Advanced search
Publication Cover
Bioengineered Volume 13, 2022 - Issue 2
Submit an article Journal homepage
912
Views
3
CrossRef citations to date
0
Altmetric
Research Paper

Long non-coding RNA growth arrest specific 5 is downregulated in sepsis-ALI and inhibits apoptosis by up-regulating miR-146a

Jiaqiong Lia Department of Critical Care Medicine, Xuzhou Central Hospital, Xuzhou Clinic School of Nanjing Medical University, Xuzhou City, Jiangsu Province, ChinaView further author information
,
Hongyang Xub Department of Lung Transplant Center, Wuxi People’s Hospital Affiliated to Nanjing Medical University, Wuxi City, Jiangsu Province, ChinaView further author information
,
Na Lia Department of Critical Care Medicine, Xuzhou Central Hospital, Xuzhou Clinic School of Nanjing Medical University, Xuzhou City, Jiangsu Province, ChinaView further author information
,
Wenjing Dua Department of Critical Care Medicine, Xuzhou Central Hospital, Xuzhou Clinic School of Nanjing Medical University, Xuzhou City, Jiangsu Province, ChinaView further author information
,
Junxiang Tia Department of Critical Care Medicine, Xuzhou Central Hospital, Xuzhou Clinic School of Nanjing Medical University, Xuzhou City, Jiangsu Province, ChinaView further author information
&
Jingyu Chenb Department of Lung Transplant Center, Wuxi People’s Hospital Affiliated to Nanjing Medical University, Wuxi City, Jiangsu Province, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5737-0334View further author information
ORCID Icon
Pages 4146-4152 | Received 08 Oct 2021, Accepted 30 Nov 2021, Published online: 03 Feb 2022

References

  • Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013 Aug 29;369(9):840–851.
  • Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence. 2014 Jan 1;5(1):4–11.
  • Dellinger RP, Carlet JM, Masur H, et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Intensive Care Med. 2004 Apr;30(4):536–555.
  • Churpek MM, Snyder A, Han X, et al. Quick sepsis-related organ failure assessment, systemic inflammatory response syndrome, and early warning scores for detecting clinical deterioration in infected patients outside the intensive care unit. Am J Respir Crit Care Med. 2017 Apr 1;195(7):906–911.
  • Von Bahr V, Hultman J, Eksborg S, et al. Long-term survival in adults treated with extracorporeal membrane oxygenation for respiratory failure and sepsis. Crit Care Med. 2017 Feb;45(2):164–170.
  • Czaikoski PG, Mota JM, Nascimento DC, et al. Neutrophil extracellular traps induce organ damage during experimental and clinical sepsis. PloS One. 2016;11(2):e0148142.
  • Zeng L, Kang R, and Zhu S, et al. ALK is a therapeutic target for lethal sepsis. 2017 Oct 18; 9(412):eaan5689.
  • Fani F, Regolisti G, Delsante M, et al. Recent advances in the pathogenetic mechanisms of sepsis-associated acute kidney injury. J Nephrol. 2018 Jun;31(3):351–359.
  • Englert JA, Bobba C, Baron RM. Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome. JCI Insight. 2019 Jan 24;4(2). DOI:10.1172/jci.insight.124061.
  • Manga G, Calin GA, Manuc M, et al. New definitions of sepsis and the quest for specific biomarkers. Are the miRNAs the answer? Chirurgia. 2018 Jul-Aug;113(4):464–468.
  • Chen H, Wang X, Yan X, et al. RETRACTED: lncRNA MALAT1 regulates sepsis-induced cardiac inflammation and dysfunction via interaction with miR-125b and p38 MAPK/NFκB. Int Immunopharmacol. 2018 Feb;55:69–76.
  • Remick DG, Newcomb DE, Bolgos GL, et al. Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture. Shock. 2000;13(2):110–116.
  • Li F, Sun J, Huang S, et al. LncRNA GAS5 overexpression reverses LPS-induced inflammatory injury and apoptosis through up-regulating KLF2 expression in ATDC5 chondrocytes. Cell Physiol Biochem. 2018;45(3):1241–1251.
  • Zeng Z, Gong H, Li Y, et al. Upregulation of miR-146a contributes to the suppression of inflammatory responses in LPS-induced acute lung injury. Exp Lung Res. 2013 Sep;39(7):275–282.
  • Li P, Gu L, Bian Q, et al. Long non-coding RNA MALAT1 enhances the protective effect of dexmedetomidine on acute lung injury by sponging miR-135a-5p to downregulate the ratio of X-box binding proteins XBP-1S/XBP-1U. Bioengineered. 2021;12(1):6377–6389.
  • Han J, Li S, Feng Y, et al. A novel circular RNA (hsa_circ_0059930)-mediated miRNA–mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells. Bioengineered. 2021;12(1):1739–1751.
  • Zhu L, Wei M, Yang N, et al. Glycyrrhizic acid alleviates the meconium-induced acute lung injury in neonatal rats by inhibiting oxidative stress through mediating the Keap1/Nrf2/HO-1 signal pathway. Bioengineered. 2021;12(1):2616–2626.
  • Duan Q, Jia Y, Qin Y, et al. Narciclasine attenuates LPS-induced acute lung injury in neonatal rats through suppressing inflammation and oxidative stress. Bioengineered. 2020;11(1):801–810.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.