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Research Paper

Effects of artesunate on the malignant biological behaviors of non-small cell lung cancer in human and its mechanism

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Pages 6590-6599 | Received 27 Oct 2021, Accepted 10 Feb 2022, Published online: 31 Mar 2022

References

  • Cheng TY, Cramb SM, Baade PD, et al. The international epidemiology of lung cancer: latest trends, disparities, and tumor characteristics. J Thorac Oncol. 2016;11(10):1653–1671.
  • Huang CY, Ju DT, Chang CF, et al. A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer. Biomedicine (Taipei). 2017;7(4):12–23.
  • Sgambato A, Casaluce F, Sacco PC, et al. Anti PD-1 and PDL-1 immunotherapy in the treatment of advanced non-small cell lung cancer (NSCLC): a review on toxicity profile and its management. Curr Drug Saf. 2016;11(1):62–68.
  • Li H, Zhao J, Jia X, et al. miR-21 promotes growth, invasion and migration of lung cancer cells by AKT/P-AKT/cleaved-caspase 3/MMP-2/MMP-9 signaling pathway. Int J Clin Exp Pathol. 2020;13(4):692–700.
  • Chen X, Han K, Chen F, et al. Effects of artesunate on the invasion of lung adenocarcinoma A549 cells and expression of ICAM-1 and MMP-9. Chin J Lung Cancer. 2013;16(11):567–571.
  • Pashkina E, Aktanova A, Mirzaeva I, et al. The effect of Cucurbit[7]uril on the antitumor and immunomodulating properties of oxaliplatin and carboplatin. Int J Mol Sci. 2021;22(14):7337.
  • White NJ, Hien TT, Nosten FH. A brief history of Qinghaosu. Trends Parasitol. 2015;31(12):607–610.
  • Miller LH, Su X. Artemisinin: discovery from the Chinese herbal garden. Cell. 2011;146(6):855–858.
  • Yang X, Zheng Y, Liu L, et al. Progress on the study of the anticancer effects of artesunate. Oncol Lett. 2021;22(5):750.
  • Khanal P. Antimalarial and anticancer properties of artesunate and other artemisinins: current development. Monatsh Chem. 2021;152(4):387–400.
  • Crespo-Ortiz MP, Wei MQ. Antitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drug. BioMed Res Int. 2012;2012:247597.
  • Srikantan S, Gorospe M. HuR function in disease. Front Biosci (Landmark Ed). 2012;17(1):189–205.
  • Wang J, Zhao W, Guo Y, et al. The expression of RNA-binding protein HuR in non-small cell lung cancer correlates with vascular endothelial growth factor-C expression and lymph node metastasis. Oncology. 2009;76(6):420–429.
  • Wang J, Wang B, Bi J, et al. Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer. Med Oncol. 2011;28(S1):577–585.
  • Ran T, Ke S, Song X, et al. WIPI1 promotes osteosarcoma cell proliferation by inhibiting CDKN1A. Gene. 2021;782:145537.
  • Gough W, Hulkower KI, Lynch R, et al. A quantitative, facile, and high-throughput image-based cell migration method is a robust alternative to the scratch assay. J Biomol Screen. 2011;16(2):155–163.
  • Yuan L, Lei L, Yang L, et al. RECK inhibits cervical cancer cell migration and invasion by promoting p53 signaling pathway. J Cell Biochem. 2018;119(4):3058–3066.
  • Hanachi P, Fakhrnezhad FR, Zarringhalami R, et al. Cytotoxicity of Ocimum basilicum and Impatiens walleriana Extracts on AGS and SKOV-3 cancer cell lines by flow cytometry analysis. Int J Cancer Manage. 2021;14(3):e102610.
  • Mo M, Zhou M, Wang L, et al. CCL21/CCR7 enhances the proliferation, migration, and invasion of human bladder cancer T24 cells. PloS One. 2015;10(3):e0119506.
  • Halatsch ME, Debatin KM, Wirtz CR, et al. Artesunate Enhances the Antiproliferative Effect of Temozolomide on U87MG and A172 Glioblastoma Cell Lines. Anticancer Agents Med Chem. 2014;14(2):313–318.
  • Xu H, Brown GL, Schow SR, et al. Combination cancer therapy with a GST-activated anticancer compound and another anticancer therapy. 2004;2004045593–A3.
  • Alvarado-Luna G, Morales-Espinosa D. Treatment for small cell lung cancer, where are we now?-a review. Transl Lung Cancer Res. 2016;5(1):26–38.
  • Rizvi NA, Hellmann MD, Brahmer JR, et al. Nivolumab in combination with platinum-based doublet chemotherapy for first-line treatment of advanced non-small-cell lung cancer. J Clin Oncol. 2016;34(25):2969–2979.
  • Lu JJ, Huang MQ, Chen XP, et al. Progress in anti-neoplastic effects and mechanisms of dihydroartemisinin]. Chin J Pharmacol Toxicol. 2012;26(3):397–401.
  • Tan L, Chen H, Wei N, et al. Anti-inflammatory and immunomodulatory mechanisms of artemisinin on contact hypersensitivity. Int Immunopharmacol. 2012;12(1):144–150.
  • Fröhlich T, Reiter C, Ibrahim MM, et al. Synthesis of novel hybrids of quinazoline and artemisinin with high activities against Plasmodium falciparum, human Cytomegalovirus, and Leukemia Cells. ACS Omega. 2017;2(6):2422–2431.
  • He R, Zhou H. Progress in research on the anti-tumor effect of artesunate. Chin J Integr Med. 2008;14(4):312–316.
  • Greenshields AL, Fernando W, Hoskin DW. The anti-malarial drug artesunate causes cell cycle arrest and apoptosis of triple-negative MDA-MB-468 and HER2-enriched SK-BR-3 breast cancer cells. Exp Mol Pathol. 2019;107:10–22.
  • Zhou C, Pan W, Wang XP, et al. Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells. J Cell Physiol. 2012;227(12):3778–3786.
  • Wang Z, Wang Q, He T, et al. The combination of artesunate and carboplatin exerts a synergistic anti-tumour effect on non-small cell lung cancer. Clin Exp Pharmacol Physiol. 2020;47(6):1083–1091.
  • Wang CM, Li HX, Zhang XF. Role of Fas, FasL and Caspase-3 in artesunate-induced apoptosis of human embryonic lung fibroblasts. J Clin Rehab Tissue Eng Res. 2011;15(20):3785–3788.
  • Bachmeier B, Fichtner I, Killian PH, et al. Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells. PloS One. 2011;6(5):e20550.
  • Rasheed SA, Efferth T, Asangani IA, et al. First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases. Int J Cancer. 2010;127(6):1475–1485.
  • Safranek J, Pesta M, Holubec L, et al. Expression of MMP-7, MMP-9, TIMP-1 and TIMP-2 mRNA in lung tissue of patients with non-small cell lung cancer (NSCLC) and benign pulmonary disease. Anticancer Res. 2009;29(7):2513–2517.
  • Kopczyńska E, Dancewicz M, Kowalewski J, et al. The serum concentration of metalloproteinase 9 and 2 in non-small cell lung cancer patients]. Pol Merkur Lekarski. 2007;22(132):539–541.
  • Wang J, Guo Y, Chu H, et al. Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis. Int J Mol Sci. 2013;14(5):10015–10041.
  • Abdelmohsen K, Gorospe M. Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip Rev RNA. 2010;1(2):214–229.