1,136
Views
4
CrossRef citations to date
0
Altmetric
Research Paper

Circular RNA PIP5K1A act as microRNA-552-3p sponge to regulates inflammation, oxidative damage in glucolipotoxicity-induced pancreatic INS-1 β-cells via Janus kinase 1

Pages 5724-5736 | Received 09 Nov 2021, Accepted 20 Dec 2021, Published online: 19 Feb 2022

References

  • Li R, Sun X, Li P, et al. GLP-1-induced AMPK activation inhibits PARP-1 and promotes LXR-mediated ABCA1 expression to protect pancreatic beta-cells against cholesterol-induced toxicity through cholesterol efflux. Front Cell Dev Biol. 2021;9:646113.
  • Wu L, Xiong L, Li J, et al. Circ-Tulp4 promotes beta-cell adaptation to lipotoxicity by regulating soat1 expression. J Mol Endocrinol. 2020;65(4):149–161.
  • Alnahdi A, John A, Raza H. N-acetyl cysteine attenuates oxidative stress and glutathione-dependent redox imbalance caused by high glucose/high palmitic acid treatment in pancreatic Rin-5F cells. PLoS One. 2019;14(12):e0226696.
  • Prentki M, Corkey BE. Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? Diabetes. 1996;45(3):273–283.
  • Poitout V, Robertson RP. Minireview: secondary beta-cell failure in type 2 diabetes–a convergence of glucotoxicity and lipotoxicity. Endocrinology. 2002;143(2):339–342.
  • Meng X, Li X, Zhang P, et al. Circular RNA: an emerging key player in RNA world. Brief Bioinform. 2017;18(4):547–557.
  • Memczak S, Jens M, Elefsinioti A, et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 2013;495(7441):333–338.
  • Zheng S, Zhang X, Odame E, et al. CircRNA-protein interactions in muscle development and diseases. Int J Mol Sci. 2021;22(6):3262.
  • Guo JU, Agarwal V, Guo H, et al. Expanded identification and characterization of mammalian circular RNAs. Genome Biol. 2014;15(7):409.
  • Wang F, Zhang M. Circ_001209 aggravates diabetic retinal vascular dysfunction through regulating miR-15b-5p/COL12A1. J Transl Med. 2021;19(1):294.
  • Li Y, Zhou Y, Zhao M, et al. Differential profile of plasma circular RNAs in type 1 diabetes mellitus. Diabetes Metab J. 2020;44(6):854–865.
  • Zheng K, Xie H, Wu W, et al. CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p. Cancer Cell Int. 2021;21(1):27.
  • Song H, Xu Y, Xu T, et al. CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p. Biomed Pharmacother. 2020;126:109941.
  • Ma Y, Cong X, Zhang Y, et al. CircPIP5K1A facilitates gastric cancer progression via miR-376c-3p/ZNF146 axis. Cancer Cell Int. 2020;20(1):81.
  • Ma N, Fan L, Dong Y, et al. New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice. Pharmacol Res. 2021;167:105562.
  • Fan L, Lai R, Ma N, et al. miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder. J Hepatol. 2021;74(1):8–19.
  • Zhou Y, He H, Xu H, et al. Association of oncogenic bacteria with colorectal cancer in South China. Oncotarget. 2016;7(49):80794–80802.
  • Wang X, Dou N, Wang J, et al. FOXM1-induced miR-552 expression contributes to pancreatic cancer progression by targeting multiple tumor suppressor genes. Int J Biol Sci. 2021;17(4):915–925.
  • Zhao W, Han T, Li B, et al. miR-552 promotes ovarian cancer progression by regulating PTEN pathway. J Ovarian Res. 2019;12(1):121.
  • Sun L, Wei Y, Wang J. Circular RNA PIP5K1A (circPIP5K1A) accelerates endometriosis progression by regulating the miR-153-3p/Thymosin Beta-4 X-Linked (TMSB4X) pathway. Bioengineered. 2021;12(1):7104–7118.
  • Morris R, Kershaw NJ, Babon JJ. The molecular details of cytokine signaling via the JAK/STAT pathway. Protein Sci. 2018;27(12):1984–2009.
  • El-Assaad W, Buteau J, Peyot M-L, et al. Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology. 2003;144(9):4154–4163.
  • Ma J, Wu Y, He Y. Silencing circRNA LRP6 down-regulates PRMT1 to improve the streptozocin-induced pancreatic beta-cell injury and insulin secretion by sponging miR-9-5p. J Bioenerg Biomembr. 2021;53(3):333–342.
  • Juan-Mateu J, Rech TH, Villate O, et al. Neuron-enriched RNA-binding proteins regulate pancreatic beta cell function and survival. J Biol Chem. 2017;292(8):3466–3480.
  • Zhu XY, Guo Q, Zhu M, et al. HLX affects cell cycle and proliferation in AML cells via the JAK/STAT signaling pathway. Oncol Lett. 2020;20(2):1888–1896.
  • Maiese K. Disease onset and aging in the world of circular RNAs. J Transl Sci. 2016;2(6):327–329.
  • Xu H, Guo S, Li W, et al. The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells. Sci Rep. 2015;5(1):12453.
  • Couto FM, Minn AH, Pise-Masison CA, et al. Exenatide blocks JAK1-STAT1 in pancreatic beta cells. Metabolism. 2007;56(7):915–918.
  • Mazzoli A, Sardi C, Breasson L, et al. JNK1 ablation improves pancreatic beta-cell mass and function in db/db diabetic mice without affecting insulin sensitivity and adipose tissue inflammation. FASEB Bioadv. 2021;3(2):94–107.
  • Zhang D, Xie T, Leung PS. Irisin ameliorates glucolipotoxicity-associated beta-cell dysfunction and apoptosis via AMPK signaling and anti-inflammatory actions. Cell Physiol Biochem. 2018;51(2):924–937.
  • Latreille M, Hausser J, Stützer I, et al. MicroRNA-7a regulates pancreatic beta cell function. J Clin Invest. 2014;124(6):2722–2735.
  • Stoll L, Sobel J, Rodriguez-Trejo A, et al. Circular RNAs as novel regulators of beta-cell functions in normal and disease conditions. Mol Metab. 2018;9:69–83.
  • Cao Y, Yuan G, Zhang Y, et al. High glucose-induced circHIPK3 downregulation mediates endothelial cell injury. Biochem Biophys Res Commun. 2018;507(1–4):362–368.
  • Wang Z, Deng C, Zheng Y. Involvement of circRNAs in proinflammatory cytokines-mediated beta-cell dysfunction. Mediators Inflamm. 2021;2021:5566453.
  • Sun R, Xue W, Zhao J. Hsa_circ_0054633 mediates apoptosis and insulin secretion in human pancreatic beta cells through miR-409-3p/caspase-8 axis. Diabetes Res Clin Pract. 2021;176:108837.
  • Kulcheski FR, Christoff AP, Margis R. Circular RNAs are miRNA sponges and can be used as a new class of biomarker. J Biotechnol. 2016;238:42–51.
  • Lu J, Pang L, Zhang B, et al. Silencing circANKRD36 inhibits streptozotocin-induced insulin resistance and inflammation in diabetic rats by targeting miR-145 via XBP1. Inflamm Res. 2021;70(6):695–704.
  • Xu B, Wang Q, Li W, et al. Circular RNA circEIF4G2 aggravates renal fibrosis in diabetic nephropathy by sponging miR-218. J Cell Mol Med. 2020. DOI:10.1111/jcmm.16129.