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OncoImmunology Volume 9, 2020 - Issue 1
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Review

Characterization of the human tumor microbiome reveals tumor-type specific intra-cellular bacteria

Ilana Livyatana Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel;b Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, IsraelView further author information
,
Deborah Nejmana Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, IsraelView further author information
,
Noam Shentalc Department of Mathematics and Computer Science, The Open University of Israel, Ra’anana, IsraelView further author information
&
Ravid Straussmana Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, IsraelCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9476-329XView further author information
ORCID Icon
Article: 1800957 | Received 20 Jul 2020, Accepted 21 Jul 2020, Published online: 29 Jul 2020

References

  • Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian ZR, Du J, Davis A, Mongare MM, Gould J, Frederick DT, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature. 2012;487(7408):500–3. doi:10.1038/nature11183.
  • Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, et al. Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science. 2017;357(6356):1156–1160. doi:10.1126/science.aah5043.
  • Goodman B, Gardner H. The microbiome and cancer. J Pathol. 2018;244:667–676.
  • Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, et al. The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science. 2020;368(6494):973–980. doi:10.1126/science.aay9189.
  • Poore GD, Kopylova E, Zhu Q, Carpenter C, Fraraccio S, Wandro S, Kosciolek T, Janssen S, Metcalf J, Song SJ, et al. Microbiome analyses of blood and tissues suggest cancer diagnostic approach. Nature. 2020;579(7800):567–574. doi:10.1038/s41586-020-2095-1.
  • Rodriguez RM, Hernandez BY, Menor M, Deng Y, Khadka VS. The landscape of bacterial presence in tumor and adjacent normal tissue across 9 major cancer types using TCGA exome sequencing. Comput Struct Biotechnol J. 2020;18:631–641. doi:10.1016/j.csbj.2020.03.003.
  • Douglas GM, Maffei VJ, Zaneveld JR, Yurgel SN, Brown JR, Taylor CM, Huttenhower C, Langille MGI. PICRUSt2 for prediction of metagenome functions. Nat Biotechnol. 2020;38(6):685–688. doi:10.1038/s41587-020-0548-6.
  • Riquelme E, Zhang Y, L Z, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, et al. Tumor microbiome diversity and composition influence pancreatic cancer outcomes. Cell. 2019;178(4):795–806.e12. doi:10.1016/j.cell.2019.07.008.

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