MiR-199a targeting ROCK1 to affect kidney cell proliferation, invasion and apoptosis

References

• YuCai B, Xu H, Xu Z, et al. Expressions of stem cell transcription factors Nanog and Oct4 in renal cell carcinoma tissues and clinical significance. Artif Cells Nanomed Biotechnol. 2016;44:1818–1823.
   PubMed Web of Science ®Google Scholar
• Bukowski RM. Cytokine therapy for metastatic renal cell carcinoma. Semin Urol Oncol. 2001;19:148–154.
   PubMedGoogle Scholar
• Motzer RJ, Bukowski RM. Targeted therapy for metastatic renal cell carcinoma. J Clin Oncol. 2006;24:5601–5608.
   PubMed Web of Science ®Google Scholar
• Motzer RJ, Molina AM. Targeting renal cell carcinoma. J Clin Oncol. 2009;27:3274–3276.
   PubMed Web of Science ®Google Scholar
• Wang M, Xie R, Si H, et al. Integrated bioinformatics analysis of miRNA expression in osteosarcoma. Artif Cells Nanomed Biotechnol. 2017;45:936–943.
   PubMed Web of Science ®Google Scholar
• Liu Y, Han L, Bai Y, et al. Down-regulation of microRNA-133 predicts poor overall survival and regulates the growth and invasive abilities in glioma. Artif Cells Nanomed Biotechnol. 2017 [Apr 4];[1–5]. doi: 10.1080/21691401.2017.1304551
   Web of Science ®Google Scholar
• Palmero EI, de Campos SG, Campos M, et al. Mechanisms and role of microRNA deregulation in cancer onset and progression. Genet Mol Biol. 2011;34:363–370.
   PubMed Web of Science ®Google Scholar
• Wang B, Teng Y, Liu Q. MicroRNA-153 regulates NRF2 expression and is associated with breast carcinogenesis. Clin Lab. 2016;62:39–47.
   PubMed Web of Science ®Google Scholar
• Xu X, Zhang Y, Jasper J, et al. MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer. Oncotarget. 2016;7:20381–20394.
   PubMed Web of Science ®Google Scholar
• Yin K, Yin W, Wang Y, et al. MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-beta signaling in estrogen receptor positive breast cancer cells. Oncotarget. 2016;7:24537–22448.
   PubMedGoogle Scholar
• Andolfo I, Liguori L, De AP, et al. The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma. Neuro Oncol. 2012;14:596–612.
   PubMed Web of Science ®Google Scholar
• Si T, Liu C, Xu K, et al. Association of miR-199a expression with clinicopathologic characteristics and prognosis of renal cell carcinoma. J Southern Med Univ. 2012;32:1568–1571.
   Google Scholar
• Pearce LR, Komander D, Alessi DR. The nuts and bolts of AGC protein kinases. Nat Rev Mol Cell Biol. 2010;11:9–22.
   PubMed Web of Science ®Google Scholar
• Tsai NP, Wei LN. RhoA/ROCK1 signaling regulates stress granule formation and apoptosis. Cell Signal. 2010;22:668–675.
   PubMed Web of Science ®Google Scholar
• BillimOugolkov V, Yuuki A, Naito K, et al. Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma. Br J Cancer. 2009;101:2005–2014.
   PubMed Web of Science ®Google Scholar
• Ougolkov AV, Bone ND, Fernandez-Zapico ME, et al. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor-kappa B target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood. 2007;110:735–742.
   PubMed Web of Science ®Google Scholar
• Juan D, Alexe G, Antes T, et al. Identification of a MicroRNA panel for clear-cell kidney cancer. Urology. 2010;75:835–841.
   PubMed Web of Science ®Google Scholar
• Liu H, Brannon A, Reddy A, et al. Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell renal cell carcinoma. BMC Syst Biol. 2010;4:51–67.
   PubMed Web of Science ®Google Scholar
• Fang C, Zhao Y, Guo B. MiR-199b-5p targets HER2 in breast cancer cells. J Cell Biochem. 2013;114:1457–1463.
   PubMed Web of Science ®Google Scholar
• WuZhang S, Li G, Chen P, et al. miR-198 targets SHMT1 to inhibit cell proliferation and enhance cell apoptosis in lung adenocarcinoma. Tumor Biol. 2016;4:5193–5202.
   Google Scholar
• Wang M, Wang J, Kong X, et al. MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8. Sci Rep. 2014;4:6145.
   PubMed Web of Science ®Google Scholar
• Tan S, Li R, Ding K, et al. miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway. FEBS Lett. 2011;585:2229–2234.
   PubMed Web of Science ®Google Scholar
• Zheng B, Liang L, Wang C, et al. MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancer. Clin Cancer Res. 2011;17:7574–7583.
   PubMed Web of Science ®Google Scholar
• Majid S, Dar AA, Saini S, et al. MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer. PLoS One. 2012;7:e46743.
   PubMed Web of Science ®Google Scholar