Significant role of long non-coding RNA MALAT1 in deep vein thrombosis via the regulation of vascular endothelial cell physiology through the microRNA-383-5p/BCL2L11 axis

References

• Kruger PC, Eikelboom JW, Douketis JD, et al. Deep vein thrombosis: update on diagnosis and management. Med J Aust. 2019;210:516–524.
   PubMed Web of Science ®Google Scholar
• Chopard R, Albertsen IE, Piazza G. Diagnosis and treatment of lower extremity venous thromboembolism: a review. JAMA. 2020;324:1765–1776.
   PubMed Web of Science ®Google Scholar
• White RH. The epidemiology of venous thromboembolism. Circulation. 2003;107:I4–8.
   PubMed Web of Science ®Google Scholar
• Di Nisio M, van Es N, Büller HR. Deep vein thrombosis and pulmonary embolism. Lancet. 2016;388:3060–3073.
   PubMed Web of Science ®Google Scholar
• Cushman M. Epidemiology and risk factors for venous thrombosis. Semin Hematol. 2007;44:62–69.
   PubMed Web of Science ®Google Scholar
• Turetz M, Sideris AT, Friedman OA, et al. Epidemiology, pathophysiology, and natural history of pulmonary embolism. Semin Intervent Radiol. 2018;35:92–98.
   PubMed Web of Science ®Google Scholar
• Bochenek ML, Schütz E, Schäfer K. Endothelial cell senescence and thrombosis: ageing clots. Thromb Res. 2016;147:36–45.
   PubMed Web of Science ®Google Scholar
• Sepúlveda C, Palomo I, Fuentes E. Mechanisms of endothelial dysfunction during aging: predisposition to thrombosis. Mech Ageing Dev. 2017;164:91–99.
   PubMed Web of Science ®Google Scholar
• Silva GC, Abbas M, Khemais-Benkhiat S, et al. Replicative senescence promotes prothrombotic responses in endothelial cells: role of NADPH oxidase- and cyclooxygenase-derived oxidative stress. Exp Gerontol. 2017;93:7–15.
   PubMed Web of Science ®Google Scholar
• Prasad M, McBane R, Reriani M, et al. Coronary endothelial dysfunction is associated with increased risk of venous thromboembolism. Thromb Res. 2016;139:17–21.
   PubMed Web of Science ®Google Scholar
• Poredos P, Jezovnik MK. Endothelial dysfunction and venous thrombosis. Angiology. 2018;69:564–567.
   PubMed Web of Science ®Google Scholar
• Kung JT, Colognori D, Lee JT. Long noncoding RNAs: past, present, and future. Genetics. 2013;193:651–669.
   PubMed Web of Science ®Google Scholar
• Yang S, Zheng Y, Hou X. Lipoxin A4 restores oxidative stress-induced vascular endothelial cell injury and thrombosis-related factor expression by its receptor-mediated activation of Nrf2-HO-1 axis. Cell Signal. 2019;60:146–153.
   PubMed Web of Science ®Google Scholar
• Chen L, Wang J, Wang B, et al. MiR-126 inhibits vascular endothelial cell apoptosis through targeting PI3K/Akt signaling. Ann Hematol. 2016;95:365–374.
   PubMed Web of Science ®Google Scholar
• Shyy JY, Chien S. Role of integrins in endothelial mechano- sensing of shear stress. Circ Res. 2002;91:769–775.
   PubMed Web of Science ®Google Scholar
• Bombeli T, Karsan A, Tait JF, et al. Apoptotic vascular endothelial cells become procoagulant. Blood. 1997;89:2429–2442.
   PubMed Web of Science ®Google Scholar
• Mo J, Huang H, He F, et al. Influence of apoptosis signal pathway in traumatic deep vein thrombosis. J Kunming Med Univ. 2007;28:5–7.
   Google Scholar
• Jin J, Wang C, Ouyang Y, et al. Elevated miR-195-5p expression in deep vein thrombosis and mechanism of action in the regulation of vascular endothelial cell physiology. Exp Ther Med. 2019;18:4617–4624.
   PubMed Web of Science ®Google Scholar
• Kung JT, Colognori D, Lee JT. Long noncoding RNAs: past, present, and future. Genetics. 2013;193:651–669.
   PubMed Web of Science ®Google Scholar
• Lekka E, Hall J. Noncoding RNAs in disease. FEBS Lett. 2018;592:2884–2900.
   PubMed Web of Science ®Google Scholar
• Kopp F, Mendell JT. Functional classification and experimental dissection of long noncoding RNAs. Cell. 2018;172:393–407.
   PubMed Web of Science ®Google Scholar
• Lou Z, Zhu J, Li X, et al. LncRNA Sirt1-AS upregulates Sirt1 to attenuate aging related deep venous thrombosis. Aging (Albany NY). 2021;13:6918–6935.
   PubMedGoogle Scholar
• Ji P, Diederichs S, Wang W, et al. MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene. 2003;22:8031–8041.
   PubMed Web of Science ®Google Scholar
• Liu H, Chi ZF, Jin H, et al. MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma. Bioengineered. 2021;12:1611–1626.
   PubMed Web of Science ®Google Scholar
• Cheng Y, Imanirad P, Jutooru I, et al. Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer. PloS ONE. 2018;13:e0192264.
   PubMed Web of Science ®Google Scholar
• Chen D, Liu L, Wang K, et al. The role of MALAT-1 in the invasion and metastasis of gastric cancer. Scand J Gastroenterol. 2017;52:790–796.
   PubMed Web of Science ®Google Scholar
• Gao Q, Wang Y. Long noncoding RNA MALAT1 regulates apoptosis in ischemic stroke by sponging miR-205-3p and modulating PTEN expression. Am J Translat Res. 2020;12:2738–2748.
   PubMed Web of Science ®Google Scholar
• Theo FJ, Kraus H, Melanie S, et al. Altered long noncoding RNA expression precedes the course of Parkinson’s disease-a preliminary report. Mol Neurobiol. 2017;54:2869–2877.
   PubMed Web of Science ®Google Scholar
• Du B, Wang J, Zang S, et al. Long non-coding RNA MALAT1 suppresses the proliferation and migration of endothelial progenitor cells in deep vein thrombosis by regulating the Wnt/β-catenin pathway. Exp Ther Med. 2020; 205:3138–3146.
   PubMed Web of Science ®Google Scholar
• Seungil R, Chanjae P, David Y, et al. Tissue-dependent paired expression of miRNAs. Nucleic Acids Res. 2007;35:5944–5953.
   PubMed Web of Science ®Google Scholar
• Mallory AC, Vaucheret H. MicroRNAs: something important between the genes. Curr Opin Plant Biol. 2004;7:120–125.
   PubMed Web of Science ®Google Scholar
• Garzon R, Calin GA, Croce CM. MicroRNAs in cancer. Annu Rev Med. 2009;60:167–179.
   PubMed Web of Science ®Google Scholar
• Jiang J, Xie C, Liu Y, et al. Up-regulation of miR-383-5p suppresses proliferation and enhances chemosensitivity in ovarian cancer cells by targeting TRIM27. Biomed Pharmacother. 2019;109:595–601.
   PubMed Web of Science ®Google Scholar
• Hu Y, Ma Y, Liu J, et al. LINC01128 expedites cervical cancer progression by regulating miR-383-5p/SFN axis. BMC Cancer. 2019;19:1157.
   PubMed Web of Science ®Google Scholar
• Xu G, Li N, Zhang Y, et al. MicroRNA-383-5p inhibits the progression of gastric carcinoma via targeting HDAC9 expression. Braz J Med Biol Res. 2019;52:e8341.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods. 2001;25:402–408.
   PubMed Web of Science ®Google Scholar
• Kumar P, Nagarajan A, Uchil PD. Analysis of cell viability by the MTT assay. Cold Spring Harb Protoc. 2018;2018:469–471.
   Google Scholar
• Wu X, Li Q, Zhang F, et al. Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells. Food Chem Toxicol. 2021;147:111892.
   PubMed Web of Science ®Google Scholar
• Kim B. Western Blot Techniques. Methods Mol Biol. 2017;1606:133–139.
   PubMedGoogle Scholar
• Solberg N, Krauss S. Luciferase assay to study the activity of a cloned promoter DNA fragment. Methods Mol Biol. 2013;977:65–78.
   PubMedGoogle Scholar
• Sáez-Giménez B, Berastegui C, Loor K, et al. Deep vein thrombosis and pulmonary embolism after solid organ transplantation: an unresolved problem. Transplant Rev (Orlando). 2015;29:85–92.
   PubMedGoogle Scholar
• Weitz JI, Eikelboom JW, Samama MM. New antithrombotic drugs: antithrombotic therapy and prevention of thrombosis, 9th ed: American college of chest physicians evidence-based clinical practice guidelines. Chest. 2012;141(Suppl 2):e120S–e151S.
   PubMed Web of Science ®Google Scholar
• Sun LL, Lei FR, Jiang XD, et al. LncRNA GUSBP5-AS promotes EPC migration and angiogenesis and deep vein thrombosis resolution by regulating FGF2 and MMP2/9 through the miR-223-3p/FOXO1/Akt pathway. Aging (Albany NY). 2020;12(5):4506–4526.
   PubMedGoogle Scholar
• Long B, Li N, Xu XX, et al. Long noncoding RNA LOXL1-AS1 regulates prostate cancer cell proliferation and cell cycle progression through miR-541-3p and CCND1. Biochem Biophys Res Commun. 2018;505:561–568.
   PubMed Web of Science ®Google Scholar
• Lv K, Liu Y, Zheng Y, et al. Long non‐coding RNA MALAT1 regulates cell proliferation and apoptosis via miR-135b-5p/GPNMB axis in Parkinson’s disease cell model. Biol Res. 2021;54(1):10.
   PubMed Web of Science ®Google Scholar
• Jia Y, Yi L, Li Q, et al. LncRNA MALAT1 aggravates oxygen‐glucose deprivation/reoxygenation-induced neuronal endoplasmic reticulum stress and apoptosis via the miR-195a-5p/HMGA1 axis. Biol Res. 2021;54(1):8.
   PubMed Web of Science ®Google Scholar
• Mu X, Wu H, Liu J, et al. Long noncoding RNA TMPO-AS1 promotes lung adenocarcinoma progression and is negatively regulated by miR-383-5p. Biomed Pharmacother. 2020;125: 109989.
   PubMed Web of Science ®Google Scholar
• Liu G, Yang H, Cao L, et al. LncRNA TMPO-AS1 promotes proliferation and invasion by sponging miR-383-5p in glioma cells. Cancer Manag Res. 2020;12:12001–12009.
   PubMed Web of Science ®Google Scholar
• Wang X, Xu D, Pei X, et al. CircSKA3 modulates FOXM1 to facilitate cell proliferation, migration, and invasion while confine apoptosis in medulloblastoma via miR-383-5p. Cancer Manag Res. 2020;12:13415–13426.
   PubMed Web of Science ®Google Scholar
• Dai Y, Grant S. BCL2L11/Bim as a dual-agent regulating autophagy and apoptosis in drug resistance. Autophagy. 2015;11:416–418.
   PubMed Web of Science ®Google Scholar
• Luo S, Rubinsztein DC. BCL2L11/BIM: a novel molecular link between autophagy and apoptosis. Autophagy. 2013;9:104–105.
   PubMed Web of Science ®Google Scholar
• Wood CD, Veenstra H, Khasnis S, et al. MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer promoter hubs. Elife. 2016;5:e18270.
   PubMed Web of Science ®Google Scholar
• Tang W, Li J, Liu H, et al. MiR-106a promotes tumor growth, migration, and invasion by targeting BCL2L11 in human endometrial adenocarcinoma. Am J Transl Res. 2017;11(9):4984–4993.
   Google Scholar
• Chen J, Lin Y, Jia Y, et al. LncRNA HAND2-AS1 exerts anti-oncogenic effects on ovarian cancer via restoration of BCL2L11 as a sponge of microRNA-340-5p. J Cell Physiol. 2019;234:23421–23436.
   PubMed Web of Science ®Google Scholar
• Shen Z, Chen X, Li Q, et al. TGFB2 and BCL2L11 methylation in male laryngeal cancer patients. Oncol Lett. 2016;12:2999–3003.
   PubMed Web of Science ®Google Scholar