Approaches for neutrophil imaging: an important step in personalized medicine

References

• Kanwore K, Kanwore K, Adzika GK, et al. Cancer metabolism: the role of immune cells epigenetic alteration in tumorigenesis, progression, and metastasis of glioma. Front Immunol. 2022;13:831636.
   PubMed Web of Science ®Google Scholar
• Ma Q, Immler R, Pruenster M, et al. Soluble uric acid inhibits beta2 integrin-mediated neutrophil recruitment in innate immunity. Blood. 2022;139:3402–3417.
   PubMed Web of Science ®Google Scholar
• Mahmud Z, Rahman A, Mishu ID, et al. Mechanistic insights into the interplays between neutrophils and other immune cells in cancer development and progression. Cancer Metastasis Rev. 2022;41:405–432.
   PubMed Web of Science ®Google Scholar
• Ye D, Yao J, Du W, et al. Neutrophil extracellular traps mediate acute liver failure in regulation of miR-223/neutrophil elastase signaling in mice. Cell Mol Gastroenterol Hepatol. 2022;14:587–607.
   PubMed Web of Science ®Google Scholar
• Jiang ZZ, Peng ZP, Liu XC, et al. Neutrophil extracellular traps induce tumor metastasis through dual effects on cancer and endothelial cells. Oncoimmunology. 2022;11:2052418.
   PubMed Web of Science ®Google Scholar
• Tsukasaki Y, Toth PT, Davoodi-Bojd E, et al. Quantitative pulmonary neutrophil dynamics using computer-vision stabilized intravital imaging. Am J Respir Cell Mol Biol. 2022;66:12–22.
   PubMed Web of Science ®Google Scholar
• Zhang X, Jiang C, He T, et al. Engineering molecular probes for in vivo near-infrared fluorescence/photoacoustic duplex imaging of human neutrophil elastase. Anal Chem. 2022;94:3227–3234.
   PubMed Web of Science ®Google Scholar
• Tang C, Wang Q, Li K, et al. A neutrophil-mimetic magnetic nanoprobe for molecular magnetic resonance imaging of stroke-induced neuroinflammation. Biomater Sci. 2021;9:5247–5258.
   PubMed Web of Science ®Google Scholar
• Mirili C, Guney IB, Paydas S, et al. Prognostic significance of neutrophil/lymphocyte ratio (NLR) and correlation with PET-CT metabolic parameters in small cell lung cancer (SCLC). Int J Clin Oncol. 2019;24:168–178.
   PubMed Web of Science ®Google Scholar
• Alagappan M, Pollom EL, von Eyben R, et al. Albumin and Neutrophil-Lymphocyte Ratio (NLR) predict survival in patients with pancreatic adenocarcinoma treated with SBRT. Am J Clin Oncol. 2018;41:242–247.
   PubMed Web of Science ®Google Scholar
• Pemberton HG, Collij LE, Heeman F, et al. Quantification of amyloid PET for future clinical use: a state-of-the-art review. Eur J Nucl Med Mol Imaging. 2022;49:3508–3528.
   PubMed Web of Science ®Google Scholar
• Filippi L, Schillaci O. Total-body [(18)F]FDG PET/CT scan has stepped into the arena: the faster, the better. Is it always true? Eur J Nucl Med Mol Imaging. 2022;49:3322–3327.
   PubMed Web of Science ®Google Scholar
• Schwenck J, Schorg B, Fiz F, et al. Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo (18)F-FDG-PET. Theranostics. 2020;10:925–937.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhao N, Wu Z, et al. New insight on the correlation of metabolic status on (18)F-FDG PET/CT with immune marker expression in patients with non-small cell lung cancer. Eur J Nucl Med Mol Imaging. 2020;47:1127–1136.
   PubMed Web of Science ®Google Scholar
• Xu J, Li Y, Hu S, et al. The significant value of predicting prognosis in patients with colorectal cancer using (18)F-FDG PET metabolic parameters of primary tumors and hematological parameters. Ann Nucl Med. 2019;33:32–38.
   PubMed Web of Science ®Google Scholar
• Sanduleanu S, Jochems A, Upadhaya T, et al. Non-invasive imaging prediction of tumor hypoxia: a novel developed and externally validated CT and FDG-PET-based radiomic signatures. Radiother Oncol. 2020;153:97–105.
   PubMed Web of Science ®Google Scholar
• Kinoshita T, Fujii H, Hayashi Y, et al. Prognostic significance of hypoxic PET using (18)F-FAZA and (62)Cu-ATSM in non-small-cell lung cancer. Lung Cancer. 2016;91:56–66.
   PubMed Web of Science ®Google Scholar
• Alongi P, Laudicella R, Lanzafame H, et al. PSMA and choline PET for the assessment of response to therapy and survival outcomes in prostate cancer patients: a systematic review from the literature. Cancers (Basel). 2022;14:1770.
   PubMed Web of Science ®Google Scholar
• Park JA, Lee YJ, Lee JW, et al. Evaluation of [(89)Zr]-Oxalate as a PET tracer in inflammation, tumor, and rheumatoid arthritis models. Mol Pharm. 2016;13:2571–2577.
   PubMedGoogle Scholar
• Cristinziano L, Modestino L, Antonelli A, et al. Neutrophil extracellular traps in cancer. Semin Cancer Biol. 2022;79:91–104.
   PubMed Web of Science ®Google Scholar
• Locke LW, Chordia MD, Zhang Y, et al. A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu. J Nucl Med. 2009;50:790–797.
   PubMed Web of Science ®Google Scholar
• Pellico J, Lechuga-Vieco AV, Almarza E, et al. In vivo imaging of lung inflammation with neutrophil-specific (68)Ga nano-radiotracer. Sci Rep. 2017;7:13242.
   PubMed Web of Science ®Google Scholar
• Kong Y, Liu K, Hua T, et al. PET imaging of neutrophils infiltration in Alzheimer’s DISEASE TRANSGENIC MICE. Front Neurol. 2020;11:523798.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Xiao L, Chordia MD, et al. Neutrophil targeting heterobivalent SPECT imaging probe: cFLFLF-PEG-TKPPR-99mTc. Bioconjug Chem. 2010;21:1788–1793.
   PubMed Web of Science ®Google Scholar
• Chen J, Cheng H, Dong Q, et al. [99mTc]cFLFLF for early diagnosis and therapeutic evaluation in a rat model of acute osteomyelitis. Mol Imaging Biol. 2015;17:337–344.
   PubMed Web of Science ®Google Scholar
• Xiao L, Ding M, Zhang Y, et al. A novel modality for functional imaging in acute intervertebral disk herniation via tracking leukocyte infiltration. Mol Imaging Biol. 2017;19:703–713.
   PubMed Web of Science ®Google Scholar
• Dudchenko N, Pawar S, Perelshtein I, et al. Magnetite nanoparticles: synthesis and applications in optics and nanophotonics. Materials (Basel). 2022;15:2601 .
   PubMed Web of Science ®Google Scholar
• Savla R, Minko T. Nanoparticle design considerations for molecular imaging of apoptosis: diagnostic, prognostic, and therapeutic value. Adv Drug Deliv Rev. 2017;113:122–140.
   PubMed Web of Science ®Google Scholar
• Thiruppathi R, Mishra S, Ganapathy M, et al. Nanoparticle functionalization and its potentials for molecular imaging. Adv Sci (Weinh). 2017;4:1600279.
   PubMedGoogle Scholar
• Cerqueira M, Belmonte-Reche E, Gallo J, et al. Magnetic solid nanoparticles and their counterparts: recent advances towards cancer theranostics. Pharmaceutics. 2022;14:506.
   PubMed Web of Science ®Google Scholar
• Lin PC, Lin S, Wang PC, et al. Techniques for physicochemical characterization of nanomaterials. Biotechnol Adv. 2014;32:711–726.
   PubMed Web of Science ®Google Scholar
• Vishnevskiy DA, Garanina AS, Chernysheva AA, et al. Neutrophil and nanoparticles delivery to tumor: is it going to carry that weight? Adv Healthc Mater. 2021;10:e2002071.
   PubMed Web of Science ®Google Scholar
• Lyu J, Wang L, Bai X, et al. Treatment of rheumatoid arthritis by serum albumin nanoparticles coated with mannose to target neutrophils. ACS Appl Mater Interfaces. 2021;13:266–276.
   PubMed Web of Science ®Google Scholar
• Singh S, Zhang XHF, Rosen JM. TIME is a great healer-targeting myeloid cells in the tumor immune microenvironment to improve triple-negative breast cancer outcomes. Cells. 2020;10.
   Web of Science ®Google Scholar
• Qiu Q, Wen Y, Dong H, et al. A highly sensitive living probe derived from nanoparticle-remodeled neutrophils for precision tumor imaging diagnosis. Biomater Sci. 2019;7:5211–5220.
   PubMed Web of Science ®Google Scholar
• Sun R, Wang X, Nie Y, et al. Targeted trapping of endogenous endothelial progenitor cells for myocardial ischemic injury repair through neutrophil-mediated SPIO nanoparticle-conjugated CD34 antibody delivery and imaging. Acta Biomater. 2022;146:421–433. doi:10.1016/j.actbio.2022.05.003.
   PubMed Web of Science ®Google Scholar
• Zheng H, Yuan C, Cai J, et al. Early diagnosis of breast cancer lung metastasis by nanoprobe-based luminescence imaging of the pre-metastatic niche. J Nanobiotechnology. 2022;20:134. doi:10.1186/s12951-022-01346-4.
   PubMed Web of Science ®Google Scholar
• Yan X, Lin W, Liu H, et al. Wavelength-Tunable, Long Lifetime, and Biocompatible Luminescent Nanoparticles Based on a Vitamin E-Derived Material for Inflammation and Tumor Imaging. Small. 2021;17:e2100045. doi:10.1002/smll.202100045.
   PubMed Web of Science ®Google Scholar
• Chandrasekharan P, Fung KLB, Zhou XY, et al. Non-radioactive and sensitive tracking of neutrophils towards inflammation using antibody functionalized magnetic particle imaging tracers. Nanotheranostics. 2021;5:240–55. doi:10.7150/ntno.50721.
   PubMedGoogle Scholar
• Penate-Medina T, Damoah C, Benezra M, et al. Alpha-MSH Targeted Liposomal Nanoparticle for Imaging in Inflammatory Bowel Disease (IBD). Curr Pharm Des. 2020;26:3840–6. doi:10.2174/1381612826666200727002716.
   PubMed Web of Science ®Google Scholar
• Tang L, Wang Z, Mu Q, et al. Targeting Neutrophils for Enhanced Cancer Theranostics. Adv Mater. 2020;32:e2002739. doi:10.1002/adma.202002739.
   PubMed Web of Science ®Google Scholar
• Tang C, Wang C, Zhang Y, et al. Recognition, Intervention, and Monitoring of Neutrophils in Acute Ischemic Stroke. Nano Lett. 2019;19:4470–7. doi:10.1021/acs.nanolett.9b01282.
   PubMed Web of Science ®Google Scholar
• Kirschbaum K, Sonner JK, Zeller MW, et al. In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis. Proc Natl Acad Sci U S A. 2016;113:13227–13232.
   PubMed Web of Science ®Google Scholar
• Wu M, Zhang H, Tie C, et al. MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma. Nat Commun. 2018;9:4777.
   PubMed Web of Science ®Google Scholar
• Qiu Y, Palankar R, Echeverria M, et al. Design of hybrid multimodal poly(lactic-co-glycolic acid) polymer nanoparticles for neutrophil labeling, imaging and tracking. Nanoscale. 2013;5:12624–12632.
   PubMed Web of Science ®Google Scholar
• Liu X, Wu M, Wang M, et al. AIEgen-Lipid conjugate for rapid labeling of neutrophils and monitoring of their behavior. Angew Chem Int Ed Engl. 2021;60:3175–3181.
   PubMed Web of Science ®Google Scholar
• Pardo A, Gomez-Florit M, Barbosa S, et al. Magnetic nanocomposite hydrogels for tissue engineering: design concepts and remote actuation strategies to control cell fate. ACS Nano. 2021;15:175–209.
   PubMed Web of Science ®Google Scholar
• Wang Q, Ren Y, Mu J, et al. Grapefruit-Derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites. Cancer Res. 2015;75:2520–2529.
   PubMed Web of Science ®Google Scholar
• Kang T, Zhu Q, Wei D, et al. Nanoparticles coated with neutrophil membranes can effectively treat cancer metastasis. ACS Nano. 2017;11:1397–1411.
   PubMed Web of Science ®Google Scholar
• Phipps MC, Huang Y, Yamaguchi R, et al. In vivo monitoring of activated macrophages and neutrophils in response to ischemic osteonecrosis in a mouse model. J Orthop Res. 2016;34:307–313.
   PubMed Web of Science ®Google Scholar
• Sun L, Zhou JE, Luo T, et al. Nanoengineered neutrophils as a cellular sonosensitizer for visual sonodynamic therapy of malignant tumors. Adv Mater. 2022;34:e2109969.
   PubMed Web of Science ®Google Scholar
• Garcia-Mendoza MG, Inman DR, Ponik SM, et al. Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment. Breast Cancer Res. 2016;18:49.
   PubMed Web of Science ®Google Scholar
• Nguyen CT, Furuya H, Das D, et al. Peripheral gammadelta T cells regulate neutrophil expansion and recruitment in experimental psoriatic arthritis. Arthritis Rheumatol. 2022;74:1524–1534.
   PubMed Web of Science ®Google Scholar
• Chu KK, Kusek ME, Liu L, et al. Illuminating dynamic neutrophil trans-epithelial migration with micro-optical coherence tomography. Sci Rep. 2017;8:45789.
   PubMedGoogle Scholar
• Turk M, Naumenko V, Mahoney DJ, et al. Tracking cell recruitment and behavior within the tumor microenvironment using advanced intravital imaging approaches. Cells. 2018;7:69.
   PubMed Web of Science ®Google Scholar
• Wang G, Nauseef WM. Neutrophil dysfunction in the pathogenesis of cystic fibrosis. Blood. 2022;139:2622–2631.
   PubMed Web of Science ®Google Scholar
• Kargapolova Y, Geissen S, Zheng R, et al. The enzymatic and non-enzymatic function of Myeloperoxidase (MPO) in inflammatory communication. Antioxidants (Basel). 2021;10. DOI:10.3390/antiox10040562
   PubMedGoogle Scholar
• Zhang N, Aiyasiding X, Li WJ, et al. Neutrophil degranulation and myocardial infarction. Cell Commun Signal. 2022;20:50.
   PubMed Web of Science ®Google Scholar
• Campuzano S, Pedrero M, Yanez-Sedeno P, et al. Nanozymes in electrochemical affinity biosensing. Mikrochim Acta. 2020;187:423.
   PubMed Web of Science ®Google Scholar
• Pulli B, Wojtkiewicz G, Iwamoto Y, et al. Molecular MR imaging of myeloperoxidase distinguishes steatosis from steatohepatitis in nonalcoholic fatty liver disease. Radiology. 2017;284:390–400.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Seeburg DP, Pulli B, et al. Myeloperoxidase nuclear imaging for epileptogenesis. Radiology. 2016;278:822–830.
   PubMed Web of Science ®Google Scholar
• Wang C, Keliher E, Zeller MWG, et al. An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo. Proc Natl Acad Sci U S A. 2019;116:11966–11971.
   PubMed Web of Science ®Google Scholar
• Wang C, Pulli B, Jalali Motlagh N, et al. A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales. Theranostics. 2019;9:7525–7536.
   PubMed Web of Science ®Google Scholar
• Huang M, Huang X, Huang N. Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells. Cancer Sci. 2022;113:1968–1983.
   PubMed Web of Science ®Google Scholar
• Gross S, Gammon ST, Moss BL, et al. Bioluminescence imaging of myeloperoxidase activity in vivo. Nat Med. 2009;15:455–461.
   PubMed Web of Science ®Google Scholar
• Blum C, Taskin MB, Shan J, et al. Appreciating the first line of the human innate immune defense: a strategy to model and alleviate the neutrophil elastase-mediated attack toward bioactivated biomaterials. Small. 2021;17:e2007551.
   PubMed Web of Science ®Google Scholar
• Margaroli C, Madison MC, Viera L, et al. An in vivo model for extracellular vesicle-induced emphysema. JCI Insight. 2022;7. DOI:10.1172/jci.insight.153560.
   PubMed Web of Science ®Google Scholar
• Zhang Y, He S, Xu C, et al. An activatable polymeric nanoprobe for fluorescence and photoacoustic imaging of tumor-associated neutrophils in cancer immunotherapy. Angew Chem Int Ed Engl. 2022;61:e202203184.
   PubMed Web of Science ®Google Scholar
• Mitra S, Modi KD, Foster TH. Enzyme-activatable imaging probe reveals enhanced neutrophil elastase activity in tumors following photodynamic therapy. J Biomed Opt. 2013;18:101314.
   PubMed Web of Science ®Google Scholar
• Zhang X, Baht GS, Huang R, et al. Rejuvenation of neutrophils and their extracellular vesicles is associated with enhanced aged fracture healing. Aging Cell. 2022;21:e13651.
   PubMed Web of Science ®Google Scholar
• Reeves BN, Beckman JD. Novel pathophysiological mechanisms of thrombosis in myeloproliferative neoplasms. Curr Hematol Malig Rep. 2021;16:304–313.
   PubMed Web of Science ®Google Scholar
• Urakawa S, Yamasaki M, Goto K, et al. Peri-operative monocyte count is a marker of poor prognosis in gastric cancer: increased monocytes are a characteristic of myeloid-derived suppressor cells. Cancer Immunol Immunother. 2019;68:1341–1350.
   PubMed Web of Science ®Google Scholar
• Okita Y, Tanaka H, Ohira M, et al. Role of tumor-infiltrating CD11b+ antigen-presenting cells in the progression of gastric cancer. J Surg Res. 2014;186:192–200.
   PubMed Web of Science ®Google Scholar
• Hoffmann SHL, Reck DI, Maurer A, et al. Visualization and quantification of in vivo homing kinetics of myeloid-derived suppressor cells in primary and metastatic cancer. Theranostics. 2019;9:5869–5885.
   PubMed Web of Science ®Google Scholar
• Tricarico D, Convertino AS, Mehmeti I, et al. Inflammatory related reactions in humans and in canine breast cancers, A spontaneous animal model of disease. Front Pharmacol. 2022;13:752098.
   PubMed Web of Science ®Google Scholar
• Georgantzoglou A, Coombs C, Poplimont H, et al. Live imaging of chemokine receptors in zebrafish neutrophils during wound responses. J Vis Exp. 2020. DOI:10.3791/61679
   PubMed Web of Science ®Google Scholar