15,877
Views
162
CrossRef citations to date
0
Altmetric
Review

Influenza vaccination in healthcare workers: A comprehensive critical appraisal of the literature

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 772-789 | Received 25 Apr 2017, Accepted 26 Jun 2017, Published online: 20 Oct 2017

References

  • Gasparini R, Amicizia D, Lai PL, Bragazzi NL, Panatto D. Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part I: Influenza life-cycle and currently available drugs. J Prev Med Hyg 2014; 55(3):69-85
  • Gasparini R, Amicizia D, Lai PL, Bragazzi NL, Panatto D. Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus. J Prev Med Hyg 2014; 55(4):109-29
  • Barberis I, Myles P, Ault SK, Bragazzi NL, Martini M. History and evolution of influenza control through vaccination: from the first monovalent vaccine to universal vaccines. J Prev Med Hyg 2016; 57(3):E115-E120
  • World Health Organization (WHO). Influenza (seasonal). Fact sheet November 2006. Available at http://www.who.int/mediacentre/factsheets/fs211/en/
  • Lee N, Ison MG. Diagnosis, management and outcomes of adults hospitalized with influenza. Antivir Ther 2012; 17(1 Pt B):143-57; PMID:22311561; https://doi.org/10.3851/IMP2059
  • Durando P, Iudici R, Alicino C, Alberti M, de Florentis D, Ansaldi F, Icardi G. Adjuvants and alternative routes of administration towards the development of the ideal influenza vaccine. Hum Vaccin 2011; 7 Suppl:29-40; https://doi.org/10.4161/hv.7.0.14560
  • Ansaldi F, de Florentiis D, Durando P, Icardi G. Fluzone(®) Intradermal vaccine: a promising new chance to increase the acceptability of influenza vaccination in adults. Expert Rev Vaccines 2012; 11(1):17-25; https://doi.org/10.1586/erv.11.154
  • Bragazzi NL, Orsi A, Ansaldi F, Gasparini R, Icardi G. Fluzone® intra-dermal (Intanza®/Istivac® Intra-dermal): An updated overview. Hum Vaccin Immunother 2016; 12(10):2616-2627; https://doi.org/10.1080/21645515.2016.1187343
  • Orsi A, Ansaldi F, de Florentiis D, Ceravolo A, Parodi V, Canepa P, Coppelli M, Icardi G, Durando P. Cross-protection against drifted influenza viruses: options offered by adjuvanted and intradermal vaccines. Hum Vaccin Immunother 2013; 9(3):582-90; PMID:23295230; https://doi.org/10.4161/hv.23239
  • Durando P, Fenoglio D, Boschini A, Ansaldi F, Icardi G, Sticchi L, Renzoni A, Fabbri P, Ferrera A, Parodi A, Bruzzone B, Gabutti G, Podda A, Del Giudice G, Fragapane E, Indiveri F, Crovari P, Gasparini R. Safety and immunogenicity of two influenza virus subunit vaccines, with or without MF59 adjuvant, administered to human immunodeficiency virus type 1-seropositive and -seronegative adults. Clin Vaccine Immunol 2008; 15(2):253-9; https://doi.org/10.1128/CVI.00316-07
  • Ansaldi F, Durando P, Icardi G. Intradermal influenza vaccine and new devices: a promising chance for vaccine improvement. Expert Opin Biol Ther 2011; 11(3):415-27; PMID:21299438; https://doi.org/10.1517/14712598.2011.557658
  • Brien S, Kwong JC, Buckeridge DL. The determinants of 2009 pandemic A/H1N1 influenza vaccination: a systematic review. Vaccine 2012; 30(7):1255-64; https://doi.org/10.1016/j.vaccine.2011.12.089
  • Collange F, Verger P, Launay O, Pulcini C. Knowledge, attitudes, beliefs and behaviors of general practitioners/family physicians toward their own vaccination: A systematic review. Hum Vaccin Immunother 2016; 12(5):1282-92; https://doi.org/10.1080/21645515.2015.1138024
  • Hollmeyer HG, Hayden F, Poland G, Buchholz U. Influenza vaccination of health care workers in hospitals–a review of studies on attitudes and predictors. Vaccine 2009; 27(30):3935-44 [accessed June 7 2017]; https://doi.org/10.1016/j.vaccine.2009.03.056
  • Hollmeyer H, Hayden F, Mounts A, Buchholz U. Review: interventions to increase influenza vaccination among healthcare workers in hospitals. Influenza Other Respir Viruses 2013; 7:604-21; PMID:22984794; https://doi.org/10.1111/irv.12002
  • Thomas RE, Jefferson T, Demicheli V, Rivetti D. Influenza vaccination for healthcare workers who work with the elderly. Cochrane Database Syst Rev 2006 Jul 19;(3):CD005187
  • Thomas RE, Jefferson T, Lasserson TJ. Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions. Cochrane Database Syst Rev 2016 Jun 2;(6):CD005187
  • Thomas RE, Jefferson TO, Demicheli V, Rivetti D. Influenza vaccination for health-care workers who work with elderly people in institutions: a systematic review. Lancet Infect Dis 2006; 6(5):273-9; https://doi.org/10.1016/S1473-3099(06)70462-5
  • Thomas RE, Jefferson T, Lasserson TJ. Influenza vaccination for healthcare workers who work with the elderly: systematic review. Vaccine 2010; 29(2):344-56
  • Thomas RE, Jefferson T, Lasserson TJ. Influenza vaccination for healthcare workers who work with the elderly. Cochrane Database Syst Rev 2010 Feb 17;(2):CD005187
  • Thomas RE, Jefferson T, Lasserson TJ. Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions. Cochrane Database Syst Rev 2013 Jul 22;(7):CD005187
  • Lietz J, Westermann C, Nienhaus A, Schablon A. The Occupational Risk of Influenza A (H1N1) Infection among Healthcare Personnel during the 2009 Pandemic: A Systematic Review and Meta-Analysis of Observational Studies. PLoS One 2016; 11(8):e0162061
  • Gambhir RS, Pannu PR, Nanda T, Arora G, Kaur A. Knowledge and Awareness Regarding Swine-Influenza A (H1N1) Virus Infection among Dental Professionals in India - A Systematic Review. J Clin Diagn Res 2016; 10(9):ZE10-ZE13
  • Ng AN, Lai CK. Effectiveness of seasonal influenza vaccination in healthcare workers: a systematic review. J Hosp Infect 2011; 79(4):279-86
  • Koh Y, Hegney DG, Drury V. Comprehensive systematic review of healthcare workers' perceptions of risk and use of coping strategies towards emerging respiratory infectious diseases. Int J Evid Based Healthc 2011; 9(4):403-19
  • Yiwen K, Hegney D, Drury V. A comprehensive systematic review of healthcare workers' perceptions of risk from exposure to emerging acute respiratory infectious diseases and the perceived effectiveness of strategies used to facilitate healthy coping in acute hospital and community healthcare settings. JBI Libr Syst Rev 2010; 8(23):917-971; PMID:27819952
  • Bish A, Yardley L, Nicoll A, Michie S. Factors associated with uptake of vaccination against pandemic influenza: a systematic review. Vaccine 2011; 29(38):6472-84
  • La Torre G, Mannocci A, Ursillo P, Bontempi C, Firenze A, Panico MG, Sferrazza A, Ronga C, D'Anna A, Amodio E, Romano N, Boccia A. Prevalence of influenza vaccination among nurses and ancillary workers in Italy: systematic review and meta analysis. Hum Vaccin 2011; 7(7):728-33; https://doi.org/10.4161/hv.7.7.15413
  • Maggiore UL, Scala C, Toletone A, Debarbieri N, Perria M, D'Amico B, Montecucco A, Martini M, Dini G, Durando P. Susceptibility to vaccine-preventable diseases and vaccination adherence among healthcare workers in Italy: A cross-sectional survey at a regional acute-care university hospital and a systematic review. Hum Vaccin Immunother 2017; 13(2):470-476; https://doi.org/10.1080/21645515.2017.1264746
  • Prematunge C, Corace K, McCarthy A, Nair RC, Pugsley R, Garber G. Factors influencing pandemic influenza vaccination of healthcare workers–a systematic review. Vaccine 2012 Jul 6; 30(32):4733-43; https://doi.org/10.1016/j.vaccine.2012.05.018
  • Nowak GJ, Sheedy K, Bursey K, Smith TM, Basket M. Promoting influenza vaccination: insights from a qualitative meta-analysis of 14 years of influenza-related communications research by U.S. Centers for Disease Control and Prevention (CDC). Vaccine 2015; 33(24):2741-56; https://doi.org/10.1016/j.vaccine.2015.04.064
  • Riphagen-Dalhuisen J, Gefenaite G, Hak E. Predictors of seasonal influenza vaccination among healthcare workers in hospitals: a descriptive meta-analysis. Occup Environ Med 2012; 69(4):230-5; https://doi.org/10.1136/oemed-2011-100134
  • Schmid P, Rauber D, Betsch C, Lidolt G, Denker ML. Barriers of Influenza Vaccination Intention and Behavior - A Systematic Review of Influenza Vaccine Hesitancy, 2005 - 2016. PLoS One 2017; 12(1):e0170550; https://doi.org/10.1371/journal.pone.0170550
  • Vasilevska M, Ku J, Fisman DN. Factors associated with healthcare worker acceptance of vaccination: a systematic review and meta-analysis. Infect Control Hosp Epidemiol 2014; 35(6):699-708; https://doi.org/10.1086/676427
  • Kliner M, Keenan A, Sinclair D, Ghebrehewet S, Garner P. Influenza vaccination for healthcare workers in the UK: appraisal of systematic reviews and policy options. BMJ Open 2016; 6(9):e012149; https://doi.org/10.1136/bmjopen-2016-012149
  • Kuster SP, Shah PS, Coleman BL, Lam PP, Tong A, Wormsbecker A, McGeer A. Incidence of influenza in healthy adults and healthcare workers: a systematic review and meta-analysis. PLoS One 2011; 6(10):e26239; PMID:22028840; https://doi.org/10.1371/journal.pone.0026239
  • Michiels B, Govaerts F, Remmen R, Vermeire E, Coenen S. A systematic review of the evidence on the effectiveness and risks of inactivated influenza vaccines in different target groups. Vaccine 2011; 29(49):9159-70; https://doi.org/10.1016/j.vaccine.2011.08.008
  • Restivo V, Costantino C, Bono S, Maniglia M, Marchese V, Ventura G, Casuccio A, Tramuto F, Vitale F. Influenza vaccine effectiveness among high-risk groups: a systematic literature review and meta-analysis of case-control and cohort studies. Hum Vaccin Immunother 2017; in press. https://doi.org/10.1080/21645515.2017.1321722
  • Ahmed F, Lindley MC, Allred N, Weinbaum CM, Grohskopf L. Effect of influenza vaccination of healthcare personnel on morbidity and mortality among patients: systematic review and grading of evidence. Clin Infect Dis 2014; 58(1):50-7; https://doi.org/10.1093/cid/cit580
  • De Serres G, Skowronski DM, Ward BJ, Gardam M, Lemieux C, Yassi A, Patrick DM, Krajden M, Loeb M, Collignon P, Carrat F. Influenza Vaccination of Healthcare Workers: Critical Analysis of the Evidence for Patient Benefit Underpinning Policies of Enforcement. PLoS One 2017; 12(1):e0163586; https://doi.org/10.1371/journal.pone.0163586
  • Dolan GP, Harris RC, Clarkson M, Sokal R, Morgan G, Mukaigawara M, Horiuchi H, Hale R, Stormont L, Béchard-Evans L, Chao YS, Eremin S, Martins S, Tam J, Peñalver J, Zanuzadana A, Nguyen-Van-Tam JS. Vaccination of healthcare workers to protect patients at increased risk of acute respiratory disease: summary of a systematic review. Influenza Other Respir Viruses 2013; 7 Suppl 2:93-6; https://doi.org/10.1111/irv.12087
  • Corace KM, Srigley JA, Hargadon DP, Yu D, MacDonald TK, Fabrigar LR, Garber GE. Using behavior change frameworks to improve healthcare worker influenza vaccination rates: A systematic review. Vaccine 2016; 34(28):3235-42; https://doi.org/10.1016/j.vaccine.2016.04.071
  • Lam PP, Chambers LW, MacDougall DM, McCarthy AE. Seasonal influenza vaccination campaigns for health care personnel: systematic review. CMAJ 2010; 182(12):E542-8; https://doi.org/10.1503/cmaj.091304
  • Lytras T, Kopsachilis F, Mouratidou E, Papamichail D, Bonovas S. Interventions to increase seasonal influenza vaccine coverage in healthcare workers: A systematic review and meta-regression analysis. Hum Vaccin Immunother 2016; 12(3):671-81; PMID:26619125; https://doi.org/10.1080/21645515.2015.1106656
  • Pitts SI, Maruthur NM, Millar KR, Perl TM, Segal J. A systematic review of mandatory influenza vaccination in healthcare personnel. Am J Prev Med 2014; 47(3):330-40; https://doi.org/10.1016/j.amepre.2014.05.035
  • Rashid H, Yin JK, Ward K, King C, Seale H, Booy R. Assessing Interventions To Improve Influenza Vaccine Uptake Among Health Care Workers. Health Aff (Millwood) 2016; 35(2):284-92; https://doi.org/10.1377/hlthaff.2015.1087
  • Schmidt S, Saulle R, Di Thiene D, Boccia A, La Torre G. Do the quality of the trials and the year of publication affect the efficacy of intervention to improve seasonal influenza vaccination among healthcare workers?: Results of a systematic review. Hum Vaccin Immunother 2013; 9(2):349-61; https://doi.org/10.4161/hv.22736
  • Siemieniuk R, Coleman B, Shafiz S, Al-Den A, Bornsten S, Kean R, McGeer A, Goodliffe L. Interventions to increase healthcare worker influenza vaccination: a meta-analysis. Poster ID1713 presented at the IDWeek2014. Advancing Science, Improving Care. October 8-12 2014, Philadelphia, PA, USA. Available at https://idsa.confex.com/idsa/2014/webprogram/Paper47456.html
  • Burls A, Jordan R, Barton P, Olowokure B, Wake B, Albon E, Hawker J. Vaccinating healthcare workers against influenza to protect the vulnerable–is it a good use of healthcare resources? A systematic review of the evidence and an economic evaluation. Vaccine 2006; 24(19):4212-21; https://doi.org/10.1016/j.vaccine.2005.12.043
  • Haviari S, Bénet T, Saadatian-Elahi M, André P, Loulergue P, Vanhems P. Vaccination of healthcare workers: A review. Hum Vaccin Immunother 2015; 11(11):2522-37; PMID:26291642; https://doi.org/10.1080/21645515.2015.1082014
  • To KW, Lai A, Lee KC, Koh D, Lee SS. Increasing the coverage of influenza vaccination in healthcare workers: review of challenges and solutions. J Hosp Infect 2016; 94(2):133-42; https://doi.org/10.1016/j.jhin.2016.07.003
  • Durando P, Alicino C, Dini G, Barberis I, Bagnasco AM, Iudici R, Zanini M, Martini M, Toletone A, Paganino C, Massa E, Orsi A, Sasso L. Determinants of adherence to seasonal influenza vaccination among healthcare workers from an Italian region: results from a cross-sectional study. BMJ Open 2016; 6(5):e010779; https://doi.org/10.1136/bmjopen-2015-010779
  • Llupià A, Puig J, Mena G, Bayas JM, Trilla A. The social network around influenza vaccination in health care workers: a cross-sectional study. Implement Sci 2016; 11(1):152; https://doi.org/10.1186/s13012-016-0522-3
  • Wilde JA, McMillan JA, Serwint J, Butta J, O'Riordan MA, Steinhoff MC. Effectiveness of influenza vaccine in health care professionals: a randomized trial. JAMA 1999; 281:908-13; PMID:10078487; https://doi.org/10.1001/jama.281.10.908
  • Mereckiene J, Cotter S, Nicoll A, Lopalco P, Noori T, Weber J, D'Ancona F, Levy-Bruhl D, Dematte L, Giambi C, Valentiner-Branth P, Stankiewicz I, Appelgren E, O Flanagan D, VENICE project gatekeepers group. Seasonal influenza immunisation in Europe. Overview of recommendations and vaccination coverage for three seasons: pre-pandemic (2008/09), pandemic (2009/10) and post-pandemic (2010/11). Euro Surveill 2014; 19(16):20780; https://doi.org/10.2807/1560-7917.ES2014.19.16.20780
  • Böhmer MM, Walter D, Falkenhorst G, Müters S, Krause G, Wichmann O. Barriers to pandemic influenza vaccination and uptake of seasonal influenza vaccine in the post-pandemic season in Germany. BMC Public Health 2012; 12:938; PMID:23113995; https://doi.org/10.1186/1471-2458-12-938
  • Alicino C, Iudici R, Barberis I, Paganino C, Cacciani R, Zacconi M, Battistini A, Bellina D, Di Bella AM, Talamini A, Sticchi L, Morando A, Ansaldi F, Durando P. Influenza vaccination among healthcare workers in Italy. Hum Vaccin Immunother 2015; 11(1):95-100; PMID:25483521; https://doi.org/10.4161/hv.34362
  • Poland GA. The 2009-2010 influenza pandemic: effects on pandemic and seasonal vaccine uptake and lessons learned for seasonal vaccination campaigns. Vaccine 2010; 28(Suppl 4):D3-13; PMID:20713258
  • Hakim H, Gaur AH, McCullers JA. Motivating factors for high rates of influenza vaccination among healthcare workers. Vaccine 2011; 29:5963-9; PMID:21699950; https://doi.org/10.1016/j.vaccine.2011.06.041
  • Wynia MK. Mandating Vaccination: What counts as a “Mandate” in Public Health and When should they be used? Am J Bioethics 2007; 7(12):2-6; https://doi.org/10.1080/15265160701795809
  • Wicker S, Marckmann G. Vaccination of health care workers against influenza: Is it time to think about a mandatory policy in Europe? Vaccine 2014; 32(38):4844-8
  • Septimus EJ, Perlin JB, Cormier SB, Moody JA, Hickok JD. A multifaceted mandatory patient safety program and seasonal influenza vaccination of health care workers in community hospitals. JAMA 2011; 305:999-1000; PMID:21386077; https://doi.org/10.1001/jama.2011.244
  • Hulo S, Nuvoli A, Sobaszek A, Salembier-Trichard A. Knowledge and attitudes towards influenza vaccination of health care workers in emergency services. Vaccine 2017; 35(2):205-207; https://doi.org/10.1016/j.vaccine.2016.11.086
  • Randall LH, Curran EA, Omer SB. Legal considerations surrounding mandatory influenza vaccination for healthcare workers in the United States. Vaccine 2013; 31(14):1771-6; https://doi.org/10.1016/j.vaccine.2013.02.002
  • Weber DJ, Orenstein W, Rutala WA. How to improve influenza vaccine coverage of healthcare personnel. Isr J Health Policy Res 2016; 5:61; https://doi.org/10.1186/s13584-016-0122-3
  • Manzoli L, Sotgiu G, Magnavita N, Durando P. National Working Group on Occupational Hygiene of the Italian Society of Hygiene, Preventive Medicine and Public Health (SItI); National Working Group on Occupational Hygiene of the Italian Society of Hygiene Preventive Medicine and Public Health SItI. Evidence-based approach for continuous improvement of occupational health. Epidemiol Prev 2015; 39(4 Suppl 1):81-5
  • Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Info Libr J 2009; 26(2):91-108; https://doi.org/10.1111/j.1471-1842.2009.00848.x
  • Aromataris E, Fernandez R, Godfrey CM, Holly C, Khalil H, Tungpunkom P. Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach. Int J Evid Based Healthc 2015; 13(3):132-40; https://doi.org/10.1097/XEB.0000000000000055
  • Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement. Open Med 2009; 3(3):e123-30; PMID:21603045
  • Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 2009; 6(7):e1000100; https://doi.org/10.1371/journal.pmed.1000100
  • Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 2015; 4:1; https://doi.org/10.1186/2046-4053-4-1
  • Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ 2015; 349:g7647; https://doi.org/10.1136/bmj.g7647
  • Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, Porter AC, Tugwell P, Moher D, Bouter LM. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol 2007; 7:10; https://doi.org/10.1186/1471-2288-7-10
  • Shea BJ, Bouter LM, Peterson J, Boers M, Andersson N, Ortiz Z, Ramsay T, Bai A, Shukla VK, Grimshaw JM. External validation of a measurement tool to assess systematic reviews (AMSTAR). PLoS One 2007; 2(12):e1350; https://doi.org/10.1371/journal.pone.0001350