2,082
Views
1
CrossRef citations to date
0
Altmetric
HPV – Research Article

Healthcare providers’ practice protocols, strategies, and needed tools to address parental HPV vaccine hesitancy: An exploratory study

, , , , , , , & show all
Article: 2136862 | Received 04 Aug 2022, Accepted 11 Oct 2022, Published online: 14 Nov 2022

References

  • Palefsky JM, Giuliano AR, Goldstone S, Moreira ED, Aranda C, Jessen H, Hillman R, Ferris D, Coutlee F, Stoler MH, et al. HPV vaccine against anal HPV infection and anal intraepithelial neoplasia. N Engl J Med. Oct 27 2011;365(17):1–11. doi:10.1056/NEJMoa1010971.
  • Giuliano AR, Palefsky JM, Goldstone S, Moreira ED, Penny ME, Aranda C, Vardas E, Moi H, Jessen H, Hillman R, et al. Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males. N Engl J Med. Feb 3 2011;364(5):401–11. doi:10.1056/NEJMoa0909537.
  • Kreimer AR, González P, Katki HA, Porras C, Schiffman M, Rodriguez AC, Solomon D, Jiménez S, Schiller JT, Lowy DR, et al. Efficacy of a bivalent HPV 16/18 vaccine against anal HPV 16/18 infection among young women: a nested analysis within the Costa Rica vaccine trial. Lancet Oncol. 2011 Sep;12(9):862–70. doi:10.1016/s1470-2045(11)70213-3.
  • Herrero R, Quint W, Hildesheim A, Gonzalez, P, Struijk, L, Katki, HA, Porras, C, Schiffman, M, Rodriguez, AC, Solomon, D, et al. Reduced prevalence of oral human papillomavirus (HPV) 4 years after bivalent HPV vaccination in a randomized clinical trial in Costa Rica. PLoS One. 2013;8(7):e68329. doi:10.1371/journal.pone.0068329.
  • FUTUREI/IIStudyGroup,Dillner J, Kjaer SK, Wheeler, CM, Sigurdsson, K, Iverson, OE, Hernandez-Avila, M, Perez, G, Brown, DR, Koutsky, LA, et al. Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial. BMJ. Jul 20 2010;341:c3493. doi:10.1136/bmj.c3493.
  • Centers for Disease Control and Prevention. HPV cancers are preventable. DHHS. Accessed September 22, 2022. https://www.cdc.gov/hpv/hcp/protecting-patients.html
  • Saraiya M, Unger ER, Thompson TD, Lynch CF, Hernandez BY, Lyu CW, Steinau M, Watson M, Wilkinson EJ, Hopenhayn C, et al. US assessment of HPV types in cancers: implications for current and 9-valent HPV vaccines. J Natl Cancer Inst. 2015 Jun;107(6):djv086. doi:10.1093/jnci/djv086.
  • Viens LJ, Henley SJ, Watson M, Markowitz LE, Thomas CC, Thompson TD, Razzaghi H, Saraiya M. Human Papillomavirus–associated cancers — United States, 2008–2012. MMWR Morb Mortal Wkly Rep. Jul 8 2016;65(26):661–66. doi:10.15585/mmwr.mm6526a1.
  • Pingali C, Yankey D, Elam-Evans LD, Markowitz LE, Valier MR, Fredua B, Crowe SJ, Stokley S, Singleton JA. National vaccination coverage among adolescents aged 13–17 years — national immunization survey-teen, United States, 2021. MMWR Morb Mortal Wkly Rep. Sep 2 2022;71(35):1101–08. doi:10.15585/mmwr.mm7135a1.
  • Saxena K, Marden JR, Carias C, Bhatti, A, Patterson-Lomba, O, Gomez-Lievano, A, Yao, L, Chen, YT. Impact of the COVID-19 pandemic on adolescent vaccinations: projected time to reverse deficits in routine adolescent vaccination in the United States. Curr Med Res Opin. 2021;37(12):2077–87. [Accessed 2021 Dec 02]. doi:10.1080/03007995.2021.1981842.
  • Pingali C, Yankey D, Elam-Evans LD, Markowitz LE, Williams CL, Fredua B, McNamara LA, Stokley S, Singleton JA. National, regional, state, and selected local area vaccination coverage among adolescents aged 13–17 years — United States, 2020. MMWR Morb Mortal Wkly Rep. Sep 3 2021;70(35):1183–90. doi:10.15585/mmwr.mm7035a1.
  • Rositch AF, Liu T, Chao C, Moran M, Beavis AL. Levels of parental human papillomavirus vaccine hesitancy and their reasons for not intending to vaccinate: insights from the 2019 National Immunization Survey-Teen. J Adolesc Health. 2022 Jul;71(1):39–46. doi:10.1016/j.jadohealth.2022.01.223.
  • Szilagyi PG, Albertin CS, Gurfinkel D, Saville AW, Vangala S, Rice JD, Helmkamp L, Zimet GD, Valderrama R, Breck A, et al. Prevalence and characteristics of HPV vaccine hesitancy among parents of adolescents across the US. Vaccine. Aug 27 2020;38(38):6027–37. doi:10.1016/j.vaccine.2020.06.074.
  • Tsui J, Martinez B, Shin MB, Allee-Munoz A, Rodriguez I, Navarro J, Thomas-Barrios KR, Kast WM, Baezconde-Garbanati L. Understanding medical mistrust and HPV vaccine hesitancy among multiethnic parents in Los Angeles. J Behav Med. Feb 2 2022;1–16. doi:10.1007/s10865-022-00283-9.
  • MacDonald NE. Vaccine hesitancy: definition, scope and determinants. Vaccine. Aug 14 2015;33(34):4161–64. doi:10.1016/j.vaccine.2015.04.036.
  • McRee AL, Gilkey MB, Dempsey AF. HPV vaccine hesitancy: findings from a statewide survey of health care providers. J Pediatr Health Care. 2014 Nov-Dec;28(6):541–49. doi:10.1016/j.pedhc.2014.05.003.
  • Vadaparampil ST, Malo TL, Sutton SK, Ali KN, Kahn JA, Casler A, Salmon D, Walkosz B, Roetzheim RG, Zimet GD, et al. Missing the target for routine human papillomavirus vaccination: consistent and strong physician recommendations are lacking for 11- to 12-year-old males. Cancer Epidemiol Biomarkers Prev. 2016 Oct;25(10):1435–46. doi:10.1158/1055-9965.Epi-15-1294.
  • Hopfer S, Wright ME, Pellman H, Wasserman R, Fiks AG. HPV vaccine recommendation profiles among a national network of pediatric practitioners: understanding contributors to parental vaccine hesitancy and acceptance. Hum Vaccin Immunother. 2019;15(7–8):1776–83. doi:10.1080/21645515.2018.1560771.
  • Edwards KM, Hackell JM. Countering vaccine hesitancy. Pediatrics. 2016 Sep;138(3). doi:10.1542/peds.2016-2146
  • Opel DJ, Zhou C, Robinson JD, Henrikson N, Lepere K, Mangione-Smith R, Taylor JA. Impact of childhood vaccine discussion format over time on immunization status. Acad Pediatr. 2018 May-Jun;18(4):430–36. doi:10.1016/j.acap.2017.12.009.
  • Brewer NT, Hall ME, Malo TL, Gilkey MB, Quinn B, Lathren C. Announcements versus conversations to improve HPV vaccination coverage: a randomized trial. Pediatrics. 2017 Jan;139(1). doi:10.1542/peds.2016-1764
  • Reno JE, O’Leary S, Garrett K, Pyrzanowski J, Lockhart S, Campagna E, Barnard J, Dempsey AF. Improving provider communication about HPV vaccines for vaccine-hesitant parents through the use of motivational interviewing. J Health Commun. 2018;23(4):313–20. doi:10.1080/10810730.2018.1442530.
  • Kornides ML, McRee AL, Gilkey MB. Parents who decline HPV vaccination: who later accepts and why? Acad Pediatr. 2018 Mar;18(2s):S37–s43. doi:10.1016/j.acap.2017.06.008.
  • Margolis MA, Brewer NT, Boynton MH, Lafata JE, Southwell BG, Gilkey MB. Provider response and follow-up to parental declination of HPV vaccination. Vaccine. Jan 21 2022;40(2):344–50. doi:10.1016/j.vaccine.2021.11.055.
  • Gilkey MB, Malo TL, Shah PD, Hall ME, Brewer NT. Quality of physician communication about human papillomavirus vaccine: findings from a national survey. Cancer Epidemiol Biomarkers Prev. 2015 Nov;24(11):1673–79. doi:10.1158/1055-9965.Epi-15-0326.
  • Ellingson MK, Bednarczyk RA, O’Leary ST, Schwartz JL, Shapiro ED, Niccolai LM. Understanding the factors influencing health care provider recommendations about adolescent vaccines: a proposed framework. J Behav Med. 2022 [Accessed 2022 Feb 22]. doi:10.1007/s10865-022-00296-4.
  • Cunningham-Erves J, Koyama T, Huang Y, Jones J, Wilkins CH, Harnack L, McAfee C, Hull PC. Providers’ perceptions of parental human papillomavirus vaccine hesitancy: cross-sectional study. JMIR Cancer. Jul 2 2019;5(2):e13832. doi:10.2196/13832.
  • Kempe A, Daley MF, McCauley MM, Crane LA, Suh CA, Kennedy AM, Basket MM, Stokley SK, Dong F, Babbel CI, et al. Prevalence of parental concerns about childhood vaccines: the experience of primary care physicians. Am J Prev Med. 2011 May;40(5):548–55. doi:10.1016/j.amepre.2010.12.025.
  • Williams JTB, O’Leary ST, Nussbaum AM. Caring for the vaccine-hesitant family: evidence-based alternatives to dismissal. J Pediatr. 2020 Sep;224:137–40. doi:10.1016/j.jpeds.2020.05.029.
  • Sturm L, Donahue K, Kasting M, Kulkarni A, Brewer NT, Zimet GD. Pediatrician-parent conversations about human papillomavirus vaccination: an analysis of audio recordings. J Adolesc Health. 2017 Aug;61(2):246–51. doi:10.1016/j.jadohealth.2017.02.006.
  • Kirkpatrick DH, Burkman RT. Does standardization of care through clinical guidelines improve outcomes and reduce medical liability? Obstet Gynecol. 2010 Nov;116(5):1022–26. doi:10.1097/AOG.0b013e3181f97c62.
  • Woolf SH, Grol R, Hutchinson A, Eccles M, Grimshaw J. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ. Feb 20 1999;318(7182):527–30. doi:10.1136/bmj.318.7182.527.
  • Heymann T. Clinical protocols are key to quality health care delivery. Int J Health Care Qual Assur. 1994;7(7):14–17. doi:10.1108/09526869410074702.
  • Bundy DG, Persing NM, Solomon BS, King TM, Murakami PN, Thompson RE, Engineer LD, Lehmann CU, Miller MR. Improving immunization delivery using an electronic health record: the ImmProve project. Acad Pediatr. 2013 Sep-Oct;13(5):458–65. doi:10.1016/j.acap.2013.03.004.
  • Mayne SL, du Rivage NE, Feemster KA, Localio AR, Grundmeier RW, Fiks AG, duRivage NE. Effect of decision support on missed opportunities for human papillomavirus vaccination. Am J Prev Med. 2014 Dec;47(6):734–44. doi:10.1016/j.amepre.2014.08.010.
  • Fontenot HB, Kornides ML, McRee AL, Gilkey MB. Importance of a team approach to recommending the human papillomavirus vaccination. J Am Assoc Nurse Pract. 2018 Jul;30(7):368–72. doi:10.1097/jxx.0000000000000064.
  • Tsui J, Vincent A, Anuforo B, Btoush R, Crabtree BF. Understanding primary care physician perspectives on recommending HPV vaccination and addressing vaccine hesitancy. Hum Vaccin Immunother. Jul 3 2021;17(7):1961–67. doi:10.1080/21645515.2020.1854603
  • DeJonckheere M, Vaughn LM. Semistructured interviewing in primary care research: a balance of relationship and rigour. Fam Med Community Health. 2019;7(2):e000057. doi:10.1136/fmch-2018-000057.
  • Creswell J. Qualitative inquiry and research design: chooosing among five traditions. Newbury Park, California: Sage Publications; 1998.
  • Gilkey MB, Magnus BE, Reiter PL, McRee AL, Dempsey AF, Brewer NT. The vaccination confidence scale: a brief measure of parents’ vaccination beliefs. Vaccine. Oct 29 2014;32(47):6259–65. doi:10.1016/j.vaccine.2014.09.007
  • Creswell JW, Plano-Clark VL. Designing and conducting mixed method research, 3rd ed. Newbury Park, California: Sage Publications; 2011.
  • Palinkas LA, Horwitz SM, Green CA, Wisdom JP, Duan N, Hoagwood K. Purposeful sampling for qualitative data collection and analysis in mixed method implementation research. Adm Policy Ment Health. 2015 Sep;42(5):533–44. doi:10.1007/s10488-013-0528-y.
  • Guest G, Bunce A, Johnson L. How many interviews are enough?: an experiment with data saturation and variability. Field Methods. 2006;18(1):59–82. [Accessed 2006 Feb 01]. doi:10.1177/1525822X05279903.
  • Hagaman AK, Wutich A. How many interviews are enough to identify metathemes in multisited and cross-cultural research? Another perspective on guest, Bunce, and Johnson’s (2006) landmark study. Field Methods. 2016;29(1):23–41. [Accessed 2017 Feb 01]. doi:10.1177/1525822X16640447.
  • Morse JM Designing funded qualitative research. In: Denzin NK, and Lincoln YS, Handbook of qualitative research. Newbury Park, California: Newbury Park; 1994. pp. 230–35.
  • Hennink MM, Kaiser BN, Marconi VC. Code saturation versus meaning saturation: how many interviews are enough? Qual Health Res. 2017 Mar;27(4):591–608. doi:10.1177/1049732316665344.
  • Goddard AF, Patel M. The changing face of medical professionalism and the impact of COVID-19. Lancet. Mar 13 2021;397(10278):950–52. doi:10.1016/s0140-6736(21)00436-0
  • Borgiel AE, Dunn EV, Lamont CT, MACDONALD PJ, EVENSEN MK, BASS MJ, SPASOFF RA, WILLIAMS J. Recruiting family physicians as participants in research. Fam Pract. 1989 Sep;6(3):168–72. doi:10.1093/fampra/6.3.168.
  • Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O’Neal L, McLeod L, Delacqua G, Delacqua F, Kirby J, et al. The REDCap consortium: building an international community of software platform partners. J Biomed Inform. 2019 Jul;95:103208. doi:10.1016/j.jbi.2019.103208.
  • Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. 2007;19(6):349–57. doi:10.1093/intqhc/mzm042.
  • Morse JM. Critical analysis of strategies for determining rigor in qualitative inquiry. Qual Health Res. 2015 Sep;25(9):1212–22. doi:10.1177/1049732315588501.
  • Gilkey MB, Bednarczyk RA, Gerend MA, Kornides ML, Perkins RB, Saslow D, Sienko J, Zimet GD, Brewer NT. Getting human papillomavirus vaccination back on track: protecting our national investment in human papillomavirus vaccination in the COVID-19 era. J Adolesc Health. 2020 Nov;67(5):633–34. doi:10.1016/j.jadohealth.2020.08.013.
  • Olagoke AA, Carnahan LR, Olagoke O, Molina Y. Shared determinants for human papillomavirus and COVID-19 vaccination intention: an opportunity for resource consolidation. Am J Health Promot. 2022 Mar;36(3):506–09. doi:10.1177/08901171211053933.
  • Gilkey MB, Calo WA, Moss JL, Shah PD, Marciniak MW, Brewer NT. Provider communication and HPV vaccination: the impact of recommendation quality. Vaccine. Feb 24 2016;34(9):1187–92. doi:10.1016/j.vaccine.2016.01.023.
  • O’Leary S, Nyquist A. Why AAP recommends initiating HPV vaccination as early as age 9. Accessed July 16, 2022. https://www.aappublications.org/news/2019/10/04/hpv100419.
  • Kong WY, Huang Q, Thompson P, Grabert BK, Brewer NT, Gilkey MB. Recommending human papillomavirus vaccination at age 9: a national survey of primary care professionals. Acad Pediatr. 2022 May-Jun;22(4):573–80. doi:10.1016/j.acap.2022.01.008.
  • Lin C, Mullen J, Smith D, Kotarba M, Kaplan SJ, Tu P. Healthcare providers’ vaccine perceptions, hesitancy, and recommendation to patients: a systematic review. Vaccines (Basel). Jul 1 2021;9(7). doi:10.3390/vaccines9070713.
  • Biancarelli DL, Drainoni ML, Perkins RB. Provider experience recommending hpv vaccination before age 11 years. J Pediatr. 2020 Feb;217:92–97. doi:10.1016/j.jpeds.2019.10.025.
  • Gilkey MB, McRee AL. Provider communication about HPV vaccination: a systematic review. Hum Vaccin Immunother. Jun 2 2016;12(6):1454–68. doi:10.1080/21645515.2015.1129090
  • Perkins RB, Fisher-Borne M, Brewer NT. Engaging parents around vaccine confidence: proceedings from the national HPV vaccination roundtable meetings. Hum Vaccin Immunother. 2019;15(7–8):1639–40. doi:10.1080/21645515.2018.1520592.
  • Sundstrom B, Cartmell KB, White AA, Russo N, Well H, Pierce JY, Brandt HM, Roberts JR, Ford ME. HPV vaccination champions: evaluating a technology-mediated intervention for parents. Front Digit Health. 2021;3:636161. doi:10.3389/fdgth.2021.636161.
  • Karafillakis E, Peretti-Watel P, Verger P, Chantler T, Larson HJ. The role of maturity in adolescent decision-making around HPV vaccination in France. Vaccine. Sep 24 2021;39(40):5741–47. doi:10.1016/j.vaccine.2021.08.096.
  • Berenson AB, Laz TH, Hirth JM, McGrath CJ, Rahman M. Effect of the decision-making process in the family on HPV vaccination rates among adolescents 9-17 years of age. Hum Vaccin Immunother. 2014;10(7):1807–11. doi:10.4161/hv.28779.
  • Gamble HL, Klosky JL, Parra GR, Randolph ME. Factors influencing familial decision-making regarding human papillomavirus vaccination. J Pediatr Psychol. 2010 Aug;35(7):704–15. doi:10.1093/jpepsy/jsp108.
  • Alexander AB, Stupiansky NW, Ott MA, Herbenick D, Reece M, Zimet GD. Parent-son decision-making about human papillomavirus vaccination: a qualitative analysis. BMC Pediatr. 2012;12(1):192. [Accessed 2012 Dec 14]. doi:10.1186/1471-2431-12-192.
  • Herman R, McNutt LA, Mehta M, Salmon DA, Bednarczyk RA, Shaw J. Vaccination perspectives among adolescents and their desired role in the decision-making process. Hum Vaccin Immunother. 2019;15(7–8):1752–59. doi:10.1080/21645515.2019.1571891.