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Rotavirus – Research Paper

Public health impact and cost-effectiveness of rotavirus vaccination in China: Comparison between private market provision and national immunization programs

ORCID Icon, , &
Article: 2090162 | Received 19 Feb 2022, Accepted 05 Jun 2022, Published online: 11 Jul 2022

References

  • World Health Organization. The immunological basis for immunization series: module 21: rotavirus vaccines. Geneva: World Health Organization; 2020.
  • World Health Organization. Rotavirus vaccines: WHO position paper—January 2013. Weekly Epidemiological Rec. 2013;88(5):1–13.
  • Troeger C, Khalil IA, Rao PC, Cao S, Blacker BF, Ahmed T, Armah G, Bines JE, Brewer TG, Colombara DV, et al. Rotavirus vaccination and the global burden of rotavirus diarrhea among children younger than 5 years. JAMA Pediatr. 2018;172(10):958. doi:10.1001/jamapediatrics.2018.1960.
  • World Health Organization. Rotavirus. [accessed 2022 Feb 10]. https://www.who.int/teams/health-product-policy-and-standards/standards-and-specifications/vaccines-quality/rotavirus.
  • Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass RI. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis. 2003;9(5):565–572. doi:10.3201/eid0905.020562.
  • Clark A, Black R, Tate J, Roose A, Kotloff K, Lam D, Blackwelder W, Parashar U, Lanata C, Kang G, et al. Estimating global, regional and national rotavirus deaths in children aged <5 years: current approaches, new analyses and proposed improvements. Plos One. 2017;12(9):e0183392. doi:10.1371/journal.pone.0183392.
  • Parashar UD, Cortese MM, Offit PA. 52 - Rotavirus Vaccines. In: Plotkin S, Orenstein W, Offit P, Edwards K, editors. Plotkin’s Vaccines. 7th ed. Philadelphia, PA:Elsevier; 2018. p. 950–969.e11.
  • Soares Weiser K, Bergman H, Henschke N, Pitan F, Cunliffe N. Vaccines for preventing rotavirus diarrhoea: vaccines in use. Cochrane Database Syst Rev. 2019;(10). doi:10.1002/14651858.CD008521.pub4.
  • World Health Organization. Rotavirus vaccines: WHO position paper—January 2021. Weekly Epidemiological Rec. 2019;96(28): 301-219.
  • International Vaccine Access Center (IVAC), Johns Hopkins Bloomberg School. VIEW-Hub. [accessed 2022 Feb 10]. www.view-hub.org.
  • Parashar UD, Johnson H, Steele AD, Tate JE. Health impact of rotavirus vaccination in developing countries: progress and way forward. Clin Infect Dis. 2016;62(Suppl 2):S91–5. doi:10.1093/cid/civ1015.
  • Aliabadi N, Antoni S, Mwenda JM, Weldegebriel G, Biey J, Cheikh D, Fahmy K, Teleb N, Ashmony HA, Ahmed H, et al. Global impact of rotavirus vaccine introduction on rotavirus hospitalisations among children under 5 years of age, 2008–16: findings from the global rotavirus surveillance network. Lancet Glob Health. 2019;7(7):e893–e903. doi:10.1016/S2214-109X(19)30207-4.
  • Karafillakis E, Hassounah S, Atchison C. Effectiveness and impact of rotavirus vaccines in Europe, 2006-2014. Vaccine. 2015;33(18):2097–2107. doi:10.1016/j.vaccine.2015.03.016.
  • Tate JE, Burton AH, Boschi-Pinto C, Parashar UD. Global, regional, and national estimates of rotavirus mortality in children <5 years of age, 2000-2013. Clin Infect Dis. 2016;62(Suppl 2):S96–S105. doi:10.1093/cid/civ1013.
  • Jin H, Wang B, Fang Z, Duan Z, Gao Q, Liu N, Zhang L, Qian Y, Gong S, Zhu Q, et al. Hospital-Based study of the economic burden associated with rotavirus diarrhea in eastern China. Vaccine. 2011;29(44):7801–7806. doi:10.1016/j.vaccine.2011.07.104.
  • Kawai K, O’-Brien MA, Goveia MG, Mast TC, El Khoury AC. Burden of rotavirus gastroenteritis and distribution of rotavirus strains in Asia: a systematic review. Vaccine. 2012;30(7):1244–1254. doi:10.1016/j.vaccine.2011.12.092.
  • Kirkwood CD, Steele AD. Rotavirus vaccines in China. JAMA Network Open. 2018;1(4):e181579. doi:10.1001/jamanetworkopen.2018.1579.
  • Yangtze River Delta Immunization Integration Working Group, Chinese Medical Association Infectious Diseases Branch Children′s Infection and Hepatology Group Expert consensus on the prevention, diagnosis and treatment of rotavirus gastroenteritis (RVGE) in children (2020). Chin J Prev Med. 2020;54(4):392-405. (in Chinese).
  • Zheng Y, Rodewald L, Yang J, Qin Y, Pang M, Feng L, Yu H. The landscape of vaccines in China: history, classification, supply, and price. BMC Infect Dis. 2018;18(1). doi:10.1186/s12879-018-3422-0.
  • Liu Y, Yue C, Li Y, Wang Y, Gao S, Wang Z, Xie X, Zhao H, Wang D, Liang X, et al. Analysis of vaccination situation of orial live attenuated rotavirus vaccine (LLR strain) among children in 6 provinces of China. Chin J Prev Med. 2018;52(3):282–286. (in Chinese). doi:10.4103/0366-6999.223851.
  • Aldemir-Kocabaş B, Karbuz A, Özdemir H, Tural-Kara T, Tapısız A, Belet N, Güriz H, Çiftçi E, İ̇nce E. Complications with rotavirus: a single center experiences. Turk J Pediatr. 2016;58(6):602–608. doi:10.24953/turkjped.2016.06.005.
  • Meloni A, Locci D, Frau G, Masia G, Nurchi AM, Coppola RC. Epidemiology and prevention of rotavirus infection: an underestimated issue? J Matern Fetal Neonatal Med. 2011;24(Suppl 2):48–51. doi:10.3109/14767058.2011.601920.
  • Sun S, Gao Y, Yin J, Zhuang G. A cost-effectiveness analysis on universal infant rotavirus vaccination strategy in China. Chin J Epidemiol. 2016;37(2):238–242. (in Chinese). doi:10.3760/cma.j.issn.0254-6450.2016.02.018.
  • Liu N, Yen C, Fang Z, Tate JE, Jiang B, Parashar UD, Zeng G, Duan Z-J. Projected health impact and cost-effectiveness of rotavirus vaccination among children <5 years of age in China. Vaccine. 2012;30(48):6940–6945. doi:10.1016/j.vaccine.2012.05.084.
  • Wang XY, Riewpaiboon A, von Seidlein L, Chen XB, Kilgore PE, Ma JC, Qi S-X, Zhang Z-Y, Hao Z-Y, Chen J-C, et al. Potential cost-effectiveness of a rotavirus immunization program in rural China. Clin Infect Dis. 2009;49(8):1202–1210. doi:10.1086/605632.
  • Cui S, Tobe RG, Mo X, Liu X, Xu L, Li S. Cost-Effectiveness analysis of rotavirus vaccination in China: projected possibility of scale-up from the current domestic option. BMC Infect Dis. 2016;16(1):677. doi:10.1186/s12879-016-2013-1.
  • Li R, Huang T, Li Y, Luo D, Tao J, Fu B, Si G, Nong Y, Mo Z-J, Liao X-Y, et al. Human rotavirus vaccine (RIX4414) efficacy in the first two years of life. Hum Vaccines Immunother. 2014;10(1):11–18. doi:10.4161/hv.26319.
  • Velázquez FR. Protective effects of natural rotavirus infection. Pediatr Infect Dis J. 2009;28(3):S54–S56. doi:10.1097/INF.0b013e3181967c03.
  • World Health Organization. WHO guide for standardization of economic evaluations of immunization programmes. 2nd ed. Geneva: World Health Organization; 2019.
  • The World Bank. Inflation, consumer prices (annual %) - China | Data. [accessed 2022 Feb 11]. https://www.vacmic.com/htm/20163/13_984.htm.
  • Global Burden of Disease Collaborative Network. Global burden of disease study 2019 (GBD 2019) results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME); 2020. [accessed 2022 Feb 10]. http://ghdx.healthdata.org/gbd-results-tool.
  • UN Inter-agency Group for Child Mortality Estimation. [accessed 2022 Feb 10]. https://childmortality.org/data/.
  • Liu Z, Liu X, He C, Miao L, Kang L, Li X, Zhu J, Li Q, Huang Y, Wang YP, et al. [Analysis of mortality and leading causes of death in Chinese children under 5-year-old between 2010 and 2016]. Chin J Prev Med. 2019;53(4):411–414. (in Chinese). doi:10.3760/cma.j.issn.0253-9624.2019.04.016.
  • Liu N, Xu Z, Li D, Zhang Q, Wang H, Duan Z. Update on the disease burden and circulating strains of rotavirus in China: a systematic review and meta-analysis. Vaccine. 2014;32(35):4369–4375. doi:10.1016/j.vaccine.2014.06.018.
  • Zhang J, Liu H, Jia L, Payne DC, Hall AJ, Xu Z, Gao Z, Chang Z, Jiang B, Parashar UD, et al. Active, population-based surveillance for rotavirus gastroenteritis in Chinese children: Beijing Municipality and Gansu Province, China. Pediatr Infect Dis J. 2015;34(1):40–46. doi:10.1097/INF.0000000000000505.
  • Wang J, Zhou H, Mo Z, Wang S, Hao Z, Li Y, Zhen S-S, Zhang C-J, Zhang X-J, Ma J-C, et al. Burden of viral gastroenteritis in children living in rural China: population-based surveillance. Int J Infect Dis. 2019;90:151–160. doi:10.1016/j.ijid.2019.10.029.
  • Lin Y, Wang J, Fu X, Wang X, Shen Z, Jiang W, Xu R, Shen G. Investigation on the burden of diarrhoeal disease among community population in Jiaxing city. Chin J Public Health Manage. 2013;29(2):158–160. (in Chinese).
  • Zhao S, Luo K, Hu S, Deng Z, Ouyang Y, Zhang X, Long Q, Yao Z, Gao L, Li J. Epidemiological characteristics of diarrhea and behaviors of seeking medical advice in rural residents in Hunan. China Trop Med. 2018;18(1):41–44. (in Chinese).
  • Yang Z Disease burden of acute gastroenteritis during autumn and winter among children under 5 years old in Henan Suixian [ Master Thesis]. Beijing, China: Chinese Center for Disease Control and Prevention; 2017. (in Chinese)
  • Yu J Research on Etiological spectrum and incidence estimation of diarrhoeal diseases [ Doctor Thesis]. Beijing, China: Chinese Center for Disease Control and Prevention; 2015. (in Chinese)
  • Brisson M, Senecal M, Drolet M, Mansi JA. Health-Related quality of life lost to rotavirus-associated gastroenteritis in children and their parents: a Canadian prospective study. Pediatr Infect Dis J. 2010;29(1):73–75. doi:10.1097/INF.0b013e3181b41506.
  • Martin A, Cottrell S, Standaert B. Estimating utility scores in young children with acute rotavirus gastroenteritis in the UK. J Med Econ. 2008;11(3):471–484. doi:10.3111/13696990802321047.
  • Marlow R, Finn A, Trotter C. Quality of life impacts from rotavirus gastroenteritis on children and their families in the UK. Vaccine. 2015;33(39):5212–5216. doi:10.1016/j.vaccine.2015.07.012.
  • Hoffmann T, Iturriza M, Faaborg-Andersen J, Kraaer C, Nielsen CP, Gray J, Hogh B. Prospective study of the burden of rotavirus gastroenteritis in Danish children and their families. Eur J Pediatr. 2011;170(12):1535–1539. doi:10.1007/s00431-011-1465-y.
  • Rochanathimoke O, Riewpaiboon A, Postma MJ, Thinyounyong W, Thavorncharoensap M. Health related quality of life impact from rotavirus diarrhea on children and their family caregivers in Thailand. Expert Rev Pharmacoecon Outcomes Res. 2018;18(2):215–222. doi:10.1080/14737167.2018.1386561.
  • Maneekarn N, Khamrin P. Rotavirus associated gastroenteritis in Thailand. VirusDisease. 2014;25(2):201–207. doi:10.1007/s13337-014-0201-4.
  • Zhang J, Duan Z, Payne DC, Yen C, Pan X, Chang Z, Liu N, Ye J, Ren X, Tate JE, et al. Rotavirus-Specific and overall diarrhea mortality in Chinese children younger than 5 years. Pediatr Infect Dis J. 2015;34(10):e233–e237. doi:10.1097/INF.0000000000000799.
  • Lanzhou Institute of Biological Products Co. LTD. Lanzhou Lamb rotavirus vaccine. [accessed 2022 Feb 10]. https://www.vacmic.com/htm/20163/13_984.htm/.
  • Lai X, Rong H, Ma X, Hou Z, Li S, Jing R, Zhang H, Peng Z, Feng L, Fang H, et al. Willingness to pay for seasonal influenza vaccination among children, chronic disease patients, and the elderly in China: a national cross-sectional survey. Vaccines. 2020;8(3):405. doi:10.3390/vaccines8030405.
  • Cao L, Wang HQ, Zheng JS, Yuan P, Cao LS, Zhang GM. National immunization coverage survey in China after integrated more vaccines into EPI since 2008. Chin J Vaccines Immunization. 2012;18(5):419–424+478. (in Chinese).
  • Mo Z, Mo Y, Li M, Tao J, Yang X, Kong J, Wei D, Fu B, Liao X, Chu J, et al. Efficacy and safety of a pentavalent live human-bovine reassortant rotavirus vaccine (RV5) in healthy Chinese infants: a randomized, double-blind, placebo-controlled trial. Vaccine. 2017;35(43):5897–5904. doi:10.1016/j.vaccine.2017.08.081.
  • Burnett E, Parashar UD, Tate JE. Real-World effectiveness of rotavirus vaccines, 2006–19: a literature review and meta-analysis. Lancet Global Health. 2020;8(9):e1195–e1202. doi:10.1016/S2214-109X(20)30262-X.
  • Pempa,, Luz A, Luangasanatip N, Kingkaew P, Adhikari D, Isaranuwatchai W, Choiphel D, Pecenka C, Debellut F. Economic evaluation of rotavirus vaccination in children of Bhutan. Vaccine. 2020;38(32):5049–5059. doi:10.1016/j.vaccine.2020.05.035.
  • Zhen S, Li Y, Wang S, Zhang X, Hao Z, Chen Y, Wang D, Zhang Y-H, Zhang Z-Y, Ma J-C, et al. Effectiveness of the live attenuated rotavirus vaccine produced by a domestic manufacturer in China studied using a population-based case–control design. Emerging Microbes Infections. 2015;4(1):1–6. doi:10.1038/emi.2015.64.
  • Li J, Zhang Y, Yang Y, Liang Z, Tian Y, Liu B, Gao Z, Jia L, Chen L, Wang Q, et al. Effectiveness of Lanzhou lamb rotavirus vaccine in preventing gastroenteritis among children younger than 5 years of age. Vaccine. 2019;37(27):3611–3616. doi:10.1016/j.vaccine.2019.03.069.
  • Fischer TK, Valentiner-Branth P, Steinsland H, Perch M, Santos G, Aaby P, Mølbak K, Sommerfelt H. Protective immunity after natural rotavirus infection: a community cohort study of newborn children in Guinea-Bissau, West Africa. J Infect Dis. 2002;186(5):593–597. doi:10.1086/342294.
  • Gladstone BP, Ramani S, Mukhopadhya I, Muliyil J, Sarkar R, Rehman AM, Jaffar S, Gomara MI, Gray JJ, Brown DWG, et al. Protective effect of natural rotavirus infection in an Indian Birth Cohort. N Engl J Med. 2011;365(4):337–346. doi:10.1056/NEJMoa1006261.
  • Zhang L, Li K, Du W, Li Y, Fan C, Yu W, Cao L, Cao L, Yin Z. Surveillance of adverse events following immunization in China, 2019. Chin J Vaccines Immunization. 2021;27(4):438–445. (in Chinese).
  • Chai C Study on epidemic characteristics and disease burden of diarrhea [ Master Thesis]. Zhejiang, China: Zhejiang University; 2010. (in Chinese)
  • National Bureau of Statistics of China. China statistics yearbook 2014. Beijing: China Statistics Press; 2014.
  • Ministry of health of China. China health statistical yearbook 2014. Beijing: Peking Union Medical College Press; 2014.
  • Zhang H, Garcia C, Yu W, Knoll MD, Lai X, Xu T, Jing R, Qin Y, Yin Z, Wahl B, et al. National and provincial impact and cost-effectiveness of Haemophilus influenzae type b conjugate vaccine in China: a modeling analysis. BMC Med. 2021;19(1). doi:10.1186/s12916-021-02049-7.
  • National Bureau of Statistics of China. Tabulation on the 2010 population census of the People’s Republic of China. [accessed 2022 Feb 11]. http://www.stats.gov.cn/tjsj/pcsj/rkpc/6rp/indexch.htm.
  • Zhuang J, Wagner AL, Laffoon M, Lu Y, Jiang Q. Procurement of category 2 vaccines in China. Vaccines (Basel). 2019;7(3):97. doi:10.3390/vaccines7030097.
  • Vaccines for Children Program (VFC) | Current CDC Vaccine Price List | CDC. [accessed 2022 Feb 11]. https://www.cdc.gov/vaccines/programs/vfc/awardees/vaccine-management/price-list/index.html.
  • Yu W, Lu M, Wang H, Rodewald L, Ji S, Ma C, Li Y, Zheng J, Song Y, Wang M, et al. Routine immunization services costs and financing in China, 2015. Vaccine. 2018;36(21):3041–3047. doi:10.1016/j.vaccine.2018.04.008.
  • Su S, Wong WC, Zou Z, Cheng DD, Ong JJ, Chan P, Ji F, Yuen M-F, Zhuang G, Seto W-K, et al. Cost-Effectiveness of universal screening for chronic hepatitis B virus infection in China: an economic evaluation. Lancet Global Health. 2022;10(2):e278–e287. doi:10.1016/S2214-109X(21)00517-9.
  • Pan XF, Griffiths UK, Pennington M, Yu H, Jit M. Systematic review of economic evaluations of vaccination programs in mainland China: are they sufficient to inform decision making? Vaccine. 2015;33(46):6164–6172. doi:10.1016/j.vaccine.2015.09.081.
  • Woods B, Revill P, Sculpher M, Claxton K. Country-level cost-effectiveness thresholds: initial estimates and the need for further research. Value Health. 2016;19(8):929–935. doi:10.1016/j.jval.2016.02.017.
  • Bertram MY, Lauer JA, De Joncheere K, Edejer T, Hutubessy R, Kieny M, Hill SR. Cost–effectiveness thresholds: pros and cons. Bull World Health Organ. 2016;94(12):925–930. doi:10.2471/BLT.15.164418.
  • Marseille E, Larson B, Kazi DS, Kahn JG, Rosen S. Thresholds for the cost–effectiveness of interventions: alternative approaches. Bull World Health Organ. 2015;93(2):118–124. doi:10.2471/BLT.14.138206.
  • Department Of Population And Employment Statistics, National Bureau Of Statistics. China population and employment statistics yearbook 2020. Beijing: China Statistics Press; 2020.
  • Wahl B, O’Brien KL, Greenbaum A, Majumder A, Liu L, Chu Y, Lukšić I, Nair H, McAllister DA, Campbell H, et al. Burden of streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000–15. Lancet Glob Health. 2018;6(7):e744–e757. doi:10.1016/S2214-109X(18)30247-X.
  • Geng Q, Lai S, Yu J, Zhang Z, Yang W, Li Z, Wu J, Yang W. Epidemiological characteristics of rotavirus caused diarrhea in children aged< 5 years in 26 provinces in China, 2011 to 2014. Dis Surveillance. 2016;31(6):463–470. (in Chinese).
  • Li J, Wang H, Li D, Zhang Q, Liu N. Infection status and circulating strains of rotaviruses in Chinese children younger than 5-years old from 2011 to 2018: systematic review and meta-analysis. Hum Vaccin Immunother. 2021;17(6):1811–1817. doi:10.1080/21645515.2020.1849519.
  • Shepard DS, Undurraga EA, Halasa YA, Stanaway JD. The global economic burden of dengue: a systematic analysis. Lancet Infect Dis. 2016;16(8):935–941. doi:10.1016/S1473-3099(16)00146-8.
  • Lai X, Wahl B, Yu W, Xu T, Zhang H, Garcia C, Qin Y, Guo Y, Yin Z, Knoll MD, et al. National, regional, and provincial disease burden attributed to streptococcus pneumoniae and Haemophilus influenzae type b in children in China: modelled estimates for 2010–17. Lancet Reg Health West Pac. 2022;22:100430. doi:10.1016/j.lanwpc.2022.100430.
  • Cui P Study on disease burden of rotavirus diarrhea and epidemiologic characteristic of intussusception among children in China [ Master Thesis]. Beijing, China: Chinese Center for Disease Control and Prevention; 2016. (in Chinese)
  • Fang Z, Zhang L, Tang J, Zhang Q, Hu H, Xie H, Zheng L. Study on rotavirus diarrhea among children in Lulong County, Hebei Province, China. Chin J Virol. 2005;21(1):21–26. (in Chinese).
  • Tang J, Fang Z, Hu H, Ye Q, Gao F, Liu C, Wang Y, Zhao X. Study on disease burden and character of rotavirus diarrhea among children in Lulong county of China. Chin J Child Health Care. 2007;15(2):179–180. (in Chinese).
  • Lou J, Xu X, Wu Y, Tao R, Tong M. Epidemiology and burden of rotavirus infection among children in Hangzhou, China. J Clin Virol. 2011;50(1):84–87. doi:10.1016/j.jcv.2010.10.003.
  • Zhang L Rotavirus Surveillance and Molecular Epidemiology among children with acute diarrhea in six regions of China [ Doctoral Thesis]. Beijing, China: Chinese Center for Disease Control and Prevention; 2005. (in Chinese)
  • Wu S, Wang B, Jin H, Wang N. Surveillance and estimates of disease burden on group a rotavirus gastroenteritis. J Southeast Univ (Med Sci Ed). 2003;22(2):80–83. (in Chinese).
  • Xiong L, Lin S, Li H. Study on the incidence and economic burden of rotavirus diarrhea in Longgang district of Shenzhen. Mod Prev Med. 2010;37(12):2332–2333. (in Chinese).
  • Li J, Cui P, Tao Y, Jin Y, Liu N. Economic burden of rotavirus diarrhea in children under 5 years old in Nanjing. Int J Virol . 2019;26(4):229–232. (in Chinese).
  • Liu H, Study on disease burden of rotavirus diarrhea among children under five years old in Beijing and Gansu [ Master Thesis]. Beijing, China: Chinese Center for Disease Control and Prevention; 2013. (in Chinese)
  • Jia L, Liu X, Li H, Liang Y, Gao Z, Wang Q. Study on the economic burden of rotavirus diarrhea among children under 5 years old in Beijing. Chin J Vaccines Immunization. 2015;21(5):543–546+551. (in Chinese).
  • Liu H, Liu X, Liu D, Zhang J, Meng L. Analysis on economic burden evaluation and epidemiology of rotavirus diarrhea among children under five years old. Chin Primary Health Care. 2014;28(6):90–92. (in Chinese).
  • Baral R, Nonvignon J, Debellut F, Agyemang SA, Clark A, Pecenka C. Cost of illness for childhood diarrhea in low- and middle-income countries: a systematic review of evidence and modelled estimates. BMC Public Health. 2020;20(1). doi:10.1186/s12889-020-08595-8.
  • Jampanil N, Kumthip K, Yodmeeklin A, Kanai Y, Okitsu S, Kobayashi T, Ukarapol N, Ushijima H, Maneekarn N, Khamrin P, et al. Epidemiology and genetic diversity of group a rotavirus in pediatric patients with acute gastroenteritis in Thailand, 2018–2019. Infect Genet Evol. 2021;95:104898. doi:10.1016/j.meegid.2021.104898.
  • Sumriddetchkajorn K, Shimazaki K, Ono T, Kusaba T, Sato K, Kobayashi N. Universal health coverage and primary care, Thailand. Bull World Health Organ. 2019;97(6):415–422. doi:10.2471/BLT.18.223693.
  • Yip W, Fu H, Chen AT, Zhai T, Jian W, Xu R, Pan J, Hu M, Zhou Z, Chen Q, et al. 10 years of health-care reform in China: progress and gaps in universal health coverage. Lancet. 2019;394(10204):1192–1204. doi:10.1016/S0140-6736(19)32136-1.
  • National Health Commission Of China. National immunization program schedule and instructions (2021). [accessed 2022 May 15]. cdcp.gd.gov.cn/attachment/0/416/416672/3437452.pdf.
  • Haider S, Chaikledkaew U, Thavorncharoensap M, Youngkong S, Islam MA, Thakkinstian A. Systematic review and meta-analysis of cost-effectiveness of rotavirus vaccine in low-income and lower-middle-income countries. Open Forum Infect Dis. 2019;6(4). doi:10.1093/ofid/ofz117.
  • Kotirum S, Vutipongsatorn N, Kongpakwattana K, Hutubessy R, Chaiyakunapruk N. Global economic evaluations of rotavirus vaccines: a systematic review. Vaccine. 2017;35(26):3364–3386. doi:10.1016/j.vaccine.2017.04.051.
  • Rochanathimoke O, Riewpaiboon A, Praditsitthikorn N, Tharmaphornpilas P, Jiamsiri S, Thavorncharoensap M, Postma MJ. Economic evaluation of rotavirus vaccination: an important step of the introduction to the national immunization program in Thailand. Expert Rev of Pharmacoecon Outcomes Res. 2021;21(4):811–819. doi:10.1080/14737167.2021.1932468.
  • Saokaew S, Prasitsuebsai W, Bibera GL, Kengkla K, Zhang X, Oh K, Lee C. Economic evaluation of human rotavirus vaccine in Thailand. Infect Dis Ther. 2019;8(3):397–415. doi:10.1007/s40121-019-0246-1.
  • Rotavirus vaccine (RV) price data | UNICEF Supply Division. [accessed 2022 Feb 11]. https://www.unicef.org/supply/documents/rotavirus-vaccine-rv-price-data.
  • Fu C, Dong Z, Shen J, Yang Z, Liao Y, Hu W, Pei S, Shaman J. Rotavirus gastroenteritis infection among children vaccinated and unvaccinated with rotavirus vaccine in Southern China. JAMA Network Open. 2018;1(4):e181382. doi:10.1001/jamanetworkopen.2018.1382.
  • Gavi, The Vaccine Alliance. Key concepts: economics of vaccine production. [accessed 2022 Feb 11]. https://www.who.int/immunization/programmes_systems/financing/analyses/en/briefcase_vacproduction.pdf
  • Mast TC, Wang FT, Su S, Seeger JD. Evidence of herd immunity and sustained impact of rotavirus vaccination on the reduction of rotavirus-related medical encounters among infants from 2006 through 2011 in the United States. Pediatr Infect Dis J. 2015;34(6):615–620. doi:10.1097/INF.0000000000000702.
  • Bennett A, Bar-Zeev N, Cunliffe NA. Measuring indirect effects of rotavirus vaccine in low income countries. Vaccine. 2016;34(37):4351–4353. doi:10.1016/j.vaccine.2016.07.001.
  • Kurosawa T, Watanabe H, Takahashi K. Cost-utility analysis of rotavirus vaccines including the latest evidence and data as of June 2020 in Japan. Pediatr Infect Dis J. 2021;40(2):162–168. doi:10.1097/INF.0000000000002938.
  • Nymark LS, Sharma T, Miller A, Enemark U, Griffiths UK. Inclusion of the value of herd immunity in economic evaluations of vaccines. A systematic review of methods used. Vaccine. 2017;35(49 Pt B):6828–6841. doi:10.1016/j.vaccine.2017.10.024.
  • Yu J, Lai S, Geng Q, Ye C, Zhang Z, Zheng Y, Wang L, Duan Z, Zhang J, Wu S, et al. Prevalence of rotavirus and rapid changes in circulating rotavirus strains among children with acute diarrhea in China, 2009–2015. J Infect. 2019;78(1):66–74. doi:10.1016/j.jinf.2018.07.004.
  • Wang L, Zhou S, Wang X, Lu Q, Shi L, Ren X, et al. Etiological, epidemiological, and clinical features of acute diarrhea in China. Nat Commun. 2021;12(1);2464.
  • Xia S, Du J, Su J, Liu Y, Huang L, Yu Q, Xie Z, Gao J, Xu B, Gao X, et al. Efficacy, immunogenicity and safety of a trivalent live human-lamb reassortant rotavirus vaccine (LLR3) in healthy Chinese infants: a randomized, double-blind, placebo-controlled trial. Vaccine. 2020;38(46):7393–7400. doi:10.1016/j.vaccine.2020.04.038.
  • The high-level seminar on evidence-based decision-making of national immunization Program was successfully held in Beijing. [accessed 2022 Feb 11]. https://www.chinacdc.cn/yw_9324/201712/t20171220_156991.html.