Galleria mellonella experimental model for bat fungal pathogen Pseudogymnoascus destructans and human fungal pathogen Pseudogymnoascus pannorum

References

• Ingersoll TE, Sewall BJ, Amelon SK. Effects of white‐nose syndrome on regional population patterns of 3 hibernating bat species. Conservation Biol. 2016;30(5):1048–1059.
   PubMed Web of Science ®Google Scholar
• Pettit JL, O’Keefe JM. Impacts of white-nose syndrome observed during long-term monitoring of a midwestern bat community. J Wildl Manag. 2017;8(1):69–78.
   Web of Science ®Google Scholar
• Hayman DT, Pulliam JR, Marshall JC, et al. Environment, host, and fungal traits predict continental-scale white-nose syndrome in bats. Sci Advances. 2016;2(1):e1500831.
   PubMed Web of Science ®Google Scholar
• Zukal J, Bandouchova H, Brichta J, et al. White-nose syndrome without borders: Pseudogymnoascus destructans infection tolerated in Europe and Palearctic Asia but not in North America. Sci Rep. 2016;6:19829.
   PubMed Web of Science ®Google Scholar
• Minnis AM, Lindner DL. Phylogenetic evaluation of Geomyces and allies reveals no close relatives of Pseudogymnoascus destructans, comb. nov., in bat hibernacula of eastern North America. Fungal Biology. 2013 Sep;117(9):638–649. PubMed PMID: WOS:000324899800006; English.
   PubMed Web of Science ®Google Scholar
• Reynolds HT, Ingersoll T, Barton HA. Modeling the environmental growth of Pseudogymnoascus destructans and its impact on the white-nose syndrome epidemic. J Wildl Dis. 2015 Apr;51(2):318–331. PubMed PMID: 25588008; eng.
   PubMed Web of Science ®Google Scholar
• Blehert DS, Hicks AC, Behr M, et al. Bat white-nose syndrome: an emerging fungal pathogen? Science. 2009 Jan 9;323(5911):227. PubMed PMID: 18974316; eng.
   PubMed Web of Science ®Google Scholar
• Chaturvedi V, Springer DJ, Behr MJ, et al. Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with White Nose Syndrome (WNS). PLoS One. 2010 May 24;5(5):e10783. PubMed PMID: 20520731; PubMed Central PMCID: PMCPMC2875398.
   PubMed Web of Science ®Google Scholar
• Cryan PM, Meteyer CU, Boyles JG, et al. Wing pathology of white-nose syndrome in bats suggests life-threatening disruption of physiology. BMC Biol. 2010 Nov 11;8(1):135. PubMed PMID: 21070683; PubMed Central PMCID: PMCPMC2984388. eng.
   PubMed Web of Science ®Google Scholar
• Reeder DM, Frank CL, Turner GG, et al. Frequent arousal from hibernation linked to severity of infection and mortality in bats with white-nose syndrome. PLoS One. 2012;7(6):e38920. PubMed PMID: 22745688; PubMed Central PMCID: PMCPMC3380050. eng.
   PubMed Web of Science ®Google Scholar
• Turner JM, Warnecke L, Wilcox A, et al. Conspecific disturbance contributes to altered hibernation patterns in bats with white-nose syndrome. Physiol Behav. 2015 Mar 1;140:71–78. PubMed PMID: 25484358; eng.
   PubMed Web of Science ®Google Scholar
• Puechmaille SJ, Wibbelt G, Korn V, et al. Pan-European distribution of white-nose syndrome fungus (Geomyces destructans) not associated with mass mortality. PLoS One. 2011 Apr 27;6(4):e19167. PubMed PMID: 21556356; PubMed Central PMCID: PMCPMC3083413. eng.
   PubMed Web of Science ®Google Scholar
• Frank CL, Michalski A, McDonough AA, et al. The resistance of a North American bat species (Eptesicus fuscus) to white-nose syndrome (WNS). PLoS One. 2014;9(12):e113958.
   PubMed Web of Science ®Google Scholar
• Pikula J, Amelon SK, Bandouchova H, et al. White-nose syndrome pathology grading in Nearctic and Palearctic bats. PloS One. 2017;12(8):e0180435.
   PubMed Web of Science ®Google Scholar
• Köhler JR, Casadevall A, Perfect J. The spectrum of fungi that infects humans. Cold Spring Harb Perspect Med. 2015;5(1). DOI:10.1101/cshperspect.a019273.
   Web of Science ®Google Scholar
• Zelenkova H. Geomyces pannorum as a possible causative agent of dermatomycosis and onychomycosis in two patients. Acta Dermatovenerol Croat. 2006;14(1): 21–25. PubMed PMID: 16603097; eng.
   PubMedGoogle Scholar
• Gianni C, Caretta G, Romano C. Skin infection due to Geomyces pannorum var. pannorum. Mycoses. 2003;46(9–10): 430–432. PubMed PMID: 14622395; eng.
   PubMed Web of Science ®Google Scholar
• Christen-Zaech S, Patel S, Mancini AJ. Recurrent cutaneous Geomyces pannorum infection in three brothers with ichthyosis. J Am Acad Dermatol. 2008 May;58(5 Suppl 1):S112–3. PubMed PMID: 18489040; eng.
   PubMed Web of Science ®Google Scholar
• Chibucos MC, Crabtree J, Nagaraj S, et al. draft genome sequences of human pathogenic fungus Geomyces pannorum sensu lato and bat white nose syndrome Pathogen Geomyces (Pseudogymnoascus) destructans. Genome Announc. 2013 Dec 19;1(6). PubMed PMID: 24356829; PubMed Central PMCID: PMCPMC3868853.
   PubMedGoogle Scholar
• Zhang T, Ren P, Chaturvedi V, et al. Development of an Agrobacterium-mediated transformation system for the cold-adapted fungi Pseudogymnoascus destructans and P. pannorum. Fungal Genet Biology. 2015;81:73–81.
   PubMed Web of Science ®Google Scholar
• Zhang T, Ren P, de Jesus M, et al. Green fluorescent protein expression in Pseudogymnoascus destructans to study its abiotic and biotic lifestyles [journal article]. Mycopathologia. 2018 July 09. DOI:10.1007/s11046-018-0285-2.
   Web of Science ®Google Scholar
• Fuchs BB, O’Brien E, El Khoury JB, et al. Methods for using Galleria mellonella as a model host to study fungal pathogenesis. Virulence. 2010;1(6):475–482.
   PubMed Web of Science ®Google Scholar
• Wuensch A, Trusch F, Iberahim NA, et al. Galleria melonella as an experimental in vivo host model for the fish-pathogenic oomycete Saprolegnia parasitica. Fungal Biology. 2018;122(2–3):182–189.
   PubMed Web of Science ®Google Scholar
• Khan S, Nadir S, Lihua G, et al. Identification and characterization of an insect toxin protein, Bb70p, from the entomopathogenic fungus, Beauveria bassiana, using Galleria mellonella as a model system. J Invertebr Pathol. 2016 Jan;133:87–94. PubMed PMID: 26592942.
   PubMed Web of Science ®Google Scholar
• Borman AM. Of mice and men and larvae: galleria mellonella to model the early host-pathogen interactions after fungal infection. Virulence. 2018 Jan 1;9(1):9–12. PubMed PMID: 28933671.
   PubMed Web of Science ®Google Scholar
• de Lacorte Singulani J, Scorzoni L, Esac DP, et al. Evaluation of the efficacy of antifungal drugs against Paracoccidioides brasiliensis and Paracoccidioides lutzii in a Galleria mellonella model. Int J Antimicrob Agents. 2016 Sep;48(3):292–297. PubMed PMID: 27444116.
   PubMed Web of Science ®Google Scholar
• Mylonakis E. Galleria mellonella and the study of fungal pathogenesis: making the case for another genetically tractable model host. Mycopathologia. 2008 Jan;165(1):1–3. PubMed PMID: 18060516; eng.
   PubMed Web of Science ®Google Scholar
• Browne N, Surlis C, Kavanagh K. Thermal and physical stresses induce a short-term immune priming effect in Galleria mellonella larvae. J Insect Physiol. 2014;63:21–26.
   PubMed Web of Science ®Google Scholar
• Mowlds P, Kavanagh K. Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans [journal article]. Mycopathologia. 2008 January 1;165(1):5–12.
   PubMed Web of Science ®Google Scholar
• Bergin D, Brennan M, Kavanagh K. Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella. Microbes Infect. 2003;5(15):1389–1395.
   PubMed Web of Science ®Google Scholar
• Torres MP, Entwistle F, Coote PJ. Effective immunosuppression with dexamethasone phosphate in the Galleria mellonella larva infection model resulting in enhanced virulence of Escherichia coli and Klebsiella pneumoniae. Med Microbiol Immunol. 2016 Aug;205(4):333–343. PubMed PMID: 26920133; PubMed Central PMCID: PMCPMC4939170.
   PubMed Web of Science ®Google Scholar
• Heitmueller M, Billion A, Dobrindt U, et al. Epigenetic mechanisms regulate innate immunity against uropathogenic and commensal-like Escherichia coli in the surrogate insect model Galleria mellonella. Infect Immun. 2017 Oct;85(10):e00336-17. PubMed PMID: 28739824; PubMed Central PMCID: PMCPMC5607417. DOI:10.1128/IAI.00336-17.
   PubMed Web of Science ®Google Scholar
• Sheehan G, Kavanagh K. Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans. Virulence. 2018;9(1):163–172.
   PubMed Web of Science ®Google Scholar
• Mukherjee K, Grizanova E, Chertkova E, et al. Experimental evolution of resistance against Bacillus thuringiensis in the insect model host Galleria mellonella results in epigenetic modifications. Virulence. 2017 Nov 17;8(8):1618–1630. PubMed PMID: 28521626.
   PubMed Web of Science ®Google Scholar
• Moralez AT, Perini HF, Furlaneto-Maia L, et al. Phenotypic switching of Candida tropicalis is associated with cell damage in epithelial cells and virulence in Galleria mellonella model. Virulence. 2016 May 18;7(4):379–386. PubMed PMID: 26760314; PubMed Central PMCID: PMCPMC4871662.
   PubMed Web of Science ®Google Scholar
• Krezdorn J, Adams S, Coote PJ. A Galleria mellonella infection model reveals double and triple antibiotic combination therapies with enhanced efficacy versus a multidrug-resistant strain of Pseudomonas aeruginosa. J Med Microbiol. 2014 Jul;63(Pt 7):945–955. PubMed PMID: 24928215.
   PubMed Web of Science ®Google Scholar
• Favre-Godal Q, Dorsaz S, Queiroz EF, et al. Comprehensive approach for the detection of antifungal compounds using a susceptible strain of Candida albicans and confirmation of in vivo activity with the Galleria mellonella model. Phytochemistry. 2014 Sep;105:68–78. PubMed PMID: 24984572.
   PubMed Web of Science ®Google Scholar
• Erasto P, Omolo J, Sunguruma R, et al. Evaluation of antimycobacterial activity of higenamine using Galleria mellonella as an in vivo infection model. Nat Prod Bioprospect. 2018 Feb;8(1):63–69. PubMed PMID: 29357092.
   PubMed Web of Science ®Google Scholar
• Dong CL, Li LX, Cui ZH, et al. synergistic effect of pleuromutilins with other antimicrobial agents against Staphylococcus aureus in vitro and in an experimental Galleria mellonella model. Front Pharmacol. 2017;8:553. PubMed PMID: 28874907; PubMed Central PMCID: PMCPMC5572081.
   PubMed Web of Science ®Google Scholar
• Lange A, Beier S, Huson DH, et al. Genome Sequence of Galleria mellonella (Greater Wax Moth). Genome Announc. 2018 January 11;6(2). DOI:10.1128/genomeA.01220-17
   PubMedGoogle Scholar
• Drees KP, Palmer JM, Sebra R, et al. Use of multiple sequencing technologies to produce a high-quality genome of the fungus pseudogymnoascus destructans, the causative agent of bat white-nose syndrome. Genome Announc. 2016 Jun 30;4(3):e00445-16. PubMed PMID: 27365344; PubMed Central PMCID: PMCPMC4929507.
   PubMedGoogle Scholar