Evaluation of the immunogenicity of auxotrophic Lactobacillus with CRISPR-Cas9D10A system-mediated chromosomal editing to express porcine rotavirus capsid protein VP4

References

• Clark HF, Burke CJ, Volkin DB, et al. Safety, immunogenicity and efficacy in healthy infants of G1 and G2 human reassortant rotavirus vaccine in a new stabilizer/buffer liquid formulation. Pediatr Infect Dis J. 2003;22(10):914–920. DOI:10.1097/01.inf.0000091887.48999.77
   PubMed Web of Science ®Google Scholar
• Hideaki S, Takashi W , Shinji F, et al. A novel mucosal vaccine targeting Peyer’s patch M cells induces protective antigen-specific IgA responses. A novel mucosal vaccine targeting Peyer’s patch M cells induces protective antigen-specific IgA responses. International Immunology. 2014;(11):619–625.
   PubMed Web of Science ®Google Scholar
• Ho PS, Kwang J, Lee YKJV. Intragastric administration of Lactobacillus casei expressing transmissible gastroentritis coronavirus spike glycoprotein induced specific antibody production. Vaccine. 2005;23(11):1335–1342.
   PubMed Web of Science ®Google Scholar
• Yin JY, Guo C-Q, Wang Z, et al. Directed chromosomal integration and expression of porcine rotavirus outer capsid protein VP4 in Lactobacillus casei ATCC393. Appl Microbiol Biotechnol. 2016;100(22):1–12. DOI:10.1007/s00253-016-7779-y
   PubMed Web of Science ®Google Scholar
• Pouwels PH, Leer RJ, Boersma WJJOB. The potential of Lactobacillus as a carrier for oral immunization: Development and preliminary characterization of vector systems for targeted delivery of antigens. J Biotechnol. 1996;44(1–3):183.
   PubMed Web of Science ®Google Scholar
• Gibson GR, Probert HM, Loo JV, et al. Dietary modulation of the human colonic microbiota: Updating the concept of prebiotics. Nutr Res Rev. 2004;17(2):259–275. DOI:10.1079/NRR200479
   PubMed Web of Science ®Google Scholar
• Davies FL, Gasson MJJJODR. Genetics of lactic acid bacteria. J Dairy Res. 1981;48(2):363–376.
   PubMed Web of Science ®Google Scholar
• Hugenholtz J, Smid EJJCOIB. Nutraceutical production with food-grade microorganisms. 2002;13(5):497–507. DOI:10.1016/s0958-1669(02)00367-1.
   Google Scholar
• Jingqi Zhao,Ting Yan,Yaqi Wang, et al. Lactobacillus plantarum BC299 can alleviate dextran sulphate sodium-induced colitis by regulating immune response and modulating gut microbiota. Int J Food Sci Technol. 2021; 56(11):5698–5707.
   Web of Science ®Google Scholar
• Chen Y, Liu S, Yu C, et al. Evaluating the effectiveness of Lactobacillus zeae against enterotoxigenic Escherichia coli F4 infection in an in vitro porcine intestinal epithelial cell model. 2021.
   Google Scholar
• Dogi CA, Galdeano CM, Perdigón G. Gut immune stimulation by non pathogenic Gram(+) and Gram(-) bacteria. Comparison with a probiotic strain. Cytokine. 2008;41(3):223–231.
   PubMed Web of Science ®Google Scholar
• Galdeano CM, De Moreno De Leblanc A, Vinderola G, et al. Proposed model: Mechanisms of immunomodulation induced by probiotic bacteria. Clin Vaccin Immunol. 2007;14(5):485–492. DOI:10.1128/CVI.00406-06
   PubMed Web of Science ®Google Scholar
• LU Wenwei, Z Yang, L Ding, et al. Evaluation of intestinal microbiota in mice after oral administration of lactobacillus paracasei LC01. Food Sci. 2016.
   Google Scholar
• Vidal K, Benyacoub J, Moser M, et al. Effect of Lactobacillus paracasei NCC2461 on antigen-specific T-cell mediated immune responses in aged mice. Rejuvenation Res. 2008;11(5):957. DOI:10.1089/rej.2008.0780
   PubMed Web of Science ®Google Scholar
• O“sullivan DJ, Klaenhammer TRJG. High- and low-copy-number Lactococcus shuttle cloning vectors with features for clone screening. Gene. 1993;137(2):227–231.
   PubMed Web of Science ®Google Scholar
• Pouwels PHJAEM. Incompatibility of Lactobacillus vectors with replicons derived from small cryptic lactobacillus plasmids and segregational instability of the introduced vectors. Appl Environ Microbiol. 1991;19(1):28.
   Web of Science ®Google Scholar
• Lu WW, Wang T, Wang Y, et al. A food-grade fimbrial adhesin FaeG expression system in Lactococcus lactis and Lactobacillus casei. Can J Microbiol. 2016;62(3):241–248. DOI:10.1139/cjm-2015-0596
   PubMed Web of Science ®Google Scholar
• Bron PA Benchimol M G, Lambert J, et al. Use of the alr Gene as a Food-Grade Selection Marker in Lactic Acid Bacteria. Appl Environ Microbiol. 2002;68(11):5663–5670. DOI:10.1128/AEM.68.11.5663-5670.2002
   PubMed Web of Science ®Google Scholar
• Zajdowicz SLW, Jones-Carson J, Vazquez-Torres A, et al. Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. PLoS One. 2011;6(6):e21523. DOI:10.1371/journal.pone.0021523
   PubMed Web of Science ®Google Scholar
• Hols P, Defrenne C, Ferain T, et al. The alanine racemase gene is essential for growth of Lactobacillus plantarum. J Bacteriol. 1997;179(11):3804–3807. DOI:10.1128/jb.179.11.3804-3807.1997
   PubMed Web of Science ®Google Scholar
• Liu Q, Jiang Y, and Yang W, et al. Protective effects of a food-grade recombinant Lactobacillus plantarum with surface displayed AMA1 and EtMIC2 proteins of Eimeria tenella in broiler chickens. Microbial Cell Factories. 2020;19(1):11-28.
   Web of Science ®Google Scholar
• Pham ML, Tran A-M, and Mathiesen G, et al. Cell wall anchoring of a bacterial chitosanase in lactobacillus plantarum using a food-grade expression system and two versions of an LP TG anchor. International Journal of Molecular Sciences. 2020;21(11):3773. DOI:10.3390/ijms21113773
   PubMed Web of Science ®Google Scholar
• Ehrlich SD, Bruand C, Sozhamannan S, et al. Plasmid replication and structural stability in Bacillus subtilis. Res Microbiol. 1991;142(7–8):869–873. DOI:10.1016/0923-2508(91)90067-K
   PubMed Web of Science ®Google Scholar
• Bidart GN, Rodríguez-Díaz J, Monedero V, et al. A unique gene cluster for the utilization of the mucosal and human milk-associated glycans galacto- N -biose and lacto- N -biose in L actobacillus casei. Mol Microbiol. 2014;93(3):521–538. DOI:10.1111/mmi.12678
   PubMed Web of Science ®Google Scholar
• Jan-Peter VP, and Britton RAJNAR. High efficiency recombineering in lactic acid bacteria. Nucleic Acids Research. 2012(10):e76.
   Google Scholar
• Pijkeren J, Britton RAJMCF. Precision genome engineering in lactic acid bacteria. Microb Cell Fact. 2014;13(1):S10.
   PubMedGoogle Scholar
• Hille, Hille F, Richter H, et al. The biology of CRISPR-cas: Backward and forward. Cell. 2018;172(6):1239–1259. DOI:10.1016/j.cell.2017.11.032
   PubMed Web of Science ®Google Scholar
• Liu C, Zhang L, and Liu H, et al. Delivery strategies of the CRISPR-cas9 gene-editing system for therapeutic applications. Journal of Controlled Release. 2017;17–26.
   PubMed Web of Science ®Google Scholar
• Eugene Koonin EV, Makarova KS, et al. Origins and evolution of CRISPR-cas systems. Philosophical Transactions of the Royal Society of; 2019.
   Google Scholar
• Jiang W, Bikard D, Cox D, et al. RNA-Guided editing of bacterial genomes using CRISPR-cas systems. Nat Biotechnol. 2013;31(3):233–239. DOI:10.1038/nbt.2508
   PubMed Web of Science ®Google Scholar
• Jee-Hwan O, van P-J-P-J-N-A. Research, CRISPR–Cas9-assisted recombineering in Lactobacillus reuteri. Nucleic Acids Res. 2014(17):e131.
   Google Scholar
• Barrangou R, Fremaux C, Deveau H, et al. CRISPR provides acquired resistance against viruses in prokaryotes. Science. 2007;315(5819):1709–1712. DOI:10.1126/science.1138140
   PubMed Web of Science ®Google Scholar
• Xin Song, He Huang, Zhiqiang Xiong, et al. CRISPR-Cas9d10a nickase-assisted genome editing in Lactobacillus casei. Appl Environ Microbiol. 2017;83(22):01259–17.
   Web of Science ®Google Scholar
• Diaz-Salinas MA, Romero P, Espinosa R, et al. The spike protein VP4 defines the endocytic pathway used by rotavirus to enter MA104 cells. J Virol. 2013;87(3):1658–63. doi:10.1128/JVI.02086-12.
   PubMed Web of Science ®Google Scholar
• Liu X, Zhang GM, Li HZJCJOB. Passive immune protection of neonatal mice with recombinant adenovirus expressing rotavirus VP4 antigen. Vet Microbiol. 2007;20(1):33–36.
   Google Scholar
• YH Zhang, HU Huai-Rong, XY Xian, et al. Isolation and Identification of Lactic Acid Bacteria from Intestinal Tract of Rongchang Pig. J Southwest Univ(Natural). 2016.
   Google Scholar
• Wang L, Xia T, Guo T, et al. Recombinant lactobacillus casei expressing capsid protein vp60 can serve as vaccine against rabbit hemorrhagic disease virus in rabbits. Vet Microbiol. 2019;7(4).
   Google Scholar
• Meiling Y, Wang L, Ma S, et al. immunogenicity of egfp-marked recombinant lactobacillus casei against transmissible gastroenteritis virus and porcine epidemic diarrhea virus. Viruses. 2017;9(10):274. DOI:10.3390/v9100274
   PubMed Web of Science ®Google Scholar
• Liu D, Wang X, Ge J, et al. Comparison of the immune responses induced by oral immunization of mice with Lactobacillus casei-expressing porcine parvovirus VP2 and VP2 fused to Escherichia coli heat-labile enterotoxin B subunit protein. Comp Immunol Microbiol. 2011;34(1):73–81. DOI:10.1016/j.cimid.2010.02.004
   PubMed Web of Science ®Google Scholar
• Xiaona W, Wang L, Huang X, et al. Oral delivery of probiotics expressing dendritic cell-targeting peptide fused with porcine epidemic diarrhea virus coe antigen: A promising vaccine strategy against PEDV. Viruses. 2017;9(11):312. DOI:10.3390/v9110312
   PubMed Web of Science ®Google Scholar
• Qiao X, Li G, Wang X, et al. Recombinant porcine rotavirus VP4 and VP4-LTB expressed in Lactobacillus casei induced mucosal and systemic antibody responses in mice. BMC Microbiol. 2009;9(1):249. DOI:10.1186/1471-2180-9-249
   PubMedGoogle Scholar
• Hou X, Jiang X, Jiang Y, et al. Oral immunization against PEDV with recombinant Lactobacillus casei expressing dendritic cell-targeting peptide fusing COE protein of PEDV in Piglets. BMC Microbiol. 2018;10(3):106.
   Google Scholar
• Gao X, Ma Y, Wang Z, et al. Oral immunization of mice with a probiotic Lactobacillus casei constitutively expressing the α-toxoid induces protective immunity against Clostridium perfringens α-toxin. Virulence. 2019;10(1):166–179. DOI:10.1080/21505594.2019.1582975
   PubMed Web of Science ®Google Scholar
• Xu T, Li Y, Shi Z, et al. Efficient genome editing in clostridium cellulolyticum via CRISPR-cas9 nickase. Appl Environ Microbiol. 2015;81(13):4423–4431. DOI:10.1128/AEM.00873-15
   PubMed Web of Science ®Google Scholar
• Ran F, Hsu P, Lin C-Y, et al. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 2013;154(6):1380–1389. DOI:10.1016/j.cell.2013.08.021
   PubMed Web of Science ®Google Scholar
• Wild J, Hennig J, Lobocka M, et al. Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12. Mol Gen Genet. 1985;198(2):315–322. DOI:10.1007/BF00383013
   PubMedGoogle Scholar
• Bron PA, Hoffer SM, Van Swam II, et al. Selection and characterization of conditionally active promoters in Lactobacillus plantarum, using alanine racemase as a promoter probe. Molecular & General Genetics Mgg. 2004;70(1):310–317.
   Google Scholar
• Guan Wang, Mingyue Hao, Qiong Liu, et al. Protective effect of recombinant Lactobacillus plantarum against H 2 O 2 -induced oxidative stress in HUVEC cells. J Zhejiang Univ Sci B. 2021;22(5):348–365.
   PubMed Web of Science ®Google Scholar
• Ying L, Deng ZL, Zhang ZS, et al. A novel expression vector for Corynebacterium glutamicum with an auxotrophy complementation system. ScienceDirect. Chin Med J (Engl). 1994;107(3):171–175.
   PubMedGoogle Scholar
• Offit PA, Shaw RD, Greenberg HBJJOV. Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to surface proteins vp3 and vp7. J Virol. 1986;58(2):700–703.
   PubMed Web of Science ®Google Scholar
• Li YJ, Ma G-P, Li G-W, et al. Oral Vaccination with the porcine rotavirus VP4 outer capsid protein expressed by Lactococcus lactis induces specific antibody production. J Biomed Biotechnol. 2010;2010(3):708460. DOI:10.1155/2010/708460
   PubMedGoogle Scholar
• Jiang X, Yu M, Qiao X, et al. Up-Regulation of MDP and tuftsin gene expression in Th1 and Th17 cells as an adjuvant for an oral Lactobacillus casei vaccine against anti-transmissible gastroenteritis virus. Science. 1940;91(19):554–555. DOI:10.1126/science.91.2371.554
   PubMedGoogle Scholar
• Sutherland DB, Fagarasan SJCOII. IgA synthesis: A form of functional immune adaptation extending beyond gut. Appl Microbiol Biotechnol. 2012;24(3):261–268.
   Google Scholar
• Holmgren J, Czerkinsky CJNM. Mucosal immunity and vaccines. Nat Med. 2005;11(Suppl 4):S45–S53.
   PubMed Web of Science ®Google Scholar
• Macpherson AJ, McCoy K D, and Johansen F-E, et al. The immune geography of IgA induction and function. Mucosal Immunology. 2008;1(1):11–22. DOI:10.1038/mi.2007.6
   PubMed Web of Science ®Google Scholar
• Mantis NJ, Rol N, Corthésy BJMI. Secretory IgA’s complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunol. 2011;4(6):603.
   PubMed Web of Science ®Google Scholar
• SH Shi, WT Yang, GL Yang, et al. Lactobacillus plantarum vaccine vector expressing hemagglutinin provides protection against H9N2 challenge infection. Virus Research, 2016. 211.
   Google Scholar
• Ma S, Wang Li, Huang X, et al. Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine epidemic diarrhea virus. Microb Cell Fact. 2018;17(1):20. DOI:10.1186/s12934-018-0861-7
   PubMed Web of Science ®Google Scholar
• Fagarasan, Fagarasan S, Kawamoto S, et al. Adaptive immune regulation in the Gut: T cell–Dependent and T cell–Independent IgA synthesis. Annu Rev Immunol. 2010;28(1):243–273. DOI:10.1146/annurev-immunol-030409-101314
   PubMedGoogle Scholar