Baicalin suppresses lung cancer growth phenotypes via miR-340-5p/NET1 axis

References

• Didkowska J, Wojciechowska U, Mańczuk M, et al. Lung cancer epidemiology: contemporary and future challenges worldwide. Ann Transl Med. 2016;4(8):150.
   PubMed Web of Science ®Google Scholar
• Cruz CSD, Tanoue LT, Matthay RA. Lung cancer: epidemiology, etiology, and prevention. Clin Chest Med. 2011;32(4):605–644.
   PubMed Web of Science ®Google Scholar
• Barta JA, Powell CA, Wisnivesky JP. Global epidemiology of lung cancer. Ann Glob Health. 2019;85(1). DOI:10.5334/aogh.2419
   PubMed Web of Science ®Google Scholar
• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Bade BC, Cruz CSD. Lung cancer 2020: epidemiology, etiology, and prevention. Clin Chest Med. 2020;41(1):1–24.
   PubMed Web of Science ®Google Scholar
• Tang JL, Liu BY, Ma KW. Traditional chinese medicine. Lancet. 2008;372(9654):1938–1940.
   PubMed Web of Science ®Google Scholar
• Xiang Y, Guo Z, Zhu P, et al. Traditional Chinese medicine as a cancer treatment: modern perspectives of ancient but advanced science. Cancer Med. 2019;8(5):1958–1975.
   PubMed Web of Science ®Google Scholar
• Yan Z, Lai Z, Lin J. Anticancer properties of traditional Chinese medicine. Combin Chem High Through Screen. 2017;20(5):423–429.
   PubMed Web of Science ®Google Scholar
• Gao G, Liang X, Ma W. Sinomenine restrains breast cancer cells proliferation, migration and invasion via modulation of miR-29/PDCD-4 axis. Artif Cells Nanomed Biotechnol. 2019;47(1):3839–3846.
   PubMed Web of Science ®Google Scholar
• Yu C, Chen D, Liu H, et al. Rosmarinic acid reduces the resistance of gastric carcinoma cells to 5-fluorouracil by downregulating FOXO4-targeting miR-6785-5p. Biomed Pharmacother. 2019;109:2327–2334.
   PubMed Web of Science ®Google Scholar
• Cui X, Jiang X, Wei C, et al. Astragaloside IV suppresses development of hepatocellular carcinoma by regulating miR-150-5p/β-catenin axis. Environ Toxicol Pharmacol. 2020;78:103397.
   PubMed Web of Science ®Google Scholar
• Tao Y, Zhan S, Wang Y, et al. Baicalin, the major component of traditional Chinese medicine Scutellaria baicalensis induces colon cancer cell apoptosis through inhibition of oncomiRNAs. Sci Rep. 2018;8(1):1–11.
   PubMedGoogle Scholar
• De Oliveira MR, Nabavi SF, Habtemariam S, et al. The effects of baicalein and baicalin on mitochondrial function and dynamics: a review. Pharmacol Res. 2015;100:296–308.
   PubMed Web of Science ®Google Scholar
• Waisundara VY, Hsu A, Tan BKH, et al. Baicalin improves antioxidant status of streptozotocin-induced diabetic Wistar rats. J Agric Food Chem. 2009;57(10):4096–4102.
   PubMed Web of Science ®Google Scholar
• Yang X, Zhang Q, Gao Z, et al. Baicalin alleviates IL-1β-induced inflammatory injury via down-regulating miR-126 in chondrocytes. Biomed Pharmacother. 2018;99:184–190.
   PubMed Web of Science ®Google Scholar
• Wang Z, Ma L, Su M, et al. Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling. Cell Death Dis. 2018;9(2):1–17.
   PubMedGoogle Scholar
• Yu Z, Zhan C, Du H, et al. Baicalin suppresses the cell cycle progression and proliferation of prostate cancer cells through the CDK6/FOXM1 axis. Mol Cell Biochem. 2020;469:169–178.
   PubMed Web of Science ®Google Scholar
• Sui X, Han X, Chen P, et al. Baicalin induces apoptosis and suppresses the cell cycle progression of lung cancer cells through downregulating Akt/mTOR signaling pathway. Front Mol Biosci. 2020;7:323.
   Web of Science ®Google Scholar
• Agarwal V, Bell GW, Nam JW, et al. Predicting effective microRNA target sites in mammalian mRNAs. elife. 2015;4:e05005.
   PubMed Web of Science ®Google Scholar
• Paraskevopoulou MD, Georgakilas G, Kostoulas N, et al. DIANA-microT web server v5. 0: service integration into miRNA functional analysis workflows. Nucleic Acids Res. 2013;41(W1):W169–W173.
   PubMed Web of Science ®Google Scholar
• Huang HY, Lin YCD, Li J, et al. miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database. Nucleic Acids Res. 2020;48(D1):D148–D154.
   PubMed Web of Science ®Google Scholar
• Wong N, Wang X. miRDB: an online resource for microRNA target prediction and functional annotations. Nucleic Acids Res. 2015;43(D1):D146–D152.
   PubMed Web of Science ®Google Scholar
• Huang Q, Zhang J, Peng J, et al. Effect of baicalin on proliferation and apoptosis in pancreatic cancer cells. Am J Transl Res. 2019;11(9):5645.
   PubMed Web of Science ®Google Scholar
• Chen J, Li Z, Chen AY, et al. Inhibitory effect of baicalin and baicalein on ovarian cancer cells. Int J Mol Sci. 2013;14(3):6012–6025.
   PubMed Web of Science ®Google Scholar
• Chen S, Ruan Q, Bedner E, et al. Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines. Cell Prolif. 2001;34(5):293–304.
   PubMed Web of Science ®Google Scholar
• Diao X, Yang D, Chen Y, et al. Baicalin suppresses lung cancer growth by targeting PDZ-binding kinase/T-LAK cell-originated protein kinase. Biosci Rep. 2019;39(4). DOI:10.1042/BSR20181692.
   PubMedGoogle Scholar
• You J, Cheng J, Yu B, et al. Baicalin, a Chinese herbal medicine, inhibits the proliferation and migration of human non-small cell lung carcinoma (NSCLC) cells, A549 and H1299, by activating the SIRT1/AMPK signaling pathway. Med Sci Monit. 2018;24:2126.
   PubMed Web of Science ®Google Scholar
• Duan Z, Yu AM. Bioengineered non-coding RNA agent (BERA) in action. Bioengineered. 2016;7(6):411–417.
   PubMed Web of Science ®Google Scholar
• Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–297.
   PubMed Web of Science ®Google Scholar
• Petit AP, Garcia-Petit C, Bueren-Calabuig JA, et al. A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot. J Biol Chem. 2018;293(23):9064–9077.
   PubMed Web of Science ®Google Scholar
• Sun H, Zhang Z, Luo W, et al. NET1 enhances proliferation and chemoresistance in acute lymphoblastic leukemia cells. Oncol Res. 2019;27(8):935–944.
   PubMed Web of Science ®Google Scholar
• Xiao J, Niu S, Zhu J, et al. miR-22-3p enhances multi-chemoresistance by targeting NET1 in bladder cancer cells. Oncol Rep. 2018;39(6):2731–2740.
   PubMed Web of Science ®Google Scholar
• Zong W, Feng W, Jiang Y, et al. LncRNA CTC-497E21. 4 promotes the progression of gastric cancer via modulating miR-22/NET1 axis through RhoA signaling pathway. Gastric Cancer. 2020;23(2):228–240.
   PubMed Web of Science ®Google Scholar