1,202
Views
5
CrossRef citations to date
0
Altmetric
Research Paper

Quercitrin restrains the growth and invasion of lung adenocarcinoma cells by regulating gap junction protein beta 2

, , &
Pages 6126-6135 | Received 09 Dec 2021, Accepted 29 Jan 2022, Published online: 23 Feb 2022

References

  • DeSantis CE, Ma J, Gaudet MM, et al. Breast cancer statistics, 2019. CA Cancer J Clin. 2019;69(6):438–451.
  • Nicot C. RNA-Seq reveal the circular RNAs landscape of lung cancer. Mol Cancer. 2019;18(1):183.
  • Ji W, Zhang L, Zhu H. GATA binding protein 5 (GATA5) induces Rho GTPase activating protein 9 (ARHGAP9) to inhibit the malignant process of lung adenocarcinoma cells. Bioengineered. 2022;13(2):2878–2888.
  • Zhu T, Bao X, Chen M, et al. Mechanisms and Future of Non-Small Cell Lung Cancer Metastasis. Front Oncol. 2020;10:585284.
  • Wang W, Wang H, Wang CM, et al. Treatment with Huisheng oral solution inhibits the development of pulmonary thromboembolism and metastasis in mice with Lewis lung carcinoma. Oncol Lett. 2014;7(1):87–94.
  • Li Y, Huang T, Fu Y, et al. Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway. PLoS One. 2019;14(9):e0215886.
  • Palmer TD, Ashby WJ, Lewis JD, et al. Targeting tumor cell motility to prevent metastasis. Adv Drug Deliv Rev. 2011;63(8):568–581.
  • Fabjan N, Rode J, Kosir IJ, et al. Tartary Buckwheat (Fagopyrum tataricum Gaertn.) as a Source of Dietary Rutin and Quercitrin. J Agric Food Chem. 2003;51(22):6452–6455.
  • Guo H, Yin W, Zou Z, et al. Quercitrin alleviates cartilage extracellular matrix degradation and delays ACLT rat osteoarthritis development: an in vivo and in vitro study. J Adv Res. 2021;28:255–267.
  • Bak MJ, Jeong JH, Kang HS, et al. Stimulation of Activity and Expression of Antioxidant Enzymes by Solvent Fractions and Isolated Compound from Cedrela sinensis Leaves in HepG2 Cells. J Med Food. 2011;14(4):405–412.
  • Gomez-Florit M, Monjo M, Ramis JM. Quercitrin for periodontal regeneration: effects on human gingival fibroblasts and mesenchymal stem cells. Sci Rep. 2015;5(1):16593.
  • Cincin ZB, Unlu M, Kiran B, et al. Apoptotic Effects of Quercitrin on DLD-1 Colon Cancer Cell Line. Pathol Oncol Res. 2015;21(2):333–338.
  • Cincin ZB, Unlu M, Kiran B, et al. Molecular mechanisms of quercitrin-induced apoptosis in non-small cell lung cancer. Arch Med Res. 2014;45(6):445–454.
  • Ezumi K, Yamamoto H, Murata K, et al. Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer. Clin Cancer Res. 2008;14(3):677–684.
  • Inose T, Kato H, Kimura H, et al. Correlation between connexin 26 expression and poor prognosis of esophageal squamous cell carcinoma. Ann Surg Oncol. 2009;16(6):1704–1710.
  • Tang Y, Zhang YJ, Wu ZH. High GJB2 mRNA expression and its prognostic significance in lung adenocarcinoma: a study based on the TCGA database. Medicine (Baltimore). 2020;99(14):e19054.
  • Zeng SG, Lin X, Liu JC, et al. Hypoxiainduced internalization of connexin 26 and connexin 43 in pulmonary epithelial cells is involved in the occurrence of nonsmall cell lung cancer via the P53/MDM2 signaling pathway. Int J Oncol. 2019;55(4):845–859.
  • Yang J, Qin G, Luo M, et al. Reciprocal positive regulation between Cx26 and PI3K/Akt pathway confers acquired gefitinib resistance in NSCLC cells via GJIC-independent induction of EMT. Cell Death Dis. 2015;6(7):e1829.
  • Ito A, Koma Y, Uchino K, et al. Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: significant correlation with poor prognosis. Cancer Lett. 2006;234(2):239–248.
  • Zhang J, Liu D, Deng G, et al. lncRNA prostate cancer-associated transcript 18 upregulates activating transcription factor 7 to prevent metastasis of triple-negative breast cancer via sponging miR-103a-3p. Bioengineered. 2021;12(2):12070–12086.
  • Liu K, Lin J. Delta133p53 decreases the chemosensitivity of carcinoma cell line H1299. Cell Biol Int. 2019;43(8):960–964.
  • Middleton E Jr., Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev. 2000;52(4):673–751.
  • Kim HJ, Park CG, Varghese R, et al. In-vitro antioxidative, antiinflammatory properties of Aurea helianthus leaf extract a Korean traditional medicinal plant. Saudi J Biol Sci. 2017;24(8):1943–1947.
  • Ding M, Zhao J, Bowman L, et al. Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrin. Int J Oncol. 2010;36(1):59–67.
  • Zhi K, Li M, Bai J, et al. Quercitrin treatment protects endothelial progenitor cells from oxidative damage via inducing autophagy through extracellular signal-regulated kinase. Angiogenesis. 2016;19(3):311–324.
  • Li W, Cheng M, Zhang W, et al. New Insights into the Mechanisms of Polyphenol from Plum Fruit Inducing Apoptosis in Human Lung Cancer A549 Cells Via PI3K/AKT/FOXO1 Pathway. Plant Foods Hum Nutr. 2021;76(1):125–132.
  • Jolly MK, Ware KE, Gilja S, et al. EMT and MET: necessary or permissive for metastasis? Mol Oncol. 2017;11(7):755–769.
  • Liu Q, Zhang H, Jiang X, et al. Factors involved in cancer metastasis: a better understanding to “seed and soil” hypothesis. Mol Cancer. 2017;16(1):176.
  • Liu Y, Pandey PR, Sharma S, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019;175(1):77–90.
  • Zhu T, Gao YF, Chen YX, et al. Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer. Oncotarget. 2017;8(13):21281–21289.