyat, F., Jairoun, A. A., Al-Hemyari, S. S., Shahwan, M., Hassan, N., Jairoun, S., & Jaber, A. A. S. (2023). Are pharmacists’ knowledge and practice the key to promoting deprescribing of potentially inappropriate medication: A missing link between treatment and outcomes. International Journal of Pharmacy Practice, 31(4), 387–395. https://doi.org/10.1093/ijpp/riad027
  • Formica, D., Sultana, J., Cutroneo, P. M., Lucchesi, S., Angelica, R., Crisafulli, S., Ingrasciotta, Y., Salvo, F., Spina, E., & Trifirò, G. (2018). The economic burden of preventable adverse drug reactions: A systematic review of observational studies. Expert Opinion on Drug Safety, 17(7), 681–695. https://doi.org/10.1080/14740338.2018.1491547
  • Fu, M., Gong, Z., Zhu, Y., Li, C., Zhou, Y., Hu, L., Li, H., Wushouer, H., Guan, X., & Shi, L. (2023). Inappropriate antibiotic prescribing in primary healthcare facilities in China: A nationwide survey, 2017-2019. Clinical Microbiology and Infection, 29(5), 602–609. https://doi.org/10.1016/j.cmi.2022.11.015
  • Gilpin, R., McDade, O. C., & Edwards, C. (2022). Attitudes toward deprescribing for hospital inpatients. Clinical Medicine, 22(1), 58–62. https://doi.org/10.7861/clinmed.2021-0445
  • Gould, K. (2016). Antibiotics: From prehistory to the present day. Journal of Antimicrobial Chemotherapy, 71(3), 572–575. https://doi.org/10.1093/jac/dkv484
  • Gupta, S., Miller, R., Cahill, J. D., Gupta, S., Cahill, J., & Miller, R. (2019). 47C3Barriers to deprescribing: Origins and solutions. In S. Gupta, R. Miller, & J. D. Cahill (Eds.), Deprescribing in Psychiatry (p. 47). Oxford University Press.
  • Hansen, M. P., Scott, A. M., McCullough, A., Thorning, S., Aronson, J. K., Beller, E. M., Glasziou, P. P., Hoffmann, T. C., Clark, J., & Del Mar, C. B. (2019). Adverse events in people taking macrolide antibiotics versus placebo for any indication. Cochrane Database of Systematic Reviews, 2019(1), Cd011825. https://doi.org/10.1002/14651858.CD011825.pub2
  • Jansen, J., Naganathan, V., Carter, S. M., McLachlan, A. J., Nickel, B., Irwig, L., Bonner, C., Doust, J., Colvin, J., Heaney, A., Turner, R., & McCaffery, K. (2016). Too much medicine in older people? Deprescribing through shared decision making. BMJ, 353, i2893. https://doi.org/10.1136/bmj.i2893
  • Karasneh, R. A., Al-Azzam, S. I., Ababneh, M. A., Basheti, I. A., Al-Azzeh, O., Al Sharie, S., Conway, B. R., & Aldeyab, M. A. (2021). Exploring information available to and used by physicians on antibiotic use and antibiotic resistance in Jordan. Antibiotics, 10(8). https://doi.org/10.3390/antibiotics10080963
  • Kua, C. H., Mak, V. S., & Lee, S. W. H. (2019). Perspectives of health professionals towards deprescribing practice in Asian nursing homes: A qualitative interview study. BMJ Open, 9(10), e030106. https://doi.org/10.1136/bmjopen-2019-030106
  • Llewelyn, M. J., Fitzpatrick, J. M., Darwin, E., SarahTonkin, C., Gorton, C., Paul, J., Peto, T. E. A., Yardley, L., Hopkins, S., & Walker, A. S. (2017). The antibiotic course has had its day. BMJ, 358, j3418. https://doi.org/10.1136/bmj.j3418
  • Llor, C., & Bjerrum, L. (2014). Antimicrobial resistance: Risk associated with antibiotic overuse and initiatives to reduce the problem. Therapeutics Advances in Drug Safety, 5(6), 229–241. https://doi.org/10.1177/2042098614554919
  • Llor, C., Cordoba, G., de Oliveira, S. M., Bjerrum, L., & Moragas, A. (2022). Antibiotic deprescribing: Spanish general practitioners’ views on a new strategy to reduce inappropriate use of antibiotics in primary care. European Journal of General Practice, 28(1), 217–223. https://doi.org/10.1080/13814788.2022.2130887
  • Llor, C., Moragas, A., Bayona, C., Cots, J. M., Hernández, S., Calviño, O., Rodríguez, M., & Miravitlles, M. (2022). Efficacy and safety of discontinuing antibiotic treatment for uncomplicated respiratory tract infections when deemed unnecessary. A multicentre, randomized clinical trial in primary care. Clinical Microbiololgy and Infection, 28(2), 241–247. https://doi.org/10.1016/j.cmi.2021.07.035
  • Lukacena, K. M., Keck, J. W., Freeman, P. R., Harrington, N. G., Huffmyer, M. J., & Moga, D. C. (2022). Patients’ attitudes toward deprescribing and their experiences communicating with clinicians and pharmacists. Therpeutic Advances in Drug Safety, 13, 204209862211164. https://doi.org/10.1177/20420986221116465
  • Mahmood, R. K., Gillani, S. W., Alzaabi, M. J., & Gulam, S. M. (2022). Evaluation of inappropriate antibiotic prescribing and management through pharmacist-led antimicrobial stewardship programmes: A meta-analysis of evidence. European Journal of Hospital Pharmacy, 29(1), 2–7. https://doi.org/10.1136/ejhpharm-2021-002914
  • Mohr, K. I. (2016). Current topics in microbiology and immunology of antibiotics research. Current Topics in Microbiololgy and Immunology, 398, 237–272. https://doi.org/10.1007/82_2016_499
  • Nashwan, A. J., Barakat, M., Niaz, F., Tariq, S., Ahmed, S. K., & Tariq Sr, S. (2024). Antimicrobial resistance: Stewardship and one health in the eastern Mediterranean region. Cureus, 16(4).
  • Nathan, C., & Cars, O. (2014). Antibiotic resistance–problems, progress, and prospects. New England Journal of Medicine England Journal of Medicine, 371(19), 1761–1763. https://doi.org/10.1056/NEJMp1408040
  • Norton, J. D., Zeng, C., Bayliss, E. A., Shetterly, S. M., Williams, N., Reeve, E., Wynia, M. K., Green, A. R., Drace, M. L., Gleason, K. S., Sheehan, O. C., & Boyd, C. M. (2023). Ethical aspects of physician decision-making for deprescribing among older adults with dementia. JAMA Network Open, 6(10), e2336728. https://doi.org/10.1001/jamanetworkopen.2023.36728
  • Okeowo, D. A., Zaidi, S. T. R., Fylan, B., & Alldred, D. P. (2023). Barriers and facilitators of implementing proactive deprescribing within primary care: A systematic review. International Journal of Pharmacy Practice, 31(2), 126–152. https://doi.org/10.1093/ijpp/riad001
  • O'Mahony, D., O'Sullivan, D., Byrne, S., O'Connor, M. N., Ryan, C., & Gallagher, P. (2015). STOPP/START criteria for potentially inappropriate prescribing in older people: Version 2. Age and Ageing, 44(2), 213–218. https://doi.org/10.1093/ageing/afu145
  • O'Neill, J. (2016). Tackling drug-resistant infections globally: Final report and recommendations.
  • Page, A. T., Clifford, R. M., Potter, K., Schwartz, D., & Etherton-Beer, C. D. (2016). The feasibility and effect of deprescribing in older adults on mortality and health: A systematic review and meta-analysis. British Journal of Clinical Pharmacology, 82(3), 583–623. https://doi.org/10.1111/bcp.12975
  • Pereira, A., & Veríssimo, M. (2023). Deprescribing in older adults: Time has come. European Geriatric Medicine, 14(1), 1–3. https://doi.org/10.1007/s41999-022-00716-3
  • Read, A. F., & Woods, R. J. (2014). Antibiotic resistance management. Evolution, Medicine, and Public Health, 2014(1), 147. https://doi.org/10.1093/emph/eou024
  • Reeve, E., Thompson, W., & Farrell, B. (2017). Deprescribing: A narrative review of the evidence and practical recommendations for recognizing opportunities and taking action. European Journal of Internal Medicine, 38, 3–11. https://doi.org/10.1016/j.ejim.2016.12.021
  • Rodrigues, T., Roque, A., Falcao, F., Figueiras, A., Herdeiro, A., & T, M. (2013). Understanding physician antibiotic prescribing behaviour: A systematic review of qualitative studies. International Journal of Antimicrobial Agents, 41(3), 203–212. https://doi.org/10.1016/j.ijantimicag.2012.09.003
  • Scott, I., Anderson, K., & Freeman, C. (2017). Review of structured guides for deprescribing. European Journal of Hospital Pharmacy, 24(1), 51–57. https://doi.org/10.1136/ejhpharm-2015-000864
  • Spellberg, B., Bartlett, J. G., & Gilbert, D. N. (2013). The future of antibiotics and resistance. New England Journal of Medicine, 368(4), 299–302. https://doi.org/10.1056/NEJMp1215093
  • Tabachnick, B. G., & Fidell, L. S. (2006). Using multivariate statistic (5th ed.). Allyn and Bacon Inc.
  • Taber, K. S. (2018). The use of Cronbach’s Alpha when developing and reporting research instruments in science education. Research in Science Education, 48(6), 1273–1296. https://doi.org/10.1007/s11165-016-9602-2
  • Tanwar, J., Das, S., Fatima, Z., & Hameed, S. (2014). Multidrug resistance: An emerging crisis. Interdisciplinary Perspectives on Infectious Disease, 2014, 541340. https://doi.org/10.1155/2014/541340
  • Thompson, W., Lundby, C., Graabaek, T., Nielsen, D. S., Ryg, J., Søndergaard, J., & Pottegård, A. (2019). Tools for deprescribing in frail older persons and those with limited life expectancy: A systematic review. Journal of the American Geriatrics Society, 67(1), 172–180. https://doi.org/10.1111/jgs.15616
  • Urbiztondo, I., de Oliveira, S. M., Hernández-Flores, N., Caballero, L., Suarez, M. A., Bjerrum, L., & Cordoba, G. (2018). General practitioners’ views on the acceptability and applicability of using quality indicators as an intervention to reduce unnecessary prescription of antibiotics in four South American countries. Antibiotics (Basel), 7(3), https://doi.org/10.3390/antibiotics7030057
  • Van Boeckel, T. P., Brower, C., Gilbert, M., Grenfell, B. T., Levin, S. A., Robinson, T. P., Teillant, A., & Laxminarayan, R. (2015). Global trends in antimicrobial use in food animals. Proceeding of the National Academy of Sciences, 112(18), 5649–5654. https://doi.org/10.1073/pnas.1503141112
  • Ventola, C. L. (2015). The antibiotic resistance crisis: Part 2: Management strategies and new agents. Pharmacy and Therapeutics, 40(5), 344–352. https://www.ncbi.nlm.nih.gov/pubmed/25987823
  • Woodford, H. J., & Fisher, J. (2019). New horizons in deprescribing for older people. Age and Ageing, 48(6), 768–775. https://doi.org/10.1093/ageing/afz109
  • Wu, H., Kouladjian, O., Donnell, L., Fujita, K., Masnoon, N., & Hilmer, S. N. (2021). Deprescribing in the older patient: A narrative review of challenges and solutions. International Journal of General Medicine, 14, 3793–3807. https://doi.org/10.2147/IJGM.S253177