1,803
Views
29
CrossRef citations to date
0
Altmetric
Research Paper

MicroRNA miR-126 attenuates brain injury in septic rats via NF-κB signaling pathway

, , , , , , , & show all
Pages 2639-2648 | Received 13 Apr 2021, Accepted 29 May 2021, Published online: 11 Jun 2021

References

  • Maloney PJ. Sepsis and septic shock. Emerg Med Clin North Am. 2013;31(3):583–600.
  • Xu H, Qi Q, Yan X. Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model. Naunyn Schmiedebergs Arch Pharmacol. 2021;394(1):165–175.
  • Golzari SE, Mahmoodpoor A. Sepsis-associated encephalopathy versus sepsis-induced encephalopathy. Lancet Neurol. 2014;13(10):967–968.
  • Wilson JX, Young GB. Progress in clinical neurosciences: sepsis-associated encephalopathy: evolving concepts. Can J Neurol Sci. 2003;30(2):98–105.
  • Lipcsey M, Castegren M, Bellomo R. Hemodynamic management of septic shock. Minerva Anestesiol. 2015;81(11):1262–1272.
  • Orosz E, Kiss I, Gyöngyi Z, et al. Expression of circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a comparison of colonic and rectal cancer. In Vivo. 2018;32(6):1333–1337.
  • Lin Y, Ding Y, Song S, et al. Expression patterns and prognostic value of miR-210, miR-494, and miR-205 in middle-aged and old patients with sepsis-induced acute kidney injury. Bosn J Basic Med Sci. 2019;19:249–256.
  • Chen Y, Qiu J, Chen B, et al. Long non-coding RNA NEAT1 plays an important role in sepsis-induced acute kidney injury by targeting miR-204 and modulating the NF-κB pathway. Int Immunopharmacol. 2018;59:252–260.
  • Tong L, Tang C, Cai C, et al. Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis. Bioengineered. 2020;11(1):1334–1349.
  • Song W, Zhang T, Yang N, et al. Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1. Bioengineered. 2021;12(1):1902–1915.
  • Chen C, Zhang L, Huang H, et al. Serum miR-126-3p level is down-regulated in sepsis patients. Int J Clin Exp Pathol. 2018;11(5):2605–2612.
  • Wang HF, Wang YQ, Dou L, et al. Influences of up-regulation of miR-126 on septic inflammation and prognosis through AKT/Rac1 signaling pathway. Eur Rev Med Pharmacol Sci. 2019;23(5):2132–2138.
  • Dai R, Phillips RA, Ahmed SA. Despite inhibition of nuclear localization of NF-kappa B p65, c-Rel, and RelB, 17-beta estradiol up-regulates NF-kappa B signaling in mouse splenocytes: the potential role of Bcl-3. J Immunol. 2007;179(3):1776–1783.
  • Shang X, Lin K, Yu R, et al. Resveratrol protects the myocardium in sepsis by activating the phosphatidylinositol 3-Kinases (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway and inhibiting the nuclear factor-κB (NF-κB) signaling pathway. Med Sci Monit. 2019;25:9290–9298.
  • Funahashi Y, Kato N, Masuda T, et al. miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury. Lab Invest. 2019;99(8):1130–1142.
  • Liu C-H, Hua N, Fu X, et al. Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats. BMC Cardiovasc Disord. 2018;18(1): 236–236. DOI:10.1186/s12872-018-0950-x
  • Guo H, Tang L, Xu J, et al. MicroRNA-495 serves as a diagnostic biomarker in patients with sepsis and regulates sepsis-induced inflammation and cardiac dysfunction. Eur J Med Res. 2019;24(1):37.
  • Song YM, Qian Y, Su WQ, et al. Differences in pathological changes between two rat models of severe traumatic brain injury. Neural Regen Res. 2019;14(10):1796–1804.
  • Gomes CPC, de Gonzalo-Calvo D, Toro R, et al. Non-coding RNAs and exercise: pathophysiological role and clinical application in the cardiovascular system. Clin Sci (Lond). 2018;132(9):925–942.
  • Nwafor DC, Brichacek AL, Mohammad AS, et al. Targeting the blood-brain barrier to prevent sepsis-associated cognitive impairment. J Cent Nerv Syst Dis. 2019;11:1179573519840652.
  • Pan J, Qu M, Li Y, et al. MicroRNA-126-3p/-5p overexpression attenuates blood-brain barrier disruption in a mouse model of middle cerebral artery occlusion. Stroke. 2020;51(2):619–627.
  • Fu X, Niu T, Li X. MicroRNA-126-3p attenuates intracerebral hemorrhage-induced blood-brain barrier disruption by regulating VCAM-1 expression. Front Neurosci. 2019;13:866.
  • Chepurnova DA, Samoilova EV, Anisimov AA, et al. Compounds of IL-6 receptor complex during acute lung injury. Bull Exp Biol Med. 2018;164(5):609–611.
  • Barichello T, Fortunato JJ, Vitali AM, et al. Oxidative variables in the rat brain after sepsis induced by cecal ligation and perforation. Crit Care Med. 2006;34(3):886–889.
  • Qu J, Zhao H, Li Q, et al. MST1 suppression reduces early brain injury by inhibiting the NF-κB/MMP-9 pathway after subarachnoid hemorrhage in mice. Behav Neurol. 2018;2018:6470957.
  • Tao L, Li D, Liu H, et al. Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway. Brain Res Bull. 2018;140:154–161.
  • Čebatariūnienė A, Kriaučiūnaitė K, Prunskaitė J, et al. Extracellular vesicles suppress basal and lipopolysaccharide-induced NFκB activity in human periodontal ligament stem cells. Stem Cells Dev. 2019;28(15):1037–1049.