Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction

References

• Thorburn A. Apoptosis and autophagy: regulatory connections between two supposedly different processes. Apoptosis 2008; 13:1-9; PMID:17990121; http://dx.doi.org/10.1007/s10495-007-0154-9
   PubMed Web of Science ®Google Scholar
• Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X, Stolz DB, Shao ZM, Yin XM. Differential effects of endoplasmic reticulum stress induced autophagy on cell survival. J Biol Chem 2007; 282(7):4702-10; PMID:17135238; http://dx.doi.org/10.1074/jbc.M609267200
   PubMed Web of Science ®Google Scholar
• Nikoletopoulou V, Markaki M, Palikaras K, Tavernarakis N. Crosstalk between apoptosis, necrosis and autophagy. BiochimBiophysActa 2013; 1833(12):3448-59
   PubMed Web of Science ®Google Scholar
• Wang W, Zhou J, Shi J, Zhang Y, Liu S, Liu Y, Zheng D. Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis. J Virol 2014; 88(5):2786-98; PMID:24352466; http://dx.doi.org/10.1128/JVI.03025-13
   PubMed Web of Science ®Google Scholar
• Gannagé M, Dormann D, Albrecht R, Dengjel J, Torossi T, Rämer PC, Lee M, Strowig T, Arrey F, Conenello G, et al. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 2009; 6(4):367-80; http://dx.doi.org/10.1016/j.chom.2009.09.005
   PubMed Web of Science ®Google Scholar
• Martyniszyn L, Szulc L, Boratyńska A, Niemiałtowski MG. Beclin 1 is involved in regulation of apoptosis and autophagy during replication of ectromelia virus in permissiveL929 cells. Arch ImmunolTherExp (Warsz). 2011; 59(6):463-71; http://dx.doi.org/10.1007/s00005-011-0149-7
   PubMed Web of Science ®Google Scholar
• Espert L, Denizot M, Grimaldi M, Robert-Hebmann V, Gay B, Varbanov M, Codogno P, Biard-Piechaczyk M. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest 2006; 116(8):2161-72; PMID:16886061; http://dx.doi.org/10.1172/JCI26185
   PubMed Web of Science ®Google Scholar
• Sun MX, Huang L, Wang R, Yu YL, Li C, Li PP, Hu XC, Hao HP, Ishag HA, Mao X. Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication. Autophagy 2012; 8(10):1434-47; PMID:22739997; http://dx.doi.org/10.4161/auto.21159
   PubMed Web of Science ®Google Scholar
• Costers S, Lefebvre DJ, Delputte PL, Nauwynck HJ. Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages. Arch Virol 2008; 153(8):1453-65; PMID:18563285; http://dx.doi.org/10.1007/s00705-008-0135-5
   PubMed Web of Science ®Google Scholar
• Tanida I, Ueno T, Kominami E. LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004; 36(12):2503-18; PMID:15325588; http://dx.doi.org/10.1016/j.biocel.2004.05.009
   PubMed Web of Science ®Google Scholar
• Komatsu M, Kageyama S, Ichimura Y. p62/SQSTM1/A170: physiology and pathology. Pharmacol Res. 2012; 66(6):457-62; PMID:22841931; http://dx.doi.org/10.1016/j.phrs.2012.07.004
   PubMed Web of Science ®Google Scholar
• Tang H, Da L, Mao Y, Li Y, Li D, Xu Z, Li F, Wang Y, Tiollais P, Li T, Zhao M. Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression. Hepatology 2009; 49(1):60-71; PMID:19065679; http://dx.doi.org/10.1002/hep.22581
   PubMed Web of Science ®Google Scholar
• Shrivastava S, Bhanja Chowdhury J, Steele R, Ray R, Ray RB. Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling. J Virol 2012; 86(16):8705-12; PMID:22674982; http://dx.doi.org/10.1128/JVI.00616-12
   PubMed Web of Science ®Google Scholar
• Bouley SJ, Maginnis MS, Derdowski A, Gee GV, O'Hara BA, Nelson CD, Bara AM, Atwood WJ, Dugan AS. Host cell autophagy promotes BK virus infection.Virology 2014; 456-457:87-95; PMID:24889228; http://dx.doi.org/10.1016/j.virol.2014.03.009
   PubMed Web of Science ®Google Scholar
• Kim H, Choi H, Lee SK. Epstein-Barr virus miR-BART20-5p regulates cell proliferation and apoptosis by targeting BAD. Cancer Lett 2005; 356(2 Pt B):733-42
   Google Scholar
• Olavarría VH, Recabarren P, Fredericksen F, Villalba M, Yáñez A. ISAV infection promotes apoptosis of SHK-1 cells through a ROS/p38 MAPK/Bad signaling pathway. MolImmunol 2014; 64(1):1-8
   Google Scholar
• Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, Tasdemir E, Pierron G, Troulinaki K, Tavernarakis N, et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 2007; 26: 2527-2539; PMID:17446862; http://dx.doi.org/10.1038/sj.emboj.7601689
   PubMed Web of Science ®Google Scholar
• Sinha S, Levine B. The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene 2008; 27 Suppl 1:S137-48; PMID:19641499; http://dx.doi.org/10.1038/onc.2009.51
   PubMed Web of Science ®Google Scholar
• Zhou Z, Jiang X, Liu D, Fan Z, Hu X, Yan J, Wang M, Gao GF. Autophagy is involved in influenza A virus replication. Autophagy 2009; 5(3):321-8; PMID:19066474; http://dx.doi.org/10.4161/auto.5.3.7406
   PubMed Web of Science ®Google Scholar
• Zhirnov OP, Klenk HD. Influenza A virus proteins NS1 and hemagglutinin along with M2 are involved in stimulation of autophagy ininfected cells. J Virol 2013; 87(24):13107-14; PMID:24027311; http://dx.doi.org/10.1128/JVI.02148-13
   PubMed Web of Science ®Google Scholar
• Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, Basta S, O'Neill R, Schickli J, Palese P, Henklein P, Bennink JR, Yewdell JW. A novel influenza A virus mitochondrial protein that induces cell death. Nat Med 2001; 7(12):1306-12; PMID:11726970; http://dx.doi.org/10.1038/nm1201-1306
   PubMed Web of Science ®Google Scholar
• Zhirnov OP, Konakova TE, Wolff T, Klenk HD. NS1 protein of influenza A virus down-regulates apoptosis. J Virol 2002; 76(4):1617-25; PMID:11799156; http://dx.doi.org/10.1128/JVI.76.4.1617-1625.2002
   PubMed Web of Science ®Google Scholar
• Gannagé M, Dormann D, Albrecht R, Dengjel J, Torossi T, Rämer PC, Lee M, Strowig T, Arrey F, Conenello G, et al. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 2009; 6(4):367-80; http://dx.doi.org/10.1016/j.chom.2009.09.005
   PubMed Web of Science ®Google Scholar
• Zamarin D, García-Sastre A, Xiao X, Wang R, Palese P. Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoSPathog 2005; 1(1):e4
   Web of Science ®Google Scholar
• Cottam EM, Whelband MC, Wileman T. Coronavirus NSP6 restricts autophagosomeexpansion Autophagy 2014; 10(8):1426-41; PMID:24991833; http://dx.doi.org/10.4161/auto.29309
   PubMed Web of Science ®Google Scholar
• Lee SM, Kleiboeker SB. Porcine reproductive and respiratory syndrome virus induces apoptosis through a mitochondria-mediated pathway. Virology 2007; 365(2):419-34; PMID:17488647; http://dx.doi.org/10.1016/j.virol.2007.04.001
   PubMed Web of Science ®Google Scholar
• Chen Q, Fang L, Wang D, Wang S, Li P, Li M, Luo R, Chen H, Xiao S. Induction of autophagy enhances porcine reproductive and respiratory syndrome virus replication. Virus Res 2012; 163(2):650-5; PMID:22119900; http://dx.doi.org/10.1016/j.virusres.2011.11.008
   PubMed Web of Science ®Google Scholar
• Pujhari S, Baig TT, Zakhartchouk AN. Potential role of porcine reproductive and respiratory syndrome virus structural protein GP2 in apoptosisinhibition. Biomed Res Int 2014; 2014:160505; PMID:24511529; http://dx.doi.org/10.1155/2014/160505
   PubMed Web of Science ®Google Scholar
• Danial NN. BAD: undertaker by night, candyman by day. Oncogene 2008; 27Suppl 1:S53-70; PMID:19641507; http://dx.doi.org/10.1038/onc.2009.44
   PubMedGoogle Scholar
• Chiang CW, Kanies C, Kim KW, Fang WB, Parkhurst C, Xie M, Henry T, Yang E. Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. Mol Cell Biol 2003; 23(18):6350-62; PMID:12944463; http://dx.doi.org/10.1128/MCB.23.18.6350-6362.2003
   PubMed Web of Science ®Google Scholar
• Scheid MP, Schubert KM, Duronio V. Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase. J Biol Chem 1999; 274(43):31108-13; PMID:10521512; http://dx.doi.org/10.1074/jbc.274.43.31108
   PubMed Web of Science ®Google Scholar
• Hayakawa J, Ohmichi M, Kurachi H, Kanda Y, Hisamoto K, Nishio Y, Adachi K, Tasaka K, Kanzaki T, Murata Y. Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin. Cancer Res 2000; 60(21):5988-94; PMID:11085518
   PubMed Web of Science ®Google Scholar
• Yan J, Xiang J, Lin Y, Ma J, Zhang J, Zhang H, Sun J, Danial NN, Liu J, Lin A. Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation. Cell 2013; 152(1-2):304-15; PMID:23332762; http://dx.doi.org/10.1016/j.cell.2012.12.021
   PubMed Web of Science ®Google Scholar
• Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, Tasdemir E, Pierron G, Troulinaki K, Tavernarakis N, et al. Functional and physical interaction between Bcl-X (L) and a BH3-like domain in Beclin-1. EMBO J 2007; 26(10):2527-39; PMID:17446862; http://dx.doi.org/10.1038/sj.emboj.7601689
   PubMed Web of Science ®Google Scholar
• Liu Y, Sun SY, Owonikoko TK, Sica GL, Curran WJ, Khuri FR, Deng X. Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells. Mol Cancer Ther 2012; 11(1):45-56; PMID:22057915; http://dx.doi.org/10.1158/1535-7163.MCT-11-0578
   PubMed Web of Science ®Google Scholar
• Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 1996; 87(4):619-28; PMID:8929531; http://dx.doi.org/10.1016/S0092-8674(00)81382-3
   PubMed Web of Science ®Google Scholar
• Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18(4):571-80; PMID:21311563; http://dx.doi.org/10.1038/cdd.2010.191
   PubMed Web of Science ®Google Scholar
• Martyniszyn L, Szulc L, Boratyńska A, Niemiałtowski MG. Beclin 1 is involved in regulation of apoptosis and autophagy during replication of ectromelia virus in permissive L929 cells. Arch ImmunolTherExp (Warsz) 2011; 59(6):463-71; http://dx.doi.org/10.1007/s00005-011-0149-7
   PubMed Web of Science ®Google Scholar
• Xu X, Fu Y, Tong J, Fan S, Xu K, Sun H, Liang Y, Yan C, Yuan Z, Ge Y. MicroRNA-216b/Beclin 1 axis regulates autophagy and apoptosis in human Tenon's capsule fibroblasts upon hydroxycamptothecin exposure. Exp Eye Res 2014; 123:43-55; PMID:24681041; http://dx.doi.org/10.1016/j.exer.2014.03.008
   PubMed Web of Science ®Google Scholar
• Luo S, Rubinsztein DC. Apoptosis blocks Beclin 1 dependent autophagosome synthesis: an effect rescued by Bcl-xL. Cell Death Differ 2010; 17(2):268-77; PMID:19713971; http://dx.doi.org/10.1038/cdd.2009.121
   PubMed Web of Science ®Google Scholar
• Lindqvist LM, Vaux DL. BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy. Autophagy 2014; 10(8):1474-5; PMID:24991825; http://dx.doi.org/10.4161/auto.29639
   PubMed Web of Science ®Google Scholar
• Lindqvist LM, Heinlein M, Huang DC, Vaux DL. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak. Proc Natl AcadSci U S A 2014; 111(23):8512-7; http://dx.doi.org/10.1073/pnas.1406425111
   PubMed Web of Science ®Google Scholar
• Zhu L, Yang S, Tong W, Zhu J, Yu H, Zhou Y, Morrison RB, Tong G. Control of the PI3K/Akt pathway by porcine reproductive and respiratory syndrome virus. Arch Virol 2013; 158(6):1227-34; PMID:23381397; http://dx.doi.org/10.1007/s00705-013-1620-z
   PubMed Web of Science ®Google Scholar
• Lee YJ, Lee C. Porcine reproductive and respiratory syndrome virus replication is suppressed by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway. Virus Res 2010; 152(1-2):50-8; PMID:20540975; http://dx.doi.org/10.1016/j.virusres.2010.06.002
   PubMed Web of Science ®Google Scholar