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Human Vaccines & Immunotherapeutics Volume 19, 2023 - Issue 1
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Technology

Evaluation of the self-administration potential of high-density microarray patches to human skin: A preliminary study

B. Bakera Vaxxas Biomedical Facility, Hamilton, AustraliaView further author information
,
E. Hackera Vaxxas Biomedical Facility, Hamilton, Australia;b Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, AustraliaView further author information
,
G. Sillerc Dermatology Research Centre, University of Queensland Diamantina Institute, Brisbane, Queensland, Australia;d Central Brisbane Dermatology, Brisbane, Queensland, Australia;e Department of Dermatology, Princess Alexandra Hospital, Brisbane, Queensland, AustraliaView further author information
,
M. Leef Biodock Inc, Austin, TX, USAView further author information
,
N. Mursaliyevf Biodock Inc, Austin, TX, USAView further author information
&
A. Forstera Vaxxas Biomedical Facility, Hamilton, AustraliaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5363-2015View further author information
ORCID Icon
Article: 2189409 | Received 20 Dec 2022, Accepted 07 Mar 2023, Published online: 22 Mar 2023

References

  • Wouters OJ, Shadlen KC, Salcher-Konrad M, Pollard AJ, Larson HJ, Teerawattananon Y, Jit M. Challenges in ensuring global access to COVID-19 vaccines: production, affordability, allocation, and deployment. Lancet. 2021;397(10278):1023–6. doi:10.1016/S0140-6736(21)00306-8.
  • Davies C, Taba M, Deng L, Karatas C, Bag S, Ross C, Forster A, Booy R, Skinner SR. Usability, acceptability, and feasibility of a High-Density Microarray Patch (HD-MAP) applicator as a delivery method for vaccination in clinical settings. Hum Vaccin Immunother. 2022;18(4):2018863. doi:10.1080/21645515.2021.2018863.
  • Forster AH, Witham K, Depelsenaire ACI, Veitch M, Wells JW, Wheatley A, Pryor M, Lickliter JD, Francis B, Rockman S, et al. Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: results from a randomized, controlled phase I clinical trial. PLoS Med. 2020;17(3):e1003024. doi:10.1371/journal.pmed.1003024.
  • Rouphael NG, Paine M, Mosley R, Henry S, McAllister DV, Kalluri H, Pewin W, Frew PM, Yu T, Thornburg NJ, et al. The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial. Lancet. 2017;390(10095):649–58. doi:10.1016/S0140-6736(17)30575-5.
  • Norman JJ, Arya JM, McClain MA, Frew PM, Meltzer MI, Prausnitz MR. Microneedle patches: usability and acceptability for self-vaccination against influenza. Vaccine. 2014;32(16):1856–62. doi:10.1016/j.vaccine.2014.01.076.
  • Becker L, Whorley M, Hess T, Payne H, Snow B, Von Eisebrg M. Estimating the economic and public health impact of microarray patch (MAP)-administered vaccines in pandemics. 2022.
  • Prow TW, Chen X, Prow NA, Fernando GJ, Tan CS, Raphael AP, Chang D, Ruutu MP, Jenkins DWK, Pyke A, et al. Nanopatch-targeted skin vaccination against West Nile Virus and Chikungunya virus in mice. Small. 2010;6(16):1776–84. doi:10.1002/smll.201000331.
  • Rueden CT, Schindelin J, Hiner MC, DeZonia BE, Walter AE, Arena ET, Eliceiri KW. ImageJ2: ImageJ for the next generation of scientific image data. BMC Bioinform. 2017;18(1):529. doi:10.1186/s12859-017-1934-z.
  • Biodock. AI Software Platform. 2022. www.biodock.ai.
  • Fernando GJP, Hickling J, Jayashi Flores CM, Griffin P, Anderson CD, Skinner SR, Davies C, Witham K, Pryor M, Bodle J, et al. Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™). Vaccine. 2018;36(26):3779–88. doi:10.1016/j.vaccine.2018.05.053.
  • Badizadegan K, Goodson JL, Rota PA, Thompson KM. The potential role of using vaccine patches to induce immunity: platform and pathways to innovation and commercialization. Expert Rev Vaccines. 2020;19(2):175–94. doi:10.1080/14760584.2020.1732215.
  • Sandby-Moller J, Poulsen T, Wulf HC. Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits. Acta Derm Venereol. 2003;83(6):410–3. doi:10.1080/00015550310015419.
  • Depelsenaire ACI, Witham K, Veitch M, Wells JW, Anderson CD, Lickliter JD, Rockman S, Bodle J, Treasure P, Hickling J, et al. Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trial. PLoS One. 2021;16(7):e0255282. doi:10.1371/journal.pone.0255282.
  • Siemund I, Dahlin J, Hindsen M, Zimerson E, Antelmi A, Hamnerius N, Hauksson I, Isaksson M, Pontén A, Mowitz M, et al. Contact allergy to two aluminum salts in consecutively patch-tested dermatitis patients. Dermatitis. 2022;33(1):31–35. doi:10.1097/DER.0000000000000787.
  • Hollander JE, Carr BG. Virtually perfect? Telemedicine for Covid-19. N Engl J Med. 2020;382(18):1679–81. doi:10.1056/NEJMp2003539.
  • O’Shea J, Prausnitz MR, Rouphael N. Dissolvable microneedle patches to enable increased access to vaccines against SARS-CoV-2 and future pandemic outbreaks. Vaccines (Basel). 2021;9(4):320. doi:10.3390/vaccines9040320.
  • Nguyen TT, Oh Y, Kim Y, Shin Y, Baek SK, Park JH. Progress in microneedle array patch (MAP) for vaccine delivery. Hum Vaccin Immunother. 2021;17(1):316–27. doi:10.1080/21645515.2020.1767997.
  • Forster A, Junger M. Opportunities and challenges for commercializing microarray patches for vaccination from a MAP developer’s perspective. Hum Vaccin Immunother. 2022;18(4):2050123. doi:10.1080/21645515.2022.2050123.
  • Creelman B, Frivold C, Jessup S, Saxon G, Jarrahian C. Manufacturing readiness assessment for evaluation of the microneedle array patch industry: an exploration of barriers to full-scale manufacturing. Drug Deliv Transl Res. 2022;12(2):368–75. doi:10.1007/s13346-021-01076-4.

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