Riboflavin immobilized Fe₃O₄ magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents

References

• Saini RK, Chouhan R, Bagri LP, et al. Strategies of targeting tumors and cancers. J Can Res Updates. 2012;1:129–152.
   Google Scholar
• Kalli KR, Oberg AL, Keeney GL, et al. Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol. 2008;108:619–626.
   PubMed Web of Science ®Google Scholar
• Pillai MR, Chacko P, Kesari LA, et al. Expression of folate receptors and heterogeneous nuclear ribonucleoprotein E1 in women with human papillomavirus mediated transformation of cervical tissue to cancer. J Clin Pathol. 2003;56:569–574.
   PubMed Web of Science ®Google Scholar
• Leone JP, Bhargava R, Theisen BK, et al. Expression of high affinity folate receptor in breast cancer brain metastasis. Oncotarget. 2015;6:30327–30333.
   PubMedGoogle Scholar
• Shi H, Guo J, Li C, et al. A current review of folate receptor alpha as a potential tumor target in non-small-cell lung cancer. Drug Des Dev Ther. 2015;9:4989–4996.
   PubMed Web of Science ®Google Scholar
• Weitman SD, Lark RH, Coney LR, et al. Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues. Cancer Res. 1992;52:3396–3401.
   PubMed Web of Science ®Google Scholar
• Yang SJ, Lin FH, Tsai KC, et al. Acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells. Bioconjugate Chem. 2010;21:679–689.
   PubMed Web of Science ®Google Scholar
• Guo J, Schlich M, Cryan JF, et al. Targeted drug delivery via folate receptors for the treatment of brain cancer: can the promise deliver? J Pharm Sci. 2017;106:3413–3420.
   PubMed Web of Science ®Google Scholar
• Lee RJ, Low PS. Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro. Biochim Biophys Acta. 1995;1233:134–144.
   PubMed Web of Science ®Google Scholar
• Lee JY, Termsarasab U, Park JH, et al. Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery. J Control Release. 2016;236:38–46.
   PubMed Web of Science ®Google Scholar
• Sega EI, Low PS. Tumor detection using folate receptor-targeted imaging agents. Cancer Metastasis Rev. 2008;27:655–664.
   PubMed Web of Science ®Google Scholar
• Bhunia SK, Maity AR, Nandi S, et al. Imaging cancer cells expressing the folate receptor with carbon dots produced from folic acid. Chembiochem. 2016;17:614–619.
   PubMed Web of Science ®Google Scholar
• Ocak M, Gillman AG, Bresee J, et al. Folate receptor-targeted multimodality imaging of ovarian cancer in a novel syngeneic mouse model. Mol Pharmaceutics. 2015;12:542–553.
   PubMed Web of Science ®Google Scholar
• Zwicke GL, Mansoori GA, Jeffery CJ. Utilizing the folate receptor for active targeting of cancer nanotherapeutics. Nano Rev. 2012;3:18496. doi:10.3402/nano.v3i0.18496.
   Google Scholar
• Warburg O, Wind F, Negelein E. The metabolism of tumors in the body. J Gen Physiol. 1927;8:519–530.
   PubMedGoogle Scholar
• Warburg O. On the origin of cancer cells. Science. 1956;123:309–314.
   PubMed Web of Science ®Google Scholar
• Altenberg B, Greulich KO. Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics. 2004;84:1014–1020.
   PubMed Web of Science ®Google Scholar
• Seymour GJ, Walsh MD, Lavin MF, et al. Transferrin receptor expression by human bladder transitional cell carcinomas. Urol Res. 1987;15:341–344.
   PubMed Web of Science ®Google Scholar
• Walker RA, Day SJ. Transferrin receptor expression in nonmalignant and malignant human breast tissue. J Pathol. 1986;148:217–224.
   PubMed Web of Science ®Google Scholar
• Kondo K, Noguchi M, Mukai K, et al. Transferrin receptor expression in adenocarcinoma of the lung as a histopathologic indicator of prognosis. Chest. 1990;97:1367–1371.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Xiang J, Liu Y, et al. Constructing transferrin receptor targeted drug delivery system by using doxorubicin hydrochloride and vanadocene dichloride. Bioorg Med Chem Lett. 2011;21:5982–5986.
   PubMed Web of Science ®Google Scholar
• Bareford LM, Phelps MA, Foraker AB, et al. Intracellular processing of riboflavin in human breast cancer cells. Mol Pharmaceutics. 2008;5:839–848.
   PubMed Web of Science ®Google Scholar
• Johnson T, Ouhtit A, Gaur R, et al. Biochemical characterization of riboflavin carrier protein (RCP) in prostate cancer. Front Biosci. 2009;14:3634–3640.
   Web of Science ®Google Scholar
• Rao PN, Crippin J, Levine E, et al. Elevation of serum riboflavin carrier protein in hepatocellular carcinoma. Hepatol Res. 2006;35:83–87.
   PubMed Web of Science ®Google Scholar
• Riboflavin. Monograph. Altern Med Rev. 2008;13:334–340.
   PubMedGoogle Scholar
• Thomas TP, Choi SK, Li MH, et al. Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery. Bioorg Med Chem. 2010;20:5191–5194.
   Web of Science ®Google Scholar
• Guo D, Shi C, Wang X, et al. Riboflavin-containing telodendrimer nanocarriers for efficient doxorubicin delivery: high loading capacity, increased stability, and improved anticancer efficacy. Biomaterials. 2017;141:161–175.
   PubMed Web of Science ®Google Scholar
• Singh S, Mehra NK, Jain NK. Development and characterization of the paclitaxel loaded riboflavin and thiamine conjugated carbon nanotubes for cancer treatment. Pharm Res. 2016;33:1769–1781.
   PubMed Web of Science ®Google Scholar
• Huang MY, Shang EX, Tang YP, et al. Research on nourishing and tonifying blood effects of the herb pair consisting of Angelica sinensis and Ligusticum chuanxiong on the basis of drug interaction. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013;33:516–521.
   PubMedGoogle Scholar
• Chao WW, Lin BF. Bioactivities of major constituents isolated from Angelica sinensis (Danggui). Chin Med. 2011;6:29
   PubMed Web of Science ®Google Scholar
• Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause. 2002;9:145–150.
   PubMed Web of Science ®Google Scholar
• Jayapaul J, Arns S, Lederle W, et al. Riboflavin carrier protein-targeted fluorescent USPIO for the assessment of vascular metabolism in tumors. Biomaterials. 2012;33:8822–8829.
   PubMed Web of Science ®Google Scholar
• Jayapaul J, Arns S, Bunker M, et al. In vivo evaluation of riboflavin receptor targeted fluorescent USPIO in mice with prostate cancer xenografts. Nano Res. 2016;9:1319–1333.
   PubMed Web of Science ®Google Scholar
• Witte AB, Leistra AN, Wong PT, et al. Atomic force microscopy probing of receptor − nanoparticle interactions for riboflavin receptor targeted gold − dendrimer nanocomposites. J Phys Chem B. 2014;118:2872–2882.
   PubMed Web of Science ®Google Scholar
• Sau A, Sanyal S, Bera K, et al. DNA damage and apoptosis induction in cancer cells by chemically engineered thiolated riboflavin gold nanoassembly. ACS Appl Mater Interfaces. 2018;10:4582–4589.
   PubMed Web of Science ®Google Scholar
• Beztsinna N, Tsvetkova Y, Bartneck M, et al. Amphiphilic phospholipid-based riboflavin derivatives for tumor targeting nanomedicines. Bioconjugate Chem. 2016;27:2048–2061.
   PubMed Web of Science ®Google Scholar
• Chiu SC, Chen SP, Huang SY, et al. Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide. PLoS One. 2012;7:e33742.
   PubMed Web of Science ®Google Scholar
• Liu PY, Sheu JJ, Lin PC, et al. Expression of Nur77 induced by an n-butylidenephthalide derivative promotes apoptosis and inhibits cell growth in oral squamous cell carcinoma. Invest New Drugs. 2012;30:79–89.
   PubMed Web of Science ®Google Scholar
• Wei CW, Lin CC, Yu YL, et al. n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2alpha and telomerase activity. Acta Pharmacol Sin. 2009;30:1297–1306.
   PubMed Web of Science ®Google Scholar
• Chen YL, Jian MH, Lin CC, et al. The induction of orphan nuclear receptor Nur77 expression by n-butylenephthalide as pharmaceuticals on hepatocellular carcinoma cell therapy. Mol Pharmacol. 2008;74:1046–1058.
   PubMed Web of Science ®Google Scholar
• Lin PC, Chen YL, Chiu SC, et al. Orphan nuclear receptor, Nurr-77 was a possible target gene of butylidenephthalide chemotherapy on glioblastoma multiform brain tumor. J Neurochem. 2008;106:1017–1026.
   PubMed Web of Science ®Google Scholar
• Siddiqui M, Rajkumar SV. The high cost of cancer drugs and what we can do about it. Mayo Clin Proc. 2012;87:935–943.
   PubMed Web of Science ®Google Scholar
• Huang J, Li Y, Orza A, et al. Magnetic nanoparticle facilitated drug delivery for cancer therapy with targeted and image‐guided approaches. Adv Funct Mater. 2016;26:3818–3836.
   PubMed Web of Science ®Google Scholar
• Wu C-Y, Wu M-L, Chen Y-C. Selective extraction of n-butylidenephthalide from Angelica sinensis (Danggui) by using functionalized iron oxide magnetic nanoparticles as trapping probes. Anal Methods. 2018;10:1593–1601.
   Web of Science ®Google Scholar
• Chen W-Y, Chen Y-C. Functional Fe3O4@ZnO magnetic nanoparticle-assisted enrichment and enzymatic digestion of phosphoproteins from saliva. Anal Bioanal Chem. 2010;398:2049–2057.
   PubMed Web of Science ®Google Scholar
• Chen W-Y, Chen Y-C. MALDI MS analysis of oligonucleotides: desalting by functional magnetite beads using microwave-assisted extraction. Anal Chem. 2007;79:8061–8066.
   PubMed Web of Science ®Google Scholar
• Cohen I, Tagliaferri M, Tripathy D. Traditional Chinese medicine in the treatment of breast cancer. Semin Oncol. 2002;29:563–574.
   PubMed Web of Science ®Google Scholar
• Gurtu V, Kain SR, Zhang G. Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal Biochem. 1997;251:98–102.
   PubMed Web of Science ®Google Scholar
• Kominsky DJ, Bickel RJ, Tyler KL. Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death. Cell Death Differ. 2002;9:926–933.
   PubMed Web of Science ®Google Scholar