Long non-coding RNA TRPM2 antisense RNA as a potential therapeutic target promotes tumorigenesis and metastasis in esophageal cancer

References

• Watanabe M, Otake R, Kozuki R, et al. Recent progress in multidisciplinary treatment for patients with esophageal cancer. Surg Today. 2020;50(1):12–20.
   PubMed Web of Science ®Google Scholar
• Huang FL, Yu SJ. Esophageal cancer: risk factors, genetic association, and treatment. Asian J Surg. 2018;41(3):210–215.
   PubMed Web of Science ®Google Scholar
• Pennathur A, Gibson MK, Jobe BA, et al. Oesophageal carcinoma. Lancet. 2013;381(9864):400–412.
   PubMed Web of Science ®Google Scholar
• Tan KL, Chia WC, How CW, et al. Benchtop isolation and characterisation of small extracellular vesicles from human mesenchymal stem cells. Mol Biotechnol. 2021;63(9):780–791.
   PubMed Web of Science ®Google Scholar
• Kalluri R, LeBleu VS. The biology, function, and biomedical applications of exosomes. Science. 2020;367(6478):eaau6977.
   PubMed Web of Science ®Google Scholar
• How CW, Ong YS, and Low SS, et al. How far have we explored fungi to fight cancer? Semin Cancer Biol. 2021;S1044-579X(21)00059–6. doi:10.1016/j.semcancer.2021.03.009.
   PubMed Web of Science ®Google Scholar
• Nouri Rouzbahani F, Shirkhoda M, Memari F, et al. Immunotherapy a new hope for cancer treatment: a review. Pak J Biol Sci. 2018;21(3):135–150.
   PubMedGoogle Scholar
• He S, Xu J, Liu X, et al. Advances and challenges in the treatment of esophageal cancer. Acta Pharm Sin B. 2021;11(11):3379–3392.
   PubMed Web of Science ®Google Scholar
• Zhang W, Chen Q, Lei C. lncRNA MIAT promotes cell invasion and migration in esophageal cancer. Exp Ther Med. 2020;19(5):3267–3274.
   PubMed Web of Science ®Google Scholar
• Jiang R, Zhang H, Zhou J, et al. Inhibition of long non-coding RNA XIST upregulates microRNA-149-3p to repress ovarian cancer cell progression. Cell Death Dis. 2021;12(2):145–156.
   PubMed Web of Science ®Google Scholar
• Kulkarni P, Dasgupta P, Hashimoto Y, et al. A lncRNA TCL6-miR-155 interaction regulates the Src-Akt-EMT network to mediate kidney cancer progression and metastasis. Cancer Res. 2021;81(6):1500–1512.
   PubMed Web of Science ®Google Scholar
• Shan TD, Tian ZB, Li Q, et al. Long intergenic noncoding RNA 00908 promotes proliferation and inhibits apoptosis of colorectal cancer cells by regulating KLF5 expression. J Cell Physiol. 2021;236(2):889–899.
   PubMed Web of Science ®Google Scholar
• Xu X, Gu J, Ding X, et al. LINC00978 promotes the progression of hepatocellular carcinoma by regulating EZH2-mediated silencing of p21 and E-cadherin expression. Cell Death Dis. 2019;10(10):752–766.
   PubMed Web of Science ®Google Scholar
• Xue W, Zheng Y, Shen Z, et al. Involvement of long non-coding RNAs in the progression of esophageal cancer. Cancer Commun (Lond). 2021;41(5):371–388.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang W, Liu W, et al. Long noncoding RNA VESTAR regulates lymphangiogenesis and lymph node metastasis of esophageal squamous cell carcinoma by enhancing vegfc mRNA stability. Cancer Res. 2021;81(12):3187–3199.
   PubMed Web of Science ®Google Scholar
• Liu J, Liu ZX, Wu QN, et al. Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming. Nat Commun. 2020;11(1):1507–1522.
   PubMed Web of Science ®Google Scholar
• Liang Y, Chen X, Wu Y, et al. LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein. Cell Death Differ. 2018;25(11):1980–1995.
   PubMed Web of Science ®Google Scholar
• Zhang X, Jiang Y, Xie Y, et al. Inhibition of gastric cancer cell apoptosis by long noncoding RNA TRPM2-AS via mitogen-activated protein kinase and activators of transduction-3. J Gastroenterol Hepatol. 2021;36(1):186–195.
   PubMed Web of Science ®Google Scholar
• Bao MH, Lv QL, Szeto V, et al. TRPM2-AS inhibits the growth, migration, and invasion of gliomas through JNK, c-Jun, and RGS4. J Cell Physiol. 2020;235(5):4594–4604.
   PubMed Web of Science ®Google Scholar
• Cui D, Feng Y, Shi K, et al. Long non-coding RNA TRPM2-AS sponges microRNA-138-5p to activate epidermal growth factor receptor and PI3K/AKT signaling in non-small cell lung cancer. Ann Transl Med. 2020;8(20):1313–1329.
   PubMed Web of Science ®Google Scholar
• Ding Y, Tan X, Abasi A, et al. LncRNA TRPM2-AS promotes ovarian cancer progression and cisplatin resistance by sponging miR-138-5p to release SDC3 mRNA. Aging (Albany NY). 2021;13(5):6832–6848.
   PubMedGoogle Scholar
• Huang B, Chang C, Wang BL, et al. ELK1-induced upregulation of lncRNA TRPM2-AS promotes tumor progression in gastric cancer by regulating miR-195/ HMGA1 axis. J Cell Biochem. 2019;120(10):16921–16933.
   PubMed Web of Science ®Google Scholar
• Li A, Yang J, Zhang T, et al. Long noncoding RNA TRPM2-AS promotes the growth, migration, and invasion of retinoblastoma via miR-497/WEE1 axis. Front Pharmacol. 2021;12:592822–592834.
   PubMed Web of Science ®Google Scholar
• Orfanelli U, Jachetti E, Chiacchiera F, et al. Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer. Oncogene. 2015;34(16):2094–2102.
   PubMed Web of Science ®Google Scholar
• Pan L, Li Y, Jin L, et al. TRPM2-AS promotes cancer cell proliferation through control of TAF15. Int J Biochem Cell Biol. 2020;120:105683–105690.
   PubMed Web of Science ®Google Scholar
• Sun J, Zhou F, Xue J, et al. Long non-coding RNA TRPM2-AS regulates microRNA miR-138-5p and PLAU (Plasminogen Activator, Urokinase) to promote the progression of gastric adenocarcinoma. Bioengineered. 2021;12(2):9753–9765.
   PubMed Web of Science ®Google Scholar
• Tian Y, Guan Y, Su Y, et al. TRPM2-AS promotes bladder cancer by targeting miR-22-3p and regulating GINS2 mRNA expression. Onco Targets Ther. 2021;14:1219–1237.
   PubMed Web of Science ®Google Scholar
• Wang N, Wang L, Pan X. Long non-coding RNA TRPM2-AS promotes cell migration and invasion by serving as a ceRNA of miR-138 and inducing SOX4-mediated EMT in laryngeal squamous cell Carcinoma. Cancer Manag Res. 2020;12:7805–7812.
   PubMed Web of Science ®Google Scholar
• Xiao J, Lin L, Luo D, et al. Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance. Oncogenesis. 2020;9(3):29–43.
   PubMed Web of Science ®Google Scholar
• Xu C, Huang Q, Zhang C, et al. Long non-coding RNA TRPM2-AS as a potential biomarker for hepatocellular carcinoma. Ir J Med Sci. 2018;187(3):621–628.
   PubMed Web of Science ®Google Scholar
• Mouraviev V, Lee B, Patel V, et al. Clinical prospects of long noncoding RNAs as novel biomarkers and therapeutic targets in prostate cancer. Prostate Cancer Prostatic Dis. 2016;19(1):14–20.
   PubMed Web of Science ®Google Scholar
• Wu C, Wang Z, Tian X, et al. Long non-coding RNA DDX11-AS1 promotes esophageal carcinoma cell proliferation and migration through regulating the miR-514b-3p/RBX1 axis. Bioengineered. 2021;12(1):3772–3786.
   PubMed Web of Science ®Google Scholar
• Boieri M, Ulvmoen A, Sudworth A, et al. IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo. Oncoimmunology. 2017;6(3):e1274478–e1274490.
   PubMed Web of Science ®Google Scholar
• Franken NA, Rodermond HM, Stap J, et al. Clonogenic assay of cells in vitro. Nat Protoc. 2006;1(5):2315–2319.
   PubMed Web of Science ®Google Scholar
• Fares J, Fares MY, Khachfe HH, et al. Molecular principles of metastasis: a hallmark of cancer revisited. Signal Transduct Target Ther. 2020;5(1):28–44.
   PubMed Web of Science ®Google Scholar
• Mittal V. Epithelial mesenchymal transition in tumor metastasis. Annu Rev Pathol. 2018;13(1):395–412.
   PubMed Web of Science ®Google Scholar
• Luo H, Guo W, Wang F, et al. miR-1291 targets mucin 1 inhibiting cell proliferation and invasion to promote cell apoptosis in esophageal squamous cell carcinoma. Oncol Rep. 2015;34(5):2665–2673.
   PubMed Web of Science ®Google Scholar
• Cui BH, Hong X. miR-6852 serves as a prognostic biomarker in colorectal cancer and inhibits tumor growth and metastasis by targeting TCF7. Exp Ther Med. 2018;16(2):879–885.
   PubMed Web of Science ®Google Scholar
• Zheng S, Zhang X, Wang X, et al. Downregulation of miR-138 predicts poor prognosis in patients with esophageal squamous cell carcinoma. Cancer Biomark. 2017;20(1):49–54.
   PubMed Web of Science ®Google Scholar
• Liu Y, Wu Y, Liu S, et al. Long non-coding RNA TRIM52-AS1 promotes growth and metastasis via miR-218-5p/ROBO1 in hepatocellular Carcinoma. Cancer Manag Res. 2021;13:547–558.
   PubMed Web of Science ®Google Scholar
• Li C, Wang F, Wei B, et al. LncRNA AWPPH promotes osteosarcoma progression via activation of Wnt/β-catenin pathway through modulating miR-93-3p/FZD7 axis. Biochem Biophys Res Commun. 2019;514(3):1017–1022.
   PubMed Web of Science ®Google Scholar
• Huang C, Qin Y, Liu H, et al. Downregulation of a novel long noncoding RNA TRPM2-AS promotes apoptosis in non–small cell lung cancer. Tumour Biol. 2017;39(2): 1010428317691191–8. DOI:10.1177/1010428317691191.
   Google Scholar
• Ma L-Y, Xie X-W, Ma L, et al. Downregulated long non-coding RNA TRPM2-AS inhibits cisplatin resistance of non-small cell lung cancer cells via activation of p53- p66shc pathway. Eur Rev Med Pharmacol Sci. 2017;21(11):2626–2634.
   PubMed Web of Science ®Google Scholar
• Guo Y, Sun P, Guo W, et al. LncRNA DDX11 antisense RNA 1 promotes EMT process of esophageal squamous cell carcinoma by sponging miR-30d-5p to regulate SNAI1/ZEB2 expression and Wnt/β-catenin pathway. Bioengineered. 2021;12(2):11425–11440.
   PubMed Web of Science ®Google Scholar
• Li H-Y, Liang J-L, Kuo Y-L, et al. miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer. Breast Cancer Res. 2017;19(1):133–146.
   PubMedGoogle Scholar
• Poudyal D, Herman A, Adelsberger JW, et al. A novel microRNA, HSA-miR-6852 differentially regulated by interleukin-27 induces necrosis in cervical cancer cells by downregulating the foxm1 expression. Sci Rep. 2018;8(1):900–912.
   PubMedGoogle Scholar
• Pandey MK, Sung B, Ahn KS, et al. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway. Blood. 2007;110(10):3517–3525.
   PubMed Web of Science ®Google Scholar
• Chen Y, Zhou Y, Han F, et al. A novel miR-1291-ERRα-CPT1C axis modulates tumor cell proliferation, metabolism and tumorigenesis. Theranostics. 2020;10(16):7193–7210.
   PubMed Web of Science ®Google Scholar
• Wu J, Wang L, Du X, et al. α-solanine enhances the chemosensitivity of esophageal cancer cells by inducing microRNA‑138 expression. Oncol Rep. 2018;39(3):1163–1172.
   PubMed Web of Science ®Google Scholar
• Wang Y, Wu J, Guo W, et al. α-solanine modulates the radiosensitivity of esophageal cancer cells by inducing microRNA 138 expression. Cell Physiol Biochem. 2016;39(3):996–1010.
   PubMedGoogle Scholar