1,838
Views
1
CrossRef citations to date
0
Altmetric
Research Paper

MicroRNA-146 attenuates lipopolysaccharide induced ovarian dysfunction by inhibiting the TLR4/NF- κB signaling pathway

, , , , , & show all
Pages 11611-11623 | Received 27 Jan 2022, Accepted 22 Apr 2022, Published online: 08 May 2022

References

  • Prosper I, Abdeljabar EA, Ujalla S, et al. Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature. J Med Case Rep. 2020;14(1):108.
  • Giri R, Vincent AJ. Prevalence and Risk Factors of Premature Ovarian Insufficiency/ Early Menopause. Semin Reprod Med. 2020;38(4–05):237–246.
  • Tatang C, Arredondo-Bisonó T, Bergamasco A, et al. Human PapillomavirusVaccination and Premature Ovarian Failure: a Disproportionality Analysis Using the Vaccine Adverse Event Reporting System. Drugs Real World Outcomes. 2022;9(1):79–90.
  • Deng T, Jing H, Yao Q, et al. Human Umbilical Cord Mesenchymal Stem Cells Improve Ovarian Function in Chemotherapy-Induced Premature Ovarian Failure Mice Through Inhibiting Apoptosis and Inflammation via a Paracrine Mechanism. Reprod Sci. 2021;28(6):1718–1732.
  • Nahand JS, Karimzadeh MR, Nezamnia M, et al. The role of miR-146a in viral infection. IUBMB Life. 2020;72(3):343–360.
  • LB Z, XY G, Jp G, et al. Notoginsenoside R1 upregulates miR-221-3p expression to alleviate ox-LDL-induced apoptosis, inflammation, and oxidative stress by inhibiting the TLR4/NF-kB pathway in HUVECs. Journal of Medical and Biological Research. 2020;53(6): e9346
  • Zhang J, Xu Y, Liu H, et al. MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis. Reprod Biol Endocrinol. 2019;17(1):9
  • Wang Q, Li D, Han Y, et al. MicroRNA-146 protects A549 and H1975 cells from LPS-induced apoptosis and inflammation injury. J Biosci. 2017;42(4):637–645.
  • Fumie M. Lipopolysaccharide-induced mechanisms of ovarian dysfunction in cows with uterine inflammatory diseases. J Reprod Dev. 2020;66(4):311–317.
  • Wang X, Li C, Wang Y, et al. UFL1 Alleviates LPS-Induced Apoptosis by Regulating the NF-kappaB Signaling Pathway in Bovine Ovarian Granulosa Cells. Biomolecules. 2020;10(2):260.
  • Xie Y, Zhang K, Zhang K, et al. Toll-like receptors and high mobility group box 1 in granulosa cells during bovine follicle maturation. J Cell Physiol. 2020;235(4):3447–3462.
  • Yang M, Wang X, Wang L, et al. IL-1alpha Up-Regulates IL-6 Expression in Bovine Granulosa Cells via MAPKs and NF-kappaB Signaling Pathways. Cell Physiol Biochem. 2017;41(1):265–273.
  • Li R, Ma C, Xiong Y, et al. An Antagonistic Peptide of Gpr1 Ameliorates LPS- Induced Depression through the Hypothalamic-Pituitary-Ovarian. Axis.Biomolecules. 2021;11(6):857.
  • Bidne KL, Kvidera SS, Ross JW, et al. Impact of repeated lipopolysaccharide administration on ovarian signaling during the follicular phase of the estrous cycle in post-pubertal pigs. J Anim Sci. 2018;96(9):3622–3634.
  • Cakiroglu Y, Saltik A, Yuceturk A, et al. Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency. Aging (Albany NY). 2020;12(11):10211–10222.
  • Te Liu JL, Chen C, Chen C, et al. MicroRNA-146b-5p overexpression attenuates premature ovarian failure in mice by inhibiting the Dab2ip/Ask1/p38-Mapk pathway and γH2A.X phosphorylation [J]. Cell Prolif. 2021;54(1):e12954.
  • Takahashi A, Yousif A, Hong L, et al. Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell. J Mol Med (Berl). 2021;99(5):637–650.
  • Nahideh NY, Reza R, B AM, et al. Menstrual blood CD146+ mesenchymal stem cells reduced fibrosis rate in the rat model of premature ovarian failure. Cell Biochem Funct. 2021;39(8):998–1008.
  • Shahin A, Mahdi M, Mohammad P, et al. Effectiveness of Stem Cell Therapy in the Treatment of Ovarian Disorders and Female Infertility: a Systematic Review. Curr Stem Cell Res Ther. 2020;15(2):173–186.
  • Na J, Kim GJ. Recent trends in stem cell therapy for premature ovarian insufficiency and its therapeutic potential: a review. J Ovarian Res. 2020;13(1):74.
  • Zhang H, Luo Q, Lu X, et al. Effects of hPMSCs on granulosa cell apoptosis and AMH expression and their role in the restoration of ovary function in premature ovarian failure mice. Stem Cell Res Ther. 2018;9(1):20.
  • Zhi Z, Wei X, Jingming X, et al. Bone marrow-derived mesenchymal stem cells (BM-MSCs) inhibit apoptosis of spinal cord cells in a kaolin-induced syringomyelia- associated scoliosis rabbit model. Int J Clin Exp Pathol. 2018 Apr 1;11(4):1890–1899.
  • Gao N, Dong L. MicroRNA-146 regulates the inflammatory cytokines expression in vascular endothelial cells during sepsis. Pharmazie. 2017;72(11):700–704.
  • Zhou Y, Zhou J, Xu X. Xu X, et al.Matrigel/Umbilical Cord-Derived Mesenchymal Stem Cells Promote Granulosa Cell Proliferation and Ovarian Vascularization in a Mouse Model of Premature Ovarian Failure. Stem Cells Dev. 2021;30(15):782–796.
  • Daojuan W, Yajing W, Yaling Z, et al. Exposure to hyperandrogen drives ovarian dysfunction and fibrosis by activating the NLRP3 inflammasome in mice. Sci Total Environ. 2020;745:141049.
  • Karunakaran D, Nguyen MA, Geoffrion M, et al. RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-kappaB Activation and Atherogenesis in Mice. Circulation. 2021;143(2):163–177.
  • Gao N, Dong L. MicroRNA-146 regulates the inflammatory cytokines expression in vascular endothelial cells during sepsis. Pharmazie. 2017;72(11):700–704.
  • Zhang C, Ma K, Yang Y, et al. Glaucocalyxin A suppresses inflammatory responses and induces apoptosis in TNF-a-induced human rheumatoid arthritis via modulation of the STAT3 pathway. Chem Biol Interact. 2021;341:109451.
  • Li H, Zhao W, Wang L, et al. Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1alpha pathway in autoimmune POF mice. Cell Biol Int. 2019;43(8):899–909.
  • Skliutė G, Baušytė R, Borutinskaitė V, et al. Menstrual Blood-Derived Endometrial Stem Cells’ Impact for the Treatment Perspective of Female Infertility. Int J Mol Sci. 2021;22(13):6774.
  • Ding C, Zhu L, Shen H, et al.$3$2 Exosomal miRNA-17-5p derived from human umbilical cord mesenchymal stem cells improves ovarian function in premature ovarian insufficiency by regulating SIRT7[J]. Stem Cells. 2020;38(9):1137–1148.
  • Yusuf C, Salih K, Ali O, et al. Prediction of Lipoprotein- Associated Phospholipase A2 and Inflammatory Markers in Subclinical Atherosclerosis in Premature Ovarian Failure Patients. [J] Acta Cardiol Sin. 2021;37(1): 30–37
  • Roganović J. Downregulation of microRNA-146a in diabetes, obesity and hypertension may contribute to severe COVID-19. Med Hypotheses. 2021;146:110448.
  • Fu X, He Y, Wang X, et al. Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis. Stem Cell Res Ther. 2017;8(1):187.
  • Sun B, Ma Y, Wang F, et al. miR-644-5p carried by bone mesenchymal stem cell-derived exosomes targets regulation of p53 to inhibit ovarian granulosa cell apoptosis. Stem Cell Res Ther. 2019;10(1):360.
  • Xiao GY, Cheng CC, Chiang Y-S. Chiang YS, et al.Exosomal miR-10a derived from amniotic fluid stem cells preserves ovarian follicles after chemotherapy. Sci Rep. 2016;6(1):23120.
  • Ding C, Zhu L, Shen H, et al. Exosomal miRNA-17-5p derived from human umbilical cord mesenchymal stem cells improves ovarian function in premature ovarian insufficiency by regulating SIRT7. Stem Cells. 2020;38(9):1137–1148.
  • Abraham Gnanadass S, Divakar Prabhu Y, Valsala Gopalakrishnan A. Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update. Arch Gynecol Obstet. 2021;303(3):631–643.
  • Pavel DC, Brandon MM, Sonia AL, et al. TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. 2019;134(9):727–740.
  • Ma H, Dong Y, Sun K, et al. Protective effect of MiR-146 on renal injury following cardiopulmonary bypass in rats through mediating NF-kappaB signaling pathway. Bioengineered. 2022;13(1):593–602.
  • Feng J, Zhu Y, Chen L, et al. Clinical Significance of microRNA-146a in Patients with Ulcerative Colitis. Ann Clin Lab Sci. 2020;50(4):463–467.
  • Zheng Y, Ma L, Liu N, et al. Autophagy and Apoptosis of Porcine Ovarian Granulosa Cells During Follicular Development. Animals (Basel). 2019 Dec 10;9(12):1111.
  • Yin N, Wu C, Qiu J, et al. Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway- regulated autophagy and upregulating the circulating of CD8(+)CD28(-) T cells. Stem Cell Res Ther. 2020;11(1):49.
  • Yang H, Xie Y, Yang D, et al. Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma. Oncotarget. 2017;8(15):25310–25322.
  • Gong Y, Luo S, Fan P, et al. Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome. Reprod Biol Endocrinol. 2020;18(1):121.
  • Ferranti EM, Aloqaily BH, Gifford CA, et al. Effects of lipopolysaccharide on beta-catenin, aromatase, and estrogen production in bovine granulosa cell in vivo and in vitro. Domest Anim Endocrinol. 2022;78:106652.
  • Karunakaran D, Nguyen MA, Geoffrion M, et al. RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-kappaB Activation and Atherogenesis in Mice. Circulation. 2021;143(2):163–177.
  • Zhang W, Shao M, He X, et al. Overexpression of microRNA- 146 protects against oxygen-glucose deprivation/recovery-induced cardiomyocyte apoptosis by inhibiting the NF-κB/TNF-α signaling pathway. Mol Med Rep. 2018;17(1):1913–1918.
  • Yang Y, Yang L, Cao Q, et al. Cryptotanshinone alleviates polycystic ovary syndrome in rats by regulating the HMGB1/TLR4/NF-κB signaling pathway [J]. Mol Med Rep. 2020;22(5):3851–3861.
  • Xie Y, Zhang K, Zhang K, et al. Toll-like receptors and high mobility group box 1 in granulosa cells during bovine follicle maturation. J Cell Physiol. 2020;235(4):3447–3462.
  • Gupta S, Lodha P, Karthick MS, et al. Role of Autologous Bone Marrow- Derived Stem Cell Therapy for Follicular Recruitment in Premature Ovarian Insufficiency: review of Literature and a Case Report of World’s First Baby with Ovarian Autologous Stem Cell Therapy in a Perimenopausal Woman of Age 45 Year. J Hum Reprod Sci. 2018;11(2):125–130.
  • Hikabe O, Hamazaki N, Nagamatsu G, et al. Reconstitution in vitro of the entire cycle of the mouse female germ line. Nature. 2016;539(7628):299–303.
  • Sciorio R, Tramontano L, Catt J. Preimplantation genetic diagnosis (PGD)and genetic testing for aneuploidy (PGT-A): status and future challenges. Gynecol Endocrinol. 2020;36(1):6–11.
  • Totonchi M, Babaabasi B, Najafi H, et al. Preimplantation Genetic Screening and The Success Rate of In Vitro Fertilization: a Three-Years Study on Iranian Population. Cell J. 2021;22(4):467–475.
  • Fu YX, Ji J, Shan F, et al. Human mesenchymal stem cell treatment of premature ovarian failure: new challenges and opportunities. Stem Cell Res Ther. 2021;12(1):161.
  • Yoon SY, Yoon JA, Park M, et al. Recovery of ovarian function by human embryonic stem cell-derived mesenchymal stem cells in cisplatin-induced premature ovarian failure in mice. Stem Cell Res Ther. 2020;11(1):255.
  • Jiang Y, Zhang Z, Cha L, et al. Resveratrol Plays a Protective Role against Premature Ovarian Failure and ProZmpts Female Germline Stem Cell Survival. Int J Mol Sci. 2019;20(14):3605.