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Research Paper

Circular RNA PLCE1 promotes epithelial mesenchymal transformation, glycolysis in colorectal cancer and M2 polarization of tumor-associated macrophages

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Pages 6243-6256 | Received 01 Sep 2021, Accepted 03 Nov 2021, Published online: 29 Mar 2022

References

  • Schreuders E, Ruco A, Rabeneck L, et al. Colorectal cancer screening: a global overview of existing programmes. Gut. 2015;64(10):1637–1649.
  • Brenner H, Kloor M, Pox C. Colorectal cancer. Lancet. 2014;383(9927):1490–1502.
  • Kaminski M, Robertson D, Senore C, et al. Optimizing the quality of colorectal cancer screening worldwide. Gastroenterology. 2020;158(2):404–417.
  • Yang M, Ha I, Lee S, et al. Ginkgolide C promotes apoptosis and abrogates metastasis of colorectal carcinoma cells by targeting Wnt/β-catenin signaling pathway. IUBMB Life. 2021;73(10):1222–1234.
  • Zou Y, Xiao F, Song L, et al. A folate-targeted PEGylated cyclodextrin-based nanoformulation achieves co-delivery of docetaxel and siRNA for colorectal cancer. Int J Pharm. 2021;606:120888.
  • Park H, Yoo S, Cho N, et al. Tumor microenvironment-adjusted prognostic implications of the KRAS mutation subtype in patients with stage III colorectal cancer treated with adjuvant FOLFOX. Sci Rep. 2021;11(1):14609.
  • Hong H, Yun N, Jeong Y, et al. Establishment of patient-derived organotypic tumor spheroid models for tumor microenvironment modeling. Cancer Med. 2021;10(16):5589–5598.
  • Boutilier A, Elsawa S. Macrophage polarization states in the tumor microenvironment. Int J Mol Sci. 2021;22(13).
  • Dora D, Rivard C, Yu H, et al. Characterization of tumor-associated macrophages and the immune microenvironment in limited-stage neuroendocrine-high and -low small cell lung cancer. Biology (Basel). 2021;19(1):10.
  • Cheong C, Mrozik K, Hewett D, et al. Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma. Cancer Lett. 2020;475:99–108.
  • Baj J, Brzozowska K, Forma A, et al. Immunological aspects of the tumor microenvironment and epithelial-mesenchymal transition in gastric carcinogenesis. Int J Mol Sci. 2020;21(7).
  • Zhang P, Huang Y, Liang X, et al. Enhancement of the antitumor effect of HER2-directed CAR-T cells through blocking epithelial-mesenchymal transition in tumor cells. FASEB J. 2020;34(8):11185–11199.
  • Lin Y, Tsai K, Chen J, et al. Mangiferin inhibits lipopolysaccharide-induced epithelial-mesenchymal transition (EMT) and enhances the expression of tumor suppressor gene PER1 in non-small cell lung cancer cells. Environ Toxicol. 2020;35(10):1070–1081.
  • Guo Y, Liu B, Liu Y, et al. Oncogenic chromatin modifier KAT2A activates MCT1 to drive the glycolytic process and tumor progression in renal cell carcinoma. Front Cell Dev Biol. 2021;9:690796.
  • Raines L, Huang S. Is glucose the scapegoat for tumor evasion? Cancer Cell. 2021;39(7):907–909.
  • Qian X, Zhao J, Yeung P, et al. Revealing lncRNA structures and interactions by sequencing-based approaches. Trends Biochem Sci. 2019;44(1):33–52.
  • Guo Y, Guo Y, Chen C, et al. Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis. Mol Cancer. 2021;20(1):93.
  • Chen J, Wu Y, Luo X, et al. Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer. Theranostics. 2021;11(15):7507–7526.
  • Liu D, Peng S, Li Y, et al. Circ-MFN2 positively regulates the proliferation, metastasis, and radioresistance of colorectal cancer by regulating the miR-574-3p/IGF1R signaling axis. Front Genet. 2021;12:671337.
  • Chen Z, Chen H, Yang L, et al. CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing. J Cell Mol Med. 2021;25(15):7244-7256.
  • Qian M, Ling W, Ruan Z. Long non-coding RNA SNHG12 promotes immune escape of ovarian cancer cells through their crosstalk with M2 macrophages. Aging (Albany NY). 2020;12(17):17122–17136.
  • Shen Z, Yin L, Zhou H, et al. Combined inhibition of AURKA and HSF1 suppresses proliferation and promotes apoptosis in hepatocellular carcinoma by activating endoplasmic reticulum stress. Cell Oncol (Dordr). 2021;44(5):1035–1049.
  • He Z, Yuan J, Shen F, et al. Atorvastatin enhances inhibitory effects of irradiation on tumor growth by reducing MSH2 expression both in prostate cancer cells and xenograft tumor models. Anticancer Agents Med Chem. 2021;21. DOI:10.2174/1871520621666210602133005.
  • Li X, Li R, Gong Q, et al. Circular RNA circVMA21 ameliorates lipopolysaccharide (LPS)-induced acute kidney injury by targeting the miR-199a-5p/NRP1 axis in sepsis.[J]. Biochem Biophys Res Commun. 2021;548:174–181.
  • Dai W, Zhai X, Chen Y, et al. CircMMP1 promotes colorectal cancer growth and metastasis by sponging miR-1238 and upregulating MMP family expression.[J]. Ann Transl Med. 2021;9(16):1341.
  • Li H, Xiong H, Xiao Y, et al. LINC02195Long non-coding RNA as a regulator of MHC I molecules and favorable prognostic marker for head and neck squamous cell carcinoma. Front Oncol. 2020;10:615.
  • Pan Y, Qin J, Sun H, et al. MiR-485-5p as a potential biomarker and tumor suppressor in human colorectal cancer. Biomark Med. 2020;14(3):239–248.
  • Pan Y, Sun H, Hu X, et al. The inhibitory role of miR‑485‑5p in colorectal cancer proliferation and invasion via targeting of CD147. Oncol Rep. 2018;39(5):2201–2208.
  • Yan Y, Xu H, Zhang L, et al. RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma. Onco Targets Ther. 2019;12:1691–1703.
  • Hu M, Fu X, Si Z, et al. Identification of differently expressed genes associated with prognosis and growth in colon adenocarcinoma based on integrated bioinformatics analysis. Front Genet. 2019;10:1245.
  • Zhang Z, Zheng S, Lin Y, et al. Genomics and prognosis analysis of epithelial-mesenchymal transition in colorectal cancer patients. BMC Cancer. 2020;20(1):1135.
  • He J, Wu F, Han Z, et al. Biomarkers (mRNAs and Non-Coding RNAs) for the diagnosis and prognosis of colorectal cancer - from the body fluid to tissue level. Front Oncol. 2021;11:632834.
  • Zhang J, Li S, Zhang X, et al. LncRNA HLA-F-AS1 promotes colorectal cancer metastasis by inducing PFN1 in colorectal cancer-derived extracellular vesicles and mediating macrophage polarization. Cancer Gene Ther. 2021;28(12):1269-1284.
  • Liang Z, Liu H, Wang F, et al. LncRNA RPPH1 promotes colorectal cancer metastasis by interacting with TUBB3 and by promoting exosomes-mediated macrophage M2 polarization. Cell Death Dis. 2019;10(11):829.
  • Zhao Y, Yu Z, Ma R, et al. lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration. Molecular Therapy - Nucleic Acids. 2021;23:536–551.
  • Ganapathy-Kanniappan S, Geschwind J. Tumor glycolysis as a target for cancer therapy: progress and prospects. Mol Cancer. 2013;12(1):152.
  • Yang J, Ren B, Yang G, et al. The enhancement of glycolysis regulates pancreatic cancer metastasis. Cell Mol Life Sci. 2020;77(2):305–321.
  • Wang X, Tao G, Huang D, et al. Circular RNA NOX4 promotes the development of colorectal cancer via the microRNA‑485‑5p/CKS1B axis. Oncol Rep. 2020;44(5):2009–2020.
  • Li Y, Zang H, Zhang X, et al. circ_0136666 facilitates the progression of colorectal cancer via miR-383/CREB1 Axis. Cancer Manag Res. 2020;12:6795–6806.
  • Li Z, Yao H, Wang S, et al. CircTADA2A suppresses the progression of colorectal cancer via miR-374a-3p/KLF14 axis. J Exp Clin Cancer Res. 2020;39(1):160.