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Research Paper

Type III hypersensitivity reactions to a B cell epitope antigen are abrogated using a depot forming vaccine platform

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Pages 59-66 | Received 05 Jun 2017, Accepted 31 Aug 2017, Published online: 30 Oct 2017

References

  • Koff WC, Burton DR, Johnson PR, Walker BD, King CR, Nabel GJ, Ahmed R, Bhan MK, Plotkin SA. Accelerating next-generation vaccine development for global disease prevention. Science. 2013;340:1232910. doi:10.1126/science.1232910. PMID:23723240
  • Lewis DJ, Lythgoe MP. Application of “systems vaccinology” to evaluate inflammation and reactogenicity of adjuvanted preventative vaccines. J Immunol Res. 2015;2015:909406. doi:10.1155/2015/909406. PMID:26380327
  • Moyle PM, Toth I. Modern subunit vaccines: development, components, and research opportunities. ChemMedChem. 2013;8:360-76. doi:10.1002/cmdc.201200487. PMID:23316023
  • Di Pasquale A, Preiss S, Tavares Da Silva F, Garcon N. Vaccine Adjuvants: from 1920 to 2015 and Beyond. Vaccines (Basel). 2015;3:320-43. doi:10.3390/vaccines3020320. PMID:26343190
  • Graham BS. Biological challenges and technological opportunities for respiratory syncytial virus vaccine development. Immunol Rev. 2011;239:149-66. doi:10.1111/j.1600-065X.2010.00972.x. PMID:21198670
  • Reed SG, Orr MT, Fox CB. Key roles of adjuvants in modern vaccines. Nat Med. 2013;19:1597-608. doi:10.1038/nm.3409. PMID:24309663
  • O'Hagan DT, Fox CB. New generation adjuvants–from empiricism to rational design. Vaccine. 2015;33(Suppl 2):B14-20. doi:10.1016/j.vaccine.2015.01.088. PMID:26022561
  • Wen Y, Shi Y. Alum: an old dog with new tricks. Emerg Microbes Infect. 2016;5:e25. doi:10.1038/emi.2016.40. PMID:27004761
  • Li H, Willingham SB, Ting JP, Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol. 2008;181:17-21. doi:10.4049/jimmunol.181.1.17. PMID:18566365
  • al-Shakhshir RH, Regnier FE, White JL, Hem SL. Contribution of electrostatic and hydrophobic interactions to the adsorption of proteins by aluminium-containing adjuvants. Vaccine. 1995;13:41-4. doi:10.1016/0264-410X(95)80009-3. PMID:7762276
  • Hutchison S, Benson RA, Gibson VB, Pollock AH, Garside P, Brewer JM. Antigen depot is not required for alum adjuvanticity. FASEB J. 2012;26:1272-9. doi:10.1096/fj.11-184556. PMID:22106367
  • Brewer KD, Lake K, Pelot N, Stanford MM, DeBay DR, Penwell A, Weir GM, Karkada M, Mansour M, Bowen CV. Clearance of depot vaccine SPIO-labeled antigen and substrate visualized using MRI. Vaccine. 2014;32:6956-62. doi:10.1016/j.vaccine.2014.10.058. PMID:25444822
  • Berinstein NL, Karkada M, Morse MA, Nemunaitis JJ, Chatta G, Kaufman H, Odunsi K, Nigam R, Sammatur L, MacDonald LD, et al. First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients. J Transl Med. 2012;10:156. doi:10.1186/1479-5876-10-156. PMID:22862954
  • Berinstein NL, Karkada M, Oza AM, Odunsi K, Villella JA, Nemunaitis JJ, Morse MA, Pejovic T, Bentley J, Buyse M, et al. Survivin-targeted immunotherapy drives robust polyfunctional T cell generation and differentiation in advanced ovarian cancer patients. Oncoimmunology. 2015;4:e1026529. doi:10.1080/2162402X.2015.1026529. PMID:26405584
  • MacDonald LD, Fuentes-Ortega A, Sammatur L, Mansour M. Efficacy of a single dose hepatitis B depot vaccine. Vaccine. 2010;28:7143-5. doi:10.1016/j.vaccine.2010.08.084. PMID:20832491
  • Committee IoMUVS. Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality. Washington,(DC: National Academies Press (US), 1994.
  • Siegrist CA. Mechanisms underlying adverse reactions to vaccines. J Comp Pathol. 2007;137(Suppl 1):S46-50. doi:10.1016/j.jcpa.2007.04.012. PMID:17559869
  • Schepens B, Sedeyn K, Vande Ginste L, De Baets S, Schotsaert M, Roose K, Houspie L, Van Ranst M, Gilbert B, van Rooijen N, et al. Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein. EMBO Mol Med. 2014;6:1436-54. doi:10.15252/emmm.201404005. PMID:25298406
  • Leach MW, Rottman JB, Hock MB, Finco D, Rojko JL, Beyer JC. Immunogenicity/hypersensitivity of biologics. Toxicol Pathol. 2014;42:293-300. doi:10.1177/0192623313510987. PMID:24240973
  • Khodoun MV, Strait R, Armstrong L, Yanase N, Finkelman FD. Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis. Proc Natl Acad Sci U S A. 2011;108:12413-8. doi:10.1073/pnas.1105695108. PMID:21746933
  • Kurella S, Manocha M, Sabhnani L, Thomas B, Rao DN. New age adjuvants and delivery systems for subunit vaccines. Indian J Clin Biochem. 2000;15:83-100. doi:10.1007/BF02867548. PMID:23105272
  • Reagan-Shaw S, Nihal M, Ahmad N. Dose translation from animal to human studies revisited. FASEB J. 2008;22:659-61. doi:10.1096/fj.07-9574LSF. PMID:17942826
  • Krishnan L, Twine S, Gerdts V, Barreto L, Richards JC. Canadian Adjuvant Initiative Workshop, March 26–27, 2013–Ottawa, Canada. Hum Vaccin Immunother. 2014;10:519-26. doi:10.4161/hv.26972. PMID:24192752
  • Brito LA, O'Hagan DT. Designing and building the next generation of improved vaccine adjuvants. J Control Release. 2014;190:563-79. doi:10.1016/j.jconrel.2014.06.027. PMID:24998942
  • Schijns VE, Lavelle EC. Trends in vaccine adjuvants. Expert Rev Vaccines. 2011;10:539-50. doi:10.1586/erv.11.21. PMID:21506650
  • Li W, Joshi MD, Singhania S, Ramsey KH, Murthy AK. Peptide Vaccine: Progress and Challenges. Vaccines (Basel). 2014;2:515-36. doi:10.3390/vaccines2030515. PMID:26344743
  • Brennan FR, Dougan G. Non-clinical safety evaluation of novel vaccines and adjuvants: new products, new strategies. Vaccine. 2005;23:3210-22. doi:10.1016/j.vaccine.2004.11.072. PMID:15837222
  • Forster R. Study designs for the nonclinical safety testing of new vaccine products. J Pharmacol Toxicol Methods. 2012;66:1-7. doi:10.1016/j.vascn.2012.04.003. PMID:22561062
  • Quakkelaar ED, Fransen MF, van Maren WW, Vaneman J, Loof NM, van Heiningen SH, Verbeek JS, Ossendorp F, Melief CJ. IgG-mediated anaphylaxis to a synthetic long peptide vaccine containing a B cell epitope can be avoided by slow-release formulation. J Immunol. 2014;192:5813-20. doi:10.4049/jimmunol.1302337. PMID:24813207
  • Karkada M, Weir GM, Quinton T, Sammatur L, MacDonald LD, Grant A, et al. A novel breast/ovarian cancer peptide vaccine platform that promotes specific type-1 but not Treg/Tr1-type responses. J Immunother. 2010;33:250-61. doi:10.1097/CJI.0b013e3181c1f1e9. PMID:20445345
  • Frey A, Di Canzio J, Zurakowski D. A statistically defined endpoint titer determination method for immunoassays. J Immunol Methods. 1998;221:35-41. doi:10.1016/S0022-1759(98)00170-7. PMID:9894896