1,275
Views
44
CrossRef citations to date
0
Altmetric
Original Articles

Gold nanoparticles synthesized using Panax ginseng leaves suppress inflammatory - mediators production via blockade of NF-κB activation in macrophages

, , , , , & show all
Pages 270-276 | Received 29 Jun 2016, Accepted 22 Aug 2016, Published online: 09 Sep 2016

References

  • Ahn S, Siddiqi MH, Aceituno VC, Simu SY, Yang DC. 2016. Suppression of MAPKs/NF-κB activation induces intestinal anti-inflammatory action of Ginsenoside Rf in HT-29 and RAW 264. 7 cells. Immunol Invest. 45:439–449.
  • Ahn S, Siddiqi MH, Aceituno VC, Simu SY, Zhang J, Perez ZEJ, Kim Y, et al. 2016. Ginsenoside Rg5: Rk1 attenuates TNF-α/IFN-γ-induced production of thymus-and activation-regulated chemokine (TARC/CCL17) and LPS-induced NO production via downregulation of NF-κB/p38 MAPK/STAT1 signaling in human keratinocytes and macrophages. In Vitro Cell Dev Biol Anim. 52:287–295.
  • Ahn S, Siddiqi MH, Noh H, Kim Y, Kim Y, Jin C, et al. 2015. Anti-inflammatory activity of ginsenosides in LPS-stimulated RAW 264.7 cells. Sci Bull. 60:773–784.
  • Bancos S, Stevens DL, Tyner KM. 2014. Effect of silica and gold nanoparticles on macrophage proliferation, activation markers, cytokine production, and phagocytosis in vitro. Int J Nanomed. 10:183–206.
  • Bhadra MP, Sreedhar B, Patra CR. 2014. Potential theranostics application of bio-synthesized silver nanoparticles (4-in-1 system). Theranostics. 4:316–335.
  • Bjarnason I, Hayllar J, MacPherson AJ, Russell AS. 1993. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology. 104:1832–1847.
  • Boisselier E, Astruc D. 2009. Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity. Chem Soc Rev. 38:1759–1782.
  • Chandran SP, Chaudhary M, Pasricha R, Ahmad A, Sastry M. 2006. Synthesis of gold nanotriangles and silver nanoparticles using Aloevera plant extract. Biotechnol Prog. 22:577–583.
  • Choi E, Hwang J. 2004. Effects of methanolic extract and fractions from Litsea cubeba bark on the production of inflammatory mediators in RAW 264.7 cells. Fitoterapia. 75:141–148.
  • Chuang S, Lin C, A Aljuffali I, Fang J. 2016. Specific targeting of engineered nanoparticles to activated macrophages. Curr Nanosci. 12:63–69.
  • Feng D, Zhou Y, Xia M, Ma J. 2011. Folic acid inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 macrophages by suppressing MAPKs and NF-κB activation. Inflamm Res. 60:817–822.
  • Hwang SJ, Jun SH, Park Y, Cha S, Yoon M, Cho S, et al. 2015. Green synthesis of gold nanoparticles using chlorogenic acid and their enhanced performance for inflammation. Nanomedicine. 11:1677–1688.
  • Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, et al. 2016. Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease. Inflamm Res. 65:245–260.
  • Jeong JB, Jeong HJ. 2010. Rheosmin, a naturally occurring phenolic compound inhibits LPS-induced iNOS and COX-2 expression in RAW 264.7 cells by blocking NF-kappaB activation pathway. Food Chem Toxicol.48:2148–2153.
  • Jung C, Seog H, Choi I, Choi H, Cho H. 2005. Effects of wild ginseng (Panax ginseng CA Meyer) leaves on lipid peroxidation levels and antioxidant enzyme activities in streptozotocin diabetic rats. J Ethnopharmacol. 98:245–250.
  • Kang S, Min H. 2012. Ginseng, the ‘Immunity Boost’: The Effects of Panax ginseng on Immune System. J Ginseng Res. 36:354–368.
  • Kim Y, Zhang D, Yang D. 2015. Biosynthesis and biotechnological production of ginsenosides. Biotechnol Adv. 33:717–735.
  • Lee JH, Cho SH. 2011. Korean red ginseng extract ameliorates skin lesions in NC/Nga mice: an atopic dermatitis model. J Ethnopharmacol. 133:810–817.
  • Lee K, Jung SY, Choi S, Yang EJ. 2012. Effects of ginsenoside Re on LPS-induced inflammatory mediators in BV2 microglial cells. BMC Complement Altern Med. 12:196.
  • Liu Z, Li W, Wang F, Sun C, Wang L, Wang J, et al. 2012. Enhancement of lipopolysaccharide-induced nitric oxide and interleukin-6 production by PEGylated gold nanoparticles in RAW 264.7 cells. Nanoscale. 4:7135–7142.
  • Ma JS, Kim WJ, Kim JJ, Kim TJ, Ye SK, Song MD, et al. 2010. Gold nanoparticles attenuate LPS-induced NO production through the inhibition of NF-kappaB and IFN-beta/STAT1 pathways in RAW 264.7 cells. Nitric Oxide. 23:214–219.
  • Naz F, Koul V, Srivastava A, Gupta YK, Dinda AK. 2016. Biokinetics of ultrafine gold nanoparticles (AuNPs) relating to redistribution and urinary excretion: a long-term in vivo study. J Drug Target. 24:720–729.
  • Norouz Dizaji A, Yilmaz M, Piskin E. 2016. Silver or gold deposition onto magnetite nanoparticles by using plant extracts as reducing and stabilizing agents. Artifi Cells, Nanomed Biotechnol. 44:1109–1115.
  • Oh S, Lee S, Choi W, Lim C. 2014. Skin anti-photoaging properties of ginsenoside Rh2 epimers in UV-B-irradiated human keratinocyte cells. J Biosci. 39:673–682.
  • Piper JM, Ray WA, Daugherty JR, Griffin MR. 1991. Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs. Ann Intern Med. 114:735–740.
  • Qi X, Teng Y, Yoon Y, Kim D, Cai D, Lee K. 2011. Reactive oxygen species are involved in the IFN‐γ‐stimulated production of Th2 chemokines in HaCaT keratinocytes. J Cell Physiol. 226:58–65.
  • Rehman MU, Yoshihisa Y, Miyamoto Y, Shimizu T. 2012. The anti-inflammatory effects of platinum nanoparticles on the lipopolysaccharide-induced inflammatory response in RAW 264.7 macrophages. Inflamm. Res. 61:1177–1185.
  • Saito H, Morita M, Takagi K. 1973. Pharmacological studies of Panax ginseng leaves. Jpn J Pharmacol. 23:43–56.
  • Shan J, Fu J, Zhao Z, Kong X, Huang H, Luo L, et al. 2009. Chlorogenic acid inhibits lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells through suppressing NF-kappaB and JNK/AP-1 activation. Int Immunopharmacol. 9:1042–1048.
  • Siddiqi MH, Siddiqi MZ, Kang S, Noh HY, Ahn S, Simu SY, et al. 2015. Inhibition of osteoclast differentiation by ginsenoside Rg3 in RAW 264. 7 cells via RANKL, JNK and p38 MAPK pathways through a modulation of cathepsin K: An in silico and in vitro study. Phytother Res. 29:1286–1294.
  • Siddiqi MH, Siddiqi MZ, Ahn S, Kang S, Kim Y, Sathishkumar N, et al. 2013. Ginseng saponins and the treatment of osteoporosis: mini literature review. J Ginseng Res. 37:261–268.
  • Singh P, Kim YJ, Wang C, Mathiyalagan R, El-Agamy Farh M, Yang DC. 2016. Biogenic silver and gold nanoparticles synthesized using red ginseng root extract, and their applications. Artifi Cells Nanomed Biotechnol. 44:811–816.
  • Singh P, Kim YJ, Yang DC. 2015. A strategic approach for rapid synthesis of gold and silver nanoparticles by Panax ginseng leaves. Artifi Cells Nanomed Biotechnol. 1–9.
  • Su Y, Chiou W, Chao S, Lee M, Chen C, Tsai Y. 2011. Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways. Int Immunopharmacol. 11:1166–1172.
  • Szelenyi I. 2012. Nanomedicine: evolutionary and revolutionary developments in the treatment of certain inflammatory diseases. Inflamm Res.61:1–9.
  • Tomita Y, Rikimaru-Kaneko A, Hashiguchi K, Shirotake S. 2011. Effect of anionic and cationic n-butylcyanoacrylate nanoparticles on NO and cytokine production in Raw 264. 7 cells. Immunopharmacol Immunotoxicol. 33:730–737.
  • Wang H, Peng D, Xie J. 2009. Ginseng leaf-stem: bioactive constituents and pharmacological functions. Chinese Med. 4:20.
  • Wang T, Wu F, Jin Z, Zhai Z, Wang Y, Tu B, et al. 2014. Plumbagin inhibits LPS-induced inflammation through the inactivation of the nuclear factor-kappa B and mitogen activated protein kinase signaling pathways in RAW 264.7 cells. Food Chem Toxicol. 64:177–183.
  • Wu CF, Bi XL, Yang JY, Zhan JY, Dong YX, Wang JH, et al. 2007. Differential effects of ginsenosides on NO and TNF-alpha production by LPS-activated N9 microglia. Int Immunopharmacol. 7:313–320.
  • Zheng H, Jeong Y, Song J, Ji GE. 2011. Oral administration of ginsenoside Rh1 inhibits the development of atopic dermatitis-like skin lesions induced by oxazolone in hairless mice. Int Immunopharmacol. 11:511–518.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.