Antigenicity analysis of human parvovirus B19-VP1u protein in the induction of anti-phospholipid syndrome

References

• Lunardi C, Tiso M, Borgato L, Nanni L, Millo R, De Sandre G, Severi AB, Puccetti A. Chronic parvovirus B19 infection induces the production of anti-virus antibodies with autoantigen binding properties. Eur J Immunol. 1998;28:936–948. doi:10.1002/(SICI)1521-4141(199803)28:03<936::AID-IMMU936>3.3.CO;2-O 10.1002/(SICI)1521-4141(199803)28:03<936::AID-IMMU936>3.0.CO;2-X. PMID:9541589
   PubMed Web of Science ®Google Scholar
• Bertolaccini M, Khamashta MA. Laboratory diagnosis and management challenges in the antiphospholipid syndrome. Lupus. 2006;15:172–178. doi:10.1191/0961203306lu2293rr. PMID:16634372
   PubMed Web of Science ®Google Scholar
• Von Landenberg P, Lehmann HW, Modrow S. Human parvovirus B19 infection and antiphospholipid antibodies. Autoimmun Rev. 2007;6:278–285. doi:10.1016/j.autrev.2006.09.006. PMID:17412298
   PubMed Web of Science ®Google Scholar
• Pavlovic M, Kats A, Cavallo M, Shoenfeld Y. Clinical and molecular evidence for association of SLE with parvovirus B19. Lupus. 2010;19:783–792. doi:10.1177/0961203310365715. PMID:20511275
   PubMedGoogle Scholar
• Young NS, Brown KE. Parvovirus B19. N Engl J Med. 2004;350:586–97. doi:10.1056/NEJMra030840. PMID:14762186
   PubMed Web of Science ®Google Scholar
• Qiu J, Söderlund-Venermo M, Young NS. Human Parvoviruses. Clin Microbiol Rev. 2017;30:43–113. doi:10.1128/CMR.00040-16. PMID:27806994
   PubMed Web of Science ®Google Scholar
• Lehmann HW, von Landenberg P, Modrow S. Parvovirus B19 infection and autoimmune disease. Autoimmun Rev. 2003;2:218–223. doi:10.1016/S1568-9972(03)00014-4. PMID:12848949
   PubMed Web of Science ®Google Scholar
• Meyer O. Parvovirus B19 and autoimmune diseases. Joint Bone Spine. 2003;70:6–11. doi:10.1016/S1297-319X(02)00004-0. PMID:12639611
   PubMed Web of Science ®Google Scholar
• Loizou S, Cazabon JK, Walport MJ, Tait D, So AK. Similarities of specificity and cofactor dependence in serum antiphospholipid antibodies from patients with human parvovirus B19 infection and from those with systemic lupus erythematosus. Arthritis Rheum. 1997;40:103–108. doi:10.1002/art.1780400115. PMID:9008606
   PubMed Web of Science ®Google Scholar
• von Landenberg P, Lehmann HW, Knoll A, Dorsch S, Modrow S. Antiphospholipid antibodies in pediatric and adult patients with rheumatic disease are associated with parvovirus B19 infection. Arthritis Rheum. 2003;48:1939–1947. doi:10.1002/art.11038. PMID:12847688
   PubMed Web of Science ®Google Scholar
• Sène D, Piette JC, Cacoub P. Antiphospholipid antibodies, antiphospholipid syndrome and infections. Autoimmun Rev. 2008;7:272–277. doi:10.1016/j.autrev.2007.10.001. PMID:18295729
   PubMed Web of Science ®Google Scholar
• Hsu TC, Tsay GJ. Human parvovirus B19 infection in patients with systemic lupus erythematosus. Rheumatology (Oxford). 2001;40:152–157. doi:10.1093/rheumatology/40.2.152. PMID:11257151
   PubMed Web of Science ®Google Scholar
• Kalt M, Gertner E. Antibodies to beta 2-glycoprotein I and cardiolipin with symptoms suggestive of systemic lupus erythematosus in parvovirus B19 infection. J Rheumatol. 2001;28:2335–2336. PMID:11669178
   PubMed Web of Science ®Google Scholar
• Von Landenberg P, Modrow S. Human parvovirus B19 infection and antiphospholipid- syndrome: the two sides of one medal? J Vet Med B Infect Dis Vet Public Health. 2005;52:353–355. doi:10.1111/j.1439-0450.2005.00876.x. PMID:16316400
   PubMedGoogle Scholar
• von Landenberg P, Döring Y, Modrow S, Lackner KJ. Are antiphospholipid antibodies an essential requirement for an effective immune response to infections? Ann N Y Acad Sci. 2007;1108:578–583. doi:10.1196/annals.1422.060. PMID:17894022
   PubMed Web of Science ®Google Scholar
• Tzang BS, Tsay GJ, Lee YJ, Li C, Sun YS, Hsu TC. The association of VP1 unique region protein in acute parvovirus B19 infection and antiphospholipid antibody production. Clin Chim Acta. 2007;378:59–65. doi:10.1016/j.cca.2006.10.016. PMID:17169353
   PubMed Web of Science ®Google Scholar
• Tzang BS, Lee YJ, Yang TP, Tsay GJ, Shi JY, Tsai CC, Hsu TC. Induction of antiphospholipid antibodies and antiphospholipid syndrome-like autoimmunity in naive mice with antibody against human parvovirus B19 VP1 unique region protein. Clin Chim Acta. 2007;382:31–36. doi:10.1016/j.cca.2007.03.014. PMID:17451664
   PubMed Web of Science ®Google Scholar
• Tzang BS, Chiu CC, Tsai CC, Lee YJ, Lu IJ, Shi JU, Hsu TC. Effects of human parvovirus B19 VP1 unique region protein on macrophage responses. J Biomed Sci. 2009;16:13. doi:10.1186/1423-0127-16-13. PMID:19272185
   PubMed Web of Science ®Google Scholar
• Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680–684. doi:10.1038/227680a0. PMID:5432063
   PubMed Web of Science ®Google Scholar
• Towbin H, Stachelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamid gels to nitrocellulose sheet: procedure and some applications. Proc Natl Acad Sci USA. 1979;76:4350–4354. doi:10.1073/pnas.76.9.4350. PMID:388439
   PubMed Web of Science ®Google Scholar
• Olszewska W, Obeid OE, Steward MW. Protection against measles virus-induced encephalitis by anti-mimotope antibodies: the role of antibody affinity. Virology. 2000;272:98–105. doi:10.1006/viro.2000.0285. PMID:10873752
   PubMed Web of Science ®Google Scholar
• Li J, Zhang WB, Wilson M, Ito A, McManus DP. A novel recombinant antigen for immunodiagnosis of human cystic echinococcosis. J Infect Dis. 2003;188:1951–1960. doi:10.1086/379976. PMID:14673776
   PubMed Web of Science ®Google Scholar
• Vignier N, Amor F, Fogel P, Duvallet A, Poupiot J, Charrier S, Arock M, Montus M, Nelson I, Richard I, et al. Distinctive serum miRNA profile in mouse models of striated muscular pathologies. PLoS One. 2013;8:e55281. doi:10.1371/journal.pone.0055281. PMID:23418438
   PubMed Web of Science ®Google Scholar
• Blank M, Cohen J, Toder V, Shoenfeld Y. Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies. Proc Natl Acad Sci U S A. 1991;88:3069–3073. doi:10.1073/pnas.88.8.3069. PMID:2014226
   PubMed Web of Science ®Google Scholar
• Anderson S, Momoeda M, Kawase M, Kajigaya S, Young NS. Peptides derived from the unique region of B19 parvovirus minor capsid protein elicit neutralizing antibodies in rabbits. Virology. 1995;206:626–632. doi:10.1016/S0042-6822(95)80079-4. PMID:7530397
   PubMed Web of Science ®Google Scholar
• Zadori Z, Szelei J, Lacoste MC, Li Y, Gariépy S, Raymond P, Allaire M, Nabi IR, Tijssen P. A viral phospholipase A2 is required for parvovirus infectivity. Dev Cell. 2001;1:291–302. doi:10.1016/S1534-5807(01)00031-4. PMID:11702787
   PubMed Web of Science ®Google Scholar
• Dorsch S, Liebisch G, Kaufmann B, von Landenberg P, Hoffmann JH, Drobnik W, Modrow S. The VP1 unique region of parvovirus B19 and its constituent phospholipase A2-like activity. J Virol. 2002;76:2014–2018. doi:10.1128/JVI.76.4.2014-2018.2002. PMID:11799199
   PubMed Web of Science ®Google Scholar
• Lu J, Zhi N, Wong S, Brown KE. Activation of synoviocytes by the secreted phospholipase A2 motif in the VP1-unique region of parvovirus B19 minor capsid protein. J Infect Dis. 2006;193:582–590. doi:10.1086/499599. PMID:16425138
   PubMed Web of Science ®Google Scholar
• Filippone C, Zhi N, Wong S, Lu J, Kajigaya S, Gallinella G, Kakkola L, Söderlund-Venermo M, Young NS, Brown KE. VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones. Virology. 2008;374:444–452. doi:10.1016/j.virol.2008.01.002. PMID:18252260
   PubMed Web of Science ®Google Scholar
• Saikawa T, Anderson S, Momoeda M, Kajigaya S, Young NS. Neutralizing linear epitopes of B19 parvovirus cluster in the VP1 unique and VP1-VP2 junction regions. J Virol. 1993;67:3004–3009. PMID:7684458
   PubMed Web of Science ®Google Scholar
• Zuffi E, Manaresi E, Gallinella G, Gentilomi GA, Venturoli S, Zerbini M, Musiani M. Identification of an immunodominant peptide in the parvovirus B19 VP1 unique region able to elicit a long-lasting immune response in humans. Viral Immunology. 2001;14:151–158. doi:10.1089/088282401750234529. PMID:11398810
   PubMed Web of Science ®Google Scholar
• Leisi R, Ruprecht N, Kempf C, Ros C. Parvovirus B19 uptake is a highly selective process controlled by VP1u: A novel determinant of viral tropism. J Virol. 2013;87:13161–13167. doi:10.1128/JVI.02548-13. PMID:24067971
   PubMed Web of Science ®Google Scholar
• Leisi R, Di Tommaso C, Kempf C, Ros C. The Receptor-Binding Domain in the VP1u Region of Parvovirus B19. Viruses. 2016;8:61. doi:10.3390/v8030061. PMID:26927158
   PubMed Web of Science ®Google Scholar
• Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RHWM, deGroot PG, Koike T, Meroni PL, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4:295–306. doi:10.1111/j.1538-7836.2006.01753.x. PMID:16420554
   PubMed Web of Science ®Google Scholar
• Pengo V, Banzato A, Bison E, Denas G, Zoppellaro G, Bracco A, Padayattil Jose S, Hoxha A, Ruffatti A. Laboratory testing for antiphospholipid syndrome. Int J Lab Hematol 2016;38(Suppl 1):27–31. doi:10.1111/ijlh.12507. PMID:27161602
   PubMed Web of Science ®Google Scholar
• Tzang BS, Tsai CC, Chiu CC, Shi JY, Hsu TC. Up-regulation of adhesion molecule expression and induction of TNF-alpha on vascular endothelial cells by antibody against human parvovirus B19 VP1 unique region protein. Clin Chim Acta. 2008;395:77–83 doi:10.1016/j.cca.2008.05.012. PMID:18538665
   PubMed Web of Science ®Google Scholar
• Hsu TC, Chiu CC, Chang SC, Chan HC, Shi YF, Chen TY, Tzang BS. Human parvovirus B19 VP1u Protein as inflammatory mediators induces liver injury in naïve mice. Virulence. 2016;7:110–118. doi:10.1080/21505594.2015.1122165. PMID:26632342
   PubMed Web of Science ®Google Scholar
• Adamson-Small LA, Ruiz-Ordaz BH. Hepatic inflammation resulting from localized, subcutaneous expression of Parvovirus VP1u capsid protein: Importance and implication. Virulence. 2016;7:70–71. doi:10.1080/21505594.2016.1141163. PMID:26786960
   PubMed Web of Science ®Google Scholar