Dectin-1 plays an important role in host defense against systemic Candida glabrata infection

References

• Bassetti M, Righi E, Costa A, Fasce R, Molinari MP, Rosso R, Pallavicini FB, Viscoli C. Epidemiological trends in nosocomial candidemia in intensive care. BMC Infect Dis 2006; 6:21; PMID:16472387; https://doi.org/https://doi.org/10.1186/1471-2334-6-21
   PubMed Web of Science ®Google Scholar
• Colombo AL, Guimarães T, Silva LR, de Almeida Monfardini LP, Cunha AK, Rady P, Alves T, Rosas RC. Prospective observational study of candidemia in São Paulo, Brazil: incidence rate, epidemiology, and predictors of mortality. Infect Control Hosp Epidemiol 2007; 28:570-76; PMID:17464917; https://doi.org/https://doi.org/10.1086/513615
   PubMed Web of Science ®Google Scholar
• Chakrabarti A, Chatterjee SS, Rao KL, Zameer MM, Shivaprakash MR, Singhi S, Singh R, Varma SC. Recent experience with fungaemia: change in species distribution and azole resistance. Scand. J. Infect. Dis 2009; 41:275-84; PMID:19229762; https://doi.org/https://doi.org/10.1080/00365540902777105
   PubMed Web of Science ®Google Scholar
• Rodrigues CF, Silva S, Henriques M. Candida glabrata: a review of its features and resistance. Eur J Clin Microbiol Infect Dis 2014; 33:673-88; PMID:24249283; https://doi.org/https://doi.org/10.1007/s10096-013-2009-3
   PubMed Web of Science ®Google Scholar
• Pfaller MA, Diekema DJ. Twelve years of fluconazole inclinical practice: global trends in species distribution and fluconazole susceptibility of bloodstream isolates of Candida. Clin Microbiol Infect 2004; 10(Suppl. 1):11-23; PMID:14748799; https://doi.org/https://doi.org/10.1111/j.1470-9465.2004.t01-1-00844.x
   PubMed Web of Science ®Google Scholar
• Kaur R, Domergue R, Zupancic ML, Cormack BP. A yeast by any other name: Candida glabrata and its interaction with the host. Curr opin in microbial 2005; 8:378-84; https://doi.org/https://doi.org/10.1016/j.mib.2005.06.012
   PubMed Web of Science ®Google Scholar
• Almeida AA, Mesquita CS, Svidzinski TI, Oliveira KM. Antifungal susceptibility and distribution of Candida spp. isolates from the University Hospital in the municipality of Dourados, State of Mato Grosso do Sul, Brazil. Rev Soc Bras Med Trop 2013; 46:335-39; PMID:23856873; https://doi.org/https://doi.org/10.1590/0037-8682-0074-2012
   PubMed Web of Science ®Google Scholar
• Lee I, Morales KH, Zaoutis TE, Fishman NO, Nachamkin I, Lautenbach E. Clinical and economic outcomes of decreased fluconazole susceptibility in patients with Candida glabrata bloodstream infections. Am J Infect Control 2010; 38:740-5; PMID:20542354; https://doi.org/https://doi.org/10.1016/j.ajic.2010.02.016
   PubMedGoogle Scholar
• Vermitsky JP1, Edlind TD. Azole Resistance in Candida glabrata: Coordinate Upregulation of Multidrug Transporters and Evidence for a Pdr1-Like Transcription Factor. Antimicrob Agents Chemother 2004; 48:3773-81; PMID:15388433; https://doi.org/https://doi.org/10.1128/AAC.48.10.3773-3781.2004
   PubMed Web of Science ®Google Scholar
• Choo ZW, Chakravarthi S, Wong SF, Nagaraja HS, Thanikachalam PM, Mak JW, Radhakrishnan A, Tay A. A comparative histopathological study of systemic candidiasis in association with experimentally induced breast cancer. Oncol Lett 2010; 1:215-22; PMID:22966285
   PubMed Web of Science ®Google Scholar
• Drummond RA, Lionakis MS. Mechanistic Insights into the Role of C-Type Lectin Receptor/CARD9 Signaling in Human Antifungal Immunity. Front Cell Infect Microbiol 2016; 6:39; PMID:27092298; https://doi.org/https://doi.org/10.3389/fcimb.2016.00039
   PubMedGoogle Scholar
• Ferwerda B, Ferwerda G, Plantinga TS, Willment JA, van Spriel AB, Venselaar H, Elbers CC, Johnson MD, Cambi A, Huysamen C, et al. Human dectin-1 deficiency and mucocutaneous fungal infections. N Engl J Med 2009; 361:1760-7; PMID:19864674; https://doi.org/https://doi.org/10.1056/NEJMoa0901053
   PubMed Web of Science ®Google Scholar
• Hardison SE, Brown GD. C-type lectin receptors orchestrate antifungal immunity. Nat Immunol 2012; 13:817-22; PMID:22910394; https://doi.org/https://doi.org/10.1038/ni.2369
   PubMed Web of Science ®Google Scholar
• Netea MG, Joosten LA, van der Meer JW, Kullberg BJ, van de Veerdonk FL. Immune defence against Candida fungal infections. Nat Rev Immunol 2015; 15:630-42; PMID:26388329; https://doi.org/https://doi.org/10.1038/nri3897
   PubMed Web of Science ®Google Scholar
• Underhill DM, Rossnagle E, Lowell CA, Simmons RM. Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood 2005; 106:2543-50; PMID:15956283; https://doi.org/https://doi.org/10.1182/blood-2005-03-1239
   PubMed Web of Science ®Google Scholar
• Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, et al. Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’. Nature 2011; 472:471-5; PMID:21525931; https://doi.org/https://doi.org/10.1038/nature10071
   PubMed Web of Science ®Google Scholar
• Branzk N, Lubojemska A, Hardison SE, Wang Q, Gutierrez MG, Brown GD, Papayannopoulos V. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat Immunol 2014; 15:1017-25; PMID:25217981; https://doi.org/https://doi.org/10.1038/ni.2987
   PubMed Web of Science ®Google Scholar
• Xu S, Huo J, Lee KG, Kurosaki T, Lam KP. Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells. J Biol Chem 2009; 284:7038-46; PMID:19136564; https://doi.org/https://doi.org/10.1074/jbc.M806650200
   PubMedGoogle Scholar
• Cheng SC, van de Veerdonk FL, Lenardon M, Stoffels M, Plantinga T, Smeekens S, Rizzetto L, Mukaremera L, Preechasuth K, Cavalieri D, et al. The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans. J Leukoc Biol 2011; 90:357-66; PMID:21531876; https://doi.org/https://doi.org/10.1189/jlb.1210702
   PubMed Web of Science ®Google Scholar
• Sato K, Yang XL, Yudate T, Chung JS, Wu J, Luby-Phelps K, Kimberly RP, Underhill D, Cruz PD, Jr, Ariizumi K. Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses. J Biol Chem 2006; 281:38854-66; PMID:17050534; https://doi.org/https://doi.org/10.1074/jbc.M606542200
   PubMed Web of Science ®Google Scholar
• Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, et al. Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J Exp Med 2009; 206:2037-51; PMID:19703985; https://doi.org/https://doi.org/10.1084/jem.20082818
   PubMed Web of Science ®Google Scholar
• Ifrim DC, Bain JM, Reid DM, Oosting M, Verschueren I, Gow NA, van Krieken JH, Brown GD, Kullberg BJ, Joosten LA, et al. Role of Dectin-2 for host defense against systemic infection with Candida glabrata. Infect Immun 2014; 82:1064-73; PMID:24343653; https://doi.org/https://doi.org/10.1128/IAI.01189-13
   PubMed Web of Science ®Google Scholar
• Romani L. Immunity to fungal infections. Nat Rev Immunol 2011; 11:275-88; PMID:21394104; https://doi.org/https://doi.org/10.1038/nri2939
   PubMed Web of Science ®Google Scholar
• Low CY, Rotstein C. Emerging fungal infections in immunocompromised patients. F1000 Med Rep 2011; 3:14; PMID:21876720; https://doi.org/https://doi.org/10.3410/M3-14
   PubMedGoogle Scholar
• Wuthrich M, Deepe GS, Jr., Klein B. Adaptive immunity to fungi. Annu Rev Immunol 2012; 30:115-48; PMID:22224780; https://doi.org/https://doi.org/10.1146/annurev-immunol-020711-074958
   PubMed Web of Science ®Google Scholar
• Gow NA, van de Veerdonk FL, Brown AJ, Netea MG. Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat Rev Microbiol 2012; 10:112-22.
   PubMed Web of Science ®Google Scholar
• Gantner BN, Simmons RM, Underhill DM. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J 2005; 24:1277-1286; PMID:15729357; https://doi.org/https://doi.org/10.1038/sj.emboj.7600594
   PubMed Web of Science ®Google Scholar
• Wheeler RT, Fink GR. A drug-sensitive genetic network masks fungi from the immune system. PLoS Pathog 2006; 2:e35; PMID:16652171; https://doi.org/https://doi.org/10.1371/journal.ppat.0020035
   PubMed Web of Science ®Google Scholar
• Taylor PR, Tsoni SV, Willment JA, Dennehy KM, Rosas M, Findon H, Haynes K, Steele C, Botto M, Gordon S, Brown GD. Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol 2007; 8:31-38; PMID:17159984; https://doi.org/https://doi.org/10.1038/ni1408
   PubMed Web of Science ®Google Scholar
• Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, et al. Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity 2010; 32:681-91; PMID:20493731; https://doi.org/https://doi.org/10.1016/j.immuni.2010.05.001
   PubMed Web of Science ®Google Scholar
• Saijo S, Fujikado N, Furuta T, Chung SH, Kotaki H, Seki K, Sudo K, Akira S, Adachi Y, Ohno N, et al. Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat Immunol 2007; 8:39-46; PMID:17159982; https://doi.org/https://doi.org/10.1038/ni1425
   PubMed Web of Science ®Google Scholar
• Shaoji Cheng, Cornelius J. Clancy, Douglas J. Hartman, Binghua Hao, Nguyen M Hong. Candida glabrata Intra-Abdominal Candidiasis Is Characterized by Persistence within the Peritoneal Cavity and Abscesses. Infect Immun 2014; 82:3015-22; PMID:24799629; https://doi.org/https://doi.org/10.1128/IAI.00062-14
   PubMedGoogle Scholar
• Gazendam RP, van Hamme JL, Tool AT, van Houdt M, Verkuijlen PJ, Herbst M, Liese JG, van de Veerdonk FL, Roos D, van den Berg TK, et al. Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects. Blood 2014; 124:590-7; PMID:24948657; https://doi.org/https://doi.org/10.1182/blood-2014-01-551473
   PubMed Web of Science ®Google Scholar
• Netea MG, Brown GD, Kullberg BJ, Gow NA. An integrated model of the recognition of Candida albicans by the innate immune system. Nat.Rev. Microbiol 2008; 6:67-78; PMID:18079743; https://doi.org/https://doi.org/10.1038/nrmicro1815
   PubMed Web of Science ®Google Scholar
• LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol 2007; 8:630-8; PMID:17450144; https://doi.org/https://doi.org/10.1038/ni1460
   PubMed Web of Science ®Google Scholar
• Netea MG, van Tits LJ, Curfs JH, Amiot F, Meis JF, van der Meer JW, Kullberg BJ. Increased susceptibility of TNF-lymphotoxin-double knockout mice to systemic candidiasis through impaired recruitment of neutrophils and phagocytosis of Candida albicans. J Immunol 1999; 163:1498-505; PMID:10415052
   PubMed Web of Science ®Google Scholar
• Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F. Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 2012; 484:514-8; PMID:22466287; https://doi.org/https://doi.org/10.1038/nature10957
   PubMed Web of Science ®Google Scholar
• Hernandez-Santos N, Gaffen SL. Th17 cells in immunity to Candida albicans. Cell Host Microbe 2012; 11:425-35; PMID:22607796; https://doi.org/https://doi.org/10.1016/j.chom.2012.04.008
   PubMed Web of Science ®Google Scholar
• Wenzel U, Schneider A, Valente AJ, Abboud HE, Thaiss F, Helmchen UM, Stahl RA. Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis. Kidney Int 1997; 51:770-6; PMID:9067909; https://doi.org/https://doi.org/10.1038/ki.1997.108
   PubMedGoogle Scholar
• de Groot PW, Kraneveld EA, Yin QY, Dekker HL, Gross U, Crielaard W, de Koster CG, Bader O, Klis FM, Weig M. The cell wall of the human pathogen Candida glabrata: differential incorporation of novel adhesin-like wall proteins. Eukaryot Cell 2008; 7:1951-64; PMID:18806209; https://doi.org/https://doi.org/10.1128/EC.00284-08
   PubMed Web of Science ®Google Scholar
• Csank C, Haynes K. Candida glabrata displays pseudohyphal growth. FEMS Microbiol. Lett 2000; 189:115-20; PMID:10913876; https://doi.org/https://doi.org/10.1111/j.1574-6968.2000.tb09216.x
   PubMed Web of Science ®Google Scholar
• Vautier S, Drummond RA, Redelinghuys P, Murray GI, MacCallum DM, Brown GD. Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract. Infect Immun 2012; 80:4216-22; PMID:22988015; https://doi.org/https://doi.org/10.1128/IAI.00559-12
   PubMed Web of Science ®Google Scholar
• Yamane H, Sugimoto Y, Tanaka S, Ichikawa A. Prostaglandin E2 Receptors, EP2 and EP4, differentially modulate TNF-a and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. Biochem Biophys Res Commun 2000; 278:224-8; PMID:11071876; https://doi.org/https://doi.org/10.1006/bbrc.2000.3779
   PubMed Web of Science ®Google Scholar
• Zhang SQ, Zou Z, Shen H, Shen SS, Miao Q, Huang X, Liu W, Li LP, Chen SM, Yan L, et al. Mnn10 Maintains Pathogenicity in Candida albicans by Extending alpha-1,6-Mannose Backbone to Evade Host Dectin-1 Mediated Antifungal Immunity. PLoS pathog 2016; 12:e1005617; PMID:27144456; https://doi.org/https://doi.org/10.1371/journal.ppat.1005617
   PubMed Web of Science ®Google Scholar
• Shen H, Chen SM, Liu W, Zhu F, He LJ, Zhang JD, Zhang SQ, Yan L, Xu Z, Xu GT, et al. Abolishing Cell Wall Glycosylphosphatidylinositol-Anchored Proteins in Candida albicans Enhances Recognition by Host Dectin-1. Infect immun 2015; 83:2694-704; PMID:25895969; https://doi.org/https://doi.org/10.1128/IAI.00097-15
   PubMedGoogle Scholar