References
- Blüml S, Redlich K, Smolen JS. Mechanisms of tissue damage in arthritis. Semin Immunopathol. 2014;36:531–540.
- Alghasham A, Rasheed Z. Therapeutic targets for rheumatoid arthritis: progress and promises. Autoimmunity. 2014;47:77–94.
- Thalhamer T, McGrath MA, Harnett MM. MAPKs and their relevance to arthritis and inflammation. Rheumatology (Oxford). 2008;47:409–414.
- Thummuri D, Jeengar MK, Shrivastava S, et al. Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK signalling. Pharmacol Res. 2015;99:63–73.
- Laveti D, Kumar M, Hemalatha R, et al. Anti-inflammatory treatments for chronic diseases: a review. IADT. 2013;12:349–361.
- Lefevre S, Meier FM, Neumann E, et al. Role of synovial fibroblasts in rheumatoid arthritis. Curr Pharm Des. 2015;21:130–141.
- Choi YJ, Lee WS, Lee EG, et al. Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2. Inflammation. 2014;37:1496–1503.
- Yoon HY, Lee EG, Lee H, et al. Kaempferol inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of COX-2, PGE2 and MMPs. Int J Mol Med. 2013;32:971–977.
- Goldring MB, Berenbaum F. The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide. Clin Orthop Relat Res. 2004;427:S37–S46.
- Dyawanapelly S, Ghodke SB, Vishwanathan R, et al. RNA interference-based therapeutics: molecular platforms for infectious diseases. J Biomed Nanotechnol. 2014;10:1998–2037.
- Baigude H, Rana TM. Strategies to antagonize miRNA functions in vitro and in vivo. Nanomedicine (Lond). 2014;9:2545–2555.
- Leech MT, Morand EF. Fibroblasts and synovial immunity. Curr Opin Pharmacol. 2013;13:565–569.
- Dimitroulas T, Nikas SN, Trontzas P, et al. Biologic therapies and systemic bone loss in rheumatoid arthritis. Autoimmun Rev. 2013;12:958–966.
- Filer A. The fibroblast as a therapeutic target in rheumatoid arthritis. Curr Opin Pharmacol. 2013;13:413–419.
- Semerano L, Clavel G, Assier E, et al. Blood vessels, a potential therapeutic target in rheumatoid arthritis? Joint Bone Spine. 2011;78:118–123.
- Lee AS, Ellman MB, Yan D, et al. A current review of molecular mechanisms regarding osteoarthritis and pain. Gene. 2013;527:440–447.
- Li J, Shao X, Wu L, et al. Honokiol: an effective inhibitor of tumor necrosis factor-alpha-induced up-regulation of inflammatory cytokine and chemokine production in human synovial fibroblasts. Acta Biochim Biophys Sin (Shanghai). 2011;43:380–386.
- Mollaie HR, Monavari SH, Arabzadeh SA, et al. RNAi and miRNA in viral infections and cancers. Asian Pac J Cancer Prev. 2013;14:7045–7056.
- Wang ZH, Yang ZQ, He XJ, et al. Lentivirus-mediated knockdown of aggrecanase-1 and -2 promotes chondrocyte-engineered cartilage formation in vitro. Biotechnol Bioeng. 2010;107:730–736.
- Siebert S, Tsoukas A, Robertson J, et al. Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacol Rev. 2015;67:280–309.
- Selmi C, Generali E, Massarotti M, et al. New treatments for inflammatory rheumatic disease. Immunol Res. 2014;60:277–288.
- Moon SJ, Park MK, Oh HJ, et al. Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts. Korean J Intern Med. 2010;25:429–435.
- Nanau RM, Neuman MG. Safety of anti-tumor necrosis factor therapies in arthritis patients. J Pharm Pharm Sci. 2014;17:324–361.
- Lie PP, Cheng CY, Mruk DD. The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics. Cell Mol Life Sci. 2012;69:487–500.
- Yoon JS, Lee HJ, Choi SH, et al. Quercetin inhibits IL-1beta-induced inflammation, hyaluronan production and adipogenesis in orbital fibroblasts from Graves' orbitopathy. PLoS One. 2011;6:e26261.