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Bioengineered Volume 13, 2022 - Issue 5
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Research Paper

IFC-305 attenuates renal ischemia-reperfusion injury by promoting the production of hydrogen sulfide (H2S) via suppressing the promoter methylation of cystathionine γ-lyase (CSE)

Jie JiangNephrology Department, Dongguan People’s Hospital Affiliated to Southern Medical University, Dongguan, ChinaView further author information
,
Chuling WenNephrology Department, Dongguan People’s Hospital Affiliated to Southern Medical University, Dongguan, ChinaView further author information
,
Yi LiNephrology Department, Dongguan People’s Hospital Affiliated to Southern Medical University, Dongguan, ChinaView further author information
,
Guohui LiuNephrology Department, Dongguan People’s Hospital Affiliated to Southern Medical University, Dongguan, ChinaView further author information
,
Zijun ChenNephrology Department, Dongguan People’s Hospital Affiliated to Southern Medical University, Dongguan, ChinaView further author information
&
Dongwen ZhengNephrology Department, Dongguan People’s Hospital Affiliated to Southern Medical University, Dongguan, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4532-8301View further author information
ORCID Icon
Pages 12045-12054 | Received 16 Jan 2022, Accepted 27 Mar 2022, Published online: 13 May 2022

References

  • Bonventre JV. Mechanisms of ischemic acute renal failure. Kidney Int. 1993;43:1160–1178.
  • Qi H, Zhang J, Shang Y, et al. Argon inhibits reactive oxygen species oxidative stress via the miR-21-mediated PDCD4/PTEN pathway to prevent myocardial ischemia/reperfusion injury. Bioengineered. 2021;12(1):5529–5539.
  • Dobashi K, Ghosh B, Orak JK, et al. Kidney ischemia-reperfusion: modulation of antioxidant defenses. Mol Cell Biochem. 2000;205:1–11.
  • Kim J, Park JW, Park KM. Increased superoxide formation induced by irradiation preconditioning triggers kidney resistance to ischemia-reperfusion injury in mice. Am J Physiol Renal Physiol. 2009;296:F1202–1211.
  • Chatterjee PK. Novel pharmacological approaches to the treatment of renal ischemia-reperfusion injury: a comprehensive review. Naunyn Schmiedebergs Arch Pharmacol. 2007;376(1–2):1–43.
  • Zeng O, Li F, Li Y, et al. Effect of novel gasotransmitter hydrogen sulfide on renal fibrosis and connexins expression in diabetic rats. Bioengineered. 2016;7(5):314–320.
  • Yang G, Wu L, Jiang B, et al. H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science. 2008;322:587–590.
  • Hu LF, Lu M, Hon Wong PT, et al. Hydrogen sulfide: neurophysiology and neuropathology. Antioxid Redox Signal. 2011;15:405–419.
  • Rodriguez-Aguilera JR, Guerrero-Hernandez C, Perez-Molina R, et al. Epigenetic effects of an adenosine derivative in a Wistar rat model of liver cirrhosis. J Cell Biochem. 2018;119:401–413.
  • Li S, Qiu B, Lu H, et al. Hyperhomocysteinemia accelerates acute kidney injury to chronic kidney disease progression by downregulating heme oxygenase-1 expression. Antioxid Redox Signal. 2019;30:1635–1650.
  • Wang P, Isaak CK, Siow YL, et al. Downregulation of cystathionine beta-synthase and cystathionine gamma-lyase expression stimulates inflammation in kidney ischemia-reperfusion injury. Physiol Rep. 2014;2(12):e12251.
  • Li JJ, Li Q, Du HP, et al. Homocysteine triggers inflammatory responses in macrophages through inhibiting CSE-H2S signaling via DNA hypermethylation of CSE promoter. Int J Mol Sci. 2015;16:12560–12577.
  • Pérez-Carreón JI, Martínez-Pérez L, Loredo ML, et al. An adenosine derivative compound, IFC305, reverses fibrosis and alters gene expression in a pre-established CCl(4)-induced rat cirrhosis. Int J Biochem Cell Biol. 2010;42(2):287–296.
  • Aranda P, Segura J, Ruilope LM, et al. Long-term renoprotective effects of standard versus high doses of telmisartan in hypertensive nondiabetic nephropathies. Am J Kidney Dis. 2005;46:1074–1079.
  • Bearden SE, Beard RS Jr., Pfau JC. Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress. Am J Physiol Heart Circ Physiol. 2010;299:H1568–1576.
  • Prudova A, Bauman Z, Braun A, et al. S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity. Proc Natl Acad Sci U S A. 2006;103:6489–6494.
  • Eto K, Kimura H. A novel enhancing mechanism for hydrogen sulfide-producing activity of cystathionine beta-synthase. J Biol Chem. 2002;277:42680–42685.
  • Wang R. The gasotransmitter role of hydrogen sulfide. Antioxid Redox Signal. 2003;5:493–501.
  • Kamoun P. Endogenous production of hydrogen sulfide in mammals. Amino Acids. 2004;26:243–254.
  • Elrod JW, Calvert JW, Morrison J, et al. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci U S A. 2007;104:15560–15565.
  • Dayal S, Wilson KM, Leo L, et al. Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia. Blood. 2006;108:2237–2243.
  • Kimura Y, Kimura H. Hydrogen sulfide protects neurons from oxidative stress. FASEB J. 2004;18:1165–1167.
  • Kimura Y, Dargusch R, Schubert D, et al. Hydrogen sulfide protects HT22 neuronal cells from oxidative stress. Antioxid Redox Signal. 2006;8:661–670.
  • Yang G, Cao K, Wu L, et al. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. J Biol Chem. 2004;279:49199–49205.
  • Ploeg RJ, van Bockel JH, Langendijk PT, et al. Effect of preservation solution on results of cadaveric kidney transplantation. The European Multicentre Study Group. Lancet. 1992;340:129–137.
  • Sung FL, Zhu TY, Au-Yeung KK, et al. Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-kappaB. Kidney Int. 2002;62:1160–1170.
  • Xia M, Chen L, Muh RW, et al. Production and actions of hydrogen sulfide, a novel gaseous bioactive substance, in the kidneys. J Pharmacol Exp Ther. 2009;329:1056–1106.

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