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Review

Pathogenesis and treatment options for hemophilic synovitis

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Pages 173-179 | Received 18 Nov 2016, Accepted 03 Jan 2017, Published online: 12 Jan 2017

References

  • Roosendaal G, Lafeber FP. Blood-induced joint damage in hemophilia. Semin Thromb Hemost. 2003;29:37–42.
  • Rodriguez-Merchan EC. Management of musculoskeletal complications of hemophilia. Semin Thromb Hemost. 2003;29:87–96.
  • Rodriguez-Merchan EC. Pathogenesis, early diagnosis, and prophylaxis for chronic hemophilic synovitis. Clin Orthop Relat Res. 1997;343:6–11.
  • Rodriguez-Merchan EC. Effects of hemophilia on articulations of children and adults. Clin Orthop Relat Res. 1996;328:7–13.
  • Merchan EC, De Orbe A, Gago J. Ultrasound in the diagnosis of the early stages of hemophilic arthropathy of the knee. Acta Orthop Belg. 1992;58:122–125.
  • Rodriguez-Merchan EC. The destructive capabilities of the synovium in the haemophilic joint. Haemophilia. 1998;4:506–510.
  • Roosendaal G, Vianen ME, Marx JJ, et al. Blood-induced joint damage: a human in vitro study. Arthritis Rheum. 1999;42:1025–1032.
  • Blobel CP, Haxaire C, Kalliolias GD, et al. Blood-induced arthropathy in hemophilia: mechanisms and heterogeneity. Semin Thromb Hemost. 2015;41:832–837.
  • Hakobyan N, Kazarian T, Jabbar AA, et al. Pathobiology of hemophilic synovitis I: overexpression of mdm2 oncogene. Blood. 2004;104:2060–2064.
  • Roosendaal G, Lafeber FP. Pathogenesis of haemophilic arthropathy. Haemophilia. 2006;12(Suppl 3):117–121.
  • Valentino LA, Hakobyan N, Rodriguez N, et al. Pathogenesis of haemophilic synovitis: experimental studies on blood-induced joint damage. Haemophilia. 2007;13(Suppl 3):10–13.
  • Acharya SS, Kaplan RN, Macdonald D, et al. Neoangiogenesis contributes to the development of hemophilic synovitis. Blood. 2011;117:2484–2493.
  • Van Meegeren ME, Roosendaal G, Jansen NW, et al. Blood-induced joint damage: the devastating effects of acute joint bleeds versus micro-bleeds. Cartilage. 2013;4:313–320.
  • Srivastava A. Inflammation is key to haemophilic arthropathy. Blood. 2015;126:2175–2176.
  • Gilbert MS, Radomisli TE. Therapeutic options in the management of hemophilic synovitis. Clin Orthop Relat Res. 1997;343:88–92.
  • Rodriguez-Merchan EC, Valentino LA. Orthopedic disorders of the knee in hemophilia: A current concept review. World J Orthop. 2016;7:370–375.
  • Rodriguez-Merchan EC, De La Corte-Rodriguez H, Jimenez-Yuste V. Radiosynovectomy in haemophilia: long-term results of 500 procedures performed in a 38-year period. Thromb Res. 2014;134:985–990.
  • Rodriguez-Merchan EC. Methods to treat chronic haemophilic synovitis. Haemophilia. 2001;7:1–5.
  • Rodriguez-Merchan EC. Hemophilic synovitis of the knee: radiosynovectomy or arthroscopic synovectomy?. Expert Rev Hematol. 2014;7:507–511.
  • Infante-Rivard C, Rivard GE, Derome F, et al. A retrospective cohort study of cancer incidence among patients treated with radiosynoviorthesis. Haemophilia. 2012;18:805–809.
  • Rodriguez-Merchan EC, Valentino LA. Safety of radiation exposure after radiosynovectomy in paediatric patients with haemophilia. Haemophilia. 2015;21:411–418.
  • Manco-Johnson MJ, Nuss R, Lear J, et al. 32P Radiosynoviorthesis in children with hemophilia. J Pediatr Hematol Oncol. 2002;24:534–539.
  • Dunn AL, Manco-Johnson M, Busch MT, et al. Leukemia and P32 radionuclide synovectomy for hemophilic arthropathy. J Thromb Haemost. 2005;3:1541–1542.
  • De La Corte-Rodriguez H, Rodriguez-Merchan EC, Jimenez-Yuste V. Radiosynovectomy in hemophilia: quantification of its effectiveness through the assessment of 10 articular parameters. J Thromb Haemost. 2011;9:928–935.
  • Erken EH. Radiocolloids in the management of hemophilic arthropathy in children and adolescents. Clin Orthop Relat Res. 1991;264:129–135.
  • Merchan EC, Magallon M, Martin-Villar J, et al. Long term follow up of haemophilic arthropathy treated by Au-198 radiation synovectomy. Int Orthop. 1993;17:120–124.
  • Rivard GE, Girard M, Bélanger R, et al. Synoviorthesis with colloidal 32P chromic phosphate for the treatment of hemophilicarthropathy. J Bone Joint Surg Am. 1994;76:482–488.
  • Rodriguez-Merchan EC, Jimenez-Yuste V, Villar A, et al. Yttrium-90 synoviorthesis for chronic haemophilic synovitis: madrid experience. Haemophilia. 2001;7(Suppl 2):34–35.
  • Rodriguez-Merchan EC, Wiedel JD. General principles and indications of synoviorthesis (medical synovectomy) in haemophilia. Haemophilia. 2001;7(Suppl 2):6–10.
  • Rodriguez-Merchan EC, Goddard NJ. The technique of synoviorthesis. Haemophilia. 2001;7(Suppl 2):11–15.
  • Rodriguez-Merchan EC. Radionuclide synovectomy (radiosynoviorthesis) in hemophilia: a very efficient and single procedure. Semin Thromb Hemost. 2003;29:97–100.
  • Grmek M, Milcinski M, Fettich J, et al. Radiosynoviorthesis for treatment of hemophilic hemarthrosis–Slovenian experience. Cancer Biother Radiopharm. 2005;20:338–343.
  • Türkmen C, Zülflkar B, Taşer O, et al. Radiosynovectomy in hemophilic synovitis: correlation of therapeutic response and blood-pool changes. Cancer Biother Radiopharm. 2005;20:363–370.
  • Rodriguez-Merchan EC, Quintana M, De La Corte-Rodriguez H, et al. Radioactive synoviorthesis for the treatment of haemophilic synovitis. Haemophilia. 2007;13(Suppl 3):32–37.
  • De La Corte-Rodriguez H, Rodriguez-Merchan EC, Jimenez-Yuste V. What patient, joint and isotope characteristics influence the response to radiosynovectomy in patients with haemophilia?. Haemophilia. 2011;17:e990–8.
  • De La Corte-Rodriguez H, Rodriguez-Merchan EC, Jimenez-Yuste V. Consecutive radiosynovectomy procedures at 6-monthly intervals behave independently in haemophilic synovitis. Blood Transfus. 2013;11:254–259.
  • De La Corte-Rodriguez H, Rodriguez-Merchan EC, Jimenez-Yuste V. Radiosynovectomy in patients with chronic haemophilic synovitis: when is more than one injection necessary?. Eur J Haematol. 2011;86:430–435.
  • Rampersad AG, Shapiro AD, Rodriguez-Merchan EC, et al. Radiosynovectomy: review of the literature and report from two haemophilia treatment centers. Blood Coagul Fibrinolysis. 2013;24:465–470.
  • Rodriguez-Merchan EC, De La Corte-Rodriguez H, Jimenez-Yuste V. Is radiosynovectomy (RS) effective for joints damaged by haemophilia with articular degeneration in simple radiography (ADSR)?. Thromb Res. 2014;133:875–879.
  • Rodriguez-Merchan EC, De La Corte-Rodriguez H. Radiosynovectomy in haemophilic synovitis of elbows and ankles: is the effectiveness of yttrium-90 and rhenium-186 different?. Thromb Res. 2016;140:41–45.
  • Zhang WQ, Han SQ, Yuan Z, et al. Effects of intraarticular (32)P colloid in the treatment of hemophilic synovitis of the knee: A short term clinical study. Indian J Orthop. 2016;50:55–58.
  • Rivard GE, Girard M, Lamarre C, et al. Synoviorthesis with colloidal 32P chromic phosphate for hemophilic arthropathy: clinical follow-up. Arch Phys Med Rehabil. 1985;66:753–756.
  • Mortazavi SM, Asadollahi S, Farzan M, et al. (32)P colloid radiosynovectomy in treatment of chronic haemophilic synovitis: iran experience. Haemophilia. 2007;13:182–188.
  • Dunn AL, Busch MT, Wyly JB, et al. Radionuclide synovectomy for hemophilic arthropathy: a comprehensive review of safety and efficacy and recommendation for a standardized treatment protocol. Thromb Haemost. 2002;87:383–393.
  • Rodriguez-Merchan EC, Caviglia HA, Magallon M, et al. Chemical synovectomy vs. radioactive synovectomy for the treatment of chronic haemophilic synovitis: a prospective short-term study. Haemophilia. 1997;3:118–122.
  • Caviglia HA, Fernández-Palazzi F, Maffei E, et al. Chemical synoviorthesis for hemophilic synovitis. Clin Orthop Relat Res. 1997;343:30–36.
  • Wiedel JD. Arthroscopic synovectomy for chronic hemophilic synovitis of the knee. Arthroscopy. 1985;1:205–209.
  • Klein KS, Aland CM, Kim HC, et al. Long term follow-up of arthroscopic synovectomy for chronic hemophilic synovitis. Arthroscopy. 1987;3:231–236.
  • Eickhoff HH, Koch W, Raderschadt G, et al. Arthroscopy for chronic hemophilic synovitis of the knee. Clin Orthop Relat Res. 1997;343:58–62.
  • Verma N, Valentino LA, Chawla A. Arthroscopic synovectomy in haemophilia: indications, technique and results. Haemophilia. 2007;13(Suppl 3):38–44.
  • Rodriguez-Merchan EC. Haemophilic synovitis of the elbow: radiosynovectomy, open synovectomy or arthroscopic synovectomy?. Thromb Res. 2013;132:15–18.
  • Rodriguez-Merchan EC, Galindo E, Magallon M, et al. Resection of the radial head and partial open synovectomy of the elbow in the young adult with haemophilia: long-term results. Haemophilia. 1995;1:262–266.
  • Silva M, Luck JV Jr. Radial head excision and synovectomy in patients with hemophilia. J Bone Joint Surg Am. 2007;89:2156–2162.
  • Rodriguez-Merchan EC, Jimenez-Yuste V. The role of selective angiographic embolization of the musculo-skeletal system in haemophilia. Haemophilia. 2009;15:864–868.
  • Galli E, Baques A, Moretti N, et al. Hemophilic chronic synovitis: therapy of hemarthrosis using endovascular embolization of knee and elbow arteries. Cardiovasc Intervent Radiol. 2013;36:964–969.

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