Non-encapsulated Streptococcus pneumoniae, vaccination as a measure to interfere with horizontal gene transfer

References

• Marks LR, Reddinger RM, Hakansson AP. High levels of genetic recombination during nasopharyngeal carriage and biofilm formation in Streptococcus pneumoniae. MBio 2012; 3:pii: e00200-12; PMID:23015736; http://dx.doi.org/10.1128/mBio.00200-12
   PubMed Web of Science ®Google Scholar
• Geno KA, Gilbert GL, Song JY, Skovsted IC, Klugman KP, Jones C, Konradsen HB, Nahm MH. Pneumococcal capsules and their types: past, present, and future. Clin Microbiol Rev 2015; 28:871-99; PMID:26085553; http://dx.doi.org/10.1128/CMR.00024-15
   PubMed Web of Science ®Google Scholar
• Nelson AL, Roche AM, Gould JM, Chim K, Ratner AJ, Weiser JN. Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance. Infect Immun 2007; 75:83-90; PMID:17088346; http://dx.doi.org/10.1128/IAI.01475-06
   PubMed Web of Science ®Google Scholar
• Park IH, Kim KH, Andrade AL, Briles DE, McDaniel LS, Nahm MH. Nontypeable pneumococci can be divided into multiple cps types, including one type expressing the novel gene pspK. MBio 2012; 3:pii: e00035-12; http://dx.doi.org/10.1128/mBio.00035-12
   PubMed Web of Science ®Google Scholar
• Keller LE, Robinson DA, McDaniel LS. Nonencapsulated Streptococcus pneumoniae: Emergence and Pathogenesis. MBio 2016; 7:e01792; PMID:27006456; http://dx.doi.org/10.1128/mBio.01792-15
   PubMed Web of Science ®Google Scholar
• Sa-Leao R, Nunes S, Brito-Avo A, Frazao N, Simoes AS, Crisostomo MI, Paulo AC, Saldanha J, Santos-Sanches I, de Lencastre H. Changes in pneumococcal serotypes and antibiotypes carried by vaccinated and unvaccinated day-care centre attendees in Portugal, a country with widespread use of the seven-valent pneumococcal conjugate vaccine. Clin Microbiol Infect 2009; 15:1002-7; PMID:19392883; http://dx.doi.org/10.1111/j.1469-0691.2009.02775.x
   PubMed Web of Science ®Google Scholar
• Sulikowska A, Grzesiowski P, Sadowy E, Fiett J, Hryniewicz W. Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolated from the nasopharynges of asymptomatic children and molecular analysis of S. pneumoniae and H. influenzae strain replacement in the nasopharynx. J Clin Microbiol 2004; 42:3942-9; PMID:15364973; http://dx.doi.org/10.1128/JCM.42.9.3942-3949.2004
   PubMed Web of Science ®Google Scholar
• Chewapreecha C, Harris SR, Croucher NJ, Turner C, Marttinen P, Cheng L, Pessia A, Aanensen DM, Mather AE, Page AJ, et al. Dense genomic sampling identifies highways of pneumococcal recombination. Nat Genet 2014; 46:305-9; PMID:24509479; http://dx.doi.org/10.1038/ng.2895
   PubMed Web of Science ®Google Scholar
• Andam CP, Hanage WP. Mechanisms of genome evolution of Streptococcus. Infect Genet Evol 2015; 33:334-42; PMID:25461843; http://dx.doi.org/10.1016/j.meegid.2014.11.007
   PubMed Web of Science ®Google Scholar
• Ravin AW. Reciprocal capsular transformations of pneumococci. J Bacteriol 1959; 77:296-309; PMID:13641188
   PubMed Web of Science ®Google Scholar
• Jang AY, Seo HS, Lin S, Chung GH, Kim HW, Lim S, Zhao L, Park IH, Lim JH, Kim KH. Molecular characterization of pneumococcal surface protein K, a potential pneumococcal vaccine antigen. Virulence 2017:1-16; Advance online publication. PMID:28059611; http://dx.doi.org/10.1080/21505594.2016.1278334
   PubMedGoogle Scholar
• Na IY, Baek JY, Park IH, Kim DH, Song JH, Ko KS. pspK gene prevalence and characterization of non-typable Streptococcus pneumonia isolates from Asian countries. Microbiology 2015; 161:973-9; PMID:25750083; http://dx.doi.org/10.1099/mic.0.000073
   PubMed Web of Science ®Google Scholar
• Kuipers K, Daleke-Schermerhorn MH, Jong WS, ten Hagen-Jongman CM, van Opzeeland F, Simonetti E, Luirink J, de Jonge MI. Salmonella outer membrane vesicles displaying high densities of pneumococcal antigen at the surface offer protection against colonization. Vaccine 2015; 33:2022-9; PMID:25776921; http://dx.doi.org/10.1016/j.vaccine.2015.03.010
   PubMed Web of Science ®Google Scholar
• Keller LE, Luo X, Thornton JA, Seo KS, Moon BY, Robinson DA, McDaniel LS. Immunization with pneumococcal surface protein K of nonencapsulated streptococcus pneumoniae provides protection in a mouse model of colonization. Clin Vaccine Immunol 2015; 22:1146-53; PMID:26311246; http://dx.doi.org/10.1128/CVI.00456-15
   PubMed Web of Science ®Google Scholar