In vivo and in vitro studies of Alloimperatorin induced autophagy in cervical cancer cells via reactive oxygen species pathway

References

• Hoque MR, Haque E, Karim MR. Cervical cancer in low-income countries: a Bangladeshi perspective. Int J Gynaecol Obstet. 2021;152(1):19–25.
   PubMed Web of Science ®Google Scholar
• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Nagao S, Yamamoto K, Oishi T, et al. Phase II study of a new multidisciplinary therapy using once every 3 week carboplatin plus dose-dense weekly paclitaxel before and after radical hysterectomy for locally advanced cervical cancer. Int J Clin Oncol. 2021;26(1):207–215.
   PubMed Web of Science ®Google Scholar
• de Sá Junior PL, Câmara DAD, Porcacchia AS, et al. The roles of ROS in cancer heterogeneity and therapy. Oxid Med Cell Longev. 2017;2017:2467940.
   PubMed Web of Science ®Google Scholar
• Zou Z, Chang H, Li H, et al. Induction of reactive oxygen species: an emerging approach for cancer therapy. Apoptosis. 2017;22(11):1321–1335.
   PubMed Web of Science ®Google Scholar
• Fang J, Nakamura H, Iyer AK. Tumor-targeted induction of oxystress for cancer therapy. J Drug Target. 2007;15(7–8):475–486.
   PubMed Web of Science ®Google Scholar
• Simonsen A, Tooze SA. Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol. 2009;186(6):773–782.
   PubMed Web of Science ®Google Scholar
• Mizushima N, Levine B, Cuervo AM, et al. Autophagy fights disease through cellular self-digestion. Nature. 2008;451(7182):1069–1075.
   PubMed Web of Science ®Google Scholar
• Thorburn A, Thamm DH, Gustafson DL. Autophagy and cancer therapy. Mol Pharmacol. 2014;85(6):830–838.
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Bravo-San Pedro JM, Vitale I, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 2015;22(1):58–73.
   PubMed Web of Science ®Google Scholar
• Tsai JH, Hsu LS, Huang HC, et al. 1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione induces G1 cell cycle arrest and autophagy in HeLa cervical cancer cells. Int J Mol Sci. 2016;17(8):1274.
   PubMed Web of Science ®Google Scholar
• Celesia A, Morana O, Fiore T, et al. ROS-Dependent ER stress and autophagy mediate the anti-tumor effects of tributyltin (IV) ferulate in colon cancer cells. Int J Mol Sci. 2020;21(21):8135.
   PubMed Web of Science ®Google Scholar
• Gong H. Pinocembrin suppresses proliferation and enhances apoptosis in lung cancer cells in vitro by restraining autophagy. Bioengineered. 2021;12(1):6035–6044.
   PubMed Web of Science ®Google Scholar
• Li C, Liu S, Zheng J, et al. Angelica sinensis polysaccharide (ASP) attenuates diosbulbin-B (DB)-induced hepatotoxicity through activating the MEK/ERK pathway. Bioengineered. 2021;12(1):3516–3524.
   PubMed Web of Science ®Google Scholar
• Ji Y, Hu W, Jin Y, et al. Liquiritigenin exerts the anti-cancer role in oral cancer via inducing autophagy-related apoptosis through PI3K/AKT/mTOR pathway inhibition in vitro and in vivo. Bioengineered. 2021;12(1):6070–6082.
   PubMed Web of Science ®Google Scholar
• White E. Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer. 2012;12(6):401–410.
   PubMed Web of Science ®Google Scholar
• Amaravadi R, Kimmelman AC, White E. Recent insights into the function of autophagy in cancer. Genes Dev. 2016;30(17):1913–1930.
   PubMed Web of Science ®Google Scholar
• Deng GG, Yang XW, Zhang YB, et al. Chemical constituents from lipophilic parts in roots of Angelica dahurica cv.Yubaizhi. Zhongguo Zhong Yao Za Zhi. 2017;42(11):2102–2109.
   PubMedGoogle Scholar
• Deng GG, Yang XW, Zhang YB, et al. Chemical constituents from lipophilic parts in roots of Angelica dahurica var. formosana cv. Chuanbaizhi. Zhongguo Zhong Yao Za Zhi. 2015;40(11):2148–2156.
   PubMedGoogle Scholar
• Chen Q, Li P, He J, et al. Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS. J Sep Sci. 2008;31(18):3218–3224.
   PubMed Web of Science ®Google Scholar
• Zheng YM, Shen JZ, Wang Y, et al. Anti-oxidant and anti-cancer activities of Angelica dahurica extract via induction of apoptosis in colon cancer cells. Phytomedicine. 2016;23(11):1267–1274.
   PubMed Web of Science ®Google Scholar
• Zhang L, Tong X, Zhang J, et al. DAW22, a natural sesquiterpene coumarin isolated from Ferula ferulaeoides (Steud.) Korov. that induces C6 glioma cell apoptosis and endoplasmic reticulum (ER) stress. Fitoterapia. 2015;103:46–54.
   PubMed Web of Science ®Google Scholar
• Pereira DI, Amparo TR, Almeida TC, et al. Cytotoxic activity of butanolic extract from Sambucus nigra L. flowers in natura and vehiculated in micelles in bladder cancer cells and fibroblasts. Nat Prod Res. 2022;36(4):1100–1104.
   PubMed Web of Science ®Google Scholar
• Mazur J, Zawadowski T, Kawiak J, et al. Synthesis of novel 4,4’-dimethylsfondine derivatives with potential photochemotherapeutic and antileukaemic activity. Acta poloniae pharmaceutica. 1994;51(6):475–477.
   PubMedGoogle Scholar
• Hwangbo H, Choi EO, Kim MY, et al. Suppression of tumor growth and metastasis by ethanol extract of Angelica dahurica Radix in murine melanoma B16F10 cells. Biosci Trends. 2020;14(1):23–34.
   PubMed Web of Science ®Google Scholar
• Kim YK, Kim YS, Ryu SY. Antiproliferative effect of furanocoumarins from the root of Angelica dahurica on cultured human tumor cell lines. Phytother Res. 2007;21(3):288–290.
   PubMed Web of Science ®Google Scholar
• Lyublinskaya OG, Ivanova JS, Pugovkina NA, et al. Redox environment in stem and differentiated cells: a quantitative approach. Redox Biol. 2017;12:758–769.
   PubMed Web of Science ®Google Scholar
• Hu Z, You P, Xiong S, et al. Carapax Trionycis extracts inhibit fibrogenesis of activated hepatic stellate cells via TGF-β1/Smad and NFκB signaling. Biomed Pharmacothe. 2017;95:11–17.
   PubMed Web of Science ®Google Scholar
• Fraietta I, Gasparri F. The development of high-content screening (HCS) technology and its importance to drug discovery. Expert Opin Drug Discov. 2016;11(5):501–514.
   PubMed Web of Science ®Google Scholar
• Cui D, Zhang C, Liu B, et al. Regression of gastric cancer by systemic injection of RNA nanoparticles carrying both ligand and siRNA. Sci Rep. 2015;5:10726.
   PubMed Web of Science ®Google Scholar
• Pan H, Wang Y, Na K, et al. Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation. Cell Death Dis. 2019;10(6):456.
   PubMedGoogle Scholar
• Zhang Y, Liu D, Hu H, et al. HIF-1α/BNIP3 signaling pathway-induced-autophagy plays protective role during myocardial ischemia-reperfusion injury. Biomed Pharmacothe. 2019;120:109464.
   PubMed Web of Science ®Google Scholar
• Galadari S, Rahman A, Pallichankandy S, et al. Reactive oxygen species and cancer paradox: to promote or to suppress? Free Radic Biol Med. 2017;104:144–164.
   PubMed Web of Science ®Google Scholar
• Lamark T, Kirkin V, Dikic I, et al. NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets. Cell Cycle (Georgetown, Tex). 2009;8(13):1986–1990.
   PubMed Web of Science ®Google Scholar
• Tanida I. Autophagosome formation and molecular mechanism of autophagy. Antioxid Redox Signal. 2011;14(11):2201–2214.
   PubMed Web of Science ®Google Scholar
• Adiseshaiah PP, Skoczen SL, Rodriguez JC, et al. Autophagy monitoring assay II: imaging autophagy induction in LLC-PK1 cells using GFP-LC3 protein fusion construct. Methods Mol Biol. 2018;1682:211–219.
   PubMedGoogle Scholar
• Yan Z, Lai Z, Lin J. Anticancer properties of traditional Chinese medicine. Comb Chem High Throughput Screen. 2017;20(5):423–429.
   PubMed Web of Science ®Google Scholar
• Li DY, Yue LX, Wang SG, et al. Quercitrin restrains the growth and invasion of lung adenocarcinoma cells by regulating gap junction protein beta 2. Bioengineered. 2022;13(3):6126–6135.
   PubMed Web of Science ®Google Scholar
• Sun Q, He M, Zhang M, et al. Traditional Chinese medicine and colorectal cancer: implications for drug discovery. Front Pharmacol. 2021;12:685002.
   PubMed Web of Science ®Google Scholar
• Bai Y, Yang L, Zhang C, et al. Studies on the mechanism of Alloimperatorin on the proliferation and apoptosis of HeLa cells. J Oncol. 2021;2021:6617312.
   PubMed Web of Science ®Google Scholar
• Gao L, Loveless J, Shay C, et al. Targeting ROS-mediated crosstalk between autophagy and apoptosis in cancer. Adv Exp Med Biol. 2020;1260:1–12.
   PubMed Web of Science ®Google Scholar
• Law BY, Mok SW, Wu AG, et al. New potential pharmacological functions of Chinese herbal medicines via regulation of autophagy. Molecules. 2016;21(3):359.
   PubMed Web of Science ®Google Scholar
• Luo Z, Xu X, Sho T, et al. ROS-induced autophagy regulates porcine trophectoderm cell apoptosis, proliferation, and differentiation. Am J Physiol Cell Physiol. 2019;316(2):C198–c209.
   PubMed Web of Science ®Google Scholar
• Iqbal J, Kucuk C, Deleeuw RJ, et al. Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia. 2009;23(6):1139–1151.
   PubMed Web of Science ®Google Scholar
• Huang X, Bai HM, Chen L, et al. Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors. J Clin Neurosci. 2010;17(12):1515–1519.
   PubMed Web of Science ®Google Scholar
• Muñoz-Sánchez S, van der Vaart M, Meijer AH. Autophagy and Lc3-associated phagocytosis in zebrafish models of bacterial infections. Cells. 2020;9(11):2372.
   PubMed Web of Science ®Google Scholar