The Streptococcus suis factor H-binding protein: A key to unlocking the blood-brain barrier and access the central nervous system?

References

• Gottschalk M, Segura M, Xu J. Streptococcus suis infections in humans: the Chinese experience and the situation in North America. Anim Health Res Rev 2007; 8:29-45; PMID:17692141; https://doi.org/10.1017/S1466252307001247
   PubMedGoogle Scholar
• Gottschalk M, Xu J, Calzas C, Segura M. Streptococcus suis: a new emerging or an old neglected zoonotic pathogen? Future Microbiol 2010; 5:371-91; PMID:20210549; https://doi.org/10.2217/fmb.10.2
   PubMed Web of Science ®Google Scholar
• Goyette-Desjardins G, Auger JP, Xu J, Segura M, Gottschalk M. Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing. Emerg Microbes Infect 2014; 3:e45; PMID:26038745; https://doi.org/10.1038/emi.2014.45
   PubMed Web of Science ®Google Scholar
• Auger JP, Fittipaldi N, Benoit-Biancamano MO, Segura M, Gottschalk M. Virulence studies of different sequence types and geographical origins of Streptococcus suis serotype 2 in a mouse model of infection. Pathogens 2016; 5:48; https://doi.org/10.3390/pathogens5030048
   Web of Science ®Google Scholar
• Fittipaldi N, Segura M, Grenier D, Gottschalk M. Virulence factors involved in the pathogenesis of the infection caused by the swine pathogen and zoonotic agent Streptococcus suis. Future Microbiol 2012; 7:259-79; PMID:22324994; https://doi.org/10.2217/fmb.11.149
   PubMed Web of Science ®Google Scholar
• Segura M, Calzas C, Grenier D, Gottschalk M. Initial steps of the pathogenesis of the infection caused by Streptococcus suis: fighting against nonspecific defenses. FEBS Lett 2016; 590:3772-99; PMID:27539145; https://doi.org/10.1002/1873-3468.12364
   PubMed Web of Science ®Google Scholar
• Dando SJ, Mackay-Sim A, Norton R, Currie BJ, St John JA, Ekberg JA, Batzloff M, Ulett GC, Beacham IR. Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion. Clin Microbiol Rev 2014; 27:691-726; PMID:25278572; https://doi.org/10.1128/CMR.00118-13
   PubMed Web of Science ®Google Scholar
• Kim KS. Mechanisms of microbial traversal of the blood-brain barrier. Nat Rev Microbiol 2008; 6:625-34; PMID:18604221; https://doi.org/10.1038/nrmicro1952
   PubMed Web of Science ®Google Scholar
• Vanier G, Segura M, Friedl P, Lacouture S, Gottschalk M. Invasion of porcine brain microvascular endothelial cells by Streptococcus suis serotype 2. Infect Immun 2004; 72:1441-49; PMID:14977949; https://doi.org/10.1128/IAI.72.3.1441-1449.2004
   PubMed Web of Science ®Google Scholar
• Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells. Infect Immun 2000; 68:637-43; PMID:10639427; https://doi.org/10.1128/IAI.68.2.637-643.2000
   PubMed Web of Science ®Google Scholar
• Benga L, Friedl P, Valentin-Weigand P. Adherence of Streptococcus suis to porcine endothelial cells. J Vet Med B Infect Dis Vet Public Health 2005; 52:392-5; PMID:16283918; https://doi.org/10.1111/j.1439-0450.2005.00880.x
   PubMedGoogle Scholar
• Vanier G, Segura M, Gottschalk M. Characterization of the invasion of porcine endothelial cells by Streptococcus suis serotype 2. Can J Vet Res 2007; 71:81-9; PMID:17479770
   PubMed Web of Science ®Google Scholar
• Pian Y, Gan S, Wang S, Guo J, Wang P, Zheng Y, Cai X, Jiang Y, Yuan Y. Fhb, a novel factor H-binding surface protein, contributes to the antiphagocytic ability and virulence of Streptococcus suis. Infect Immun 2012; 80:2402-13; PMID:22526676; https://doi.org/10.1128/IAI.06294-11
   PubMed Web of Science ®Google Scholar
• Kouki A, Haataja S, Loimaranta V, Pulliainen AT, Nilsson UJ, Finne J. Identification of a novel streptococcal adhesin P (SadP) protein recognizing galactosyl-alpha1-4 galactose-containing glycoconjugates: convergent evolution of bacterial pathogens to binding of the same host receptor. J Biol Chem 2011; 286:38854-64; PMID:21908601; https://doi.org/10.1074/jbc.M111.260992
   PubMed Web of Science ®Google Scholar
• van de Kar NC, Monnens LA, Karmali MA, van Hinsbergh VW. Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: implications for the pathogenesis of the hemolytic uremic syndrome. Blood 1992; 80:2755-64. PMID:1333300
   PubMed Web of Science ®Google Scholar
• Zhang C, Hao H, Yu Y, Kong D, Chen S, Jiang H, Yuan Y, Zheng Y, Yang M, Jiang Y. Structural basis of the interaction between the meningitis pathogen Streptococcus suis adhesin Fhb and its human receptor. FEBS Lett 2016; 590:1384-92; PMID:27086582; https://doi.org/10.1002/1873-3468.12174
   PubMed Web of Science ®Google Scholar
• Kato K, Ishiwa A. The role of carbohydrates in infection strategies of enteric pathogens. Trop Med Health 2015; 43:41-52; PMID:25859152; https://doi.org/10.2149/tmh.2014-25
   PubMedGoogle Scholar
• Kong D, Chen Z, Wang J, Lv Q, Jiang H, Zheng Y, Xu M, Zhou X, Hao H, Jiang Y. Interaction of factor H-binding protein of Streptococcus suis with globotriaosylceramide promotes the development of meningitis. Virulence 2017; 1-13; Advance online publication. PMID:28402705; https://doi.org/10.1080/21505594.2017.1317426
   PubMed Web of Science ®Google Scholar
• Segura M, Fittipaldi N, Calzas C, Gottschalk M. Critical Streptococcus suis virulence factors: are they all really critical? Trends Microbiol 2017; 25:585-99; PMID:28274524; https://doi.org/10.1016/j.tim.2017.02.005
   PubMed Web of Science ®Google Scholar
• Dominguez-Punaro MC, Segura M, Plante MM, Lacouture S, Rivest S, Gottschalk M. Streptococcus suis serotype 2, an important swine and human pathogen, induces strong systemic and cerebral inflammatory responses in a mouse model of infection. J Immunol 2007; 179:1842-54; PMID:17641051; https://doi.org/10.4049/jimmunol.179.3.1842
   PubMed Web of Science ®Google Scholar
• McKenzie JA, Ridley AJ. Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability. J Cell Physiol 2007; 213:221-8; PMID:17476691; https://doi.org/10.1002/jcp.21114
   PubMed Web of Science ®Google Scholar
• Terry S, Nie M, Matter K, Balda MS. Rho signaling and tight junction functions. Physiology (Bethesda). 2010;25:16-26; PMID:20134025; https://doi.org/10.1152/physiol.00034.2009
   PubMed Web of Science ®Google Scholar
• Gonzalez-Mariscal L, Tapia R, Chamorro D. Crosstalk of tight junction components with signaling pathways. Biochim Biophys Acta 2008; 1778:729-56; PMID:17950242; https://doi.org/10.1016/j.bbamem.2007.08.018
   PubMed Web of Science ®Google Scholar