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Editorial - Commissioned

Highly pathogenic avian H5N8 influenza viruses: should we be concerned?

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Pages 20-21 | Received 27 Sep 2017, Accepted 27 Sep 2017, Published online: 27 Nov 2017

References

  • Lee DH, Bertran K, Kwon JH, Swayne DE. Evolution, global spread, and pathogenicity of highly pathogenic avian influenza H5Nx clade 2.3.4.4. J Vet Sci. 2017;18:269–80. doi:10.4142/jvs.2017.18.S1.269. PMID:28859267
  • El-Shesheny R, Barman S, Feeroz MM, Hasan MK, Jones-Engel L, Franks J, Turner J, Seiler P, Walker D, Friedman K, et al. Genesis of influenza A(H5N8) viruses. Emerg Infect Dis. 2017;23:1368–71. doi:10.3201/eid2308.170143. PMID:28609260
  • Jeong J, Kang HM, Lee EK, Song BM, Kwon YK, Kim HR, Choi KS, Kim JY, Lee HJ, Moon OK, et al. Highly pathogenic avian influenza virus (H5N8) in domestic poultry and its relationship with migratory birds in South Korea during 2014. Vet Microbiol. 2014;173:249–57. doi:10.1016/j.vetmic.2014.08.002. PMID:25192767
  • Park SJ, Kim EH, Kwon HI, Song MS, Kim SM, Kim YI, Si YJ, Lee IW, Nguyen HD, Shin OS, et al. Altered virulence of highly pathogenic avian influenza (HPAI) H5N8 reassortant viruses in mammalian models. Virulence. 2017:1–17. doi:10.1080/21505594.2017.1366408. PMID:28873012
  • Wu H, Peng X, Lu R, Xu L, Liu F, Cheng L, Lu X, Yao H, Wu N. Virulence of an H5N8 highly pathogenic avian influenza is enhanced by the amino acid substitutions PB2 E627K and HA A149V. Infect Genet Evol. 2017;54:347–54. doi:10.1016/j.meegid.2017.07.026. PMID:28750900
  • Choi WS, Baek YH, Kwon JJ, Jeong JH, Park SJ, Kim YI, Yoon SW, Hwang J, Kim MH, Kim CJ, et al. Rapid acquisition of polymorphic virulence markers during adaptation of highly pathogenic avian influenza H5N8 virus in the mouse. Sci Rep. 2017;7:40667. doi:10.1038/srep40667. PMID:28094780
  • Mehle A, Doudna JA. Adaptive strategies of the influenza virus polymerase for replication in humans. Proc Natl Acad Sci U S A. 2009;106:21312–6. doi:10.1073/pnas.0911915106. PMID:19995968
  • Steel J, Lowen AC, Mubareka S, Palese P. Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N. PLoS Pathog. 2009;5:e1000252. doi:10.1371/journal.ppat.1000252. PMID:19119420
  • Gao Y, Zhang Y, Shinya K, Deng G, Jiang Y, Li Z, Guan Y, Tian G, Li Y, Shi J, et al. Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host. PLoS Pathog. 2009;5:e1000709. doi:10.1371/journal.ppat.1000709. PMID:20041223
  • Xu W, Dai Y, Hua C, Wang Q, Zou P, Deng Q, Jiang S, Lu L. Genomic signature analysis of the recently emerged highly pathogenic A(H5N8) avian influenza virus: Implying an evolutionary trend for bird-to-human transmission. Microbes Infect. 2017;S1286–4579(17):30121–1. doi:10.1016/j.micinf.2017.08.006. PMID:28889970