Fumitremorgin C alleviates advanced glycation end products (AGE)-induced chondrocyte inflammation and collagen II and aggrecan degradation through sirtuin-1 (SIRT1)/nuclear factor (NF)-κB/ mitogen-activated protein kinase (MAPK)

References

• Xie C, Chen Q. Adipokines: new therapeutic target for osteoarthritis? Curr Rheumatol Rep. 2019;21(12):71.
   PubMed Web of Science ®Google Scholar
• Litwic A, Edwards MH, Dennison EM, et al. Epidemiology and burden of osteoarthritis. Br Med Bull. 2013;105(1):185–199.
   PubMed Web of Science ®Google Scholar
• Felson DT. Clinical practice. Osteoarthritis of the knee. N Engl J Med. 2006;354(8):841–848.
   PubMed Web of Science ®Google Scholar
• Xue X, Chen Y, Wang Y, et al. Troxerutin suppresses the inflammatory response in advanced glycation end-product-administered chondrocytes and attenuates mouse osteoarthritis development. Food Funct. 2019;10(8):5059–5069.
   PubMed Web of Science ®Google Scholar
• Shan W, Qi J, Li C, et al. Agonism of GPR39 displays protective effects against advanced glycation end-product (AGE)-induced degradation of extracellular matrix in human SW1353 cells. Arch Biochem Biophys. 2019;677:108164.
   PubMed Web of Science ®Google Scholar
• Deng JS, Jiang WP, Chen CC, et al. Cordyceps cicadae mycelia ameliorate cisplatin-induced acute kidney injury by suppressing the TLR4/NF-κB/MAPK and activating the HO-1/Nrf2 and Sirt-1/AMPK pathways in mice. Oxid Med Cell Longev. 2020;2020:7912763.
   PubMed Web of Science ®Google Scholar
• Liu A, Zhang B, Zhao W, et al. Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways. Bioengineered. 2021;12(1):183–195.
   PubMed Web of Science ®Google Scholar
• Xu F, Xu J, Xiong X, et al. Salidroside inhibits MAPK, NF-κB, and STAT3 pathways in psoriasis-associated oxidative stress via SIRT1 activation. Redox Rep. 2019;24(1):70–74.
   PubMedGoogle Scholar
• Shi J, Cao F, Chang Y, et al. Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1. Bioengineered. 2021;12(1):1445–1456.
   PubMed Web of Science ®Google Scholar
• Guan R, Cai Z, Wang J, et al. Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. Aging (Albany NY). 2019;11(24):11844–11864.
   PubMedGoogle Scholar
• Matsuzaki T, Matsushita T, Takayama K, et al. Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice. Ann Rheum Dis. 2014;73(7):1397–1404.
   PubMed Web of Science ®Google Scholar
• Garimella TS, Ross DD, Bauer KS. Liquid chromatography method for the quantitation of the breast cancer resistance protein ABCG2 inhibitor fumitremorgin C and its chemical analogues in mouse plasma and tissues. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;807(2):203–208.
   PubMed Web of Science ®Google Scholar
• Yuan Y, Chen K, Chen X, et al. Fumitremorgin C attenuates osteoclast formation and function via suppressing RANKL-induced signaling pathways. Front Pharmacol. 2020;11:238.
   PubMed Web of Science ®Google Scholar
• Li H, Chen J, Li B, et al. The protective effects of dulaglutide against advanced glycation end products (AGEs)-induced degradation of type II collagen and aggrecan in human SW1353 chondrocytes. Chem Biol Interact. 2020;322:108968.
   PubMed Web of Science ®Google Scholar
• Guilak F, Nims RJ, Dicks A, et al. Osteoarthritis as a disease of the cartilage pericellular matrix. Matrix Biol. 2018;71-72:40–50.
   PubMed Web of Science ®Google Scholar
• Rabindran SK, He H, Singh M, et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. 1998;58:5850–5858.
   PubMed Web of Science ®Google Scholar
• Rabindran SK, Ross DD, Doyle LA, et al. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 2000;60:47–50.
   PubMed Web of Science ®Google Scholar
• Spector TD, Hart DJ, Nandra D, et al. Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease. Arthritis Rheum. 1997;40:723–727.
   PubMed Web of Science ®Google Scholar
• Livshits G, Zhai G, Hart DJ, et al. Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: the chingford study. Arthritis Rheum. 2009;60:2037–2045.
   PubMed Web of Science ®Google Scholar
• Franceschi C, Bonafe M, Valensin S, et al. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci. 2000;908:244–254.
   PubMed Web of Science ®Google Scholar
• Rahmati M, Nalesso G, Mobasheri A, et al. Aging and osteoarthritis: central role of the extracellular matrix. Ageing Res Rev. 2017;40:20–30.
   PubMed Web of Science ®Google Scholar
• Rigoglou S, Papavassiliou AG. The NF-kappaB signalling pathway in osteoarthritis. Int J Biochem Cell Biol. 2013;45:2580–2584.
   PubMed Web of Science ®Google Scholar
• Rasheed Z, Akhtar N, Haqqi TM. Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor-kappaB in human osteoarthritis chondrocytes. Rheumatology (Oxford). 2011;50:838–851.
   PubMed Web of Science ®Google Scholar
• Loeser RF. Age-related changes in the musculoskeletal system and the development of osteoarthritis. Clin Geriatr Med. 2010;26:371–386.
   PubMed Web of Science ®Google Scholar
• Vila S. Inflammation in osteoarthritis. P R Health Sci J. 2017;36:123–129.
   PubMed Web of Science ®Google Scholar
• Almeida M, Porter RM. Sirtuins and FoxOs in osteoporosis and osteoarthritis. Bone. 2019;121:284–292.
   PubMed Web of Science ®Google Scholar
• Mercurio F, Manning AM. Multiple signals converging on NF-kappaB. Curr Opin Cell Biol. 1999;11:226–232.
   PubMed Web of Science ®Google Scholar
• Zhang W, Robertson WB, Zhao J, et al. Emerging trend in the pharmacotherapy of osteoarthritis. Front Endocrinol (Lausanne). 2019;10:431.
   PubMed Web of Science ®Google Scholar
• Ruangsuriya J, Budprom P, Viriyakhasem N, et al. Suppression of cartilage degradation by zingerone involving the p38 and JNK MAPK signaling pathway. Planta Med. 2017;83:268–276.
   PubMed Web of Science ®Google Scholar