Effect of exposure of osteoblast-like cells to low-dose silver nanoparticles: uptake, retention and osteogenic activity

References

• Derks J, Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol. 2015;42:S158–S171.
   PubMed Web of Science ®Google Scholar
• Chen X, Schluesener HJ. Nanosilver: a nanoproduct in medical application. Toxicol Lett. 2008;176:1–12.
   PubMed Web of Science ®Google Scholar
• Qing Y, Cheng L, Li R, et al. Potential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies. Int J Nanomedicine. 2018;13:3311–3327.
   PubMed Web of Science ®Google Scholar
• Jia Z, Xiu P, Li M, et al. Bioinspired anchoring AgNPs onto micro-nanoporous TiO 2 orthopedic coatings: Trap-killing of bacteria, surface-regulated osteoblast functions and host responses. Biomaterials. 2016;75:203–222.
   PubMed Web of Science ®Google Scholar
• Noronha VT, Paula AJ, Durán G, et al. Silver nanoparticles in dentistry. Dent Mater. 2017;33:1110–1126.
   PubMed Web of Science ®Google Scholar
• Zhao L, Wang H, Huo K, et al. Antibacterial nano-structured titania coating incorporated with silver nanoparticles. Biomaterials. 2011;32:5706–5716.
   PubMed Web of Science ®Google Scholar
• Tao Q, Mahmood M, Zheng Y, et al. A genomic characterization of the influence of silver nanoparticles on bone differentiation in MC3T3‐E1 cells. J Appl Toxicol. 2017;38:172–179.
   PubMed Web of Science ®Google Scholar
• Qin H, Zhu C, An Z, et al. Silver nanoparticles promote osteogenic differentiation of human urine-derived stem cells at noncytotoxic concentrations. Int J Nanomedicine. 2014;9:2469–2478.
   PubMed Web of Science ®Google Scholar
• Mahmood M, Li Z, Casciano D, et al. Nanostructural materials increase mineralization in bone cells and affect gene expression through miRNA regulation. J Cell Mol Med. 2011;15:2297–2306.
   PubMed Web of Science ®Google Scholar
• Pauksch L, Hartmann S, Rohnke M, et al. Biocompatibility of silver nanoparticles and silver ions in primary human mesenchymal stem cells and osteoblasts. Acta Biomater. 2014;10:439–449.
   PubMed Web of Science ®Google Scholar
• Cao H, Zhang W, Meng F, et al. Osteogenesis catalyzed by titanium-supported silver nanoparticles. ACS Appl Mater Interfaces. 2017;9:5149–5157.
   PubMed Web of Science ®Google Scholar
• Zielinska E, Tukaj C, Radomski MW, et al. Molecular mechanism of silver nanoparticles-induced human osteoblast cell death: protective effect of inducible nitric oxide synthase inhibitor. Plos One. 2016;11:e0164137.
   PubMed Web of Science ®Google Scholar
• Rosário F, Hoet P, Santos C, et al. Death and cell cycle progression are differently conditioned by the AgNP size in osteoblast-like cells. Toxicology. 2016;368:103–115.
   PubMed Web of Science ®Google Scholar
• Albers CE, Hofstetter W, Siebenrock KA, et al. In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations. Nanotoxicology. 2013;7:30–36.
   PubMed Web of Science ®Google Scholar
• Sthijns MM, Thongkam W, Albrecht C, et al. Silver nanoparticles induce hormesis in A549 human epithelial cells. Toxicol in Vitro. 2017;40:223–233.
   PubMed Web of Science ®Google Scholar
• Brzóska K, Męczyńska-Wielgosz S, Stępkowski TM, et al. Adaptation of HepG2 cells to silver nanoparticles-induced stress is based on the pro-proliferative and anti-apoptotic changes in gene expression. Mutagenesis. 2015;30:431–439.
   PubMed Web of Science ®Google Scholar
• Tyne W, Little S, Spurgeon DJ, et al. Hormesis depends upon the life-stage and duration of exposure: examples for a pesticide and a nanomaterial. Ecotoxicol Environ Saf. 2015;120:117–123.
   PubMed Web of Science ®Google Scholar
• Vila L, Marcos R, Hernández A. Long-term effects of silver nanoparticles in caco-2 cells. Nanotoxicology. 2017;11:771–780.
   PubMed Web of Science ®Google Scholar
• Choo WH, Park CH, Jung SE, et al. Long-term exposures to low doses of silver nanoparticles enhanced in vitro malignant cell transformation in non-tumorigenic BEAS-2B cells. Toxicol in Vitro. 2016;37:41–49.
   PubMed Web of Science ®Google Scholar
• Herzog F, Clift MJ, Piccapietra F, et al. Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface. Part Fibre Toxicol. 2013;10:11.
   PubMed Web of Science ®Google Scholar
• Powers CM, Badireddy AR, Ryde IT, et al. Silver nanoparticles compromise neurodevelopment in PC12 cells: critical contributions of silver ion, particle size, coating, and composition. Environ Health Perspect. 2011;119:37–44.
   PubMed Web of Science ®Google Scholar
• You F, Tang W, Yung LL. Real-time monitoring of the Trojan-horse effect of silver nanoparticles by using a genetically encoded fluorescent cell sensor. Nanoscale. 2018;10:7726–7735.
   PubMed Web of Science ®Google Scholar
• Hsiao IL, Hsieh YK, Wang CF, et al. Trojan-horse mechanism in the cellular uptake of silver nanoparticles verified by direct intra- and extracellular silver speciation analysis. Environ Sci Technol. 2015;49:3813–3821.
   PubMed Web of Science ®Google Scholar
• Calabrese EJ. Hormesis: why it is important to toxicology and toxicologists. Environ Toxicol Chem. 2008;27:1451–1474.
   PubMed Web of Science ®Google Scholar
• Sthijns MM, Weseler AR, Bast A, et al. Time in Redox Adaptation Processes: From Evolution to Hormesis. Ijms. 2016;17:1649.
   Web of Science ®Google Scholar
• Karlsson HL, Cronholm P, Hedberg Y, et al. Cell membrane damage and protein interaction induced by copper containing nanoparticles-importance of the metal release process. Toxicology. 2013;313:59–69.
   PubMed Web of Science ®Google Scholar
• Fotakis G, Timbrell JA. Role of trace elements in cadmium chloride uptake in hepatoma cell lines. Toxicol Lett. 2006;164:97–103.
   PubMed Web of Science ®Google Scholar
• Wei L, Tang J, Zhang Z, et al. Investigation of the cytotoxicity mechanism of silver nanoparticles in vitro. Biomed Mater. 2010;5:044103.
   PubMed Web of Science ®Google Scholar
• McBeath R, Pirone DM, Nelson CM, et al. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell. 2004;6:483–495.
   PubMed Web of Science ®Google Scholar
• Louzao MC, Ares IR, Cagide E, et al. Palytoxins and cytoskeleton: an overview. Toxicon. 2011;57:460–469.
   PubMed Web of Science ®Google Scholar
• Saldaña L, Vilaboa N. Effects of micrometric titanium particles on osteoblast attachment and cytoskeleton architecture. Acta Biomater. 2010;6:1649–1660.
   PubMed Web of Science ®Google Scholar
• Beck GR, Sullivan EC, Moran E, et al. Relationship between alkaline phosphatase levels, osteopontin expression, and mineralization in differentiating MC3T3-E1 osteoblasts. J Cell Biochem. 1998;68:269–280.
   PubMed Web of Science ®Google Scholar
• Sun J, Li J, Li C, et al. Role of bone morphogenetic protein-2 in osteogenic differentiation of mesenchymal stem cells. Mol Med Rep. 2015;12:4230–4237.
   PubMed Web of Science ®Google Scholar
• Franceschi RT, Xiao G. Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways. J Cell Biochem. 2003;88:446–454.
   PubMed Web of Science ®Google Scholar
• Atkins GJ, Welldon KJ, Holding CA, et al. The induction of a catabolic phenotype in human primary osteoblasts and osteocytes by polyethylene particles. Biomaterials. 2009;30:3672–3681.
   PubMed Web of Science ®Google Scholar
• Lee NK, Choi YG, Baik JY, et al. A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood. 2005;106:852–859.
   PubMed Web of Science ®Google Scholar
• Boyce BF, Xing L. Functions of RANKL/RANK/OPG in bone modeling and remodeling. Arch Biochem Biophys. 2008;473:139–146.
   PubMed Web of Science ®Google Scholar
• Crotti TN, Smith MD, Findlay DM, et al. Factors regulating osteoclast formation in human tissues adjacent to peri-implant bone loss: expression of receptor activator NFkappaB, RANK ligand and osteoprotegerin. Biomaterials. 2004;25:565–573.
   PubMed Web of Science ®Google Scholar