AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection

References

• Brodsky IE, Monack D. NLR-Mediated control of inflammasome assembly in the host response against bacterial pathogens. Semin Immunol. 2009;21(4):199–207.
   PubMed Web of Science ®Google Scholar
• Martinon F, Mayor A, Tschopp J. The inflammasomes: guardians of the body. Annu Rev Immunol. 2009;27(1):229–265.
   PubMed Web of Science ®Google Scholar
• Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140(6):821–832.
   PubMed Web of Science ®Google Scholar
• He Y, Hara H, Nunez G. Mechanism and regulation of NLRP3 inflammasome activation. Trends Biochem Sci. 2016;41(12):1012–1021.
   PubMed Web of Science ®Google Scholar
• Dostert C, Petrilli V, Van Bruggen R, et al. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320(5876):674–677.
   PubMed Web of Science ®Google Scholar
• Gross O, Poeck H, Bscheider M, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature. 2009;459(7245):433–436. DOI:10.1038/nature07965.
   PubMed Web of Science ®Google Scholar
• Hornung V, Bauernfeind F, Halle A, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008;9(8):847–856. DOI:10.1038/ni.1631.
   PubMed Web of Science ®Google Scholar
• Kanneganti TD, Body-Malapel M, Amer A, et al. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem. 2006;281(48):36560–36568. DOI:10.1074/jbc.M607594200.
   PubMed Web of Science ®Google Scholar
• Mariathasan S, Weiss DS, Newton K, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature. 2006;440(7081):228–232. DOI:10.1038/nature04515.
   PubMed Web of Science ®Google Scholar
• Martinon F, Petrilli V, Mayor A, et al. Gout-Associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006;440(7081):237–241.
   PubMed Web of Science ®Google Scholar
• Kelley N, Jeltema D, Duan Y, et al. The NLRP3 inflammasome: an overview of mechanisms of activation and regulation. Int J Mol Sci. 2019;20(13):3328.
   PubMed Web of Science ®Google Scholar
• De Nardo D, Latz E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends Immunol. 2011;32(8):373–379.
   PubMed Web of Science ®Google Scholar
• Kuriakose T, Kanneganti TD. Regulation and functions of NLRP3 inflammasome during influenza virus infection. Mol Immunol. 2017;86:56–64.
   PubMed Web of Science ®Google Scholar
• Lupfer C, Malik A, Kanneganti TD. Inflammasome control of viral infection. Curr Opin Virol. 2015;12:38–46.
   PubMed Web of Science ®Google Scholar
• Malik G, Zhou Y. Innate immune sensing of influenza A virus. Viruses. 2020;12(7):755.
   PubMed Web of Science ®Google Scholar
• Hilleman MR. Realities and enigmas of human viral influenza: pathogenesis, epidemiology and control. Vaccine. 2002;20(25–26):3068–3087.
   PubMed Web of Science ®Google Scholar
• Potter CW. A history of influenza. J Appl Microbiol. 2001;91(4):572–579.
   PubMed Web of Science ®Google Scholar
• Reid AH, Taubenberger JK, Fanning TG. The 1918 Spanish influenza: integrating history and biology. Microbes Infect. 2001;3(1):81–87.
   PubMed Web of Science ®Google Scholar
• Li LH, Ju TC, Hsieh CY, et al. A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP. PLoS One. 2017;12(7):e0182057. DOI:10.1371/journal.pone.0182057.
   PubMed Web of Science ®Google Scholar
• Ong JD, Mansell A, Tate MD. Hero turned villain: NLRP3 inflammasome-induced inflammation during influenza A virus infection. J Leukoc Biol. 2017;101(4):863–874.
   PubMed Web of Science ®Google Scholar
• Allen IC, Scull MA, Moore CB, et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 2009;30(4):556–565. DOI:10.1016/j.immuni.2009.02.005.
   PubMed Web of Science ®Google Scholar
• Chung WC, Kang HR, Yoon H, et al. Influenza A virus NS1 protein inhibits the NLRP3 inflammasome. PLoS One. 2015;10(5):e0126456.
   PubMed Web of Science ®Google Scholar
• Ichinohe T, Pang IK, Iwasaki A. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nat Immunol. 2010;11(5):404–410.
   PubMed Web of Science ®Google Scholar
• McAuley JL, Tate MD, MacKenzie-Kludas CJ, et al. Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease. PLoS Pathog. 2013;9(5):e1003392. DOI:10.1371/journal.ppat.1003392.
   PubMed Web of Science ®Google Scholar
• Pothlichet J, Meunier I, Davis BK, et al. Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells. PLoS Pathog. 2013;9(4):e1003256. DOI:10.1371/journal.ppat.1003256.
   PubMed Web of Science ®Google Scholar
• Thomas PG, Dash P, Aldridge JR Jr., et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity. 2009;30(4):566–575. DOI:10.1016/j.immuni.2009.02.006.
   PubMed Web of Science ®Google Scholar
• Nabet B, Ob P, Reyes JM, et al. Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape. Cell Rep. 2015;12(8):1300–1313. DOI:10.1016/j.celrep.2015.06.078.
   PubMed Web of Science ®Google Scholar
• Yang SH, Sharrocks AD, Whitmarsh AJ. MAP kinase signalling cascades and transcriptional regulation. Gene. 2013;513(1):1–13.
   PubMed Web of Science ®Google Scholar
• Kidger AM, Sipthorp J, Cook SJ. ERK1/2 inhibitors: new weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway. Pharmacol Ther. 2018;187:45–60.
   PubMed Web of Science ®Google Scholar
• Meng Q, Xia Y. C-Jun, at the crossroad of the signaling network. Protein Cell. 2011;2(11):889–898.
   PubMed Web of Science ®Google Scholar
• Shaulian E, Karin M. AP-1 in cell proliferation and survival. Oncogene. 2001;20(19):2390–2400.
   PubMed Web of Science ®Google Scholar
• Fernandez-Sesma A. The influenza virus NS1 protein: inhibitor of innate and adaptive immunity. Infect Disord Drug Targets. 2007;7(4):336–343.
   PubMedGoogle Scholar
• Guarda G, Braun M, Staehli F, et al. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity. 2011;34(2):213–223. DOI:10.1016/j.immuni.2011.02.006.
   PubMed Web of Science ®Google Scholar
• Rajan JV, Rodriguez D, Miao EA, et al. The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. J Virol. 2011;85(9):4167–4172.
   PubMed Web of Science ®Google Scholar
• Wang H, Lei X, Xiao X, et al. Reciprocal regulation between enterovirus 71 and the NLRP3 inflammasome. Cell Rep. 2015;12(1):42–48. DOI:10.1016/j.celrep.2015.05.047.
   PubMed Web of Science ®Google Scholar
• Wang W, Xiao F, Wan P, et al. EV71 3D protein binds with NLRP3 and enhances the assembly of inflammasome complex. PLoS Pathog. 2017;13(1):e1006123. DOI:10.1371/journal.ppat.1006123.
   PubMed Web of Science ®Google Scholar
• da Costa LS, Outlioua A, Anginot A, et al. RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux. Cell Death Amp Dis. 2019;10(5):346.
   PubMedGoogle Scholar
• Cheung PH, Ye ZW, Lee TT, et al. PB1-F2 protein of highly pathogenic influenza A (H7N9) virus selectively suppresses RNA-induced NLRP3 inflammasome activation through inhibition of MAVS-NLRP3 interaction. J Leukoc Biol. 2020;108(5):1655–1663.
   PubMed Web of Science ®Google Scholar
• Kuriakose T, Man SM, Malireddi RK, et al. ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways. Sci Immunol. 2016;1(2). DOI:10.1126/sciimmunol.aag2045.
   PubMed Web of Science ®Google Scholar
• Kuriakose T, Zheng M, Neale G, et al. IRF1 is a transcriptional regulator of ZBP1 promoting NLRP3 inflammasome activation and cell death during influenza virus infection. J Immunol. 2018;200(4):1489–1495.
   PubMed Web of Science ®Google Scholar
• Liu CC, Miao Y, Chen RL, et al. STIM1 mediates IAV-induced inflammation of lung epithelial cells by regulating NLRP3 and inflammasome activation via targeting miR-223. Life Sci. 2021;266:118845.
   PubMed Web of Science ®Google Scholar
• Momota M, Lelliott P, Kubo A, et al. ZBP1 governs the inflammasome-independent IL-1α and neutrophil inflammation that play a dual role in anti-influenza virus immunity. Int Immunol. 2020;32(3):203–212. DOI:10.1093/intimm/dxz070.
   PubMed Web of Science ®Google Scholar
• Park HS, Liu G, Thulasi Raman SN, et al. NS1 protein of 2009 pandemic influenza A virus inhibits Porcine NLRP3 inflammasome-mediated interleukin-1 Beta production by suppressing ASC ubiquitination. J Virol. 2018;92(8). DOI:10.1128/JVI.00022-18
   Web of Science ®Google Scholar
• Kyriakis JM, Avruch J. Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. Physiol Rev. 2012;92(2):689–737.
   PubMed Web of Science ®Google Scholar
• Jin X, Wang C, Wu W, et al. Cyanidin-3-Glucoside alleviates 4-hydroxyhexenal-induced NLRP3 inflammasome activation via JNK-c-Jun/AP-1 pathway in human retinal pigment epithelial cells. J Immunol Res. 2018;2018:5604610.
   PubMed Web of Science ®Google Scholar
• Chen XX, Guo Z, Jin Q, et al. Porcine reproductive and respiratory syndrome virus induces interleukin-1beta through MyD88/ERK/AP-1 and NLRP3 inflammasome in microglia. Vet Microbiol. 2018;227:82–89.
   PubMed Web of Science ®Google Scholar
• Fann DY, Lim YA, Cheng YL, et al. Evidence that NF-κB and MAPK signaling promotes NLRP inflammasome activation in neurons following ischemic stroke. Mol Neurobiol. 2018;55(2):1082–1096. DOI:10.1007/s12035-017-0394-9.
   PubMed Web of Science ®Google Scholar