Eukaryotic translation initiation factor 3 subunit B could serve as a potential prognostic predictor for breast cancer

References

• Harbeck N, Penault-Llorca F, Cortes J, et al. Breast cancer. Nat Rev Dis Primers. 2019;5(1):66.
   PubMed Web of Science ®Google Scholar
• Emens LA. Breast Cancer Immunotherapy: facts and Hopes. Clin Cancer Res. 2018;24(3):511–520.
   PubMed Web of Science ®Google Scholar
• Valasek LS, Zeman J, Wagner S, et al. Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle. Nucleic Acids Res. 2017;45(19):10948–10968.
   PubMed Web of Science ®Google Scholar
• Valasek LS. ‘Ribozoomin’–translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs). Curr Protein Pept Sci. 2012;13(4):305–330.
   PubMed Web of Science ®Google Scholar
• Saletta F, Suryo Rahmanto Y, Richardson DR. The translational regulator eIF3a: the tricky eIF3 subunit! Biochim Biophys Acta. 2010;1806(2):275–286.
   PubMed Web of Science ®Google Scholar
• Park HS, Himmelbach A, Browning KS, et al. A plant viral “reinitiation” factor interacts with the host translational machinery. Cell. 2001;106(6):723–733.
   PubMed Web of Science ®Google Scholar
• Mohammad MP, Munzarova Pondelickova V, Zeman J, et al. In vivo evidence that eIF3 stays bound to ribosomes elongating and terminating on short upstream ORFs to promote reinitiation. Nucleic Acids Res. 2017;45(5):2658–2674.
   PubMed Web of Science ®Google Scholar
• Schepetilnikov M, Dimitrova M, Mancera-Martinez E, et al. TOR and S6K1 promote translation reinitiation of uORF-containing mRNAs via phosphorylation of eIF3h. EMBO J. 2013;32(8):1087–1102.
   PubMed Web of Science ®Google Scholar
• Gunisova S, Hronova V, Mohammad MP, et al. Please do not recycle! Translation reinitiation in microbes and higher eukaryotes. FEMS Microbiol Rev. 2018;42(2):165–192.
   PubMed Web of Science ®Google Scholar
• Beznoskova P, Cuchalova L, Wagner S, et al. Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells. PLoS Genet. 2013;9(11):e1003962.
   PubMed Web of Science ®Google Scholar
• Pisarev AV, Hellen CU, Pestova TV. Recycling of eukaryotic posttermination ribosomal complexes. Cell. 2007;131(2):286–299.
   PubMed Web of Science ®Google Scholar
• Pisarev AV, Skabkin MA, Pisareva VP, et al. The role of ABCE1 in eukaryotic posttermination ribosomal recycling. Mol Cell. 2010;37(2):196–210.
   PubMed Web of Science ®Google Scholar
• Beznoskova P, Wagner S, Jansen ME, et al. Translation initiation factor eIF3 promotes programmed stop codon readthrough. Nucleic Acids Res. 2015;43(10):5099–5111.
   PubMed Web of Science ®Google Scholar
• Beznoskova P, Gunisova S, Valasek LS. Rules of UGA-N decoding by near-cognate tRNAs and analysis of readthrough on short uORFs in yeast. RNA. 2016;22(3):456–466.
   PubMed Web of Science ®Google Scholar
• Hershey JW. The role of eIF3 and its individual subunits in cancer. Biochim Biophys Acta. 2015;1849(7):792–800.
   PubMed Web of Science ®Google Scholar
• de La Parra C, Walters BA, Geter P, et al. Translation initiation factors and their relevance in cancer. Curr Opin Genet Dev. 2018;48:82–88.
   PubMed Web of Science ®Google Scholar
• Chu J, Cargnello M, Topisirovic I, et al. Translation Initiation Factors: reprogramming Protein Synthesis in Cancer. Trends Cell Biol. 2016;26(12):918–933.
   PubMed Web of Science ®Google Scholar
• Cuesta R, Berman A, Alayev A, et al. Estrogen receptor α promotes protein synthesis by fine-tuning the expression of the eukaryotic translation initiation factor 3 subunit f (eIF3f). J Biol Chem. 2019;294(7):2267–2278.
   PubMed Web of Science ®Google Scholar
• Wang G, Bai X, Jiang G, et al. GIT1 overexpression promotes epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma. Bioengineered. 2021;12(1):30–43.
   PubMed Web of Science ®Google Scholar
• Chen S, Wei Y, Liu H, et al. Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics. Bioengineered. 2021;12(1):127–137.
   PubMed Web of Science ®Google Scholar
• He M, Han Y, Cai C, et al. CLEC10A is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in lung adenocarcinoma. J Cell Mol Med. 2021;25(7):3391–3399.
   PubMed Web of Science ®Google Scholar
• Feng X, Zhang M, Wang B, et al. CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status. Journal of Experimental & Clinical Cancer Research: CR. 2019;38(1):361.
   PubMed Web of Science ®Google Scholar
• Tang Z, Li C, Kang B, et al. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res. 2017;45(W1):W98–W102.
   PubMed Web of Science ®Google Scholar
• Rhodes DR, Kalyana-Sundaram S, Mahavisno V, et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia. 2007;9(2):166–180.
   PubMed Web of Science ®Google Scholar
• Jezequel P, Campone M, Gouraud W, et al. bc-GenExMiner: an easy-to-use online platform for gene prognostic analyses in breast cancer. Breast Cancer Res Treat. 2012;131(3):765–775.
   PubMed Web of Science ®Google Scholar
• Györffy B, Lanczky A, Eklund A, et al. An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. Breast Cancer Res Treat. 2010;123(3):725–731.
   PubMed Web of Science ®Google Scholar
• Cerami E, Gao J, Dogrusoz U, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2(5):401–404.
   PubMed Web of Science ®Google Scholar
• Thul PJ, Lindskog C. The human protein atlas: a spatial map of the human proteome. Protein Sci. 2018;27(1):233–244.
   PubMed Web of Science ®Google Scholar
• Uhlen M, Fagerberg L, Hallstrom BM, et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347(6220):1260419.
   PubMed Web of Science ®Google Scholar
• Ta H, Wang W, Phan N, et al. Potential Therapeutic and Prognostic Values of LSM Family Genes in Breast Cancer. Cancers (Basel). 2021;13(19):4902.
   PubMed Web of Science ®Google Scholar
• Finak G, Bertos N, Pepin F, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med. 2008;14(5):518–527.
   PubMed Web of Science ®Google Scholar
• Ramaswamy S, Tamayo P, Rifkin R, et al. Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci U S A. 2001;98(26):15149–15154.
   PubMed Web of Science ®Google Scholar
• Richardson AL, Wang ZC, De Nicolo A, et al. X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell. 2006;9(2):121–132.
   PubMed Web of Science ®Google Scholar
• Ma XJ, Dahiya S, Richardson E, et al. Gene expression profiling of the tumor microenvironment during breast cancer progression. Breast Cancer Res. 2009;11(1):R7.
   PubMed Web of Science ®Google Scholar
• Qu K, Wang Z, Fan H, et al. MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma. Cell Death Dis. 2017;8(2):e2603.
   PubMedGoogle Scholar
• L J, L J, L Z, et al. Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth. Cell death disease markers. 2017;8(3):e2673.
   Google Scholar
• Zhang F, Xiang S, Cao Y, et al. EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway. Cell Death Dis. 2017;8(6):e2868.
   PubMedGoogle Scholar
• Chen HH, Yu HI, Yang MH, et al. DDX3 Activates CBC-eIF3-Mediated Translation of uORF-Containing Oncogenic mRNAs to Promote Metastasis in HNSCC. Cancer Res. 2018;78(16):4512–4523.
   PubMed Web of Science ®Google Scholar
• Liu T, Wei Q, Jin J, et al. The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation. Nucleic Acids Res. 2020;48(7):3816–3831 .
   Web of Science ®Google Scholar
• Golob-Schwarzl N, Krassnig S, Toeglhofer AM, et al. New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors. Eur J Cancer. 2017;83:56–70.
   PubMed Web of Science ®Google Scholar
• Wang L, Wen X, Luan F, et al. EIF3B is associated with poor outcomes in gastric cancer patients and promotes cancer progression via the PI3K/AKT/mTOR signaling pathway. Cancer Manag Res. 2019;11:7877–7891.
   PubMed Web of Science ®Google Scholar
• Xu F, Zhang S, Liu Z, et al. TEX9 and eIF3b functionally synergize to promote the progression of esophageal squamous cell carcinoma. BMC Cancer. 2019;19(1):875.
   PubMed Web of Science ®Google Scholar
• Ma F, Li X, Ren J, et al. Downregulation of eukaryotic translation initiation factor 3b inhibited proliferation and metastasis of gastric cancer. Cell Death Dis. 2019;10(9):623.
   PubMedGoogle Scholar
• Wang L, Ouyang L. Effects of EIF3B gene downregulation on apoptosis and proliferation of human ovarian cancer SKOV3 and HO-8910 cells. Biomed Pharmacothe. 2019;109:831–837.
   PubMed Web of Science ®Google Scholar
• Tian Y, Zhao K, Yuan L, et al. EIF3B correlates with advanced disease stages and poor prognosis, and it promotes proliferation and inhibits apoptosis in non-small cell lung cancer. Cancer Biomarkers. 2018;23(2):291–300.
   PubMed Web of Science ®Google Scholar
• Min J, Chen H. Eukaryotic initiation factor 3B downregulation suppresses cell proliferation, migration and invasion while it induces cell apoptosis by blocking the β-catenin pathway in endometrial cancer. Int J Clin Exp Pathol. 2019;12(9):3595–3603.
   PubMed Web of Science ®Google Scholar
• Cvetic C, Walter J. Getting a grip on licensing: mechanism of stable Mcm2-7 loading onto replication origins. Mol Cell. 2006;21(2):143–144.
   PubMed Web of Science ®Google Scholar
• Blow J, Hodgson B. Replication licensing–defining the proliferative state? Trends Cell Biol. 2002;12(2):72–78.
   PubMed Web of Science ®Google Scholar
• L Z, L W, L J, et al. Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells. Sci Rep. 2017;7(1):41776.
   PubMedGoogle Scholar
• Lau K, Chan Q, Pang J, et al. Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion. Oncogene. 2010;29(40):5475–5489.
   PubMed Web of Science ®Google Scholar
• Spilka R, Ernst C, Bergler H, et al. eIF3a is over-expressed in urinary bladder cancer and influences its phenotype independent of translation initiation. Cell Oncol (Dordr). 2014;37(4):253–267.
   PubMed Web of Science ®Google Scholar
• Wang SQ, Liu Y, Yao MY, et al. Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes Cell Proliferation and Motility in Pancreatic Cancer. J Korean Med Sci. 2016;31(10):1586–1594.
   PubMed Web of Science ®Google Scholar
• Hu C, Wang Y, Li A, et al. Overexpressed circ_0067934 acts as an oncogene to facilitate cervical cancer progression via the miR-545/EIF3C axis. J Cell Physiol. 2019;234(6):9225–9232.
   PubMed Web of Science ®Google Scholar
• Wang D, Jia Y, Zheng W, et al. eIF3DOverexpression of in Lung Adenocarcinoma Is a New Independent Prognostic Marker of Poor Survival. Dis Markers. 2019;2019:6019637.
   PubMed Web of Science ®Google Scholar
• Li T, Li S, Chen D, et al. Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma. Cancer Sci. 2017;108(5):877–885.
   PubMed Web of Science ®Google Scholar
• Zhao W, Li X, Wang J, et al. Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway. Med Sci Monit. 2017;23:4182–4191.
   PubMed Web of Science ®Google Scholar
• Shi J, Feng Y, Goulet AC, et al. The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis. J Biol Chem. 2003;278(7):5062–5071.
   PubMed Web of Science ®Google Scholar
• Hu Y, Wei X, Lv Y, et al. EIF3H interacts with PDCD4 enhancing lung adenocarcinoma cell metastasis. Am J Cancer Res. 2020;10(1):179–195.
   PubMed Web of Science ®Google Scholar
• Qi J, Dong Z, Liu J, et al. EIF3i promotes colon oncogenesis by regulating COX-2 protein synthesis and β-catenin activation. Oncogene. 2014;33(32):4156–4163.
   PubMed Web of Science ®Google Scholar
• Zeng L, Wan Y, Li D, et al. The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. J Biol Chem. 2013;288(42):30087–30093.
   PubMed Web of Science ®Google Scholar
• Goh S, Hong S, Hong S, et al. eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer. Oncogene. 2011;30(4):398–409.
   PubMed Web of Science ®Google Scholar
• Gluck S, Ross JS, Royce M, et al. TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumab. Breast Cancer Res Treat. 2012;132(3):781–791.
   PubMed Web of Science ®Google Scholar
• Hedenfalk I, Duggan D, Chen Y, et al. Gene-expression profiles in hereditary breast cancer. N Engl J Med. 2001;344(8):539–548.
   PubMed Web of Science ®Google Scholar
• Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003;100(14):8418–8423.
   PubMed Web of Science ®Google Scholar
• Turashvili G, Bouchal J, Baumforth K, et al. Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. BMC Cancer. 2007;7(1):55.
   PubMedGoogle Scholar
• R S, T P, R R, et al. Multiclass cancer diagnosis using tumor gene expression signatures. Proceedings of the National Academy of Sciences of the United States of America. 2001;98(26):15149–15154.
   PubMed Web of Science ®Google Scholar