Differentiation of conjunctiva mesenchymal stem cells into secreting islet beta cells on plasma treated electrospun nanofibrous scaffold

References

• Gan MJ, Albanese-O'Neill A, Haller MJ. Type 1 diabetes: current concepts in epidemiology, pathophysiology, clinical care, and research. Curr Probl Pediatr Adolesc Health Care. 2012;42:269–291.
   PubMed Web of Science ®Google Scholar
• Kar P, Holt RI. The effect of sulphonylureas on the microvascular and macrovascular complications of diabetes. Cardiovasc Drugs Ther. 2008;22:207–213.
   PubMed Web of Science ®Google Scholar
• Amer LD, Mahoney MJ, Bryant SJ. Tissue engineering approaches to cell-based type 1 diabetes therapy. Tissue Eng Part B Rev. 2014;20:455–467.
   PubMed Web of Science ®Google Scholar
• Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230–238.
   PubMed Web of Science ®Google Scholar
• Bonner-Weir S, Taneja M, Weir GC, et al. In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci USA. 2000;97:7999–8004.
   PubMed Web of Science ®Google Scholar
• Zulewski H, Abraham EJ, Gerlach MJ, et al. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes. 2001;50:521–533.
   PubMed Web of Science ®Google Scholar
• Phadnis SM, Joglekar MV, Dalvi MP, et al. Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo. Cytotherapy. 2011;13:279–293.
   PubMed Web of Science ®Google Scholar
• Timper K, Seboek D, Eberhardt M, et al. Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem Biophys Res Commun. 2006;341:1135–1140.
   PubMed Web of Science ®Google Scholar
• Chen LB, Jiang XB, Yang L. Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cells. World J Gastroenterol. 2004;10:3016–3020.
   PubMed Web of Science ®Google Scholar
• Aloysious N, Nair PD. Enhanced survival and function of islet-like clusters differentiated from adipose stem cells on a three-dimensional natural polymeric scaffold: an in vitro study. Tissue Eng Part A. 2014;20:1508–1522.
   PubMed Web of Science ®Google Scholar
• Bosco D, Meda P, Halban PA, et al. Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin. Diabetes. 2000;49:233–243.
   PubMed Web of Science ®Google Scholar
• Stendahl JC, Kaufman DB, Stupp SI. Extracellular matrix in pancreatic islets: relevance to scaffold design and transplantation. Cell Transplant. 2009;18:1–12.
   PubMed Web of Science ®Google Scholar
• Takeuchi H, Nakatsuji N, Suemori H. Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture. Sci Rep. 2014;4:4488.
   PubMed Web of Science ®Google Scholar
• Grayson WL, Ma T, Bunnell B. Human mesenchymal stem cells tissue development in 3D PET matrices. Biotechnol Prog. 2004;20:905–912.
   PubMed Web of Science ®Google Scholar
• Nadri S, Kazemi B, Eslaminejad MB, et al. High yield of cells committed to the photoreceptor-like cells from conjunctiva mesenchymal stem cells on nanofibrous scaffolds. Mol Biol Rep. 2013;40:3883–3890.
   PubMed Web of Science ®Google Scholar
• Nadri S, Soleimani M, Kiani J, et al. Multipotent mesenchymal stem cells from adult human eye conjunctiva stromal cells. Differentiation. 2008;76:223–231.
   PubMed Web of Science ®Google Scholar
• Nadri S, Nasehi F, Barati G. Effect of parameters on the quality of core-shell fibrous scaffold for retinal differentiation of conjunctiva mesenchymal stem cells. J Biomed Mater Res A. 2017;105:189–197.
   PubMed Web of Science ®Google Scholar
• van der Windt DJ, Bottino R, Kumar G, et al. Clinical islet xenotransplantation: how close are we? Diabetes. 2012;61:3046–3055.
   PubMed Web of Science ®Google Scholar
• Ryan EA, Lakey JR, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes. 2001;50:710–719.
   PubMed Web of Science ®Google Scholar
• Massumi M, Hoveizi E, Baktash P, et al. Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells. Exp Cell Res. 2014;322:51–61.
   PubMed Web of Science ®Google Scholar
• Chandra V, Swetha G, Muthyala S, et al. Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice. PLoS One. 2011;6:e20615.
   PubMed Web of Science ®Google Scholar
• Bai C, Gao Y, Li Q, et al. Differentiation of chicken umbilical cord mesenchymal stem cells into beta-like pancreatic islet cells. Artif Cells Nanomed Biotechnol. 2015;43:106–111.
   PubMed Web of Science ®Google Scholar
• Habener JF, Kemp DM, Thomas MK. Minireview: transcriptional regulation in pancreatic development. Endocrinology. 2005; 146:1025–1034.
   PubMed Web of Science ®Google Scholar
• Suarez-Pinzon WL, Lakey JR, Brand SJ, et al. Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass. J Clin Endocrinol Metab. 2005;90:3401–3409.
   PubMed Web of Science ®Google Scholar
• Hardikar AA, Marcus-Samuels B, Geras-Raaka E, et al. Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates. Proc Natl Acad Sci USA. 2003;100:7117–7122.
   PubMed Web of Science ®Google Scholar
• Florio P, Luisi S, Marchetti P, et al. Activin A stimulates insulin secretion in cultured human pancreatic islets. J Endocrinol Investig. 2000;23:231–234.
   PubMed Web of Science ®Google Scholar
• Brun T, Franklin I, St-Onge L, et al. The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets. J Cell Biol. 2004;167:1123–1135.
   PubMed Web of Science ®Google Scholar
• Liu J, Liu Y, Wang H, et al. Direct differentiation of hepatic stem-like WB cells into insulin-producing cells using small molecules. Sci Rep. 2013;3:1185.
   PubMed Web of Science ®Google Scholar
• Park MK, Han C, Lee KH, et al. Effects of activin A on pancreatic ductal cells in streptozotocin-induced diabetic rats. Transplantation. 2007;83:925–930.
   PubMed Web of Science ®Google Scholar
• Zalzman M, Anker-Kitai L, Efrat S. Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype. Diabetes. 2005;54:2568–2575.
   PubMed Web of Science ®Google Scholar
• Sun Y, Chen L, Hou XG, et al. Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro. Chin Med J (Engl). 2007;120:771–776.
   PubMed Web of Science ®Google Scholar
• Brewer GJ, Torricelli JR, Evege EK, et al. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res. 1993;35:567–576.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Dou Z. Under a nonadherent state, bone marrow mesenchymal stem cells can be efficiently induced into functional islet-like cell clusters to normalize hyperglycemia in mice: a control study. Stem Cell Res Ther. 2014;5:66.
   PubMed Web of Science ®Google Scholar
• Lehmann R, Zuellig RA, Kugelmeier P, et al. Superiority of small islets in human islet transplantation. Diabetes. 2007;56:594–603.
   PubMed Web of Science ®Google Scholar
• D'Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol. 2006;24:1392–1401.
   PubMed Web of Science ®Google Scholar
• Johnson JD, Ahmed NT, Luciani DS, et al. Increased islet apoptosis in Pdx1+/- mice. J Clin Investig. 2003;111:1147–1160.
   PubMed Web of Science ®Google Scholar
• Zhao FQ, Keating AF. Functional properties and genomics of glucose transporters. Curr Genomics. 2007;8:113–128.
   PubMed Web of Science ®Google Scholar
• Guillam MT, Hummler E, Schaerer E, et al. Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2. Nat Genet. 1997;17:327–330.
   PubMed Web of Science ®Google Scholar
• Tang DQ, Cao LZ, Burkhardt BR, et al. In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow. Diabetes. 2004;53:1721–1732.
   PubMed Web of Science ®Google Scholar
• Nadri S, Yazdani S. Isolation and expansion of mesenchymal stem cells from human conjunctival tissue. Curr Protocols Stem Cell Biol. 2015;33:1F.14.1–8.
   Google Scholar
• Sonksen P, Sonksen J. Insulin: understanding its action in health and disease. Br J Anaesth. 2000;85:69–79.
   PubMed Web of Science ®Google Scholar
• Mooranian A, Negrulj R, Takechi R, et al. Electrokinetic potential-stabilization by bile acid-microencapsulating formulation of pancreatic beta-cells cultured in high ratio poly-L-ornithine-gel hydrogel colloidal dispersion: applications in cell-biomaterials, tissue engineering and biotechnological applications. Artif Cells Nanomed Biotechnol. 2017. DOI:https://doi.org/10.1080/21691401.2017.1362416
   Google Scholar
• Weber LM, Hayda KN, Anseth KS. Cell-matrix interactions improve beta-cell survival and insulin secretion in three-dimensional culture. Tissue Eng Part A. 2008;14:1959–1968.
   PubMed Web of Science ®Google Scholar
• Cheng JY, Raghunath M, Whitelock J, et al. Matrix components and scaffolds for sustained islet function. Tissue Eng Part B Rev. 2011;17:235–247.
   PubMed Web of Science ®Google Scholar
• Brissova M, Fowler MJ, Nicholson WE, et al. Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem. 2005;53:1087–1097.
   PubMed Web of Science ®Google Scholar
• Daoud J, Petropavlovskaia M, Rosenberg L, et al. The effect of extracellular matrix components on the preservation of human islet function in vitro. Biomaterials. 2010;31:1676–1682.
   PubMed Web of Science ®Google Scholar
• Kaur S, Ma Z, Gopal R, et al. Plasma-induced graft copolymerization of poly(methacrylic acid) on electrospun poly(vinylidene fluoride) nanofiber membrane. Langmuir ACS J Surf Colloids. 2007;23:13085–13092.
   PubMed Web of Science ®Google Scholar
• Rupp F, Scheideler L, Olshanska N, et al. Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces. J Biomed Mater Res A. 2006;76:323–334.
   PubMed Web of Science ®Google Scholar
• Bhang SH, Lim JS, Choi CY, et al. The behavior of neural stem cells on biodegradable synthetic polymers. J Biomater Sci Polymer Ed. 2007;18:223–239.
   PubMed Web of Science ®Google Scholar