Role of aggregate-forming pilus (AFP) in adherence and colonization of both intestinal and urinary tracts

References

• Santos ACM, Santos FF, Silva RM, et al. Diversity of hybrid- and hetero-pathogenic Escherichia coli and their potential implication in more severe diseases. Front Cell Infect Microbiol. 2020;10:339. DOI:10.3389/fcimb.2020.00339.
   PubMed Web of Science ®Google Scholar
• Abe CM, Salvador FA, Falsetti IN, et al. Uropathogenic Escherichia coli (UPEC) strains may carry virulence properties of diarrhoeagenic E. coli. FEMS Immunol Med Microbiol. 2008;52(3):397–406. DOI:10.1111/j.1574-695X.2008.00388.x.
   PubMedGoogle Scholar
• Flament-Simon SC, Nicolas-Chanoine MH, García V, et al. Clonal structure, virulence factor-encoding genes and antibiotic resistance of Escherichia coli, causing urinary tract infections and other extraintestinal infections in humans in Spain and France during 2016. Antibiotics (Basel). 2020;9(4):161. DOI:10.3390/antibiotics9040161.
   PubMed Web of Science ®Google Scholar
• Lara FB, Nery DR, de Oliveira PM, et al. Virulence markers and phylogenetic analysis of Escherichia coli strains with hybrid EAEC/UPEC genotypes recovered from sporadic cases of extraintestinal infections. Front Microbiol. 2017;8:146. DOI:10.3389/fmicb.2017.00146.
   PubMed Web of Science ®Google Scholar
• Nascimento JAS, Santos FF, Valiatti TB, et al. Frequency and diversity of hybrid Escherichia coli strains isolated from urinary tract infections. Microorganisms. 2021;9(4):693. DOI:10.3390/microorganisms9040693.
   PubMed Web of Science ®Google Scholar
• Nunes KO, Santos ACP, Bando SY, et al. Enteroaggregative Escherichia coli with uropathogenic characteristics are present in feces of diarrheic and healthy children. Pathog Dis. 2017;75(8):10.1093/femspd/ftx106. DOI:10.1093/femspd/ftx106.
   PubMed Web of Science ®Google Scholar
• Schüroff PA, Salvador FA, Abe CM, et al. The aggregate-forming pili (AFP) mediates the aggregative adherence of a hybrid-pathogenic Escherichia coli (UPEC/EAEC) isolated from a urinary tract infection. Virulence. 2021;12(1):3073–3093. DOI:10.1080/21505594.2021.2007645.
   PubMed Web of Science ®Google Scholar
• Tanabe RHS, Dias RCB, Orsi H, et al. Characterization of uropathogenic Escherichia coli reveals hybrid isolates of uropathogenic and diarrheagenic (UPEC/DEC) E. coli. Microorganisms. 2022;10(3):645. DOI:10.3390/microorganisms10030645.
   PubMed Web of Science ®Google Scholar
• Toval F, Köhler CD, Vogel U, et al. Characterization of Escherichia coli isolates from hospital inpatients or outpatients with urinary tract infection. J Clin Microbiol. 2014;52(2):407–418. DOI:10.1128/JCM.02069-13.
   PubMed Web of Science ®Google Scholar
• Lang C, Fruth A, Holland G, et al. Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence. Emerg Microbes Infect. 2018;7(1):203. DOI:10.1038/s41426-018-0209-8.
   PubMed Web of Science ®Google Scholar
• Dias RCB, Tanabe RHS, Vieira MA, et al. Analysis of the virulence profile and phenotypic features of typical and atypical enteroaggregative Escherichia coli (EAEC) isolated from diarrheal patients in Brazil. Front Cell Infect Microbiol. 2020;10:144. DOI:10.3389/fcimb.2020.00144.
   PubMed Web of Science ®Google Scholar
• Datsenko KA, Wanner BL One-Step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA. 2000;97(12):6640–6645. DOI:10.1073/pnas.120163297.
   PubMed Web of Science ®Google Scholar
• Schembri MA, Blom J, Krogfelt KA, et al. Capsule and fimbria interaction in Klebsiella pneumoniae. Infect Immun. 2005;73(8):4626–4633. DOI:10.1128/IAI.73.8.4626-4633.2005.
   PubMed Web of Science ®Google Scholar
• Harrington SM, Sheikh J, Henderson IR, et al. The Pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucin. Infect Immun. 2009;77(6):2465–2473. DOI:10.1128/IAI.01494-08.
   PubMed Web of Science ®Google Scholar
• Boll EJ, Struve C, Boisen N, et al. Role of enteroaggregative Escherichia coli virulence factors in uropathogenesis. Infect Immun. 2013;81(4):1164–1171. DOI:10.1128/IAI.01376-12.
   PubMed Web of Science ®Google Scholar
• Knutton S Electron microscopical methods in adhesion. Methods Enzymol. 1995;253:145–158. DOI:10.1016/s0076-6879(95)53015-0.
   PubMed Web of Science ®Google Scholar
• Lüthje P, Brauner A Virulence factors of uropathogenic E. coli and their interaction with the host. Adv Microb Physiol. 2014;65:337–372. DOI:10.1016/bs.ampbs.2014.08.006.
   PubMed Web of Science ®Google Scholar
• Terlizzi ME, Gribaudo G, Maffei ME UroPathogenic Escherichia coli (UPEC) infections: virulence factors, bladder responses, antibiotic, and non-antibiotic antimicrobial strategies. Front Microbiol. 2017;8:1566. DOI:10.3389/fmicb.2017.01566.
   PubMed Web of Science ®Google Scholar
• Lewis AJ, Richards AC, Mulvey MA Invasion of host cells and tissues by uropathogenic bacteria. Microbiol Spectr. 2016;4(6). DOI:10.1128/microbiolspec.UTI-0026-2016
   Web of Science ®Google Scholar
• Owrangi B, Masters N, Kuballa A, et al. Invasion and translocation of uropathogenic Escherichia coli isolated from urosepsis and patients with community-acquired urinary tract infection. Eur J Clin Microbiol Infect Dis. 2018;37(5):833–839. DOI:10.1007/s10096-017-3176-4.
   PubMed Web of Science ®Google Scholar
• Valiatti TB, Santos FF, Santos ACM, et al. Genetic and virulence characteristics of a hybrid atypical enteropathogenic and uropathogenic Escherichia coli (aEPEC/UPEC) strain. Front Cell Infect Microbiol. 2020;10:492. DOI:10.3389/fcimb.2020.00492.
   PubMed Web of Science ®Google Scholar
• Aguiniga LM, Yaggie RE, Schaeffer AJ, et al. Lipopolysaccharide domains modulate urovirulence. Infect Immun. 2016;84(11):3131–3140. DOI:10.1128/IAI.00315-16.
   PubMed Web of Science ®Google Scholar
• Hadjifrangiskou M, Gu AP, Pinkner JS, et al. Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors. J Bacteriol. 2012;194(22):6195–6205. DOI:10.1128/JB.01012-12.
   PubMed Web of Science ®Google Scholar
• Li J, Wang N Genome-Wide mutagenesis of Xanthomonas axonopodis pv. citri reveals novel genetic determinants and regulation mechanisms of biofilm formation. PLoS One. 2011;6(7):e21804. DOI:10.1371/journal.pone.0021804.
   PubMed Web of Science ®Google Scholar
• Mireles JR 2nd, Toguchi A, Harshey RM Salmonella enterica serovar typhimurium swarming mutants with altered biofilm-forming abilities: surfactin inhibits biofilm formation. J Bacteriol. 2001;183(20):5848–5854. DOI:10.1128/JB.183.20.5848-5854.2001.
   PubMed Web of Science ®Google Scholar
• Moreira CG, Carneiro SM, Nataro JP, et al. Role of type I fimbriae in the aggregative adhesion pattern of enteroaggregative Escherichia coli. FEMS Microbiol Lett. 2003;226(1):79–85. DOI:10.1016/S0378-1097(03)00561-5.
   PubMed Web of Science ®Google Scholar
• Melican K, Sandoval RM, Kader A, et al. Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction. PLoS Pathog. 2011;7(2):e1001298. DOI:10.1371/journal.ppat.1001298.
   PubMed Web of Science ®Google Scholar
• Tseng CC, Lin WH, Wu AB, et al. Escherichia coli FimH adhesins act synergistically with PapGII adhesins for enhancing establishment and maintenance of kidney infection. J Microbiol Immunol Infect. 2022;55(1):44–50. DOI:10.1016/j.jmii.2020.09.001.
   PubMedGoogle Scholar
• Abreu AG, Abe CM, Nunes KO, et al. The serine protease Pic as a virulence factor of atypical enteropathogenic Escherichia coli. Gut Microbes. 2016;7(2):115–125. DOI:10.1080/19490976.2015.1136775.
   PubMed Web of Science ®Google Scholar
• Sarkar S, Hutton ML, Vagenas D, et al. Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131. J Infect Dis. 2018;218(6):979–990. DOI:10.1093/infdis/jiy031.
   PubMed Web of Science ®Google Scholar
• Spaulding CN, Klein RD, Ruer S, et al. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist. Nature. 2017;546(7659):528–532. DOI:10.1038/nature22972.
   PubMed Web of Science ®Google Scholar
• Spaulding CN, Schreiber HL 4th, Zheng W, et al. Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions. Elife. 2018;7:e31662. DOI:10.7554/eLife.31662.
   PubMed Web of Science ®Google Scholar
• Meador JP, Caldwell ME, Cohen PS, et al. Escherichia coli pathotypes occupy distinct niches in the mouse intestine. Infect Immun. 2014;82(5):1931–1938. DOI:10.1128/IAI.01435-13.
   PubMed Web of Science ®Google Scholar
• Hebbelstrup Jensen B, Olsen KE, Struve C, et al. Epidemiology and clinical manifestations of enteroaggregative Escherichia coli. Clin Microbiol Rev. 2014;27(3):614–630. DOI:10.1128/CMR.00112-13.
   PubMed Web of Science ®Google Scholar
• Köhler CD, Dobrindt U What defines extraintestinal pathogenic Escherichia coli? Int J Med Microbiol. 2011;301(8):642–647. DOI:10.1016/j.ijmm.2011.09.006.
   PubMed Web of Science ®Google Scholar
• Wright KJ, Seed PC, Hultgren SJ Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol. 2007;9(9):2230–2241. DOI:10.1111/j.1462-5822.2007.00952.x.
   PubMed Web of Science ®Google Scholar
• Forsyth VS, Armbruster CE, Smith SN, et al. Rapid growth of uropathogenic Escherichia coli during human urinary tract infection. Mbio. 2018;9(2):e00186–18. DOI:10.1128/mBio.00186-18.
   PubMed Web of Science ®Google Scholar
• Binns MM, Davies DL, Hardy KG Cloned fragments of the plasmid ColV,I-K94 specifying virulence and serum resistance. Nature. 1979;279(5716):778–781. DOI:10.1038/279778a0.
   PubMed Web of Science ®Google Scholar
• Biran D, Rosenshine I, Ron EZ Escherichia coli O-antigen capsule (group 4) is essential for serum resistance. Res Microbiol. 2020;171(2):99–101. DOI:10.1016/j.resmic.2019.12.002.
   PubMed Web of Science ®Google Scholar