1,271
Views
19
CrossRef citations to date
0
Altmetric
Research Paper

Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense

ORCID Icon, , , , , , ORCID Icon, , ORCID Icon, ORCID Icon, & ORCID Icon show all
Pages 810-820 | Received 12 Jul 2016, Accepted 21 Oct 2016, Published online: 02 Dec 2016

References

  • Chastre J, Fagon J-Y. Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002; 165:867-903; PMID:11934711; http://dx.doi.org/10.1164/ajrccm.165.7.2105078
  • Bekaert M, Timsit J-F, Vansteelandt S, Depuydt P, Vésin A, Garrouste-Orgeas M, Decruyenaere J, Clec'h C, Azoulay E, Benoit D, et al. Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Respir Crit Care Med 2011; 184:1133-9; PMID:21852541; http://dx.doi.org/10.1164/rccm.201105-0867OC
  • American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171:388-416; PMID:15699079; http://dx.doi.org/10.1164/rccm.200405-644ST
  • Nseir S, Di Pompeo C, Diarra M, Brisson H, Tissier S, Boulo M, Durocher A. Relationship between immunosuppression and intensive care unit-acquired multidrug-resistant bacteria: a case-control study. Crit Care Med 2007; 35:1318-23; PMID:17414081; http://dx.doi.org/10.1097/01.CCM.0000261885.50604.20
  • Sonnenberg GF, Fouser LA, Artis D. Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat Immunol 2011; 12:383-90; PMID:21502992; http://dx.doi.org/10.1038/ni.2025
  • Sabat R, Ouyang W, Wolk K. Therapeutic opportunities of the IL-22-IL-22R1 system. Nat Rev Drug Discov 2014; 13:21-38; PMID:24378801; http://dx.doi.org/10.1038/nrd4176
  • Shu Q, Shi Z, Zhao Z, Chen Z, Yao H, Chen Q, Hoeft A, Stuber F, Fang X. Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats. Shock Augusta Ga 2006; 26:365-71; http://dx.doi.org/10.1097/01.shk.0000224722.65929.58
  • Kumar A, Zhang J, Yu F-SX. Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells. Microbes Infect Inst Pasteur 2006; 8:380-9; http://dx.doi.org/10.1016/j.micinf.2005.07.006
  • Mijares LA, Wangdi T, Sokol C, Homer R, Medzhitov R, Kazmierczak BI. Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway. J Immunol Baltim Md 1950 2011; 186:7080-8
  • Ramphal R, Balloy V, Huerre M, Si-Tahar M, Chignard M. TLRs 2 and 4 are not involved in hypersusceptibility to acute Pseudomonas aeruginosa lung infections. J Immunol Baltim Md 1950 2005; 175:3927-34
  • Sadikot RT, Blackwell TS, Christman JW, Prince AS. Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med 2005; 171:1209-23; PMID:15695491; http://dx.doi.org/10.1164/rccm.200408-1044SO
  • Bleves S, Viarre V, Salacha R, Michel GPF, Filloux A, Voulhoux R. Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons. Int J Med Microbiol IJMM 2010; 300:534-43; PMID:20947426; http://dx.doi.org/10.1016/j.ijmm.2010.08.005
  • Beaufort N, Corvazier E, Mlanaoindrou S, de Bentzmann S, Pidard D. Disruption of the endothelial barrier by proteases from the bacterial pathogen Pseudomonas aeruginosa: implication of matrilysis and receptor cleavage. PloS One 2013; 8:e75708; PMID:24069438; http://dx.doi.org/10.1371/journal.pone.0075708
  • Pernet E, Guillemot L, Burgel P-R, Martin C, Lambeau G, Sermet-Gaudelus I, Sands D, Leduc D, Morand PC, Jeammet L, et al. Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity. Nat Commun 2014; 5:5105; PMID:25290234; http://dx.doi.org/10.1038/ncomms6105
  • Mear JB, Gosset P, Kipnis E, Faure E, Dessein R, Jawhara S, Fradin C, Faure K, Poulain D, Sendid B, et al. Candida albicans airway exposure primes the lung innate immune response against Pseudomonas aeruginosa infection through innate lymphoid cell recruitment and interleukin-22-associated mucosal response. Infect Immun 2014; 82:306-15; PMID:24166952; http://dx.doi.org/10.1128/IAI.01085-13
  • Jyot J, Balloy V, Jouvion G, Verma A, Touqui L, Huerre M, Chignard M, Ramphal R. Type II secretion system of Pseudomonas aeruginosa: in vivo evidence of a significant role in death due to lung infection. J Infect Dis 2011; 203:1369-77; PMID:21502078; http://dx.doi.org/10.1093/infdis/jir045
  • Golovkine G, Faudry E, Bouillot S, Voulhoux R, Attrée I, Huber P. VE-cadherin cleavage by LasB protease from Pseudomonas aeruginosa facilitates type III secretion system toxicity in endothelial cells. PLoS Pathog 2014; 10:e1003939; PMID:24626230; http://dx.doi.org/10.1371/journal.ppat.1003939
  • Leduc D, Beaufort N, de Bentzmann S, Rousselle J-C, Namane A, Chignard M, Pidard D. The Pseudomonas aeruginosa LasB metalloproteinase regulates the human urokinase-type plasminogen activator receptor through domain-specific endoproteolysis. Infect Immun 2007; 75:3848-58; PMID:17517866; http://dx.doi.org/10.1128/IAI.00015-07
  • O'Callaghan RJ, Engel LS, Hobden JA, Callegan MC, Green LC, Hill JM. Pseudomonas keratitis. The role of an uncharacterized exoprotein, protease IV, in corneal virulence. Invest Ophthalmol Vis Sci 1996; 37:534-43; PMID:Can't
  • Engel LS, Hill JM, Moreau JM, Green LC, Hobden JA, O'Callaghan RJ. Pseudomonas aeruginosa protease IV produces corneal damage and contributes to bacterial virulence. Invest Ophthalmol Vis Sci 1998; 39:662-5; PMID:9501882
  • Engel LS, Hill JM, Caballero AR, Green LC, O'Callaghan RJ. Protease IV, a unique extracellular protease and virulence factor from Pseudomonas aeruginosa. J Biol Chem 1998; 273:16792-7; PMID:9642237; http://dx.doi.org/10.1074/jbc.273.27.16792
  • Smith L, Rose B, Tingpej P, Zhu H, Conibear T, Manos J, Bye P, Elkins M, Willcox M, Bell S, et al. Protease IV production in Pseudomonas aeruginosa from the lungs of adults with cystic fibrosis. J Med Microbiol 2006; 55:1641-4; PMID:17108265; http://dx.doi.org/10.1099/jmm.0.46845-0
  • Upritchard HG, Cordwell SJ, Lamont IL. Immunoproteomics to examine cystic fibrosis host interactions with extracellular Pseudomonas aeruginosa proteins. Infect Immun 2008; 76:4624-32; PMID:18663005; http://dx.doi.org/10.1128/IAI.01707-07
  • Lejeune D, Dumoutier L, Constantinescu S, Kruijer W, Schuringa JJ, Renauld J-C. Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10. J Biol Chem 2002; 277:33676-82; PMID:12087100; http://dx.doi.org/10.1074/jbc.M204204200
  • Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity 2004; 21:241-54; PMID:15308104; http://dx.doi.org/10.1016/j.immuni.2004.07.007
  • Wolk K, Witte E, Wallace E, Döcke W-D, Kunz S, Asadullah K, Volk H-D, Sterry W, Sabat R. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006; 36:1309-23; PMID:16619290; http://dx.doi.org/10.1002/eji.200535503
  • Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Q, Abbas AR, Modrusan Z, Ghilardi N, de Sauvage FJ, et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 2008; 14:282-9; PMID:18264109; http://dx.doi.org/10.1038/nm1720
  • Aujla SJ, Chan YR, Zheng M, Fei M, Askew DJ, Pociask DA, Reinhart TA, McAllister F, Edeal J, Gaus K, et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med 2008; 14:275-81; PMID:18264110; http://dx.doi.org/10.1038/nm1710
  • Greene CM, McElvaney NG. Proteases and antiproteases in chronic neutrophilic lung disease – relevance to drug discovery. Br J Pharmacol 2009; 158:1048-58; PMID:19845686; http://dx.doi.org/10.1111/j.1476-5381.2009.00448.x
  • Craven DE, Hudcova J, Craven KA, Scopa C, Lei Y. Antibiotic treatment of ventilator-associated tracheobronchitis: to treat or not to treat? Curr Opin Crit Care 2014; 20:532-41; PMID:25051351; http://dx.doi.org/10.1097/MCC.0000000000000130
  • Nseir S, Martin-Loeches I, Makris D, Jaillette E, Karvouniaris M, Valles J, Zakynthinos E, Artigas A. Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia. Crit Care Lond Engl 2014; 18:R129; http://dx.doi.org/10.1186/cc13940
  • Craven DE. Ventilator-associated tracheobronchitis (VAT): questions, answers, and a new paradigm? Crit Care Lond Engl 2008; 12:157; http://dx.doi.org/10.1186/cc6912
  • Pham CTN. Neutrophil serine proteases: specific regulators of inflammation. Nat Rev Immunol 2006; 6:541-50; PMID:16799473; http://dx.doi.org/10.1038/nri1841
  • Malloy JL, Veldhuizen RAW, Thibodeaux BA, O'Callaghan RJ, Wright JR. Pseudomonas aeruginosa protease IV degrades surfactant proteins and inhibits surfactant host defense and biophysical functions. Am J Physiol Lung Cell Mol Physiol 2005; 288:L409-418; PMID:15516485; http://dx.doi.org/10.1152/ajplung.00322.2004
  • Rutz S, Eidenschenk C, Ouyang W. IL-22, not simply a Th17 cytokine. Immunol Rev 2013; 252:116-32; PMID:23405899; http://dx.doi.org/10.1111/imr.12027
  • Nseir S, Povoa P, Salluh J, Rodriguez A, Martin-Loeches I. Is there a continuum between ventilator-associated tracheobronchitis and ventilator-associated pneumonia? Intensive Care Med 2016; 42:1190-2; PMID:27080532
  • Barbier F, Lisboa T, Nseir S. Understanding why resistant bacteria are associated with higher mortality in ICU patients. Intensive Care Med 2015; PMID:26564210 [epub ahead of print]
  • Tang A, Marquart ME, Fratkin JD, McCormick CC, Caballero AR, Gatlin HP, O'Callaghan RJ. Properties of PASP: a Pseudomonas protease capable of mediating corneal erosions. Invest Ophthalmol Vis Sci 2009; 50:3794-801; PMID:19255155; http://dx.doi.org/10.1167/iovs.08-3107
  • Guillon A, Jouan Y, Brea D, Gueugnon F, Dalloneau E, Baranek T, Henry C, Morello E, Renauld J-C, Pichavant M, et al. Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence. Eur Respir J 2015; 46:771-82; PMID:26250498; http://dx.doi.org/10.1183/09031936.00215114
  • Guillon A, Gueugnon F, Mavridis K, Dalloneau E, Jouan Y, Diot P, Heuzé-Vourc'h N, Courty Y, Si-Tahar M. Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis. Eur Respir J 2016; 47:1277-80; PMID:26846835; http://dx.doi.org/10.1183/13993003.01580-2015
  • Guarino C, Legowska M, Epinette C, Kellenberger C, Dallet-Choisy S, Sieńczyk M, Gabant G, Cadene M, Zoidakis J, Vlahou A, et al. New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases. J Biol Chem 2014; 289:31777-91; PMID:25288799; http://dx.doi.org/10.1074/jbc.M114.591339
  • Zani M-L, Nobar SM, Lacour SA, Lemoine S, Boudier C, Bieth JG, Moreau T. Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris. Eur J Biochem FEBS 2004; 271:2370-8; http://dx.doi.org/10.1111/j.1432-1033.2004.04156.x
  • Hoang TT, Karkhoff-Schweizer RR, Kutchma AJ, Schweizer HP. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 1998; 212:77-86; PMID:9661666; http://dx.doi.org/10.1016/S0378-1119(98)00130-9
  • Caballero AR, Moreau JM, Engel LS, Marquart ME, Hill JM, O'Callaghan RJ. Pseudomonas aeruginosa protease IV enzyme assays and comparison to other Pseudomonas proteases. Anal Biochem 2001; 290:330-7; PMID:11237336; http://dx.doi.org/10.1006/abio.2001.4999
  • Kalupov T, Brillard-Bourdet M, Dadé S, Serrano H, Wartelle J, Guyot N, Juliano L, Moreau T, Belaaouaj A, Gauthier F. Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases. J Biol Chem 2009; 284:34084-91; PMID:19833730; http://dx.doi.org/10.1074/jbc.M109.042903
  • Palmer LB, Smaldone GC, Simon SR, O'Riordan TG, Cuccia A. Aerosolized antibiotics in mechanically ventilated patients: delivery and response. Crit Care Med 1998; 26:31-9; PMID:9428540; http://dx.doi.org/10.1097/00003246-199801000-00013

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.