Circular RNA HIPK3 aggravates sepsis-induced acute kidney injury via modulating the microRNA-338/forkhead box A1 axis

References

• Kotecha A, Vallabhajosyula S, Coville HH, et al. Cardiorenal syndrome in sepsis: a narrative review. J Crit Care. 2018;43:122–127.
   PubMed Web of Science ®Google Scholar
• Uchino S, Kellum JA, Bellomo R, et al. Ending supportive therapy for the kidney, acute renal failure in critically Ill patients: a multinational, multicenter study. JAMA. 2005;294(7):813–818.
   PubMed Web of Science ®Google Scholar
• Liu V, Escobar GJ, Greene JD, et al. Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA. 2014;312(1):90–92.
   PubMed Web of Science ®Google Scholar
• Slade E, Tamber PS, Vincent JL. The surviving sepsis campaign: raising awareness to reduce mortality. Crit Care. 2003;7(1):1–2.
   PubMed Web of Science ®Google Scholar
• Shum HP, Kong HH, Chan KC, et al. Septic acute kidney injury in critically ill patients - a single-center study on its incidence, clinical characteristics, and outcome predictors. Ren Fail. 2016;38(5):706–716.
   PubMed Web of Science ®Google Scholar
• Kang K, Gao Y, Wang SC, et al. Dexmedetomidine protects against lipopolysaccharide-induced sepsis-associated acute kidney injury via an α7 nAChR-dependent pathway. Biomed Pharmacother. 2018;106:210–216.
   PubMed Web of Science ®Google Scholar
• Xu C, Chang A, Hack BK, et al. TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis. Kidney Int. 2014;85(1):72–81.
   PubMed Web of Science ®Google Scholar
• Umbro I, Gentile G, Tinti F, et al. Recent advances in pathophysiology and biomarkers of sepsis-induced acute kidney injury. J Infect. 2016;72(2):131–142.
   PubMed Web of Science ®Google Scholar
• Xiong H, Wang H, Yu Q. Circular RNA circ_0003420 mediates inflammation in sepsis-induced liver damage by downregulating neuronal PAS domain protein 4. Immunopharmacol Immunotoxicol. 2021;43(3):271–282.
   PubMed Web of Science ®Google Scholar
• Hong X, Li S, Wang J, et al. Circular RNA circFADS2 is overexpressed in sepsis and suppresses LPS-induced lung cell apoptosis by inhibiting the maturation of miR-15a-5p. BMC Immunol. 2021;22(1):29.
   PubMed Web of Science ®Google Scholar
• Shi X, Ma W, Li Y, et al. CircPRKCI relieves lipopolysaccharide-induced HK2 cell injury by upregulating the expression of miR-545 target gene ZEB2. Biofactors. 2020;46(3):475–486.
   PubMed Web of Science ®Google Scholar
• Xu L, Cao H, Xu P, et al. Circ_0114427 promotes LPS-induced septic acute kidney injury by modulating miR-495-3p/TRAF6 through the NF-κB pathway. Autoimmunity. 2021;1–13. DOI:10.1080/08916934.2021.1995861.
   Web of Science ®Google Scholar
• Fan S, Hu K, Zhang D, et al. Interference of circRNA HIPK3 alleviates cardiac dysfunction in lipopolysaccharide-induced mice models and apoptosis in H9C2 cardiomyocytes. Ann Transl Med. 2020;8(18):1147.
   PubMed Web of Science ®Google Scholar
• Li H, Zhang X, Wang P, et al. Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury. Diabetol Metab Syndr. 2021;13(1):7.
   PubMed Web of Science ®Google Scholar
• Yao Y, Li X, Cheng L, et al. Circular RNA FAT atypical cadherin 1 (circFAT1)/microRNA-525-5p/spindle and kinetochore-associated complex subunit 1 (SKA1) axis regulates oxaliplatin resistance in breast cancer by activating the notch and Wnt signaling pathway. Bioengineered. 2021;12(1):4032–4043.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402–408.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Zhang Y, Wang S, et al. SP1-induced lncRNA ZFPM2 antisense RNA 1 (ZFPM2-AS1) aggravates glioma progression via the miR-515-5p/Superoxide dismutase 2 (SOD2) axis. Bioengineered. 2021;12(1):2299–2310.
   PubMed Web of Science ®Google Scholar
• Zan L, Chen Q, Zhang L, et al. Epigallocatechin gallate (EGCG) suppresses growth and tumorigenicity in breast cancer cells by downregulation of miR-25. Bioengineered. 2019;10(1):374–382.
   PubMed Web of Science ®Google Scholar
• Fouad AA, Abdel-Aziz AM, Hamouda AAH. Diacerein downregulates NLRP3/Caspase-1/IL-1β and IL-6/STAT3 pathways of inflammation and apoptosis in a rat model of cadmium testicular toxicity. Biol Trace Elem Res. 2020;195(2):499–505.
   PubMed Web of Science ®Google Scholar
• Ye T, Zhang N, and Wu W, et al. SNHG14 promotes the tumorigenesis and metastasis of colorectal cancer through miR-32-5p/SKIL axis. In Vitro Cell Dev Biol Anim . 2019;55:812–820.
   PubMed Web of Science ®Google Scholar
• Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign guidelines committee including the pediatric, surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2):580–637. R. Moreno, S.
   PubMed Web of Science ®Google Scholar
• Andrade-Oliveira V, Foresto-Neto O, Watanabe IKM, et al. Inflammation in renal diseases: new and old players. Front Pharmacol. 2019;10:1192.
   PubMed Web of Science ®Google Scholar
• Sugama K, Suzuki K, Yoshitani K, et al. Changes of thioredoxin, oxidative stress markers, inflammation and muscle/renal damage following intensive endurance exercise. Exerc Immunol Rev. 2015;21:130–142.
   PubMed Web of Science ®Google Scholar
• Han D, Fang R, Shi R, et al. LncRNA NKILA knockdown promotes cell viability and represses cell apoptosis, autophagy and inflammation in lipopolysaccharide-induced sepsis model by regulating miR-140-5p/CLDN2 axis. Biochem Biophys Res Commun. 2021;559:8–14.
   PubMed Web of Science ®Google Scholar
• Sureshbabu A, Ryter SW, Choi ME. Oxidative stress and autophagy: crucial modulators of kidney injury. Redox Biol. 2015;4:208–214.
   PubMed Web of Science ®Google Scholar
• Poggi C, Dani C. Sepsis and oxidative stress in the newborn: from pathogenesis to novel therapeutic targets. Oxid Med Cell Longev. 2018;2018:9390140.
   PubMed Web of Science ®Google Scholar
• Lee KH, Tseng WC, and Yang CY, et al. The anti-inflammatory, anti-oxidative, and anti-apoptotic benefits of stem cells in acute ischemic kidney injury. Int J Mol Sci. 2019;2019;20(14):3529.
   Web of Science ®Google Scholar
• Xu HP, Ma XY, Yang C. Circular RNA TLK1 promotes sepsis-associated acute kidney injury by regulating inflammation and oxidative stress through miR-106a-5p/HMGB1 axis. Front Mol Biosci. 2021;8:660269.
   PubMed Web of Science ®Google Scholar
• Wei W, Yao Y, Bi H, et al. Circular RNA circ_0068,888 protects against lipopolysaccharide-induced HK-2 cell injury via sponging microRNA-21-5p. Biochem Biophys Res Commun. 2021;540:1–7.
   PubMed Web of Science ®Google Scholar
• Tan M, Bei R. Circ_0091702 serves as a sponge of miR-545-3p to attenuate sepsis-related acute kidney injury by upregulating THBS2. J Mol Histol. 2021;52(4):717–728.
   PubMed Web of Science ®Google Scholar
• Lai J, Xin J, Fu C, et al. CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p. Cancer Cell Int. 2020;20(1):248.
   PubMed Web of Science ®Google Scholar
• Yu H, Chen Y, Jiang P. Circular RNA HIPK3 exerts oncogenic properties through suppression of miR-124 in lung cancer. Biochem Biophys Res Commun. 2018;506(3):455–462.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhao R, Liu W, et al. Exosomal circHIPK3 released from hypoxia-pretreated cardiomyocytes regulates oxidative damage in cardiac microvascular endothelial cells via the miR-29a/IGF-1 pathway. Oxid Med Cell Longev. 2019;2019:7954657.
   PubMed Web of Science ®Google Scholar
• Shan K, Liu C, Liu BH, et al. Circular noncoding RNA HIPK3 mediates retinal vascular dysfunction in diabetes mellitus. Circulation. 2017;136(17):1629–1642.
   PubMed Web of Science ®Google Scholar
• Yu L, Liu Y. circRNA_0016624 could sponge miR-98 to regulate BMP2 expression in postmenopausal osteoporosis. Biochem Biophys Res Commun. 2019;516(2):546–550.
   PubMed Web of Science ®Google Scholar
• Liu G, Wan Q, Li J, et al. Circ_0038467 regulates lipopolysaccharide-induced inflammatory injury in human bronchial epithelial cells through sponging miR-338-3p. Thorac Cancer. 2020;11(5):1297–1308.
   PubMed Web of Science ®Google Scholar
• Jiang L, Liu XQ, Ma Q, et al. hsa-miR-500a-3P alleviates kidney injury by targeting MLKL-mediated necroptosis in renal epithelial cells. Faseb J. 2019;33(3):3523–3535.
   PubMed Web of Science ®Google Scholar
• Mu X, Wang H, Li H. Silencing of long noncoding RNA H19 alleviates pulmonary injury, inflammation, and fibrosis of acute respiratory distress syndrome through regulating the microRNA-423-5p/FOXA1 axis. Exp Lung Res. 2021;47(4):183–197.
   PubMed Web of Science ®Google Scholar
• Zhang J, Ma D, Kang H, et al. Long noncoding RNA LINC01287 promotes proliferation and inhibits apoptosis of lung adenocarcinoma cells via the miR-3529-5p/RNASEH2A axis under the competitive endogenous RNA pattern. Environ Toxicol. 2021;36(10):2093–2104.
   PubMed Web of Science ®Google Scholar
• Gou L, Zou H, Li B. Long noncoding RNA MALAT1 knockdown inhibits progression of anaplastic thyroid carcinoma by regulating miR-200a-3p/FOXA1. Cancer Biol Ther. 2019;20(11):1355–1365.
   PubMed Web of Science ®Google Scholar
• Lu S, Wu H, Xu J, et al. SIKIAT1/miR-96/FOXA1 axis regulates sepsis-induced kidney injury through induction of apoptosis. Inflamm Res. 2020;69(7):645–656.
   PubMed Web of Science ®Google Scholar