Cathepsin gene expression in abdominal subcutaneous adipose tissue of obese/overweight humans

References

• Blüher M. Adipose tissue dysfunction in obesity. Exp Clin Endocrinol Diabetes. 2009;117(6):241–250.
   PubMed Web of Science ®Google Scholar
• Nunez C, Rodrigues VS, Gomes FS, et al. Defective regulation of adipose tissue autophagy in obesity. Int J Obesity. 2013;37(11):1473.
   Web of Science ®Google Scholar
• Soussi H, Reggio S, R Alili, et al. DAPK2 down-regulation associates with attenuated adipocyte autophagic clearance in human obesity. Diabetes. 2015;64(10):3452–3463.
   PubMed Web of Science ®Google Scholar
• Xu Q, Mariman ECM, Roumans NJT, et al. Adipose tissue autophagy related gene expression is associated with glucometabolic status in human obesity. Adipocyte. 2018;7(1):12–19.
   PubMed Web of Science ®Google Scholar
• Fujiwara Y, Wada K, Kabuta T. Lysosomal degradation of intracellular nucleic acids—multiple autophagic pathways. J Biochem. 2016;161(2):145–154.
   Web of Science ®Google Scholar
• Meijer AJ, Codogno P. Regulation and role of autophagy in mammalian cells. Int J Biochem Cell Biol. 2004;36(12):2445–2462.
   PubMed Web of Science ®Google Scholar
• Araujo TF, Cordeiro AV, Vasconcelos DAA, et al. The role of cathepsin B in autophagy during obesity: a systematic review. Life Sci. 2018;209:274–281.
   PubMed Web of Science ®Google Scholar
• Kaminskyy V, Zhivotovsky B. Proteases in autophagy. Biochim Biophys Acta. 2012;1824(1):44–50.
   PubMed Web of Science ®Google Scholar
• Mizunoe Y, Sudo Y, Okita N, et al. Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. Autophagy. 2017;13(4):642–653.
   PubMed Web of Science ®Google Scholar
• Most J, Timmers S, Warnke I, et al. Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial, 2. Am J Clin Nutr. 2016;104(1):215–227.
   PubMed Web of Science ®Google Scholar
• Rao X, Huang X, Zhou Z, et al. An improvement of the 2ˆ (–delta delta CT) method for quantitative real-time polymerase chain reaction data analysis. Biostat Bioinforma Biomath. 2013;3(3):71.
   PubMedGoogle Scholar
• Most J, Goossens GH, Reijnders D, et al. Gut microbiota composition strongly correlates to peripheral insulin sensitivity in obese men but not in women. Benef Microbes. 2017;8(4):557–562.
   PubMed Web of Science ®Google Scholar
• Reijnders D, Goossens G, Hermes GA, et al. Effects of gut microbiota manipulation by antibiotics on host metabolism in obese humans: a randomized double-blind placebo-controlled trial. Cell Metab. 2016;24(1):63–74.
   PubMed Web of Science ®Google Scholar
• Matthews D, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–419.
   PubMed Web of Science ®Google Scholar
• Kotronen A, Seppälä-Lindroos A, Bergholm R, et al. Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome. Diabetologia. 2008;51(1):130–138.
   PubMed Web of Science ®Google Scholar
• Brehm A, Krssak M, Schmid AI, et al. Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes. 2006;55(1):136–140.
   PubMed Web of Science ®Google Scholar
• Jocken JW, Langin D, Smit E, et al. Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. J Clin Endocrinol Metab. 2007;92(6):2292–2299.
   PubMed Web of Science ®Google Scholar
• Turk V, Stoka V, Vasiljeva O, et al. Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim Biophys Acta. 2012;1824(1):68–88.
   PubMed Web of Science ®Google Scholar
• Mizunoe Y, Kobayashi M, Hoshino S, et al. Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes. Sci Rep. 2020;10(1):1–12.
   PubMed Web of Science ®Google Scholar
• González-Muniesa P, Marrades M, Martínez J, et al. Differential proinflammatory and oxidative stress response and vulnerability to metabolic syndrome in habitual high-fat young male consumers putatively predisposed by their genetic background. Int J Mol Sci. 2013;14(9):17238–17255.
   PubMed Web of Science ®Google Scholar
• Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest. 2000;106(4):473–481.
   PubMed Web of Science ®Google Scholar
• Bagherniya M, Butler AE, Barreto GE, et al. The effect of fasting or calorie restriction on autophagy induction: A review of the literature. Ageing Res Rev. 2018;47:183–197.
   PubMed Web of Science ®Google Scholar
• Kim KH, Jeong YT, Oh H, et al. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med. 2013;19(1):83.
   PubMed Web of Science ®Google Scholar
• Feldstein AE, Werneburg NW, Canbay A, et al. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-α expression via a lysosomal pathway. Hepatology. 2004;40(1):185–194.
   PubMed Web of Science ®Google Scholar
• Ding L, Goossens GH, Oligschlaeger Y, et al. Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans. Diabetologia. 2020;63(2):374–384.
   PubMed Web of Science ®Google Scholar
• van Niekerk G, Du Toit A, Loos B, et al. Nutrient excess and autophagic deficiency: explaining metabolic diseases in obesity. Metabolism. 2018;82:14–21.
   PubMed Web of Science ®Google Scholar