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Research Paper

Spontaneous point mutations in the capsule synthesis locus leading to structural and functional changes of the capsule in serogroup A meningococcal populations

, , ORCID Icon, , , ORCID Icon, , & ORCID Icon show all
Pages 1138-1149 | Received 12 Jan 2018, Accepted 13 Apr 2018, Published online: 01 Aug 2018

References

  • Caugant DA, Maiden MCJ. Meningococcal carriage and disease–population biology and evolution. Vaccine. 2009;27(Suppl 2):B64–70.
  • Brouwer MC, Tunkel AR, Beek DVD. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev. 2010;23(3):467–492.
  • Pizza M, Rappuoli R. Neisseria meningitidis: pathogenesis and immunity. Curr Opin Microbiol. 2014;23C:68–72.
  • Harrison LH, Trotter CL, Ramsay ME. Global epidemiology of meningococcal disease. Vaccine. 2009;27(Suppl 2):B51–63.
  • Vogel U. Molecular epidemiology of meningococci: application of DNA sequence typing. Int J Med Microbiol IJMM. 2010;300(7):415–420.
  • Trotter CL, Greenwood BM. Meningococcal carriage in the African meningitis belt. Lancet Infect Dis. 2007;7(12):797–803.
  • MenAfriCar Consortium. Meningococcal carriage in the African meningitis belt. Trop Med Int Health TM IH. 2013;18(8):968–978.
  • Marc LaForce F, Ravenscroft N, Djingarey M, et al. Epidemic meningitis due to Group A Neisseria meningitidis in the African meningitis belt: a persistent problem with an imminent solution. Vaccine. 2009;27(Suppl 2):B13–19.
  • Teyssou R, Muros-Le Rouzic E. Meningitis epidemics in Africa: a brief overview. Vaccine. 2007;25(Suppl 1):A3–7.
  • Nicolas P, Décousset L, Riglet V, et al. Clonal expansion of sequence type (ST-)5 and emergence of ST-7 in serogroup A meningococci, Africa. Emerg Infect Dis. 2001;7(5):849–854.
  • Caugant DA, Nicolas P. Molecular surveillance of meningococcal meningitis in Africa. Vaccine. 2007;25(Suppl 1):A8–11.
  • Lamelas A, Harris SR, Röltgen K, et al. Emergence of a new epidemic Neisseria meningitidis serogroup a clone in the African meningitis belt: high-resolution picture of genomic changes that mediate immune evasion. mBio. 2014;5(5):e01974–14.
  • Huber CA, Pflüger V, Hamid A-WM, et al. Lack of antigenic diversification of major outer membrane proteins during clonal waves of Neisseria meningitidis serogroup A colonization and disease. Pathog Dis. 2013;67(1):4–10.
  • Leimkugel J, Hodgson A, Forgor AA, et al. Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight- year longitudinal study in northern Ghana. PLoS Med. 2007;4(3):e101.
  • Leimkugel J, Forgor AA, Dangy J-P, et al. Genetic diversification of Neisseria meningitidis during waves of colonization and disease in the meningitis belt of sub-Saharan Africa. Vaccine. 2007;25(Suppl 1):A18–23.
  • Harrison OB, Claus H, Jiang Y, et al. Description and nomenclature of Neisseria meningitidis capsule locus. Emerg Infect Dis. 2013;19(4):566–573.
  • Gudlavalleti SK, Datta AK, Tzeng Y-L, et al. The Neisseria meningitidis serogroup A capsular polysaccharide O-3 and O-4 acetyltransferase. J Biol Chem. 2004;279(41):42765–42773.
  • Jolley KA, Brehony C, Maiden MCJ. Molecular typing of meningococci: recommendations for target choice and nomenclature. FEMS Microbiol Rev. 2007;31(1):89–96.
  • Tzeng Y-L, Thomas J, Stephens DS. Regulation of capsule in Neisseria meningitidis. Crit Rev Microbiol. 2015;1–14.
  • Gagneux S, Hodgson A, Ehrhard I, et al. Microheterogeneity of serogroup A (subgroup III) Neisseria meningitidis during an outbreak in northern Ghana. Trop Med Int Health TM IH. 2000;5(4):280–287.
  • Sié A, Pflüger V, Coulibaly B, et al. ST2859 serogroup A meningococcal meningitis outbreak in Nouna Health District, Burkina Faso: a prospective study. Trop Med Int Health TM IH. 2008;13(6):861–868.
  • Anti-Meningococcal Serogroup A mAb [Internet]. [cited 2015 Nov 19]. Available from: http://www.nibsc.org/products/brm_product_catalogue/detail_page.aspx?catid=95/674
  • Koeberling O, Ispasanie E, Hauser J, et al. A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalized modules for membrane antigens (GMMA). Vaccine. 2014;32(23):2688–2695.
  • Koeberling O, Seubert A, Santos G, et al. Immunogenicity of a meningococcal native outer membrane vesicle vaccine with attenuated endotoxin and over-expressed factor H binding protein in infant rhesus monkeys. Vaccine. 2011;29(29–30):4728–4734.
  • Giuntini S, Reason DC, Granoff DM. Complement-mediated bactericidal activity of anti-factor H binding protein monoclonal antibodies against the meningococcus relies upon blocking factor H binding. Infect Immun. 2011;79(9):3751–3759.
  • Tzeng Y-L, Datta AK, Strole CA, et al. Translocation and surface expression of lipidated serogroup B capsular Polysaccharide in Neisseria meningitidis. Infect Immun. 2005;73(3):1491–1505.
  • Swartley JS, Liu LJ, Miller YK, et al. Characterization of the gene cassette required for biosynthesis of the (alpha1–>6)-linked N-acetyl-D-mannosamine-1-phosphate capsule of serogroup A Neisseria meningitidis. J Bacteriol. 1998;180(6):1533–1539.
  • Berti F, Romano MR, Micoli F, et al. Relative stability of meningococcal serogroup A and X polysaccharides. Vaccine. 2012;30(45):6409–6415.
  • Lo H, Tang CM, Exley RM. Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development. Lancet Infect Dis. 2009;9(7):418–427.
  • Hill DJ, Griffiths NJ, Borodina E, et al. Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease. Clin Sci Lond Engl 1979. 2010;118(9):547–564.
  • Altmann D, Aseffa A, Bash M, et al. Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt. Vaccine. 2013;31(11):1453–1457.
  • LaForce FM, Konde K, Viviani S, et al. The meningitis vaccine project. Vaccine. 2007;25(Suppl 1):A97–100.
  • McIntyre PB, O’Brien KL, Greenwood B, et al. Effect of vaccines on bacterial meningitis worldwide. Lancet. 2012;380(9854):1703–1711.
  • Stephens DS, Greenwood B, Brandtzaeg P. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet. 2007;369(9580):2196–2210.
  • Yazdankhah SP, Caugant DA. Neisseria meningitidis: an overview of the carriage state. J Med Microbiol. 2004;53(Pt9):821–832.
  • Claus H, Maiden MCJ, Maag R, et al. Many carried meningococci lack the genes required for capsule synthesis and transport. Microbiology. 2002;148(6):1813–1819.
  • Findlow H, Vogel U, Mueller JE, et al. Three cases of invasive meningococcal disease caused by a capsule null locus strain circulating among healthy carriers in Burkina Faso. J Infect Dis. 2007;195(7):1071–1077.
  • Dolan-Livengood JM, Miller YK, Martin LE, et al. Genetic basis for nongroupable Neisseria meningitidis. J Infect Dis. 2003;187(10):1616–1628.
  • Stephens DS. Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis. Vaccine. 2009;27(Suppl 2):B71–77.
  • Trivedi K, Tang CM, Exley RM. Mechanisms of meningococcal colonisation. Trends Microbiol. 2011;19(9):456–463.
  • Coureuil M, Join-Lambert O, Lécuyer H, et al. Pathogenesis of meningococcemia. Cold Spring Harb Perspect Med. 2013;3(6):a012393.
  • Agarwal S, Vasudhev S, DeOliveira RB, et al. Inhibition of the classical pathway of complement by meningococcal capsular polysaccharides. J Immunol Baltim Md 1950. 2014;193(4):1855–1863.
  • Uria MJ, Zhang Q, Li Y, et al. A generic mechanism in Neisseria meningitidis for enhanced resistance against bactericidal antibodies. J Exp Med. 2008;205(6):1423–1434.
  • Berry DS, Lynn F, Lee C-H, et al. Effect of O acetylation of Neisseria meningitidis serogroup A capsular polysaccharide on development of functional immune responses. Infect Immun. 2002;70(7):3707–3713.
  • Richmond P, Borrow R, Findlow J, et al. Evaluation of De-O-acetylated meningococcal C polysaccharide-tetanus toxoid conjugate vaccine in infancy: reactogenicity, immunogenicity, immunologic priming, and bactericidal activity against O-acetylated and De-O-acetylated serogroup C strains. Infect Immun. 2001;69(4):2378–2382.