An overview of fixed-dose combinations of antihypertensive drugs in South Africa

References

• Sever PS, Messerli FH. Hypertension management 2011: optimal combination therapy. Eur Heart J. 2011;32:2499–506.10.1093/eurheartj/ehr177
   PubMed Web of Science ®Google Scholar
• James AP, Oparil S, Carter BL, et al, and the National High Blood Pressure Education Program Coordinating Committee. Eight report of the joint national committee on prevention, detection, evaluation and treatment of high blood pressure. JAMA; 2013.
   Google Scholar
• Gradman AH, Basile JN, Carter BL, et al. Combination therapy in hypertension. J Am Soc Hypertens. 2010;4(1):42–50.10.1016/j.jash.2010.02.005
   PubMed Web of Science ®Google Scholar
• Peltzer K, Phaswana-Mafuya N. Hypertension and associated factors in older adults in South Africa. Cardiovasc J Afr. 2013;24(3):67–72.
   PubMed Web of Science ®Google Scholar
• Yang W, Chang J, Kahler KH, et al. Evaluation of compliance and health care utilization in patients treated with single pill vs. free combination antihypertensives. Curr Med Res Opin. 2010;26(9):2065–76.10.1185/03007995.2010.494462
   PubMed Web of Science ®Google Scholar
• Basile J, Neutel J. Overcoming clinical inertia to achieve blood pressure goals: the role of fixed-dose combination therapy. Ther Adv Cardiovasc Dis. 2009;4:119–127.
   PubMedGoogle Scholar
• Neutel JM. Prescribing patterns in hypertension: emerging role of fixed dose combinations for attaining BP goals in hypertensive patients. Curr Med Res Opin. 2008;24(8):2389–401.10.1185/03007990802262457
   PubMed Web of Science ®Google Scholar
• Mazzaglia G, Ambrosioni E, Alacqua M, et al. Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients. Hypertens J Am Heart Assoc. 2009;120:1598–605.
   Google Scholar
• Zeng F, Patel BV, Andrews L, et al. Adherence and persistence of single-pill ARB/CCB combination therapy compared to multiple-pill ARB/CCB regimens. Curr Med Res Opin. 2010;26(12):2877–87.10.1185/03007995.2010.534129
   PubMed Web of Science ®Google Scholar
• Kalra S, Kalra B, Agrawal N. Combination therapy in hypertension: an update. Diabetol Metab Syndrome. 2010;2:44. doi: 10.1186/1758-5996-2-44. 10.1186/1758-5996-2-44
   PubMed Web of Science ®Google Scholar
• Gupta AK, Arshad S, Poulter NR. Compliance, safety and effectiveness of fixed-dose combinations of antihypertensive agents; a meta-analysis. Hypertension. 2010;55: 399–407.10.1161/HYPERTENSIONAHA.109.139816
   PubMed Web of Science ®Google Scholar
• Williams B. The year in hypertension. J Am Coll Cardiol. 2010;55(1): 65–73.
   Web of Science ®Google Scholar
• Ferrario CM, Panjabi S, Buzinec P, et al. Clinical and economic outcomes associated with amlodipine/renin-angiotensin system blocker combinations. Ther Adv Cardiovasc Dis. 2013;7:27–39.10.1177/1753944712470979
   PubMedGoogle Scholar
• Kjeldsen SE, Messerli FH, Chiang CE, et al. Are fixed-dose combination antihypertensives suitable as first-line therapy? Curr Med Res Opin. 2012;28(10):1685–97.10.1185/03007995.2012.729505
   PubMed Web of Science ®Google Scholar
• Malekzadeh F, Marshall T, Pourshams A, et al. Apilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy (‘poly-pill’) on cardiovascular risk factors. Int J Clin Pract. 2010;64:1171–3.
   PubMed Web of Science ®Google Scholar
• Schmieder RE. The role of fixed-dose combination therapy with drugs that target the renin-angiotensin system in the hypertension paradigm. Clin Exp Hypertens. 2010;32:35–42.10.3109/10641960902960532
   PubMed Web of Science ®Google Scholar
• Feldman RD, Zou GY, Vandervoort MK, et al. A simplified approach to the treatment of uncomplicated hypertension: a cluster randomized, controlled trial. Hypertens J Am Heart Assoc. 2009;53:646–53.
   Google Scholar
• Bakris GL, Pantelis AS, Weir MR, et al., for the ACCOMPLISH Trial investigators. Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial. Lancet. 2010; 375:1173–81.10.1016/S0140-6736(09)62100-0
   PubMed Web of Science ®Google Scholar
• Düsing R. Optimizing blood pressure control through the use of fixed combinations. Vasc Health Risk Manage. 2010;6:321–5.10.2147/VHRM
   PubMedGoogle Scholar
• Black HR. Triple fixed-dose combination therapy: back to the past. Hypertension. 2009;54: 19–22.10.1161/HYPERTENSIONAHA.109.132688
   PubMed Web of Science ®Google Scholar
• Poulter NR, Dobson JE, Server PS, et al. Baseline heart rate, antihypertensive treatment, and prevention of cardiovascular outcomes in ASCOT (Anglo-Scandinavian cardiac outcomes trial). J Am Coll Cardiol. 2009;54:1154–61.10.1016/j.jacc.2009.04.087
   PubMed Web of Science ®Google Scholar
• Schellack G, editor. Pharmacology in clinical practice: application made easy for nurses and allied health professionals. 2nd ed. Claremont: Juta and Company; 2010.
   Google Scholar
• Snyman JR, editor. MIMS (monthly index of medical specialities). Magazine Publisher Association of South Africa; 2014; 53(11).
   Google Scholar