Rehmannia glutinosa polysaccharide induces toll-like receptor 4 dependent spleen dendritic cell maturation and anti-cancer immunity

References

• Jin JO, Zhang W, Du JY, Wong KW, Oda T, Yu Q. Fucoidan can function as an adjuvant in vivo to enhance dendritic cell maturation and function and promote antigen-specific T cell immune responses. PloS One 2014; 9:e99396; PMID:24911024; https://doi.org/10.1371/journal.pone.0099396
   PubMed Web of Science ®Google Scholar
• Luo M, Shao B, Nie W, Wei XW, Li YL, Wang BL, He ZY, Liang X, Ye TH, Wei YQ. Antitumor and adjuvant activity of lambda-carrageenan by stimulating immune response in cancer immunotherapy. Sci Rep 2015; 5:11062; PMID:26098663; https://doi.org/10.1038/srep11062
   PubMed Web of Science ®Google Scholar
• Zhang W, Du JY, Jiang Z, Okimura T, Oda T, Yu Q, Jin JO. Ascophyllan purified from Ascophyllum nodosum induces Th1 and Tc1 immune responses by promoting dendritic cell maturation. Mar Drugs 2014; 12:4148-64; PMID:25026264; https://doi.org/10.3390/md12074148
   PubMed Web of Science ®Google Scholar
• Huang Y, Jiang C, Hu Y, Zhao X, Shi C, Yu Y, Liu C, Tao Y, Pan H, Feng Y et al. Immunoenhancement effect of rehmannia glutinosa polysaccharide on lymphocyte proliferation and dendritic cell. Carbohydr Polym 2013; 96:516-21; PMID:23768595; https://doi.org/10.1016/j.carbpol.2013.04.018
   PubMed Web of Science ®Google Scholar
• Zhang Z, Meng Y, Guo Y, He X, Liu Q, Wang X, Shan F. Rehmannia glutinosa polysaccharide induces maturation of murine bone marrow derived Dendritic cells (BMDCs). Int J Biol Macromol 2013; 54:136-43; PMID:23246902; https://doi.org/10.1016/j.ijbiomac.2012.12.005
   PubMed Web of Science ®Google Scholar
• Huang Y, Liu Z, Bo R, Xing J, Luo L, Zhen S, Niu Y, Hu Y, Liu J, Wu Y et al. The enhanced immune response of PCV-2 vaccine using Rehmannia glutinosa polysaccharide liposome as an adjuvant. Int J Biol Macromol 2016; 86:929-36; PMID:26851361; https://doi.org/10.1016/j.ijbiomac.2016.02.003
   PubMed Web of Science ®Google Scholar
• Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392:245-52; PMID:9521319; https://doi.org/10.1038/32588
   PubMed Web of Science ®Google Scholar
• Dubensky TW, Jr, Reed SG. Adjuvants for cancer vaccines. Semin Immunol 2010; 22:155-61; PMID:20488726; https://doi.org/10.1016/j.smim.2010.04.007
   PubMed Web of Science ®Google Scholar
• Moser M, Murphy KM. Dendritic cell regulation of TH1-TH2 development. Nat Immunol 2000; 1:199-205; PMID:10973276; https://doi.org/10.1038/79734
   PubMed Web of Science ®Google Scholar
• Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005; 5:296-306; PMID:15803149; https://doi.org/10.1038/nri1592
   PubMed Web of Science ®Google Scholar
• Cohn L, Delamarre L. Dendritic cell-targeted vaccines. Front Immunol 2014; 5:255; PMID:24910635; https://doi.org/10.3389/fimmu.2014.00255
   PubMed Web of Science ®Google Scholar
• Finn OJ. Cancer immunology. N Eng J Med 2008; 358:2704-15; PMID:18565863; https://doi.org/10.1056/NEJMra072739
   PubMed Web of Science ®Google Scholar
• Lim S, Koo JH, Choi JM. Use of cell-penetrating peptides in dendritic cell-based vaccination. Immune Netw 2016; 16:33-43; PMID:26937230; https://doi.org/10.4110/in.2016.16.1.33
   PubMed Web of Science ®Google Scholar
• Miconnet I, Coste I, Beermann F, Haeuw JF, Cerottini JC, Bonnefoy JY, Romero P, Renno T. Cancer vaccine design: a novel bacterial adjuvant for peptide-specific CTL induction. J Immunol 2001; 166:4612-9; https://doi.org/10.4049/jimmunol.166.7.4612
   PubMed Web of Science ®Google Scholar
• Perret R, Sierro SR, Botelho NK, Corgnac S, Donda A, Romero P. Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity. Cancer Res 2013; 73:6597-608; PMID:24048821; https://doi.org/10.1158/0008-5472.CAN-13-0875
   PubMed Web of Science ®Google Scholar
• Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010; 11:373-84; PMID:20404851; https://doi.org/10.1038/ni.1863
   PubMed Web of Science ®Google Scholar
• Gajewski TF, Schreiber H, Fu YX. Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol 2013; 14:1014-22; PMID:24048123; https://doi.org/10.1038/ni.2703
   PubMed Web of Science ®Google Scholar
• Zuckerman JN. The importance of injecting vaccines into muscle. Different patients need different needle sizes. BMJ 2000; 321:1237-8; PMID:11082069; https://doi.org/10.1136/bmj.321.7271.1237
   PubMed Web of Science ®Google Scholar
• Dresser DW. Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen. Immunology 1962; 5:378-88; PMID:13887798
   PubMed Web of Science ®Google Scholar
• Parkhurst MR, Fitzgerald EB, Southwood S, Sette A, Rosenberg SA, Kawakami Y. Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2). Cancer Res 1998; 58:4895-901; PMID:9809996
   PubMed Web of Science ®Google Scholar
• Toda M, Martuza RL, Kojima H, Rabkin SD. In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity. J Immunol 1998; 160:4457-64; PMID:9574551
   PubMed Web of Science ®Google Scholar
• Jin JO, Zhang W, Du JY, Yu Q. BDCA1-positive dendritic cells (DCs) represent a unique human myeloid DC subset that induces innate and adaptive immune responses to Staphylococcus aureus infection. Infect Immunity 2014; 82:4466-76; PMID:25114114; https://doi.org/10.1128/IAI.01851-14
   PubMed Web of Science ®Google Scholar
• Naik SH, Proietto AI, Wilson NS, Dakic A, Schnorrer P, Fuchsberger M, Lahoud MH, O'Keeffe M, Shao QX, Chen WF et al. Cutting edge: generation of splenic CD8+ and CD8− dendritic cell equivalents in FMS-like tyrosine kinase 3 ligand bone marrow cultures. J Immunol 2005; 174:6592-7; PMID:15905497; https://doi.org/10.4049/jimmunol.174.11.6592
   PubMed Web of Science ®Google Scholar
• Pooley JL, Heath WR, Shortman K. Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8− dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells. J Immunol 2001; 166:5327-30; PMID:11313367; https://doi.org/10.4049/jimmunol.166.9.5327
   PubMed Web of Science ®Google Scholar
• Schnorrer P, Behrens GM, Wilson NS, Pooley JL, Smith CM, El-Sukkari D, Davey G, Kupresanin F, Li M, Maraskovsky E et al. The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture. Proc Natl Acad Sci USA 2006; 103:10729-34; PMID:16807294; https://doi.org/10.1073/pnas.0601956103
   PubMed Web of Science ®Google Scholar
• Salio M, Shepherd D, Dunbar PR, Palmowski M, Murphy K, Wu L, Cerundolo V. Mature dendritic cells prime functionally superior melan-A-specific CD8+ lymphocytes as compared with nonprofessional APC. J Immunol 2001; 167:1188-97; PMID:11466333; https://doi.org/10.4049/jimmunol.167.3.1188
   PubMed Web of Science ®Google Scholar
• Grodeland G, Fossum E, Bogen B. Polarizing T and B cell responses by APC-targeted subunit vaccines. Front Immunol 2015; 6:367; PMID:26257735; https://doi.org/10.3389/fimmu.2015.00367
   PubMed Web of Science ®Google Scholar
• Kaufman HL, Disis ML. Immune system versus tumor: shifting the balance in favor of DCs and effective immunity. J Clin Invest 2004; 113:664-7; PMID:14991063; https://doi.org/10.1172/JCI21148
   PubMed Web of Science ®Google Scholar
• Ma Y, Shurin GV, Gutkin DW, Shurin MR. Tumor associated regulatory dendritic cells. Semin Cancer Biol 2012; 22:298-306; https://doi.org/10.1016/j.semcancer.2012.02.010
   PubMed Web of Science ®Google Scholar
• Coffman RL, Sher A, Seder RA. Vaccine adjuvants: putting innate immunity to work. Immunity 2010; 33:492-503; PMID:21029960; https://doi.org/10.1016/j.immuni.2010.10.002
   PubMed Web of Science ®Google Scholar
• Zhang W, Okimura T, Xu L, Zhang L, Oda T, Kwak M, Yu Q, Jin JO. Ascophyllan functions as an adjuvant to promote anti-cancer effect by dendritic cell activation. Oncotarget 2016; 7:19284-98; PMID:27008707; https://doi.org/10.18632/oncotarget.8200
   PubMed Web of Science ®Google Scholar
• Zhang W, Yu X, Kwak M, Xu L, Zhang L, Yu Q, Jin JO. Maturation of dendritic cells by pullulan promotes anti-cancer effect. Oncotarget 2016; 7:44644-59; PMID:27341129; https://doi.org/10.18632/oncotarget.10183
   PubMed Web of Science ®Google Scholar
• Jin JO, Park HY, Xu Q, Park JI, Zvyagintseva T, Stonik VA, Kwak JY. Ligand of scavenger receptor class A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor-alpha. Blood 2009; 113:5839-47; PMID:19351958; https://doi.org/10.1182/blood-2008-10-184796
   PubMed Web of Science ®Google Scholar
• Brown GD, Taylor PR, Reid DM, Willment JA, Williams DL, Martinez-Pomares L, Wong SY, Gordon S. Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med 2002; 196:407-12; PMID:12163569; https://doi.org/10.1084/jem.20020470
   PubMed Web of Science ®Google Scholar
• Gersuk GM, Underhill DM, Zhu L, Marr KA. Dectin-1 and TLRs permit macrophages to distinguish between different Aspergillus fumigatus cellular states. J Immunol 2006; 176:3717-24; PMID:16517740; https://doi.org/10.4049/jimmunol.176.6.3717
   PubMed Web of Science ®Google Scholar
• Tan W, Yu KQ, Liu YY, Ouyang MZ, Yan MH, Luo R, Zhao XS. Anti-fatigue activity of polysaccharides extract from Radix Rehmanniae Preparata. Int J Biol Macromol 2012; 50:59-62; PMID:21983027; https://doi.org/10.1016/j.ijbiomac.2011.09.019
   PubMed Web of Science ®Google Scholar
• Tomoda M, Miyamoto H, Shimizu N. Structural features and anti-complementary activity of rehmannan SA, a polysaccharide from the root of Rehmannia glutinosa. Chem Pharma Bull 1994; 42:1666-8; PMID:7954919; https://doi.org/10.1248/cpb.42.625 10.1248/cpb.42.1666
   PubMed Web of Science ®Google Scholar
• Kuznetsova TA, Besednova NN, Somova LM, Plekhova NG. Fucoidan extracted from Fucus evanescens prevents endotoxin-induced damage in a mouse model of endotoxemia. Mar Drugs 2014; 12:886-98; PMID:24492521; https://doi.org/10.3390/md12020886
   PubMed Web of Science ®Google Scholar
• Zhang W, Oda T, Yu Q, Jin J-O. Fucoidan from Macrocystis pyrifera has powerful immune-modulatory effects compared to three other fucoidans. Mar Drugs 2015; 13:1084-104; PMID:25706632; https://doi.org/10.3390/md13031084
   PubMed Web of Science ®Google Scholar
• Inagawa H, Kohchi C, Soma G. Oral administration of lipopolysaccharides for the prevention of various diseases: benefit and usefulness. Anticancer Res 2011; 31:2431-6; PMID:21873155
   PubMed Web of Science ®Google Scholar
• Murakami M, Tsubata T, Shinkura R, Nisitani S, Okamoto M, Yoshioka H, Usui T, Miyawaki S, Honjo T. Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse. J Exp Med 1994; 180:111-21; PMID:8006578; https://doi.org/10.1084/jem.180.1.111
   PubMed Web of Science ®Google Scholar
• Oketani K, Inoue T, Murakami M. Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide. Eur J Pharmacol 2001; 427:159-66; PMID:11557269; https://doi.org/10.1016/S0014-2999(01)01234-1
   PubMed Web of Science ®Google Scholar
• Zhang W, Cho SY, Xiang G, Min KJ, Yu Q, Jin JO. Ginseng berry extract promotes maturation of mouse dendritic cells. PloS One 2015; 10:e0130926; PMID:26090808; https://doi.org/10.1371/journal.pone.0130926
   PubMed Web of Science ®Google Scholar
• Jin JO, Han X, Yu Q. Interleukin-6 induces the generation of IL-10-producing Tr1 cells and suppresses autoimmune tissue inflammation. J Auto Immunity 2013; 40:28-44; PMID:22921334; https://doi.org/10.1016/j.jaut.2012.07.009
   PubMed Web of Science ®Google Scholar
• Hermans IF, Silk JD, Yang J, Palmowski MJ, Gileadi U, McCarthy C, Salio M, Ronchese F, Cerundolo V. The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo. J Immunol Methods 2004; 285:25-40; PMID:14871532; https://doi.org/10.1016/j.jim.2003.10.017
   PubMed Web of Science ®Google Scholar