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OncoImmunology Volume 10, 2021 - Issue 1
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Editorial

Ferroptosis becomes immunogenic: implications for anticancer treatments

Daolin Tanga Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USACorrespondence[email protected]
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,
Oliver Keppb Equipe Labellisée Par la Ligue Contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France;c Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus; 94800 Villejuif, FranceORCID Iconhttps://orcid.org/0000-0002-6081-9558View further author information
ORCID Icon &
Guido Kroemerb Equipe Labellisée Par la Ligue Contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France;c Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus; 94800 Villejuif, France;d Pôle de Biologie, Hôpital Européen Georges Pompidou, Paris, France;e Suzhou Institute for Systems Biology, Chinese Academy of Sciences, Suzhou, China;f Department of Women’s and Children’s Health, Karolinska University Hospital, Stockholm, SwedenCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9334-4405View further author information
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Article: 1862949 | Received 07 Dec 2020, Accepted 08 Dec 2020, Published online: 29 Dec 2020

References

  • Yatim N, Cullen S, Albert ML. Dying cells actively regulate adaptive immune responses. Nat Rev Immunol. 2017;17:262–2. doi:10.1038/nri.2017.9.
  • Green DR, Ferguson T, Zitvogel L, Kroemer G. Immunogenic and tolerogenic cell death. Nat Rev Immunol. 2009;9:353–363. doi:10.1038/nri2545.
  • Kepp O, Marabelle A, Zitvogel L, Kroemer G. Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies. Nat Rev Clin Oncol. 2020;17(49–64):49–64. doi:10.1038/s41571-019-0272-7.
  • Galluzzi L, Vitale I, Warren S, Adjemian S, Agostinis P, Martinez AB, Chan TA, Coukos G, Demaria S, Deutsch E, et al. Consensus guidelines for the definition, detection and interpretation of immunogenic cell death. J Immunother Cancer. 2020;8:e000337. doi:10.1136/jitc-2019-000337.
  • Tang D, Chen X, Kang R, Kroemer G. Ferroptosis: molecular mechanisms and health implications. Cell Res. 2020. doi:10.1038/s41422-020-00441–1
  • Tang D, Kroemer G. Ferroptosis. Curr Biol. 2020;30:R1292–R1297. doi:10.1016/j.cub.2020.09.068.
  • Chen X, Li J, Kang R, Klionsky DJ, Tang D. Ferroptosis: machinery and regulation. Autophagy. 2020:1–28. doi:10.1080/15548627.2020.1810918.
  • Dixon SJ, Lemberg K, Lamprecht M, Skouta R, Zaitsev E, Gleason C, Patel D, Bauer A, Cantley A, Yang W, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(1060–1072):1060–1072. doi:10.1016/j.cell.2012.03.042.
  • Efimova I, Catanzaro E, Van der Meeren L, Turubanova VD, Hammad H, Mishchenko TA, Vedunova MV, Fimognari C, Bachert C, Coppieters F, et al. Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity. J Immunother Cancer. 2020;8:e001369. doi:10.1136/jitc-2020-001369.
  • Wen Q, Liu J, Kang R, Zhou B, Tang D. The release and activity of HMGB1 in ferroptosis. Biochem Biophys Res Commun. 2019;510:278–283. doi:10.1016/j.bbrc.2019.01.090.

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